| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-D0059 | Endovascular Thrombectomy for Distal MediUm Vessel Occlusion StroKe - an international randomized-controlled trial | clinical trial | medical devices | monocentric | A2 | Prof Marios Psychogios | University of Pittsburgh |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.06.2026 | |||||
| 2026-D0048 | Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study | clinical trial | medical devices | multicentric | A1 | Prof. Tobias Reichlin | Vektor Medical, Inc. |
Inselspital, University Hospital Bern, Bern University Hospital Basel, Cardiology, Petersgraben 4 |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.06.2026 | ||||
| 2026-D0044 | Executive Function Intervention for Children with Complex Congenital Heart Disease: A Randomised Control Study | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med., Beatrix Latal | University Children’s Hospital Zurich |
University Children’s Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 10.07.2026 | yes | ||||
| 2026-D0039 | Randomized Controlled Trial of the Auryon Atherectomy System Used in Combination with Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone Treating Infrapopliteal Lesions in Subjects More ... | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Aljoscha Rastan | AngioDynamics, Inc. |
Luzerner Kantonsspital, Dpt. Angiologie, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.06.2026 | |||||
| 2026-D0032 | Digitally assisted geriatric home-rehabilitation in older patients after hip surgery (GRIMSEL): a non-inferiority randomized controlled trial | clinical trial | medical devices | monocentric | A1 | PD Dr. Anna K. Eggimann | Inselspital |
Department of Geriatrics, Bern University Hospital and University of Bern, Bern |
Kantonale Ethikkommission Bern | 01.06.2026 | |||||
| 2026-D0028 | Effectiveness of two different desensitizing dental varnishes: A prospective, randomized split mouth clinical investigation | clinical trial | medical devices | monocentric | C2 | Dr. med. dent. Lydia Eberhard | Ivoclar Vivadent AG |
Ivoclar Vivadent AG, Schaan |
Kantonale Ethikkommission Zürich | 05.06.2026 | |||||
| 2026-D0026 | EnCompass Clamp and the AtriClip in Box Lesion and Left Atrial Appendage EXclusion Procedure for the Prevention of New Onset of Atrial Fibrillation | clinical trial | medical devices | monocentric | C1 | PROF. DR. MED. DR. H.C. OMER DZEMALI | AtriCure, Inc. |
Universitätsspital Zürich, Dept. for Cardiac Surgery, Zürich |
Kantonale Ethikkommission Zürich | 10.07.2026 | |||||
| 2026-D0020 | Prospektive multizentrische Evaluierung eines neuartigen Wirbelkörperersatzimplantates POSEIDON ST mit 3D gedruckten Endplatten | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Moritz C. Deml | SIGNUS Medizintechnik GmbH |
INSELSPITAL Bern, Bern |
Kantonale Ethikkommission Bern | 01.07.2026 | |||||
| 2026-D0018 | Bioabsorbable poly(L-lactide-co-glycolide) (PLGA) -based im-plants for pediatric fractures, a single center pilot study for os-teosynthesis with ActivaScrew™ in fractures of the Epicondylus ulnaris an More ... | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. habil. Markus Denzinger, MHBA | Ostschweizer Kinderspital |
Ostschweizer Kinderspital, 9000, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 02.04.2026 | yes | ||||
| 2026-D0017 | MK-1084-007 (Clinical Trial Title): Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy of MK 1084 in Combination With Subcutaneous Pembrolizumab and Berahy More ... | clinical trial | in vitro diagnostic medical devices CDx | multicentric | C1 | Dr. med. Sebastian Kraus | Merck Sharp & Dohme LLC |
Stadtspital Zürich Triemli, Zürich HFR Fribourg – Hôpital cantonal, Oncology, Chemin des Pensionnats 2-6 Hirslanden, Klinik für Hämatologie und Onkologie Hirslanden Zü |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Zürich | 23.06.2026 | ||||
| 2026-D0015 |
Pharmacoscopy for patients with refractory primary brain tumors: the EViDENCE-BT trial |
