| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-D0059 |
20230222 - Measurement of Samples with Tina-quant Lp(a) RxDx to Identify Participants with Elevated Lipoprotein(a) for Prevention of First Major Cardiovascular Events and A Double-blind, Random More ... |
clinical trial | in vitro diagnostic medical devices CDx | multicentric | C2 | PD Dr. med. Stefan Bilz | AMGEN |
HOCH Health Ostschweiz Kantonsspital St.Gallen Klinik für Endokrinologie, Diabetologie, Osteologie und Stoffwechselerkrankungen, St Gallen Inselspital Universitätsklinik für Kardiologie, Bern Luzern More ... |
Ethikkommission Ostschweiz (EKOS) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Com More ... | 17.07.2025 | ||||
| 2025-D0058 | The Susatu PHOENIX Trial ‘SPOT’ - A prospective, single-center, interventional trial to determine the clinical performance of a novel osteosynthesis material detector in comparison to standard clinica More ... | clinical trial | medical devices | monocentric | C2 | PD Dr. med. Michael Schär | susatu GmbH |
Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 10.11.2025 | |||||
| 2025-D0057 |
A Study of Patients with Lower Extremity Acute Limb Ischemia to Remove Thrombus with the IndigoTM Aspiration System |
clinical trial | medical devices | monocentric | A1 | Dr. med. Rafael Trunfio | Penumbra, Inc |
CHUV-Lausanne University Hospital, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.01.2026 | |||||
| 2025-D0056 | Early feasibility evaluation of the UniBE hybrid closed-loop insulin delivery system in Type 1 Diabetes: UBLoop - Genesis | clinical trial | medical devices | monocentric | C2 | Prof. Dr. med. Markus Laimer | University of Bern |
Universitätsklinik für Diabetologie, Endokrinologie, Ernährungsmedizin & Metabolismus (UDEM), Inselspital, Universitätsspital, CH-3010 Bern |
Kantonale Ethikkommission Bern | 10.11.2025 | |||||
| 2025-D0055 | Prospective evaluation of the Laryngeal Mask Singularity® in adult patients with or without neuromuscular blockade under clinical conditions | clinical trial | medical devices | monocentric | A1 | Prof. Dr. Alexander Dullenkopf | Spital Thurgau Frauenfeld |
Spital Thurgau Frauenfeld, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 12.06.2025 | |||||
| 2025-D0054 | Exploration of the functional effect of different hearing aid noise reduction algorithms in an ecologically valid conversational situation | clinical trial | medical devices | monocentric | A1 | Josephine Hollenbach | Sonova AG |
Sonova AG, Stäfa |
Kantonale Ethikkommission Zürich | 05.09.2025 | Study has ended | ||||
| 2025-D0053 | An international, multi-centre observational study to evaluate safety, performance, and clinical benefit of the BeFlow Iliac Covered Stent System | clinical trial | medical devices | monocentric | A1 | Dr Med Maria Antonella Ruffino, MD, EBIR | Bentley InnoMed GmbH |
Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 01.10.2025 | |||||
| 2025-D0052 | Certified Comprehensive Eye-Movement Examination in Children with Attention Deficit Hyperactivity Disorder: An Objective, Reproducible and Quantitative Diagnosis in 15 Minutes? | clinical trial | medical devices | multicentric | A1 | Dr. med. Dr. sc. nat. Christine Schneider | Onovis Augenpraxis |
Kinderarztpraxis ADHS Diagnostik und Therapie bei Kindern und Jugendlichen, Bern Onovis Augenpraxis, Bern |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 03.09.2025 | yes | |||
| 2025-D0051 | MR45625: A PHASE IIIb, MULTICENTER, SINGLE-ARM STUDY ASSESSING THE EFFECTIVENESS, SAFETY AND PATIENT REPORTED OUTCOMES OF A 36-WEEK REFILL EXCHANGE REGIMEN FOR THE PORT DELIVERY SYSTEM WITH RANIBIZUMA More ... | clinical trial | combination drugs/devices | multicentric | C2 | Prof. Dr. med. Justus Garweg | F. Hoffmann-La Roche AG, Grenzacherstrasse 124, 4058 Basel |
Berner Augenklinik, Bern Pallas Kliniken Olten, Louis Giroud-Strasse 20/26 HOCH Health Ostschweiz, Kantonsspital St. Gallen Augenklinik Rorschacher |
Kantonale Ethikkommission Bern | Ethikkommission Ostschweiz (EKOS), Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.09.2025 | ||||
| 2025-D0050 | Prospective study to evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) to increase the survival of autologous fat transfer for breast reconstruction after radiotherapy. A randomized contr More ... | clinical trial | medical devices | monocentric | A1 | Dr. André-Lévigne Dominik | Service de chirurgie plastique, reconstructive et esthétique, Hôpitaux Universitaires de Genève |
