BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2025-01270 Effects of ziltivekimab versus placebo on coronary atherosclerosis in patients
with acute myocardial infarction. A serial, multivessel, intravascular ultrasound, near-infrared spectroscopy and optica More ... 		clinical trial drugs phase 3 multicentric C Prof Dr. Dr Lorenz Räber European Cardiovascular Research Institute ECRI-16 Inselspital, Universitätsspital Bern, 3010 Bern
Universitätsspital Basel, Basel
Kantonsspital Luzern, Luzern
Hôpitaux Universitaires Genève (HUG), Genf
UniversitätsSpital Zürich, 8091 Zürich 		Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) 17.11.2025
2025-01269 Quality Analysis of Automated Geographic Atrophy Detection on OCT Images Using a Locally Deployed AI Algorithm personal data/biological material monocentric PhD Dr. med. habil. Gábor Márk Somfai Stadtspital Zürich Augenklinik Stadtspital Zürich Augenklinik, Zürich
 		Kantonale Ethikkommission Zürich 26.09.2025
2025-01268 Evaluation von Low-Pass-Whole-Genome-Sequencing im Vergleich zur Microarray-
Diagnostik hinsichtlich der Detektion von Kopienzahlvarianten und Homozygotieläufen 		personal data/biological material monocentric Anita Rauch University of Zurich Universität Zürich, Schlieren
 		Kantonale Ethikkommission Zürich 17.10.2025
2025-01267 Validation and examination of the Test-Retest-Reliability of the German version of the Wheelchair Users Shoulder Pain Index (WUSPI) non clinical, involving persons monocentric A Dr Wiebe de Vries Swiss Paraplegic Research Swiss Paraplegic Research, Nottwil
 		Ethikkommission Nordwest- und Zentralschweiz EKNZ 07.07.2025
2025-01266 Fighting Addictions, improving Lives through COmprehensive drug rehabilitation with music (FALCO): clinical trial other clinical trials monocentric A PD. Dr. Marcus Herdener Psychiatrische Universitätsklinik, Experimentelle Pharmakopsychologie und Psychologische Suchtforschung Erwachsenenpsychiatrie und Psychotherapie Psychiatrische Universitätsklinik Zürich, Zentrum für Abhängigkeitserkrankungen, 8007 Zürich
 		Kantonale Ethikkommission Zürich 05.12.2025
2025-01265 Serum proteome of living strangulation victims non clinical, involving persons multicentric A Dr med. Claudia CASTIGLIONI Centre universitaire romand de médecine légale Centre universitaire romand de médecine légale, Lausanne
Centre universitaire romand de médecine légale, Genève 		Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Commission Cantonale d'éthique de la recherche Genève (CCER) 24.03.2026
2025-01264 A Phase 1, Two-Part, Multicenter, Open-Label First in Human Study of anti-GD2 Antibody Drug Conjugate M3554 in Participants with Advanced Solid Tumors clinical trial drugs phase 1 monocentric C Prof. Dr. med. Michael Weller Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany, Frankfurter Str. 250, 64293 Darmstadt, Germany Universitätsspital Zürich, Zürich
 		Kantonale Ethikkommission Zürich 09.09.2025
2025-01263 Cohort of infectious diseases in hematopoietic stem cell transplant patients non clinical, involving persons monocentric A Pr Dionysios Neofytos Geneva University Hospitals Geneva University Hospitals, Geneva
 		Commission Cantonale d'éthique de la recherche Genève (CCER) 03.09.2025
2025-01262 Development of a Miniature Intraoral Robot (MIR) – Collection of mouth opening data personal data/biological material monocentric PD, Dr. Jenni Hjerppe, PhD University of Zürich University of Zürich, Clinic of Reconstructive Dentistry, Zürich
 		Kantonale Ethikkommission Zürich 26.08.2025
2025-01261 Traitement de l’inégalité de longueur du membre inférieur par clou motorisé intramédullaire. personal data/biological material monocentric Pr/Dimitri/Ceroni University hospital of Geneva Hôpitaux Universitaires de Genève, Genève
