| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-01716 | Characteristics and treatment of patients with Precursor B Acute Lymphoblastic Leukemia and Li-Fraumeni Syndrome – a retrospective study. | personal data/biological material | monocentric | PD Dr Med Francesco Ceppi | CHUV - BH11-969 |
CHUV Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.09.2021 | |||||||
| 2021-01715 | “Drug survival" des Medikaments Omalizumab in einer Langzeitkohorte von Patienten mit chronisch spontaner Urtikaria (CSU). | personal data/biological material | monocentric | Prof. Dr. med. Peter Schmid-Grendelmeier | Universitätsspital Zürich, Dpt. of Dermatology |
USZ, Zurich |
Kantonale Ethikkommission Zürich | 05.10.2021 | |||||||
| 2021-01714 | Exploring the phenotypic capacity of transcription factors in human embryonic stem cells at the single cell level | personal data/biological material | monocentric | Prof David Suter | EPFL SV IBI-SV |
Ecole Polytechnique Federale de Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 31.08.2021 | |||||||
| 2021-01713 | Implementation of video-observed therapy (VOT) as a new mode of directly observed therapy (DOT) in the follow-up of treatment for active tuberculosis: a proof of concept study | clinical trial | other clinical trials | monocentric | A | Professor Jean-Paul Janssens | Service de Pneumologie |
Geneva University Hospitals, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 24.03.2022 | |||||
| 2021-01712 | Evaluating a smartphone-based digital patient portal to facilitate perioperative patient management and determine patient specific outcome measures in spine surgery | personal data/biological material | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 31.08.2021 | |||||||
| 2021-01711 | Thrombocytopenia after aortic valve replacement: a comparison between the sutureless Perceval, the rapid deployment Intuity and the transcatheter Sapien bioprosthesis | personal data/biological material | monocentric | Prof. Dr. med. Dr. h. c. Omer Dzemali |
Stadtspital Triemli Zürich, Zürich |
Kantonale Ethikkommission Zürich | 24.09.2021 | ||||||||
| 2021-01709 | Inflammatory Neuropathy Consortium Base (INCbase). A prospective international CIDP registry. | non clinical, involving persons | multicentric | A | Dr.med. Paolo Ripellino | Neurocenter of Southern Switzerland |
Neurocenter of Southern Switzerland, Lugano Inselspital, Bern Universitaetspital Basel, Basel HUG, Geneva Kantonsspital St. Gallen, St. Gallen HFR Fribourg - Hôpital cantonal, Fribourg CHUV, Lausanne |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... | 31.08.2021 | |||||
| 2021-01708 | A PHASE IV MULTICENTER, OPEN-LABEL STUDY EVALUATING B CELL LEVELS IN INFANTS POTENTIALLY EXPOSED TO OCRELIZUMAB DURING PREGNANCY – THE MINORE STUDY | non clinical, involving persons | multicentric | B | Prof. Dr. med. Tobias Derfuss | F. Hoffmann-La Roche Ltd |
Universitätsspital Basel, Basel Universitätsklinik für Neurologie Inselspital, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 14.12.2021 | yes | ||||
| 2021-01707 | Assessment of psychological Risk factors in Patients undergoing cardiac surgery | personal data/biological material | monocentric | Prof. Dr. Omer Dzemali |
Stadtspital Zürich Triemli, Zürich |
Kantonale Ethikkommission Zürich | 05.10.2021 | ||||||||
| 2021-01706 | Evaluation of the Effectiveness of Add-on Home Treatment to Familiy Based Therapy in Adoloescent Anorexia Nervosa. A randomised controlled clinical trial. | clinical trial | other clinical trials | monocentric | A | M.Sc. Nicole Flütsch | Psychiatrische Universitätsklinik Zürich Klinik für Kinder- und Jugendpsychiatrie und Psychotherapie |
Psychiatrische Universitätsklinik Klilni für Kinder- und Jugendpsychiatire und Psychotherapie, Zürich |
Kantonale Ethikkommission Zürich | 26.11.2021 | yes | ||||
| 2021-01705 | A multicenter, prospective observational RWE study to assess Patient-reported wellbeing using tildrakizumab in a live setting – POSITIVE Study | non clinical, involving persons | multicentric | A | Prof. MD PhD Alexander Navarini | ALMIRALL S.A. |
