| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-00140 | Comparing the Incidence and Extent of Post-Induction Hypotension between Titration and Conventional Induction with Propofol TCI in Adults Undergoing Non-Cardiac Surgery – a Retrospective Cohort Study | personal data/biological material | monocentric | Prof. Dr. med. Salome Dell-Kuster | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 31.01.2025 | |||||||
| 2025-00139 | Retrospective study of aspiration mechanical thrombectomy with RED43 reperfusion catheters for medium or distal vessel occlusions – a multicenter retrospective case series | personal data/biological material | monocentric | Prof. Dr. Marios-Nikos Psychogios | Universitätsspital Basel |
Universitätsspital Basel, 4031 Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.02.2025 | |||||||
| 2025-00138 | sCD14 as marker in cardiac sarcoidosis | personal data/biological material | monocentric | Prof. Dr. med. Camillo Ribi | CHUV |
CHUV, Division of immunology and allergy, Department of medecine, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 25.02.2025 | |||||||
| 2025-00137 | COMPAGNION DIAGNOSTICS: Performance of VENTANA PD-L1 (SP263) CDx Assay for Determining PD-L1 Expression Level in Non-small Cell Lung Cancer Specimens from the Phase III Study SUNRAY-01 | personal data/biological material | monocentric | Dr Olivier Venzin | Roche Tissue Diagnostics |
Labcorp CLS, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 30.01.2025 | |||||||
| 2025-00136 | Méningites à listeria monocytogenes et autres agents bactériens chez l’adulte: une analyse comparative | personal data/biological material | monocentric | Prof. Gilbert Greub | CHUV |
Lausanne University Hospital, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 25.02.2025 | |||||||
| 2025-00135 | Personalized Blood Pressure Management in Patients with Stroke: Biological Sex Matters | personal data/biological material | monocentric | PD Dr Giovanna Brandi | Institute for Intensive Care, University Hospital Zurich, Zurich Switzerland and University of Zurich, Zurich, Switzerland |
University Hospital of Zurich, Institute for Intensive Care, Zürich |
Kantonale Ethikkommission Zürich | 09.05.2025 | |||||||
| 2025-00134 | Pre- versus postoperative individualized healing abutment fabrication in immediate implant placement - a randomized controlled trial | clinical trial | other clinical trials | monocentric | A | Dr. Clemens Raabe, MAS | Klinik für Oralchirurgie und Stomatologie |
Klinik für Oralchirurgie und Stomatologie, zmk Bern, Universität Bern, Bern |
Kantonale Ethikkommission Bern | 23.04.2025 | |||||
| 2025-00133 | CHAMELEON: from CHIP and CCUS to AML: Evolution of leukaemic entities and onset of neoplasia | personal data/biological material | monocentric | Prof. Stefan Balabanov | University Hospital Zürich |
University Hospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 19.08.2025 | |||||||
| 2025-00132 | Congenital cytomegalovirus (cCMV) infection after maternal primary or non-primary infection in the Zurich area 2010-2024– a retrospective observational study | personal data/biological material | multicentric | Dr. med. Paolo Paioni | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital Zürich, Zürich Universitätsspital Zürich, Klinik für Geburtshilfe, Zürich Universitätsspital Zürich, Klinik für Neonatologie, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 10.06.2025 | ||||||
| 2025-00131 |
Exploratory study for the differential diagnosis of aplasia using Marrow Quant 2.0 and DeepMarrow digital hemopathology tools |
personal data/biological material | monocentric | Professor Olaia Naveiras | Centre Hospitalier Universitaire Vaudois |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.07.2025 | |||||||
| 2025-00130 | Care4Carers – Evaluating a Kinaesthetics-based Educational Program for Family Caregivers | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Heidrun Gattinger | OST Ostschweizer Fachhochschule |
OST Ostschweizer Fachhochschule, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 13.02.2025 | yes | ||||
| 2025-00129 | Radiation exposure from coronary CT angiography in a real-world setting. | personal data/biological material | monocentric | Prof. Dr. med. Oliver Gämperli | HerzKlinik Hirslanden |
HerzKlinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 04.04.2025 | |||||||
| 2025-00128 |
Ascertaining the impact of adjuvant radiotherapy in early-stage, risk factor-positive oral cavity squamous cell carcinoma, and evaluating patterns of failure |
personal data/biological material | monocentric | Prof. Dr. med. Olgun Elicin | University of Oklahoma |
Inselspital Bern, Universitätsklinik für Radio-Onkologie, 3010 Bern |
Kantonale Ethikkommission Bern | 04.03.2025 | Study has ended | ||||||
| 2025-00127 | FRI-OUT: Outcome analysis in fracture-related infections | personal data/biological material | monocentric | Dr. med. Noémie Reinert | University Hospital |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.02.2025 | |||||||
| 2025-00126 | Breast cancer with low risk of local recurrence: partial and accelerated radiation with Three-Dimensional conformal radiotherapy (3DCRT) versus standard radiotherapy after conserving surgery (Phase II More ... | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Thomas Zilli | Oncological Radiotherapy Operative Unit - Data Center Office, Clinical Trials Office, Integrated Department of Oncology, Hematology and Pulmonary Disease, Modena University Hospital |
IOSI, Bellinzona |
Comitato etico cantonale Ticino | 24.09.2009 | |||||
| 2025-00125 | C-type_PFX - Damage-control orthopedics for patients with vertically unstable pelvic ring injuries in Switzerland | personal data/biological material | monocentric | Dr. med. Nicola Bless | University Hospital |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.11.2025 | |||||||
| 2025-00124 | Ultrasonic investigation of gastric retention in patients with impaired stomach/gastric emptying objectified with MRI volumetry | clinical trial | other clinical trials | monocentric | A | Professor Dr. med. Christoph Gubler | University Hospital Zurich |
Triemli Hospital, Zurich |
Kantonale Ethikkommission Zürich | 21.11.2025 | |||||
| 2025-00123 | Reliability of the shoulder isometric force test (SHIFT) protocol | non clinical, involving persons | monocentric | A | Dr. Ursina Arnet | Swiss Paraplegic Research |
Schweizer Paraplegiker Forschung, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.03.2025 | Study has ended | |||||
| 2025-00122 | 1456-0001: Phase I open-label, dose escalation trial of BI 1831169 monotherapy and in combination with an anti-PD-1 mAb in patients with advanced or metastatic solid tumors. | clinical trial | pathogenic organisms / gmo | multicentric | C | Dr. med Thibaud Kössler | Boehringer Ingelheim International GmbH |
Hôpitaux Universitaires de Genève, Geneve Inselspital, Universitätsspital Bern, Bern |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Bern | 15.07.2025 | ||||
| 2025-00121 | “Exploring the prevalence, surgical therapy and oncological outcome of endometriosis in gynecological cancer patients: a retrospective analysis” | personal data/biological material | monocentric | PD. Dr. med. Franziska Siegenthaler | Inselspital Frauenklinik Bern |
Inselspital Frauenklinik Bern, Bern |
Kantonale Ethikkommission Bern | 02.04.2025 | |||||||