| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-02084 | Perinatal Mental Health Screening and Clinical Outcomes: A Retrospective Observational Study at the Department of Gynecology, Lucerne Cantonal Hospital | personal data/biological material | monocentric | Christian Braun | LUKS Luzern |
Womens Hospital LUKS Luzern, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.12.2025 | |||||||
| 2025-02083 | Traumata der oberen Extremitäten - Follow-Up-Studie zu Therapiestrategie und Outcome | non clinical, involving persons | monocentric | A | Dr. med. Christiane Barthel |
Traumatologie USZ, Zürich |
Kantonale Ethikkommission Zürich | 18.12.2025 | |||||||
| 2025-02082 | Are medications affecting the risk of hospitalisations in psychiatric patients during heat episodes? A case study in a Swiss Clinic. | personal data/biological material | multicentric | Associate Professor Ana M. Vicedo Cabrera | Universität Bern |
Universität Bern, Bern Privatiklink Meiringen, Meiringen |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 23.12.2025 | ||||||
| 2025-02080 | Long-term effectiveness of apical surgery using two materials for retrograde root canal obturation: A 10-year retrospective study | non clinical, involving persons | monocentric | A | PD Dr. Clemens Raabe | Department of Oral Surgery and Stomatology |
Klinik für Oralchirurgie und Stomatologie, zmk Bern, Bern |
Kantonale Ethikkommission Bern | 02.12.2025 | ||||||
| 2025-02079 | Complication, clinical and radiological outcomes after reverse shoulder arthroplasty. A multicentric, retrospective and comparative study | personal data/biological material | monocentric | Dr.med. David Hollo | Cantonal Hospital Aarau AG |
Cantonal Hospital Aarau AG, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.12.2025 | |||||||
| 2025-02076 | Risk of diabetes mellitus in patients with giant cell arteritis treated with or without tocilizumab | personal data/biological material | monocentric | Lisa Christ | Universitätsklinik für Rheumatologie und Immunologie, Inselspital, Universität Bern, Insel Gruppe AG |
Universitätsklinik für Rheumatologie und Immunologie, Inselspital, Universität Bern, Insel Gruppe AG, Bern |
Kantonale Ethikkommission Bern | 21.11.2025 | |||||||
| 2025-02074 | Improving Kidney Function Assessment in Palliative Care: A Retrospective Comparison of Creatinine- and Cystatin-C-Based eGFR and Its Impact on Clinical Decision-Making | personal data/biological material | monocentric | Prof. Dr. Christopher Böhlke | Unispital Basel |
Universitätsspital Basel, Frauenklinik, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.01.2026 | |||||||
| 2025-02069 | Sex Disparities in Sudden Cardiac Death | personal data/biological material | monocentric | Katarzyna Michaud | UNIL - URMF |
University Center of Legal Medicine, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.11.2025 | |||||||
| 2025-02067 |
EORTC PROLoNg PROLoNg: Pembrolizumab and Radiotherapy for OLigometastatic squamous cell carcinoma of the head and Neck: a randomized phase III study |
clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Panagiotis Balermpas | EORTC |
Universitätsspital Zürich, Zürich Inselspital Bern, Bern Kantonsspital Aarau, Aarau Luzerner Kantonsspital, Luzern Universitätsspital Basel, Basel HOCH Health Ostschweiz, St. Gallen IOSI - Istituto On More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 20.01.2026 | |||
| 2025-02064 | Localization of pseudarthroses following conservatively treated blunt thoracic trauma. | personal data/biological material | monocentric | Dr. med. Michail Galanis | Inselspital Bern |
Department for thoracic surgery, Bern |
Kantonale Ethikkommission Bern | 04.12.2025 | |||||||
| 2025-02061 | Potential risk indicators of implant loss: a university-representative case control study | personal data/biological material | monocentric | Clemens Raabe | Klinik für Oralchirurgie und Stomatologie |
Klinik für Oralchirurgie und Stomatologie, zmk Bern, Bern |
Kantonale Ethikkommission Bern | 03.12.2025 | |||||||
| 2025-02059 | Local and systemic safety and tolerability of ascending doses of TOP-N53, a nitric oxide (NO)-releasing phosphodiesterase-5 (PDE5) inhibitor, administered topically, on wound in patients with digital More ... | clinical trial | drugs | phase 2 | monocentric | C | PD Dr. med. Dr. rer. nat. Ulrich Gerth | Topadur Pharma AG |
Reha Rheinfelden, Rheinfelden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.11.2025 | ||||
| 2025-02055 | Outcome after ileo-pouch anal anastomosis (IPAA) | non clinical, involving persons | monocentric | A | Pr MD Dieter Hahnloser | CHUV - Chirurgie viscérale |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.10.2025 | ||||||
| 2025-02052 | Reverse Cherry Picking in Large Randomized Controlled Trials - Results from the DISTAL Trial | personal data/biological material | multicentric | Prof. Dr. Marios-Nikos Psychogios |
Universitätsspital Basel, 4031 Basel Inselspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 08.12.2025 | |||||||
| 2025-02051 | Presenting signs and symptoms of congenital portosystemic shunts | personal data/biological material | monocentric | Prof. Valérie McLin | Geneva University Hospitals |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.10.2025 | |||||||
| 2025-02048 | TRI0394 - Evaluation of B7H4 Protein Expression And Heterogeneity by IHC in FFPE Tumor Samples following Therapy Intervention in Advanced Breast Cancer Population | personal data/biological material | monocentric | Ernesta Dammassa | Novartis Pharma AG - Biomedical Research |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.10.2025 | |||||||
| 2025-02047 | Tooth Structure Loss Across Contemporary Preparation Designs: A Retrospective 3-D STL Analysis of Anterior and Posterior Restorations | personal data/biological material | monocentric | PD Dr. med. dent. Pune Paqué | Universität Zürich |
Universität Zürich, Zürich |
Kantonale Ethikkommission Zürich | 28.11.2025 | |||||||
| 2025-02044 | The Anatomy of Ulnar Artery Perforators in the Distal Forearm and their Clinical Significance for Flap Design: A Cadaveric Study | deceased persons | monocentric | PD Dr. med Thomas Giesen | Luzerner Kantonsspital |
Skills Lab, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.12.2025 | |||||||
| 2025-02040 | Long-Term Outcomes of Lymph Reconstructive Procedures in Lymphedema Patients: Evaluation Using Indocyanine Green Near-Infrared Fluorescence Imaging and Volume Measurement | non clinical, involving persons | monocentric | B | Prof. Dr. med. Nicole Lindenblatt | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 18.12.2025 | ||||||
| 2025-02039 | Impact of collateral status on the risk of hemorrhagic transformation after revascularisation therapy in patients with ischemic stroke in the late time window | personal data/biological material | monocentric | Tolga Dittrich, MD PhD | HOCH Cantonal Hospital St. Gallen |
Department of Neurology, HOCH Cantonal Hospital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 09.10.2025 | |||||||