| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-00851 | MK-4884-001: A Phase 1 Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of MK-4884 in Participants with Advanced/Metastatic Solid Tumors | clinical trial | drugs | phase 1 | multicentric | C | Dr. med. Martina Imbimbo | Merck Sharp and Dohme LLC |
ENTE OSPEDALIERO CANTONALE (EOC), Istituto Oncologico Svizzera Italiana (IOSI), Bellinzona HOCH Health Ostschweiz, Kantonsspital St.Gallen, St. Gallen CHUV, Oncology Department, Lausanne |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 01.07.2026 | |||
| 2026-00849 |
Maternal and infant nutrition Diurnal and diet-associated variability of nutrients in human milk: Secondary analysis of a longitudinal metabolic balance study in lactating women |
personal data/biological material | monocentric | Dr. sc. Dr. med. Daniela Paganini | University Children's Hospital Zurich |
University Children's Hospital Zurich - Eleonore Foundation, Zürich |
Kantonale Ethikkommission Zürich | 30.06.2026 | |||||||
| 2026-00848 | Emergency Departments Workload during Heatwaves in Canton of Ticino, Switzerland (HeatED-TI 1.0) | personal data/biological material | monocentric | Dr. med. Ilenia Mascherona | Emergency Department, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale |
Emergency Department, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 04.05.2026 | |||||||
| 2026-00847 | Association of dietary intake with inflammation, obesity and metabolic risk among Swiss children and adolescents | personal data/biological material | monocentric | Prof. Suzanne Suggs | Università della Svizzera italiana |
Università della Svizzera italiana (USI), Lugano |
Comitato etico cantonale Ticino | 04.05.2026 | |||||||
| 2026-00845 | Estimating lifestyle, genetic and biological risk factors for cognitive impairment incidence | personal data/biological material | monocentric | Professor Giovanni B. Frisoni | University of Geneva |
HUG, GENÈVE |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.06.2026 | |||||||
| 2026-00843 | A Sequential Phase 2/3, Single-Arm, Open-Label Study in Adults Followed by a Randomized, Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adu More ... | clinical trial | drugs | phase 3 | multicentric | B | Prof. Dr. med. Britta George | Apellis Pharmaceuticals, Inc. |
Universitätsspital Zürich, Zürich Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne Universitäts-Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.06.2026 | yes | ||
| 2026-00841 | Automated and Objective Detection of Binocular Vision with a VR-based medical device | personal data/biological material | monocentric | PD Dr. med. Dr. sc. nat. Mathias Abegg | ONOVIS |
Onovis Augenpraxis, Bern |
Kantonale Ethikkommission Bern | 01.06.2026 | |||||||
| 2026-00839 | Harmonisierung der Atmung durch Musiktherapie und deren Einfluss auf Angst, Lebensqualität und autonomer Dysfunktion bei M. Parkinson | clinical trial | other clinical trials | monocentric | A | Dr. med. Siegward Elsas | Klinik Arlesheim |
Klinik Arlesheim, Arlesheim |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.05.2026 | |||||
| 2026-00837 | EASY-MAZE: Evaluation of Ablation-related biomarker release in cardiac SurgerY: MAZE procedures during mitral valve surgery | personal data/biological material | multicentric | PD Dr. med. David Reineke | Inselspital Bern |
Inselspital Bern, Universitätsklinik für Herzchirurgie, Bern Klinik für Herzchirurgie Allianz Herzchirurgie Zürich-St. Gallen, Zürich |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 18.06.2026 | ||||||
| 2026-00833 | Impact of sacral neuromodulation on sexual function in men and women | non clinical, involving persons | monocentric | A | Nady Assayed Leonardi | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 15.07.2026 | ||||||
| 2026-00832 | Pediatric Radiology Intelligent Structured Reporting and Measurement Automation Tools using AI | personal data/biological material | monocentric | Dr. Friederike Prüfer | Universitäts-Kinderspital beider Basel (UKBB) |
Universitäts-Kinderspital beider Basel (UKBB), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.05.2026 | |||||||
| 2026-00828 | Enhancing Pedicle Screw Augmentation Decision: Interactions between screw insertion work and stability test in cadaveric lumbar vertebrae | deceased persons | monocentric | Dr. Ivan Zderic | AO Research Institute Davos |
AO Research Institute Davos, Davos |
Kantonale Ethikkommission Zürich | 26.06.2026 | |||||||
| 2026-00826 | Detecting and Addressing Vaccination Gaps in Children with Chronic Health Conditions | personal data/biological material | multicentric | Ass. Prof. Dr. Dr. sc. med. Nora Fritschi | Universität Luzern |
Universität Luzern, Luzern Kantonsspital Winterthur - Children’s Hospital Winterthur, Winterthur |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 06.05.2026 | ||||||
| 2026-00824 |
Orale Gesundheit in der Schwangerschaft Eine prospektive Studie - Patientinnenbefragung anhand eines Fragebogens |
non clinical, involving persons | monocentric | A | Professor Olav Lapaire | Universitätsspital Basel |
Frauenklinik Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.07.2026 | ||||||
| 2026-00822 | Bronchodilator response in former preterm infants | personal data/biological material | monocentric | PD Dr. med. Elias Seidl | University Children’s Hospital Zurich |
Department of pulmonology University Children’s Hospital Zurich Lenggstrasse 30, Zürich |
Kantonale Ethikkommission Zürich | 26.06.2026 | |||||||
| 2026-00821 | Companion Diagnostics: Clinical Performance of the VENTANA PD-L1 (SP263) CDx Assay for Determining PD-L1 Expression Levels in Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Specimens More ... | personal data/biological material | monocentric | Dr. Erwan Gouranton | Roche Tissue Diagnostics (RTD) |
Labcorp CLS, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.05.2026 | |||||||
| 2026-00819 | Comorbid insomnia and sleep apnea (COMISA): can early treatment of insomnia increase adherence to CPAP therapy? | clinical trial | other clinical trials | monocentric | A | Dr Geoffroy Solelhac, MD PhD | Centre Hospitalier Universitaire Vaudois CHUV |
Centre du sommeil (CIRS), CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.07.2026 | |||||
| 2026-00818 | Identification of risk factors for Clostridioides difficile infection among adult inpatients at CHUV (Lausanne) comparing machine learning and classical regression, 2020–2025: a retrospective EHR coho More ... | personal data/biological material | monocentric | Prof Benoit Guery | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.05.2026 | |||||||
| 2026-00817 |
IM0620001: A Phase 1/2a, Open-label, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of BMS-986528 in Participants with Refractory Rheuma More ... |
clinical trial | drugs | phase 1/2 | multicentric | C | PD Dr. Kim Lauper | Bristol-Myers Squibb Services Unlimited Company |
Hôpitaux Universitaires Genève (HUG), Geneve Universitätsklinik für Rheumatologie und Immunologie, Bern |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Bern | 18.06.2026 | |||
| 2026-00816 |
Long-Term Effectiveness and Safety of Anti-CGRP Monoclonal Antibodies in Patients with Migraine: A 5-Year Retrospective Multicenter Cohort Study EOC.INSI.HA.2602 |
personal data/biological material | multicentric | Prof. dr.ssa med. Chiara Zecca | Ente Ospedaliero Cantonale, Ospedale Regionale di Lugano |
Ente Ospedaliero Cantonale, Ospedale Regionale di Lugano, Lugano Inselspital, Berna Kantonalspital Luzern, Luzern Universitätsspital Basel, Basel Universitätsspital Zürich, Zürich Bellevue Medical Gro More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 07.05.2026 | ||||||