| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-00934 | Prospective observational study to characterize heart failure with preserved ejection fraction - an integrative approach that combines quantitative MRI, metabolomics, and genomics with machine learnin More ... | non clinical, involving persons | multicentric | B | Prof. Roger Hullin | CHUV |
CHUV, Lausanne Hopitaux Universitaires de Geneve (HUG), Genève |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission Cantonale d'éthique de la recherche Genève (CCER) | 28.10.2022 | |||||
| 2022-00932 | The Malignant Potential of Pancreatic Cysts: Artificial Intelligence Applied to Imaging and Clinical features | personal data/biological material | multicentric | PD Dr Martin Bolli | Clarunis University Center for Gastrointestinal and Liver Diseases Basel |
Clarunis Unversity Center for Gastrointestinal and Liver Diseases, Basel Hirslanden Klinik Beau-Site, Bern Lindenhofspital, Bern Spitalzentrum Oberwallis, Visp Kantonsspital Baselland, Liestal Hirslan More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.07.2022 | ||||||
| 2022-00931 | Defining Benchmarks in Open & Minimally-Invasive Gastrectomy – A retrospective global analysis | personal data/biological material | monocentric | Prof. Dr. med. Christian Gutschow | Department of Visceral- and Transplant Surgery, University Hospital Zurich |
Department of Visceral- and Transplant Surgery, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 21.06.2022 | |||||||
| 2022-00930 | Consequences of caffeine intake in teenagers: Effects on sleep, reward processing, risk-taking, and underlying cerebral mechanisms under conditions of sleep restriction | clinical trial | other clinical trials | monocentric | A | Dr. Carolin Reichert | Centre for Chronobiology |
Centre for Chronobiology, Psychiatric Hospital of the University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.06.2022 | yes | ||||
| 2022-00929 |
European microCirculatory Resistance and Absolute Flow Team The Euro-CRAFT Registry Prospective evaluation of the impact of coronary themodilution on clinical outcomes in chronic coronary syndromes |
non clinical, involving persons | monocentric | A | Dr Stephane Fournier | CoreAalst BV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.08.2023 | ||||||
| 2022-00928 | Dupilumab for chronic prurigo: case series on effectiveness, safety and quality of life | non clinical, involving persons | monocentric | A | Prof. Dr. med. Jürg Hafner | Dermatologische Klinik, Universitätsspital Zürich |
Dermatologische Klinik, Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.07.2022 | ||||||
| 2022-00927 | CDYP688A12101: Eine multizentrische, offene Phase-I/II-Studie zu DYP688 bei Patientinnen und Patienten mit metastasiertem uvealem Melanom (MUM) oder anderen GNAQ/11-mutierten Melanomen | clinical trial | drugs | phase 1/2 | monocentric | C | Prof. Dr. Reinhard Dummer | Novartis Pharma AG Schweiz |
Universitätsspital Zürich, Dermatologische Klinik, Zürich |
Kantonale Ethikkommission Zürich | 29.07.2022 | yes | |||
| 2022-00926 | Biomarkers of Alcohol Use Disorder (AUD): Stress- and neurodegeneration-related biomarker profiles during AUD treatment | non clinical, involving persons | monocentric | A | Prof. Dr. Boris Quednow | Psychiatric University Hospital Zurich, University of Zurich |
Psychiatric University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 12.07.2022 | ||||||
| 2022-00925 | High Resolution Anoscopy algorithm in anal cancer screening: A single-center 9-year experience. | personal data/biological material | monocentric | Dr Fabian Grass | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 29.06.2022 | Study has ended | ||||||
| 2022-00923 | Comparative bioavailability study of a new Lorazepam IBSA 2.5 mg orodispersible film vs. Tavor® 2.5 mg tablets and Tavor® 2.5 mg orodispersible tablets in healthy volunteers under fasting conditions | clinical trial | drugs | phase 1 | monocentric | C | Dr. Milko Radicioni | IBSA Institut Biochimique S.A. |
