| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-01056 | Biomechanical Evaluation of Different Fixation Methods for Anterior Cruciate Ligament Avulsion Fractures in Posteromedial Tibial Plateau Fractures | deceased persons | monocentric | Dr. Ivan Zderic | AO Research Institute Davos |
AO Research Institute Davos, Davos |
Kantonale Ethikkommission Zürich | 11.07.2025 | Study has ended | ||||||
| 2025-01055 | Identification of interstitial signaling pathways in pruritus | personal data/biological material | monocentric | Prof. Dr. med. Andreas Kremer, PhD | University Hospital Zürich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 06.03.2026 | |||||||
| 2025-01053 | Évaluation radiologique des variations anatomiques du foramen spinosum et leur potentiel impact sur le traitement des hématomes sous-duraux chroniques. | personal data/biological material | monocentric | Dr. Andrea Rosi | Hôpitaux Universitaires de Genève |
Service de neuroradiologie diagnostique et interventionnelle, Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 24.07.2025 | |||||||
| 2025-01052 | Heartbeat Evoked Response as Objective Interoperative Self-consciousness Metric | non clinical, involving persons | monocentric | A | Pr Karl Schaller | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.09.2025 | ||||||
| 2025-01049 | Identification of genetic variants associated with lichen sclerosus | non clinical, involving persons | multicentric | A | Gudula Kirtschig | Medbase Frauenfeld |
Medbase Frauenfeld, Frauenfeld Leiter der Gyn-Zentren, Luzern und Cham, 6006 Luzern |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.10.2025 | yes | ||||
| 2025-01048 | C5751003 / An Open-Label, Randomized, Controlled Phase 3 Study of Sigvotatug Vedotin in Combination with Pembrolizumab Compared with Pembrolizumab Monotherapy as First-Line Treatment in Participants w More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Lorenz Bankel | Pfizer Inc. |
UniversitätsSpital Zürich, Zürich Inselspital Bern, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 12.08.2025 | |||
| 2025-01047 | "Economic and clinical burden of Uncoded Hyponatremia: A 10-Year Real-World Data Analysis of Prevalence, Costs, and Clinical Outcomes in a Swiss Tertiary Care Hospital" | personal data/biological material | monocentric | Dr. Wolfram Weinrebe | KSA |
Geriatric Trauma Center, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.07.2025 | |||||||
| 2025-01046 | Mesure du taux d’hème-oxygénase 1 dans des sérums de patients pédiatriques atteints de syndrome d’activation macrophagique | personal data/biological material | monocentric | Prof. Cem Gabay | Faculté de Médecine |
Faculté de Médecine, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 11.07.2025 | |||||||
| 2025-01043 | Validity and Reliability of Calf Raise Tests in Patients with Achilles Tendon Rupture and Lateral Ankle Sprain | clinical trial | other clinical trials | monocentric | A | Nicola Maffiuletti | Schulthess Klinik |
Schulthess Clinic, Zürich |
Kantonale Ethikkommission Zürich | 12.09.2025 | Study has ended | ||||
| 2025-01042 | Selexys DS - A retrospective clinical and radiological midterm outcome analysis of the MathysTM DS Evolu-tion system | personal data/biological material | monocentric | Prof. Dr. med. Martin Clauss | University Hospital |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.06.2025 | |||||||
| 2025-01041 | The FaibaGo Study – Long-Term Weight Reduction via Low-Threshold Intervention | clinical trial | other clinical trials | monocentric | A | Prof., MD, PhD Maria Luisa Balmer | Department of Biomedical Research, University of Bern |
Department of Biomedical Research, University of Bern, Bern |
Kantonale Ethikkommission Bern | 30.07.2025 | |||||
| 2025-01040 | The role of early postoperative procalcitonin levels in the prediction of complications and graft function after kidney transplantation | personal data/biological material | monocentric | PD Dr. med. Fabian Rössler | Department of Surgery and Transplantation |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 18.12.2025 | |||||||
| 2025-01039 | PSYCHE | non clinical, involving persons | monocentric | A | PhD Xavier MABIRE | UNIL - Institut Psychologie |
Université de Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.09.2025 | ||||||
| 2025-01038 | Establishment of new mouse intraductal (MIND) xenograft models and ex vivo assays for preclinical studies of breast cancer and predictive biomarker development | non clinical, involving persons | monocentric | A | Professor Cathrin Brisken | EPFL SV ISREC UPBRI |
ISREC EPFL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 04.11.2025 | ||||||
| 2025-01037 | Influence of the Slow Wave Sleep Modulation on Learning and Lexical-Semantic Integration of the New Words | non clinical, involving persons | monocentric | A | Professor Sophie Schwartz | University of Geneva (UNIGE) |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 12.09.2025 | ||||||
| 2025-01036 | Evaluating the Quality of Structured Data Extraction from Imaging Reports of Patients with Cancer using Locally Hosted Large Language Models. | personal data/biological material | monocentric | Johannes M. Schwenke | University Hospital Basel |
Klinische Epidemiologie, Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.05.2025 | |||||||
| 2025-01035 |
FI-CH: Firework-Related Injuries in Children in Switzerland – A 20-Year Analysis of Incidence, Severity, and Prevention |
personal data/biological material | monocentric | PD Dr. med. Sophie Böttcher | Kinderspital Zürich |
Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 25.07.2025 | |||||||
| 2025-01034 | LEMAN HOPE: Promoting well-being in children and adolescents in cancer remission through a sailing adventure | non clinical, involving persons | monocentric | A | Dre Jennifer Masset | Leman Hope Foundation |
Haute Ecole de Santé Vaud (HESAV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 12.08.2025 | yes | |||||
| 2025-01033 | Multiparametric MRI in the assessment of bladder cancer | personal data/biological material | multicentric | PD Dr. Andreas Hötker |
UniversitätsSpital Zürich, Zürich Inselspital Bern, Bern Luzerner Kantonsspital, Luzern HOCH Health Ostschweiz, St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 29.07.2025 | |||||||
| 2025-01032 | Évaluation de l’efficacité de l’entraînement à la marche assistée par robot sur la motricité globale et le bien-être des enfants en situation de handicap | personal data/biological material | monocentric | Marine Cacioppo | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaire de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.09.2025 | |||||||