| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-00004 | Chronic colonization by the commensal mouse gut protozoa Tritrichomonas spp. in C57BL/6N mice instigates a persistent inflammatory gut microenvironment, impacting glycemic control and insulin secretio More ... | personal data/biological material | monocentric | PD Dr. med Claudia Cavelti-Weder | Departement Biomedizin |
Departement Biomedizin, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.02.2024 | |||||||
| 2024-00002 | Cognitive-motor training on a labile surface in stroke inpatients: feasibility and preliminary effects | clinical trial | other clinical trials | monocentric | A | Eleftheria Giannouli | ETH Zurich |
ETH Zurich, Zurich |
Ethikkommission Ostschweiz (EKOS) | 29.02.2024 | Study has ended | ||||
| 2024-00001 | Traditional masculinity and male-specific risk factors for suicidal ideation and behaviors in men: Investigating real-time associations between affect, emotion regulation and traditional masculinity w More ... | non clinical, involving persons | monocentric | A | Dr. phil. Andreas Walther | University of Zurich |
University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 06.12.2024 | ||||||
| 2023-D0122 |
A prospective single center open label study assessing intraocular pressure measurements using a novel sensing contact lens-based device as compared to standard tonometry, in open angle glaucoma and More ... |
clinical trial | medical devices | monocentric | C2 | Pr (US Denver) Kaweh Mansouri | Sensimed SA |
Clinique de Montchoisi, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.02.2024 | |||||
| 2023-D0121 | Randomized Controlled Clinical Trial on the Application of Heli-FX EndoAnchors in Conjunction With the Endurant II/IIs Endograft in Infrarenal Aortic Aneurysms With a Wide Infrarenal Neck (HERCULES Tr More ... | clinical trial | medical devices | monocentric | A1 | Dr François Saucy | Rijnstate Hospital |
Ensemble Hospitalier de la Côte, Morges |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.03.2024 | |||||
| 2023-D0120 |
First experience with the performance of Geistlich Bio-Oss® Flow (fDBBM-C) in periodontal intrabony defects |
clinical trial | medical devices | monocentric | C2 | Prof. Dr. Anton Sculean | Geistlich Pharma AG |
University of Bern, clinic for Periodontology, Bern |
Kantonale Ethikkommission Bern | 22.05.2024 | |||||
| 2023-D0119 | A randomized, open-label, multicentric, two-arm pivotal trial of SonoCloud-9 combined with carboplatin (CBDCA) vs standard of care lomustine (CCNU) or temozolomide (TMZ) in patients undergoing planned More ... | clinical trial | combination drugs/devices | multicentric | C2 | Adjunct Professor Andreas Felix Hottinger | CARTHERA |
Centre Hospitalier Universitaire Vaudois (CHUV), Department of Clinical Neurosciences, Lausanne Department of Neurosurgery, Bern |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern | 04.07.2024 | ||||
| 2023-D0118 | Effect of implant surface material and topography on bone regeneration: A two-centre, parallel-group, pilot study | clinical trial | medical devices | monocentric | A1 | Dr. med. dent. Anina Zürcher | Queen Mary University of London (QMUL) |
Clinic of Reconstructive Dentistry, Centre of Dental Medicine, University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 05.03.2024 | |||||
| 2023-D0117 | Brain circuitry therapeutics for schizophrenia – A randomized controlled clinical study to treat negative symptoms of schizophrenia using non-invasive stimulation of the cerebellum | clinical trial | medical devices | monocentric | C1 | Prof. Indrit Bègue | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 15.05.2024 | |||||
| 2023-D0116 | Protocol-optimization in computed tomography for the quantification of bone mineral density (BMD) | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Hatem Alkadhi | Diagnostic and Interventional Radiology University Hospital Zurich |
Diagnostic and Interventional Radiology University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 23.01.2024 | |||||
| 2023-D0113 | PEERLESS II - Randomized Controlled Trial of FlowTriever vs. Anticoagulation alone in Pulmonary Embolism | clinical trial | medical devices | multicentric | A1 | Dr. Gregor Leibundgut | Inari Medical Europe GmbH |
Universitätsspital Basel, Basel Inselspital Bern, Bern Luzerner Kantonsspital, Spitalstrasse |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.01.2024 | ||||
| 2023-D0112 | Internet-Based Treatment for Depression: A Randomized Trial Comparing Therapist Support and Peer-Support Using an Online Forum. | clinical trial | medical devices | monocentric | A1 | Prof. Dr. Chantal Martin-Soelch | University of Fribourg |
University of Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.05.2024 | |||||
| 2023-D0111 | A novel endoscopic attachment cap for benign esophageal stricture dilation in children: a randomized, multicentric pilot study. | clinical trial | medical devices | multicentric | A1 | Dr. med. Vasiliki Spyropoulou | University Children’s Hospital Zurich |
University Children’s Hospital, Zurich Universitäts-Kinderspital beider Basel, Spitalstrasse 33, 4056 Basel, Switzerland |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.03.2024 | yes | |||
| 2023-D0110 | Brain aging – a comparative study in healthy and patients with Multiple Sclerosis as model of a chronic neuroinflammatory disorder | clinical trial | medical devices | monocentric | C2 | PD Dr. med Robert Hoepner | Inselgruppe AG |
Inselgruppe AG, Bern |
Kantonale Ethikkommission Bern | 07.03.2024 | |||||
| 2023-D0109 | Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect (ASCENT ASD Study) | clinical trial | medical devices | multicentric | C2 | Prof Dr med Oliver Kretschmar | atHeart Medical LLC |
KISPI, Zurich CHUV, Rue de Bugnon 21 |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.05.2024 | yes | |||
| 2023-D0108 | PREPICare: Assessment of an Innovative Air Mattress on Critically Ill Infants | clinical trial | medical devices | monocentric | C2 | Prof. Dr. med. Barbara Brotschi Audenblatten | Empa |
Universitätskinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 19.03.2024 | yes | Study has ended | |||
| 2023-D0107 | A Non-Randomized, Prospective or Retrospective, Open-Label, Multi-Center, Observational Clinical Study with Two Arms to Further Evaluate Safety and Performance of the NEXUS® Aortic Arch Stent Graft Sy More ... | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Mario Lachat | Endospan ltd |
Hirslanden Klinik, Zürich |
Kantonale Ethikkommission Zürich | 12.12.2023 | |||||
| 2023-D0106 | Exploratory study of NeuroLF, an investigational medical device without CE-marking for PET imaging of the human brain | clinical trial | medical devices | monocentric | C2 | Prof. Dr. Martin Hüllner | Positrigo AG |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 14.05.2024 | |||||
| 2023-D0105 | A mobile application as supportive treatment of endometriosis: the effect on quality of life and endometriosis-associated pain. A randomized controlled trial. | clinical trial | medical devices | monocentric | A1 | Dr. med. Marietta Gulz | University Hospital of Obstetrics and Gynaecology |
University Hospital of Bern Department of Gynecology and Obstetrics, Bern |
Kantonale Ethikkommission Bern | 20.12.2023 | |||||
| 2023-D0103 | Safety and performance of the Biphasic Plate Distal Femur: A multicenter case series | clinical trial | medical devices | multicentric | A1 | Dr.Med Christian Michelitsch | 41medical AG |
Kantonsspital Graubunden, Chur University Hospital Basel, Department of Orthopaedics and Traumatology Unive Universitätsspital Zürich, Rämistrasse 100 |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.01.2024 | ||||