CROSS Research S.A. Phase I Unit, CH-6864 Arzo, Switzerland |
Comitato etico cantonale Ticino | 09.06.2022 | Study has ended | |||
| 2022-00922 | Prevalence of post COVID-19 condition in inpatients and outpatients, five and eight months after a COVID-19 infection | non clinical, involving persons | multicentric | A | Prof. Dr. med. Balthasar Hug |
Cantonal Hospital Lucerne, lucerne Notfallpraxis Permanence Bahnhof Luzern, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.06.2022 | ||||||
| 2022-00921 | Fracture Database of the University Hospital Basel: A REDCap assisted Reliability and Validity Study of Fracture Classifications of the Distal Radius | personal data/biological material | monocentric | Murat Bilici |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.06.2022 | ||||||||
| 2022-00920 | A Phase III, Randomised, Open-Label Study of Savolitinib in Combination With Osimertinib Versus Platinum-Based Doublet Chemotherapy in Participants With EGFR Mutated MET Overexpressed and/or Amplified More ... | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med. Dr. phil. Sacha Rothschild | AstraZeneca AB |
Kantonsspital Baden AG, Baden Universitätsspital Basel, Basel Stadtspital Zürich Triemli, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 13.10.2022 | |||
| 2022-00919 |
Management der akuten Herzinsuffizienz im Kantonsspital Baselland (KSBL), Schweiz, eine retrospektive Beobachtungsstudie und medizinisches Audit |
personal data/biological material | monocentric | Prof. Dr. med. Jörg Leuppi | Medizinische Universitätsklinik Kantonsspital Baselland |
Kantonsspital Baselland, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.06.2022 | |||||||
| 2022-00918 | CKJX839D12303: A multi-center, randomized, double-blind, placebo-controlled, parallel-group Phase IIIb study evaluating the effect of inclisiran on atherosclerotic plaque progression assessed by coron More ... | clinical trial | drugs | phase 3 | multicentric | C | Marco Valgimigli | Novartis Pharma Schweiz AG |
EOC Istituto Cardiocentro Ticino, Lugano Geneva University Hospital, Geneve EOC, Bellinzona |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino | 25.08.2022 | |||
| 2022-00917 | Clinical presentation, treatment patterns and course of rare or uncommon arterial conditions: the RARE-A retrospective study. | personal data/biological material | monocentric | PD Dr. med. Stefano Barco | University of Zurich |
USZ, Zürich |
Kantonale Ethikkommission Zürich | 15.07.2022 | |||||||
| 2022-00916 | Lipoprotéine(a) et athérosclérose subclinique chez des enfants hypercholestérolémiques. | personal data/biological material | monocentric | Ms Nathalie BRUN | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.12.2022 | Study has ended | ||||||
| 2022-00915 | DD-cfDNA/PIRCHE-II Study: Calibrating the donor-derived cell-free DNA (DD-cfDNA) baseline in the first year after kidney transplantation to the Predicted Indirectly Recognizable HLA-Epitopes (PIRCHE-I More ... | non clinical, involving persons | monocentric | A | PD Dr. Thomas Schachtner | University Hospital Zurich, Division of Nephrology |
USZ, Division of Nephrology, Zurich |
Kantonale Ethikkommission Zürich | 16.08.2022 | ||||||
| 2022-00914 | Optimal cup positioning in trapeziometacarpal joint arthroplasty by using individual 3D printed implantation guides. A cadaver study | deceased persons | monocentric | Dr. Susanne Habelt | Hand und Plastische Chirurgie Kantonsspital St. Gallen |
Hand und Plastische Chirurgie Kantonsspital St. Gallen, 9007 St. Gallen |
Kantonale Ethikkommission Zürich | 05.08.2022 | |||||||
| 2022-00913 | Golden angle Radial Sparse Parallel (GRASP) – DCE Perfusion and DSC Perfusion MRI to differentiate true Progression from Pseudoprogression in High Grade Gliomas | personal data/biological material | monocentric | MD Ramona-Alexandra Todea | University Hospital of Basel |
University Hospital of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.06.2022 | |||||||