clinical trial | in vitro diagnostic medical devices IVD-MD | monocentric | C2 | Emilie Le Rhun, PD Dr. med. | University of Zurich, represented by |
University Hospital and University of Zurich, Department of Medical Oncology and Hematology, Zurich |
Kantonale Ethikkommission Zürich | 19.05.2026 | |||||
| 2026-D0014 |
A post-market, prospective, observational study to evaluate clinical benefit, performance and safety of Cochlear™ implants in an adult population: a master umbrella investigation A post-market, pro More ... |
clinical trial | medical devices | monocentric | A1 | Dr. Flurin Pfiffner | Cochlear Technology Center Belgium |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 07.07.2026 | |||||
| 2026-D0013 | A Randomized, Double-Blind, Phase 3 Study of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer | clinical trial | in vitro diagnostic medical devices CDx | multicentric | C1 | Dr. Anna Dorothea Wagner | Incyte Corporation |
CHUV, Lausanne University Hospital, Lausanne Inselspital- Universitaetsspital Bern, Bern HOCH Health Ostschweiz, Kantonsspital St. Gallen Rorschacher Strasse 95 |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS) | 06.05.2026 | ||||
| 2026-D0012 | Safety and performances of the LINEA cardiac pacing lead optimized for the implantation in interventricular septum | clinical trial | medical devices | monocentric | C2 | Pr. Haran Burri | SORIN CRM SAS (MicroPort CRM) |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 18.05.2026 | |||||
| 2026-D0009 | Clinician- and patient-reported outcome measures (ClinROs/PROMs) following implant placement with open vs submerged healing of native collagen membranes (BioGide® Compressed) | clinical trial | medical devices | monocentric | A1 | Dr. med.dent. Marina Siegenthaler | Zahnarzt Praxis GRIMM Zahnärzte |
Zahnarzt Praxis GRIMM Zahnärzte, Horgen |
Kantonale Ethikkommission Zürich | 29.04.2026 | |||||
| 2026-D0008 | Basel Kosten-Effektivitäts-Trial: Drug-coated balloon vs. drug-eluting stent strategy in high-risk patients with coronary artery disease | clinical trial | medical devices | multicentric | A1 | Prof Gregor Leibundgut | B.BRAUN Melsungen AG - Vascular Systems |
Universitätsspital Basel, Basel Stadtspital Zürich Triemli, Birmensdorferstrasse 497 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 20.05.2026 | ||||
| 2026-D0007 | The Fourth Left Atrial Appendage Occlusion Study: (LAAOS-4) | clinical trial | medical devices | monocentric | A2 | Prof. Dr. med. Christian Sticherling | Hamilton Health Sciences Corporation through its Population Health Research Institute (PHRI) |
Univeristätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.04.2026 | |||||
| 2026-D0006 | Exploration of the functional effect of modified gain precalculation on soft speech intelligibility | clinical trial | medical devices | monocentric | A1 | Josephine Hollenbach | Sonova AG |
Sonova AG, Stäfa |
Kantonale Ethikkommission Zürich | 17.04.2026 | |||||
| 2026-D0005 | Diagnostic Protocol for Evaluating the Clinical Performance of VENTANA FOLR1 (FOLR1-2.1) IUO Assay in Determining FOLR1 Status in Tumor Specimens from Platinum-Resistant Ovarian Cancer Patients in Ast More ... | clinical trial | in vitro diagnostic medical devices CDx | multicentric | C1 | Prof. Dr. Viola Heinzelmann-Schwarz | Ventana Medical Systems, Inc. (Roche Tissue Diagnostics [RTD]) |
Universitätsspital Basel, Basel Spital STS AG - Spital Thun - Onkologie- und Hamatologiezentrum, Thun Spital Thurgau-Kantonsspital Muensterlingen, Spitalcampus 1 Kantonsspital St. Gallen, Rorschacher More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 27.05.2026 | ||||
| 2026-D0004 | Multicentric randomized single-blinded controlled clinical trial comparing additively and subtractively manufactured implant supported fixed dental prostheses | clinical trial | medical devices | monocentric | A1 | Dr. Kevser Pala | Harvard School of Dental Medicine |
University of Zurich, Clinic of Reconstructive Dentistry, Zurich |
Kantonale Ethikkommission Zürich | 19.06.2026 | |||||