 		Commission Cantonale d'éthique de la recherche Genève (CCER) 16.12.2025
2025-01260 Humour in adolescents on the autism spectrum: a window into cognition and a tool for well-being clinical trial other clinical trials monocentric A Prof. Dr. Mirella Manfredi University of Zurich University of Zurich, Zurich
 		Kantonale Ethikkommission Zürich 14.08.2026 yes
2025-01259 Development of an Algorithm for Detecting Ventilatory Thresholds Using Standard Earphones During Exercise via Acoustic Signals non clinical, involving persons monocentric A Dr. Jonathan Wagner Department of Sport, Exercise and Health Department of Sport, Exercise and Health; University of Basel, Basel
 		Ethikkommission Nordwest- und Zentralschweiz EKNZ 04.08.2025
2025-01258 Assessing severity and need for delivery in early onset preeclampsia before 32 weeks of gestation (AsSeDePre32) personal data/biological material monocentric Dr. med. Katrin De Giacomo Universitätsfrauenklinik Basel Universitätsfrauenspital, Basel
 		Ethikkommission Nordwest- und Zentralschweiz EKNZ 23.07.2025
2025-01256 Clinical Characterisation of Inborn Errors of Immunity personal data/biological material monocentric Maarja Soomann University Children’s Hospital Zurich University Children’s Hospital Zurich, Zurich
 		Kantonale Ethikkommission Zürich 14.11.2025
2025-01254 Aggressive treatment and PALliative care at the end of Life of patients with cAnCEr admitted in ICU (PALACE) personal data/biological material monocentric Prof. Dr. med. Sascha David King's College Hospital University Hospital Zürich, Institute of Intensive Care Medicine, Zürich
 		Kantonale Ethikkommission Zürich 22.08.2025
2025-01253 Association between Frailty status change and epigenetic age acceleration (EAA) personal data/biological material monocentric Prof. Dr. med. DrPH Heike A. Bischoff-Ferrari Universitäre Altersmedizin FELIX PLATTER Universitäre Altersmedizin FELIX PLATTER, Basel
 		Kantonale Ethikkommission Zürich 03.03.2026
2025-01252 Feasibility and Acceptability of an Artificial Intelligence (AI)-Assisted Chatbot for Conducting Structured Depression Questionnaire in Psychiatric Patients non clinical, involving persons monocentric A Prof. Dr. med. Sebastian Olbrich Psychiatric University Hospital Zurich University Hospital of Psychiatry, Zurich
 		Kantonale Ethikkommission Zürich 12.09.2025 Study has ended
2025-01251 Patient Perspectives on the Management of Uncomplicated Urinary Tract Infections with a Focus on Antibiotic-Sparing Treatment: A Qualitative Study non clinical, involving persons monocentric A PD Dr med Andreas Plate University Hospital Zürich, Institute of Primary Care University Hospital Zürich, Institute of Primary Care, Zürich
 		Kantonale Ethikkommission Zürich 10.10.2025
2025-01250 Phase 3, Multicenter, Randomized, Open-label Clinical Study of GSK5764227, a B7-H3 Antibody Drug Conjugate (ADC), compared with Topotecan in Participants with Relapsed Small Cell Lung Cancer (SCLC) clinical trial drugs phase 3 multicentric C Dr. Andreas Michael Schmitt GlaxoSmithKline GmbH & Co, KG Universitätsspital Basel, Basel
CHUV, Lausanne 		Ethikkommission Nordwest- und Zentralschweiz EKNZ Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 14.11.2025
2025-01249 Genetic Risks in Pediatric-onset, compared to adult-onset inflammatory bowel disease personal data/biological material monocentric Dr. med. Christiane Sokollik Kinderspital Bern Pediatric Gastroenterology, Hepatology and Nutrition; Kinderklinik, University of Bern, Bern
 		Kantonale Ethikkommission Bern 17.09.2025