| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-D0040 | DreaMS - Development of Digital Biomarkers in Multiple Sclerosis - Validation Study 1 | clinical trial | medical devices | multicentric | C2 | PD Dr. med. Johannes Lorscheider | Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB) |
University Hospital Basel, Switzerland, Basel Centro Sclerosi Multipla, Ospedale Regionale di Lugano, Via Tesserete 46 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Comitato etico cantonale Ticino | 18.11.2021 | ||||
| 2021-D0039 | Effectiveness of a powered exoskeleton combined with functional electric stimulation for patients with chronic spinal cord injury: a randomized controlled trial | clinical trial | medical devices | monocentric | A1 | Dr. sc. ETH Mario Widmer | Schweizer Paraplegiker-Zentrum |
Schweizer Paraplegiker-Zentrum, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.10.2021 | |||||
| 2021-D0038 | Investigation of Retinal Pathology in Eye Diseases using High Resolution Spectralis Optical Coherence Tomography (High-Res-OCT) | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Martin Zinkernagel | University Clinic for Ophthalmology |
University hospital of Bern, Inselspital, Department of Ophthalmology, Bern |
Kantonale Ethikkommission Bern | 13.10.2021 | |||||
| 2021-D0037 |
Evaluation of three different filling materials for the atraumatic restorative treatment (ART) of root caries in older adults: A single-blind, randomized, controlled trial |
clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. dent. Murali Srinivasan | University of Zurich, Center of Dental Medicine |
Universität Zürich, ZZM/ABS, Zürich |
Kantonale Ethikkommission Zürich | 17.01.2023 | |||||
| 2021-D0036 | Zinc Paste Bandage vs Betnovate vs Zinc Paste Bandage with Betnovate vs Null Treatment in Chronic Prurigo: Randomized Controlled Half side Crossover Trial | clinical trial | medical devices | monocentric | A1 | Prof. Jürg Hafner | UniversitätsSpital Zürich |
UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 05.11.2021 | |||||
| 2021-D0035 |
PiCSO-AMI-V Inferior STEMI A randomized, controlled, pilot study to evaluate safety and feasibility of Pressure-controlled intermittent Coronary Sinus Occlusion (PiCSO) therapy in patients with exten More ... |
clinical trial | medical devices | multicentric | C1 | Prof. Dr. Marco Valgimigli | Miracor Medical SA |
Istituto Cardiocentro Ticino, Lugano Universitätsklinik für Kardiologie, Inselspital Bern, Bern |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Bern | 30.12.2021 | Study has ended | |||
| 2021-D0034 | Glucosafe 2 - A new Tool for Nutritional Management and Insulin-therapy in the Intensive Care Unit: Randomized Controlled Study | clinical trial | medical devices | monocentric | C2 | Dr. Claudia-Paula Heidegger | Geneva University Hospitals |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.12.2021 | |||||
| 2021-D0032 | Stereotactic MRI-guided radiation therapy for Localized prostatE cancer (SMILE) | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Nicolaus Andratschke | Universitätsklinikum Heidelberg |
UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 01.02.2022 | |||||
| 2021-D0031 |
Unterarm-Combicast versus Oberarm-Combicast bei gelenksnahen distalen (Salter Harris I/II) Radius- und Vorderarmfrakturen im Kindesalter |
clinical trial | medical devices | monocentric | A1 | Dr.med Camilla Lavagno | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 26.10.2021 | yes | ||||
| 2021-D0030 | Evaluation of the clinical benefit of a transmitter for Contralateral Routing of Signals (CROS) | clinical trial | medical devices | monocentric | C2 | Bernhard Buschle | Sonova AG |
Sonova AG, Stäfa |
Kantonale Ethikkommission Zürich | 12.10.2021 | Study has ended | ||||
| 2021-D0029 | SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med Thomas Pilgrim | Medtronic Bakken Research Center B.V. |
Insel Gruppe AG, Inselspital, Bern |
Kantonale Ethikkommission Bern | 23.11.2021 | |||||
| 2021-D0027 |
YpsoPump occlusion detection algorithm: Collection of real-world data for in-silico evaluation of a new software algorithm to refine occlusion detection in subjects with type 1 diabetes using contin More ... |
clinical trial | medical devices | monocentric | A1 | Prof. med. Markus Laimer | YPSOMED AG |
UDEM, Bern |
Kantonale Ethikkommission Bern | 21.12.2021 | Study has ended | ||||
| 2021-D0026 |
Distal Evaluation of Functional performance with Intravascular sensors to assess the Narrowing Effect: Guided Physiologic Stenting (DEFINE GPS) |
clinical trial | medical devices | monocentric | A2 | Dr. Juan Fernando Iglesias | Philips Image Guided Therapy Devices |
Hôpitaux universitaires de Genève, Cardiology Unit, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.02.2022 | |||||
| 2021-D0025 | Epidural Electrical Stimulation to restore hemodynamic stability and trunk control in people with spinal cord injury. | clinical trial | medical devices | monocentric | C2 | Prof. Dr Jocelyne Bloch | Ecole Polytechnique Federale de Lausanne (EPFL) |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 29.11.2021 | |||||
| 2021-D0024 | CorPath GRX Neuro Study Protocol: An Evaluation of Effectiveness and Safety of the CorPath® GRX System in Endovascular Embolization Procedures of Cerebral Aneurysms | clinical trial | medical devices | monocentric | A1 | PD Dr. med. Pasquale Mordasini | Corindus, Inc. (A Siemens Healthineers Company) |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 08.11.2021 | Study has ended | ||||
| 2021-D0023 | GR40549: A MULTICENTER, OPEN-LABEL EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY AND TOLERABILITY OF THE PORT DELIVERY SYSTEM WITH RANIBIZUMAB IN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGEN More ... | clinical trial | combination drugs/devices | multicentric | C2 | Prof. Dr. med. Matthias Becker | Roche Pharma (Schweiz) AG |
Triemlispital, Zürich INSELSPITAL, Universitätsklinik für Augenheilkunde, Bern Vista Klinik Binningen, Hauptstrasse 55 Augenklinik - Universitaetsspital Basel, Mittlere Str. 55 Fondation Asile Des Ave More ... |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.11.2021 | ||||
| 2021-D0022 | LUNAR: Pivotal, randomized, open-label study of Tumor Treating Fields (TTFields) concurrent with standard of care therapies for treatment of stage 4 non-small cell lung cancer (NSCLC) following platin More ... | clinical trial | medical devices | monocentric | C1 | Prof. Dr. med. Miklos Pless | Novocure GmbH |
Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 16.11.2021 | |||||
| 2021-D0021 | Prospective randomized controlled trial in patients with early to mid-stage medial knee osteoarthritis comparing clinical and biomechanical outcomes of foot deformity correcting insoles and lateral we More ... | clinical trial | medical devices | monocentric | A1 | Prof. Dr. Dr. med. Frank Klenke | Inselspital, Bern University Hospital |
Inselspital, Bern University Hospital, Bern |
Kantonale Ethikkommission Bern | 15.11.2021 | |||||
| 2021-D0020 | Augmented reality enhanced ultrasound-guided versus standard ultrasound or fluoroscopic injections | clinical trial | medical devices | monocentric | A1 | PD Dr. med. Nadja Farshad | Universitätsklinik Balgrist |
Balgrist University Hospital, Zürich |
Kantonale Ethikkommission Zürich | 18.03.2022 | |||||
| 2021-D0018 | Measuring the pharmacodynamics on cortical excitability using transcranial magnetic stimulations | clinical trial | medical devices | monocentric | A1 | Dr. Med. Maxime Baud | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 10.11.2021 | |||||