| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-02145 |
Neuromuscular fatigue following competitive elite senior female soccer match-play. |
non clinical, involving persons | monocentric | A | Dr. phil. Nicola Maffiuletti | Schulthess Klinik |
HPL Schulthess Clinic, Zürich |
Kantonale Ethikkommission Zürich | 17.01.2023 | Study has ended | |||||
| 2022-02143 |
BOrrelia BUrgdorferi IN Children and Adolescents– a seroprevalence study (BOBUINCA) |
personal data/biological material | monocentric | Prof. Dr.med. /Ulrich/Heininger | University Children's Hospital Basel |
University Children's Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.02.2023 | |||||||
| 2022-02142 | Serum dioxin concentrations in the Lausanne population – A pilot population-based survey | non clinical, involving persons | monocentric | A | Pr David Vernez | Unisanté - DSTE |
Unisanté, University of Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.03.2023 | ||||||
| 2022-02141 | Long-term course of symptomatic ambulatory COVID-19 patients treated with enoxaparin or no anticoagulation: long-term follow-up analysis of the OVID randomized trial | non clinical, involving persons | multicentric | A | PD Dr. Ph.D Stefano Barco | Universitätsspital Zürich |
Klinik für Angiologie, Zürich Insel Gruppe AG, Bern Universitätsspital Basel, Basel Universitätsspital Genf, Genf Ente Ospidaliera Cantonal Bellinzona, Bellinzona Clinica Luganese Moncucco, Lugano |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino | 10.03.2023 | Study has ended | ||||
| 2022-02140 | CHILD-C : Facteurs prédictifs de mortalité chez les patients avec une cirrhose hépatique Child C hospitalisés aux soins intensifs (CHILD-C) : Expérience Lausannoise sur la période 2011-2021 | personal data/biological material | monocentric | Pr Lucas Liaudet |
CHUV-SMIA, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 15.12.2022 | ||||||||
| 2022-02139 | Conservative therapy of great tuberosity fracture after (anterior) shoulder dislocation leads to satisfying clinical and radiological results compared to a matched control group | personal data/biological material | monocentric | Dr.med. Florian Grubhofer | Universitätsklinik Balgrist |
Universitätsklink Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 06.01.2023 | |||||||
| 2022-02138 | Multicentre comparison of interictal high-frequency oscillations as a predictor of seizure freedom | personal data/biological material | monocentric | Prof. Dr. techn. Johannes Sarnthein | Universitätsspital Zürich |
UniversitätsSpital, Zürich |
Kantonale Ethikkommission Zürich | 06.01.2023 | |||||||
| 2022-02137 | Subtypes of Modic type 2 changes and their association with low back pain | personal data/biological material | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 06.01.2023 | |||||||
| 2022-02136 | M23-696: A Phase 3b/4 Randomized, Open-label, Efficacy Assessor Blinded Study, Comparing the Safety and Assessor Blinded Efficacy of Upadacitinib to Dupilumab in Subjects with Moderate to Severe Atopi More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Ieva Saulite | AbbVie Inc. |
Kantonsspital St. Gallen, St. Gallen Inselspital, Universitätsklinik für Dermatologie, Bern Universitätsspital Basel, Dermatologie, Basel Universitätsspital Zürich, Dermatologische Klinik, Zürich |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 09.03.2023 | yes | ||
| 2022-02134 |
Risk factors for the use of a primary higher-constrained total knee arthroplasty – a retrospective single-center analysis |
personal data/biological material | monocentric | Prof. Dr. med. Sandro Fucentese | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 22.12.2022 | |||||||
| 2022-02133 | Benefit-to-risk balance of coronary angiography in the critically ill | personal data/biological material | monocentric | Dr Hamid Merdji | Basel University Hospital |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.02.2023 | |||||||
