| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-01029 | Value of fetal Doppler surveillance in intrahepatic cholestasis of pregnancy | personal data/biological material | monocentric | Prof. Manegold-Brauer Gwendolin | Universitätsspital Basel |
Universitatsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.05.2025 | |||||||
| 2025-01028 | Deciphering the structural and functional connectivity of the anterior insula in the proneness to ecstatic experience in patients with epilepsy | non clinical, involving persons | monocentric | A | Dr Fabienne Picard | University Hospitals of Geneva |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.07.2025 | ||||||
| 2025-01027 | Identification of subphenotypes in critically ill patients with sepsis and septic shock (PhenSiS) | personal data/biological material | monocentric | Prof. Dr. med. Sascha David | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 13.03.2026 | |||||||
| 2025-01026 | Enhancing Emotion Regulation in Youth through Neurofeedback Training: An Adjunctive Approach to Standard In-Patient Multimodal Psychotherapy - a Pilot Study | clinical trial | other clinical trials | monocentric | A | Dr. med. Patrick Köck | Klinik Barmelweid AG |
Klinik Barmelweid, 5017 Barmelweid |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.07.2025 | |||||
| 2025-01025 | Autoimmun- und Bindegewebserkrankungen als Risikofaktoren für pelvine Neuropathien durch vaskuläres Entrapment - eine retrospektive Beobachtungsstudie | personal data/biological material | monocentric | Prof. Prof. DK Prof. hc (China) Dr. med. | Possover International Medical Center AG |
Possover International Medical Center AG, Zürich |
Kantonale Ethikkommission Zürich | 18.07.2025 | |||||||
| 2025-01024 |
Hidden cognitive impact? Neuropsychological assessment in patients with conservatively managed meningiomas |
non clinical, involving persons | monocentric | A | Prof. Dr. Jehuda Soleman | Universität Basel Direktion Finanzen |
Neurochirurgie Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.06.2025 | ||||||
| 2025-01023 | Autologous serum eye drops for the treatment of ocular surface diseases: a retrospective real-life study | personal data/biological material | monocentric | Dr. Martina Kropp | HUG |
HUG and UNIGE, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 16.07.2025 | |||||||
| 2025-01022 | The role of IL-18 in stimulating anti-tumoral responses in an ex-vivo model of human tumor biopsy samples | personal data/biological material | monocentric | Cem Gabay | Faculty of Medicine University of Geneva |
Faculty of Medicine University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.09.2025 | |||||||
| 2025-01021 | Comparison of a new cooling concept for operations in hypothermic circulatory arrest with a previous cohort based on postoperatively measured kidney and liver laboratory parameters. | personal data/biological material | monocentric | Prof. Oliver Reuthebuch |
Clinic for Cardio-Vascular Surgery, University Hospital Basel, Basel, 4031 Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.04.2026 | ||||||||
| 2025-01020 | Clinical and radiolocigal mid-term results of patient specific implants (PSI) in unicompartmental knee arthroplasties. Subanalysis of PSI medial cementless unicompartmental knee arthroplasty, outcomes More ... | personal data/biological material | monocentric | Prof. Dr. med. Näder Helmy | Klinik für Orthopädie und Traumatologie, Bürgerspital Solothurn |
Klinik für Orthopädie und Traumatologie, Bürgerspital Solothurn, Solothurn |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.02.2026 | |||||||
| 2025-01019 | Trainieren und externe Validierung von Algorithmen des maschinellen Lernens für neurochirurgische Probleme | personal data/biological material | monocentric | Prof. Dr. med. Ulf Schneider | LUKS |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.06.2025 | |||||||
| 2025-01017 | Long Term clinical and radiological outcomes of primary reverse total shoulder arthroplasty at a minimum follow-up of 15 years | personal data/biological material | monocentric | Prof. Dr. med Karl Wieser | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, 8008 Zürich |
Kantonale Ethikkommission Zürich | 23.09.2025 | |||||||
| 2025-01016 | Lumbar spinal process deformation during physiological loading - a retrospective radiographic analysis | personal data/biological material | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 08.07.2025 | |||||||
| 2025-01015 | Endoscopic Fenestration in the management of supra-tentorial intra and para-ventricular cysts: A multicenter study | personal data/biological material | monocentric | Prof. Dr. med. Jehuda Soleman | Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center |
Neurosurgery and Pediatric Neurosurgery, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.08.2025 | Study has ended | ||||||
| 2025-01014 | Molecular Analysis of Stimulation Associated Reinforcement in Neuroplasticity (MASARIN) | personal data/biological material | monocentric | Prof. Maxime Baud | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 30.07.2025 | |||||||
| 2025-01013 | A two-year prospective, observational study of Wegovy® in real-world clinical practice (PILLAR) | non clinical, involving persons | multicentric | A | Prof. Dr. Bernd Schultes | Novo Nordisk A/S |
Stoffwechselzentrum St. Gallen, St. Gallen Kantonsspital, Luzern |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.07.2025 | |||||
| 2025-01012 | Impact of Pre-Transplant Cardiovascular Disease on Outcomes in Lung Transplant Recipients: A Retrospective Cohort Study | personal data/biological material | monocentric | PhD.Dr.med. René Hage | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 22.08.2025 | |||||||
| 2025-01011 | Etat des lieux de la prescription de médicaments immunosuppresseurs dans un hôpital gériatrique | personal data/biological material | monocentric | Dr Kuntheavy Ing Lorenzini | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 02.09.2025 | |||||||
| 2025-01010 | Dying on venovenous and venoarterial extracoroporeal membrane oxygenation – a retrospective analysis of cause of death, medical decision-making at the end of life, role of treatment limitations and pa More ... | personal data/biological material | monocentric | Prof. Dr. med. Sascha David | Klinik und Poliklinik für Innere Medizin |
Institut für Intensivmedizin, Zürich |
Kantonale Ethikkommission Zürich | 26.09.2025 | |||||||
| 2025-01009 | Efficacy of sequential use of antibody-drug conjugates targeting Topoisomerase-1 (Trastuzumab Deruxtecan then Sacituzumab Govitecan or vice versa) in patients with locally advanced or metastatic HER2- More ... | personal data/biological material | monocentric | PD Dr. med. Khalil ZAMAN | Medical Oncology Department IUCT-Oncopole |
Lausanne University Hospital CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.07.2025 | |||||||