Service de chirurgie plastique, reconstructive et esthétique, Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 01.10.2025 | |||||
| 2025-D0049 | “ASCEND CSP” A Stylet-Driven ICD Lead Intended for Conduction System Pacing IDE Study | clinical trial | medical devices | monocentric | C2 | Professor Dr. med. Haran Burri | Abbott Medical (represented in EU by St. Jude Medical Coordination Center BV |
Hôpitaux Universitaires de Genève (HUG), Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.11.2025 | |||||
| 2025-D0048 | A Single-Center, First-in-Human, Randomized, Controlled, Feasibility Study of a New Device for the Real-Time Continuous Monitoring of the Injection Pressure of Local Anesthetic in Subjects Undergoing More ... | clinical trial | medical devices | monocentric | C2 | Dr. med. Roberto Dossi | Service of Anesthesia, Ospedale Regionale di Bellinzona e Valli, EOC |
Ospedale Regionale di Bellinzona e Valli, EOC, Bellinzona |
Comitato etico cantonale Ticino | 27.08.2025 | |||||
| 2025-D0047 | An open-label, multi-national, multi-centre, randomised, single-period parallel study to assess the efficacy, safety and utility of fully closed-loop insulin delivery compared to standard insulin ther More ... | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. et phil. Lia Bally | Inselspital |
Inselspital, Universitätsspital Bern Universitätsklinik für Diabetologie, Endokrinologie, Ernährungsmedizin und Me-tabolismus UDEM, 3010 Bern |
Kantonale Ethikkommission Bern | 18.06.2025 | |||||
| 2025-D0045 | Neurorehabilitation of cognitive deficits in multiple sclerosis using an adaptive cognitive exergame: randomized, controlled, multi-center clinical trial | clinical trial | medical devices | multicentric | C2 | Prof. Arseny Sokolov | CHUV |
CHUV, Lausanne Inselspital Bern, Bern Ambulante Reha Triemli, Kliniken Valens, Birmensdorferstrasse 497 |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 02.09.2025 | ||||
| 2025-D0044 | Clinical evaluation of polymer-infiltrated ceramic network (PICN) material versus zirconia lithium silicate (ZLS) ceramic for the restoration of worn posterior dentitions – A randomized controlled spl More ... | clinical trial | medical devices | monocentric | A1 | PD Dr. med. dent. Pune Nina Paqué | Center of Dental Medicine |
Center of Dental Medicine, Zürich |
Kantonale Ethikkommission Zürich | 17.10.2025 | |||||
| 2025-D0043 | PICO Negative Pressure for the Treatment of Uninfected Foot Ulcers and Wound Dehiscence - an unblinded, randomized-controlled, superiority trial (BALPIC Trial) | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Ilker Uçkay | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 20.01.2026 | |||||
| 2025-D0040 | Prospective-randomized trial to demonstrate superiority of SuperCable vs. conventional steel wire for closure after a median sternotomy | clinical trial | medical devices | monocentric | A2 | PD Dr. med. Héctor Rodríguez Cetina Biefer | University Hospital Zürich |
USZ, Zurich |
Kantonale Ethikkommission Zürich | 19.08.2025 | |||||
| 2025-D0039 | BIOresorbable scaffold combined with drug-coated balloons for HYBRID percutaneous coronary intervention versus a conventional drug-eluting stent-based strategy in patients with long and diffuse corona More ... | clinical trial | medical devices | multicentric | A2 | Prof. Dr med. Gregor Leibundgut | Hôpitaux Universitaires de Genève |
Universitätsspital Basel, Klinik für Kardiologie, Basel Hôpitaux Universitaires de Genève, Service de Cardiologie Interventionnelle Rue Gabr |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission Cantonale d'éthique de la recherche Genève (CCER) | 30.07.2025 | ||||
| 2025-D0038 | Monocentric prospective, randomized, non-blinded, active-controlled trial to evaluate the non-inferiority of functional magnetic stimulation (FMS) using the Tesla Chair compared to physiotherapy in More ... | clinical trial | medical devices | monocentric | A1 | Dr. med. Peter Kleimann | Kantonsspital Winterthur |
Frauenklinik Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 26.09.2025 | |||||
| 2025-D0037 | A European Multi-Center, Prospective, Single-Arm, Observational Study to Evaluate Real-World Outcomes for the Ion Endoluminal System | clinical trial | medical devices | monocentric | A1 | PD Dr. Thomas Gaisl | Intuitive Surgical, Inc. |
Universitätsspital Zürich, Klinik für Pneumologie, Zürich |
Kantonale Ethikkommission Zürich | 19.08.2025 | |||||