| 2022-02132 | Monocentric retrospective study of 341 children with Appendectomy: How frequent is oxyuriasis? | personal data/biological material | monocentric | Prof. med. Henrik Köhler | Kinderspital am Kantonsspital Aarau |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.03.2023 | |||||||
| 2022-02131 | 19767_A multicenter, international, randomized, active comparator-controlled, double-blind, doubledummy, parallel-group, 2-arm, Phase 3 study to compare the efficacy and safety of the oral FXIa inhibi More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Angelo Auricchio | Bayer AG |
Istituto Cardiocentro Ticino, Lugano lnselspital Bern, Bern Universitätsspital Basel, Basel Kantonspital Aarau AG, Aarau Kantonsspital Baden AG, Baden Kantonsspital St. Gallen, St. Gallen HFR Hôpital More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 13.02.2023 | Study has ended | ||
| 2022-02130 | CAIN457C22301 - A randomized, parallel-group, double-blind, placebo-controlled, multicenter Phase III trial to evaluate efficacy and safety of secukinumab administered subcutaneously versus placebo, i More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Andrea Rubbert-Roth | Novartis Pharma Schweiz AG |
Kantonsspital St. Gallen, St. Gallen Universitätsspital, Basel HFR Fribourg – Hôpital Cantonal, Fribourg |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.02.2023 | |||
| 2022-02129 | A two-part, randomized, placebo controlled, double blind, multicenter, Phase 3 study to evaluate the efficacy and safety of linerixibat for the treatment of cholestatic pruritus in participants with p More ... | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. med. Benedetta Terziroli Beretta-Piccoli | GlaxoSmithKline Research & Development Limited |
Epatocentro Ticino, Lugano |
Comitato etico cantonale Ticino | 27.02.2023 | Study has ended | |||
| 2022-02128 | Post Intensive Care Syndrome in Swiss Pediatric survivors and their Families [PICSS-PF]: A Multi-center Longitudinal Observational Study | non clinical, involving persons | multicentric | A | Dr. Zahra Rahmaty | IUFRS/University Hospital of Lausanne |
IUFRS, CHUV, Lausanne Universitätsklinik für Kinderheilkunde, Bern Kinderspital - Luzerner Kantonsspital, Luzern Universitätskinderklinik beider Basel (UKBB), Basel Hôpitaux Universitaires de Genève ( More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 25.04.2023 | yes | ||||
| 2022-02127 | An exploratory study on autoantibodies in cancer patients – IOSI-IRB-001 study | personal data/biological material | monocentric | Dr. med. Ilaria Colombo | Istituto Oncologico della Svizzera Italiana |
Istituto Oncologico della Svizzera Italiana, Bellinzona |
Comitato etico cantonale Ticino | 25.01.2023 | |||||||
| 2022-02126 | An Open-label, Dose Escalation, Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of TAK-676 as a Single Agent and in Combination With Pembrolizumab in Adult More ... | clinical trial | drugs | phase 1 | multicentric | C | Prof. Dr. med. Martin Berger | Takeda Development Center Americas, Inc. (TDC Americas) |
Universitätsklinik für Medizinische Onkologie, Inselspital, Bern Hôpitaux Universitaires de Genève, Geneva Kantonsspital St.Gallen, Klinik für med. Onkologie & Hämatologie, St.Gallen Centre Hospitalie More ... |
Kantonale Ethikkommission Bern | Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.07.2023 | |||
| 2022-02125 | Intraoperative neurophysiological markers to predict outcome in hemifacial spasm | personal data/biological material | monocentric | Prof. Dr. Med. Kathleen Seidel | Department of Neurosurgery, Inselspital |
Department of Neurosurgery, University Hospital Bern, Inselspital, Bern |
Kantonale Ethikkommission Bern | 06.04.2023 | Study has ended | ||||||
| 2022-02124 | Sleep disordered breathing in children and adolescents with obesity | non clinical, involving persons | monocentric | A | Dre Virginie Bayon | CHUV - CIRS - BH 06 |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.01.2023 | yes | |||||