BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2023-01744 | Masterarbeit zur Korrelation vom Peritoneal Cancer Index (PCI) Score nach neoadjuvanter Chemotherapie mit dem progressionsfreien Überleben (PFS) für Patientinnen mit fortgeschrittenem Ovarialkarzinom | personal data/biological material | monocentric | Dr. med. Heike Passmann-Kegel |
Stadtspital Zürich Triemli, 8063 Zürich |
Kantonale Ethikkommission Zürich | 12.01.2024 | ||||||||
2023-01742 | Primary lymphovenous anastomosis after extended soft tissue resection in the medial thigh for reduction of lymphocele and lymphedema | personal data/biological material | monocentric | Prof Dr med Nicole Lindenblatt | Klinik für Plastische Chirurgie USZ |
Klinik für Plastische Chirurgie Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 14.11.2023 | Study has ended | ||||||
2023-01741 | Treatment recommendations, adherence and outcome of lymphoma patients discussed at a multi-disciplinary lymphoma board - a pilot for continuous clinical service evaluation and benchmarking in routine More ... | personal data/biological material | monocentric | PD Dr Benjamin Kasenda | Medizinische Onkologie |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.10.2023 | |||||||
2023-01740 | Développement d’un outil de prédiction des crises et effet du sevrage thérapeutique dans des épilepsies pharmacorésistances | non clinical, involving persons | monocentric | A | Dr Jérôme de Massias de Bonne | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 15.11.2023 | ||||||
2023-01739 | Facilitating Artificial Intelligence-based Decision-Making in Spondylodiscitis Patients | personal data/biological material | multicentric | Dr. Stefan Motov | Kantonsspital St. Gallen |
Kantonsspital St. Gallen, Neurochirurgie, St. Gallen Department of Orthopaedics and Traumatology, Inselspital Bern, Prof. Dr. Tannast, Bern Neurosurgery, Aarau |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 29.09.2023 | ||||||
2023-01738 | MarkEpi: Seizure biomarkers after non-epileptic events | non clinical, involving persons | monocentric | A | Dr Isabelle Beuchat | CHUV - BH07 - Neurologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.11.2023 | ||||||
2023-01737 | Pharmacokinetics of Didehydro-LSD (DDH-LSD) compared with LSD | clinical trial | other clinical trials | monocentric | B | Prof. Dr. med. Matthias Liechti | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.11.2023 | |||||
2023-01735 |
A Multicenter, Adaptive, Randomized, Controlled Trial Platform To Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections; Appendix E-1: Shiono More ... |
clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Huldrych Günthard | Regents of the University of Minnesota |
University Hospital Zurich, Zurich Universitätsspital Basel, Basel |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.12.2023 | |||
2023-01734 | Anterior Longitudinal Ligament (ALL) reconstruction improves biomechanical stability and controlled range of motion after cervical fusion or disc arthroplasty | deceased persons | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 17.11.2023 | |||||||
2023-01732 | Interreader-Variabilität in der Beurteilung von Kalziumablagerungen der Koronararterien mittels Low-dose-Computertomographie | personal data/biological material | monocentric | PD Dr. med. Tobias Gassenmaier |
Luzerner Kantontsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.09.2023 | ||||||||
2023-01731 |
TYK2 inhibition in paradoxical psoriasis (TYPP) A randomized, double-blind, placebo-controlled multi-center study evaluating the effect of Deucravacitinib on severity of psoriasis in patients with pa More ... |
clinical trial | drugs | phase 2 | monocentric | C | Prof Curdin Conrad | Dermatologie CHUV |
Dermatologie CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.04.2024 | ||||
2023-01730 | iCHECK: Impact of clonal haematopoiesis on the efficacy of checkpoint inhibition: A retrospective single center analysis. | personal data/biological material | monocentric | Dr. med. Dr. sc. nat. Jeremy Deuel | Universitätsspital Zürich |
Universitätsspital, Zürich |
Kantonale Ethikkommission Zürich | 19.12.2023 | |||||||
2023-01727 | International Real-World Study of MET Overexpression in Patients with Non-Small Cell Lung Cancer (METRIX study) | personal data/biological material | multicentric | PD Dr. med. Spasenija Savic Prince | AbbVie AG |
Universitätsspital Basel, Basel Universitätsspital Zürich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 24.10.2023 | ||||||
2023-01726 | COMPANION DIAGNOSTICS: Measurement of the GSM Phase 1 trial (BP44161) with CSF and blood based biomarker immunoassays - RD006619 | personal data/biological material | monocentric | Ms Geraldine Peeters | Roche Diagnostics GmbH |
Labcorp, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.10.2023 | |||||||
2023-01724 | Subsartorial Saphenous Nerve Block (SSNB) versus Femoral Nerve Block (FNB) in primary Total Knee Arthroplasty (TKA) combined with Infiltration between Popliteal Artery and Capsule of the Knee (IPACK) More ... | clinical trial | other clinical trials | monocentric | A | Dr. med. Judith Bering | Klinik für Orthopädie und Unfallchirurgie |
Klinik für Orthopädie und Unfallchirurgie Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.10.2023 | |||||
2023-01723 | Gibt es einen Zusammenhang zwischen der Dosis, Wirksamkeit, Toxizität und fettfreien Körpermasse von Krebspatienten, die mit Tyrosinkinaseinhibitoren behandelt werden? | personal data/biological material | monocentric | Dr Berna Özdemir | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 24.10.2023 | |||||||
2023-01721 |
AMBRA: Assessment of Microstructural Brain Alterations Assessment of myelin content and tissue microstructure in multiple sclerosis: a repeated MRI study |
non clinical, involving persons | monocentric | B | Prof.Dr.med.Dr.phil. Cristina Granziera | Research Center for Clinical Neuroimmunology and Neuroscience RC2NB |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.12.2023 | ||||||
2023-01719 | Bland portal vein thrombosis in patients with hepatocellular carcinoma: characteristics, clinical features and response to anticoagulation | personal data/biological material | monocentric | Prof. Annalisa Berzigotti | Insel Gruppe AG |
Insel Gruppe AG, Bern |
Kantonale Ethikkommission Bern | 10.11.2023 | Study has ended | ||||||
2023-01718 | Physiological activation measured by EEG during physical effort | non clinical, involving persons | monocentric | A | Petra Susan Hüppi | Hôpitaux Universitaires de Genève |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 11.12.2023 | yes | |||||
2023-01717 | M23-698: A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Efficacy and Safety of Upadacitinib in Adult and Adolescent Subjects with Moderate to Severe Hidradenitis Suppurativa More ... | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med. Julia-Tatjana Maul | AbbVie Inc. |
USZ, Dermatologische Klinik, Zürich Universitätsklinik für Dermatologie, Insel Bern, Bern HUG,Dermatologie et Vénéréologie, Genève KSSG, Klinik für Dermatologie, St.Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) | 12.12.2023 | yes | ||