Universitätsspital Basel - Dermatologische Klinik, Basel Universitätsklinik für Dermatologie, Inselspital, Bern Dermatology & Skin Care Clinic, Buochs Kantonsspital St. Gallen - Klinik für Dermatologi More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 07.01.2022 | |||||
| 2021-01704 | EXPANSE Urban Labs | non clinical, involving persons | monocentric | A | Prof. Nicole Probst-Hensch | Swiss Tropical and Public Health Institute |
Swiss Tropical and Public Health Institute, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.01.2022 | ||||||
| 2021-01703 | SERENA-6: A Phase III, Double-blind, Randomised Study to Assess Switching to AZD9833 (a Next Generation, Oral SERD) + CDK4/6 Inhibitor (Palbociclib or Abemaciclib) vs Continuing Aromatase Inhibitor (L More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Manuela Rabaglio | AstraZeneca AB |
Inselspital, Universitätsspital Bern, Bern Kantonsspital Winterthur, Winterthur Kantonsspital Graubünden, Chur |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 28.07.2022 | |||
| 2021-01702 | Post-traumatic disorders, substance use and resilience among refugees in Geneva: an observational cohort study in a primary care setting. RE-START (REfugees, STress, Addictions, Resilience and Trauma) More ... | non clinical, involving persons | monocentric | A | Ms.Dr.Sophie Durieux-Paillard | Programme Sante Migrants, Service de Médecine de Premier Recours, Hôpitaux Universitaires Genève |
Programme Sante Migrants, Service de Médecine de Premier Recours, Hôpitaux Universitaire Genève, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.10.2021 | ||||||
| 2021-01701 | Utility of the Adaptive Cognitive Evaluation Explorer (ACE-Explorer) as a Screening Instrument in Memory Clinic patients – ACE-MEM. | non clinical, involving persons | multicentric | A | Prof. Arseny Sokolov | CHUV - Neurosciences cliniques |
CHUV, Lausanne Universitätsklinik für Alterspsychiatrie und Psychotherapie (UAP), Murtenstrasse 21, 3008 Bern |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern | 25.11.2021 | |||||
| 2021-01700 | Motor Performance During ExerCube Training | non clinical, involving persons | monocentric | A | Dr. Eveline Graf | ZHAW |
ZHAW, Winterthur |
Kantonale Ethikkommission Zürich | 10.09.2021 | Study has ended | |||||
| 2021-01698 | PROGNOSTIC OF DYSFUNCTIONAL BREATHING IN LONG COVID: A FOLLOW UP STUDY. | non clinical, involving persons | multicentric | A | Pr Pierre-Olivier Bridevaux | CHVR -Hôpital de Sion |
Centre Hospitalier du Valais Romand, Sion Hôpital riviera-chablais, Rennaz |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.09.2021 | yes | ||||
| 2021-01697 | Quantification de la dépendance par la mesure de l’information mutuelle, entre l’expression de la protéine HuR et celle de marqueurs de différentiation mélanocytaire et d’activation de la voie des MAP More ... | personal data/biological material | monocentric | M.D-Ph.D/Rastine/Merat |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 16.09.2021 | ||||||||
| 2021-01696 | Computer-aided Detection and Diagnosis of Musculoskeletal Abnormalities of the Lumbar Spine from MRI Scans | personal data/biological material | multicentric | PD Dr. med. Sabine Sartoretti | Balzano Informatik AG |
Kantonsspital Winterthur, Zürich Medizinisch Radiologisches Institut, 8001 Zürich RNR Radiologie und Neuroradiologie am Glattzentrum, 8304 Wallisellen |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 09.11.2021 | ||||||
| 2021-01694 | Novel negative pressure wound closure technique with partial delayed wound closure in abdominal high-risk incisions to reduce SSI rates: a retrospective matched case control study | non clinical, involving persons | monocentric | A | Prof. Dr. med. Beat Schnüriger | Leitender Arzt Viszerale Chirurgie |
Klinik für Viszerale Chirurgie und Medizin Inselspital – Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 01.11.2021 | ||||||