| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-01956 | Distress and suicidality of health and social care professionals: experiences, risk profiles and support needed | non clinical, involving persons | monocentric | A | Prof. Dolores Angela Castelli Dransart | HETS-FR/HES-SO FR |
HETS-FR/HES-SO FR, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.12.2022 | ||||||
| 2022-01954 | The pedicled scapular artery perforator flap for simple local coverages to complex lymphatic reconstructions: clinical experience with 22 cases. | personal data/biological material | monocentric | Prof. Dr. med Mario Scaglioni |
LUKS, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.11.2022 | ||||||||
| 2022-01951 | AMAZE-lung: Amivantamab, lazertinib and bevacizumab in patients with EGFR-mutant advanced non-small cell lung cancer with progression on previous third generation EGFR TKI | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. Martin Früh | ETOP IBCSG Partners Foundation |
Kantonsspital St. Gallen, St.Gallen Universitätsklinik für Medizinische Onkologie, Inselspital, Bern IOSI, Bellinzona |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Bern, Comitato etico cantonale Ticino | 26.01.2023 | |||
| 2022-01950 | Investigating Inflammasomes in Myeloid neoplasms and Ageing | personal data/biological material | monocentric | Dr. Ramanjaneyulu Allam | Inselspital, |
Inselspital/University Bern, Bern |
Kantonale Ethikkommission Bern | 13.01.2023 | |||||||
| 2022-01949 | Syndrome coronarien aigu et pontage aorto-coronarien (SCAPAC): quel traitement antiplaquettaire en période postopératoire ? | personal data/biological material | monocentric | Dr. Sarah Hugelshofer | Bureau du promoteur de recherche du CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.12.2022 | |||||||
| 2022-01948 | Quantitative MRI susceptibility mapping in children with focal epilepsy | non clinical, involving persons | monocentric | A | Prof. Dr. med. Luca Remonda | KSA |
KSA, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.01.2023 | yes | |||||
| 2022-01947 | Quantitative MRI susceptibility mapping (QSM) in patients with Transient Ischemic Attacks (TIA) | non clinical, involving persons | monocentric | A | Prof. Dr. med. Luca Remonda | KSA |
KSA, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.12.2022 | ||||||
| 2022-01944 | Analyse von Risikofaktoren für Komplikationen nach laparoskopischer Adrenalektomie | personal data/biological material | monocentric | Dr.med. Ioannis Lazaridis | Chirurgie Zentrum St. Anna |
Clarunis Universitäres Bauchzentrum, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.12.2022 | |||||||
| 2022-01942 | Establishment of an ex vivo human lung tissue model to study viral-bacterial co-infections | personal data/biological material | monocentric | Prof Dr Mirco Schmolke | HUG |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 15.12.2022 | |||||||
| 2022-01940 | Characterization and evolution of unclassified inflammatory bowel disease (IBDU) in the Swiss IBD chort study (SIBDCS) | personal data/biological material | monocentric | PD Valérie Pittet | Unisanté |
Unisanté, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.12.2022 | |||||||
| 2022-01939 | A retrospective study on the role of soluble CD25 in autoimmune and inflammatory diseases, with a focus on sarcoidosis. | personal data/biological material | monocentric | Dr. Denis Comte | CHUV - Immunologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.12.2022 | |||||||
| 2022-01938 | Impaired organ perfusion and impact on citrate accumulation during renal replacement therapies | personal data/biological material | monocentric | Prof. Dr. med. Sascha David | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 02.12.2022 | |||||||
| 2022-01936 | Evaluation of image quality in the aorta of contrast-enhanced magnetic resonance angiography using TWIST and GRASP | personal data/biological material | monocentric | PD Dr. Bernd Jung | Inselspital Bern |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 13.01.2023 | |||||||
| 2022-01935 | Clinical feasibility evaluation of a feedback control system for heart rate in patients after stroke | non clinical, involving persons | monocentric | A | Prof. Dr. Kenneth J. Hunt | Berner Fachhochschule |
Reha Rheinfelden, Salinenstrasse 98, CH-4310 Rheinfelden, Rheinfelden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.12.2022 | ||||||
| 2022-01934 | Implementation and optimization of the Schirmer test to quantify rhinitis sicca during sinonasal cancer treatment | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Michael B. Soyka | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 20.12.2022 | |||||
| 2022-01933 | Analytical validation of an ultra-fast NGS assay for molecular profiling of solid tumors | personal data/biological material | monocentric | Ilaria Alborelli |
Institute of Pathology of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.12.2022 | ||||||||
| 2022-01931 | ASSURE: An Open Label Long-Term Study to Evaluate the Safety and Tolerability of Seladelpar in Subjects with Primary Biliary Cholangitis (PBC) CB8025-31731 (ASSURE) | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. Dr. med., MBHA/Andreas Emanuel/Kremer | CymaBay Therapeutics, Inc. |
University Hospital Zurich/Gastroenterology and Hepatology, Zurich |
Kantonale Ethikkommission Zürich | 02.12.2022 | ||||
| 2022-01928 | Evaluation of response according to the Response Criteria for Intratumoral Immunotherapy in Solid Tumors in patients with locally advanced non-melanoma skin cancer, treated with intralesional talimoge More ... | personal data/biological material | monocentric | Dr. med. Dr. sc. med. Egle Ramelyte | Dermatologische Klinik, UniversitätsSpital Zürich |
Department of Dermatology, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 02.12.2022 | |||||||
| 2022-01927 |
Treatment outcomes, quality of life and supportive care needs in patients with familial high risk for malignant diseases |
non clinical, involving persons | monocentric | A | Katrin Breitling | Medizinische Unversität Wien |
Brustgesundheitszentrum, Schaffhausen |
Kantonale Ethikkommission Zürich | 24.01.2023 | ||||||
| 2022-01925 | Electromyographic and biomechanical analysis of the static lunge exercise using different speed and step length conditions | non clinical, involving persons | monocentric | A | Mirjam Douma, MSc PT | Schulthess Clinic |
Schulthess Clinic, Zürich |
Kantonale Ethikkommission Zürich | 02.12.2022 | ||||||