| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-02581 | TRI0386 - Identification of a SomaScan proteomic disease signature for Sjogren’s disease (SjD) and sicca | personal data/biological material | monocentric | Dr. Rainer Hillenbrand | Novartis Pharma AG |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.01.2025 | |||||||
| 2024-02580 | Impact of Daratumumab, Lenalidomide, Bortezomib and Dexamethasone as first-line induction therapy on stem cell collection and quality in newly diagnosed multiple myeloma (MM) patients with navelbine-b More ... | personal data/biological material | multicentric | Prof. Dr. med. Christoph Renner | Klinik Hirslanden Zürich |
Klinik Hirslanden, Zürich Universitätsspital Basel, Basel |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.06.2025 | ||||||
| 2024-02579 | Mentalization Based Treatment (MBT) in help seeking youths with a Clinical High-Risk condition for Psychosis (CHR-P): a randomized controlled trial | clinical trial | other clinical trials | monocentric | B | Prof. Armando Marco | CHUV - ERA - Psychiatrie |
CHUV, 1004 |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.07.2025 | yes | ||||
| 2024-02577 | C4391024/AN INTERVENTIONAL, OPEN-LABEL, RANDOMIZED, MULTICENTER PHASE 3 STUDY OF PF-07220060 PLUS LETROZOLE COMPARED TO CDK4/6 INHIBITOR PLUS LETROZOLE IN PARTICIPANTS OVER 18 YEARS OF AGE WITH HORMON More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Razvan Andrei Popescu | Pfizer Inc. |
Tumor Zentrum Aarau, Aarau Inselspital, Universitätsspital Bern, Bern Universitätsspital Basel, Basel Spital Thurgau AG, Frauenfeld CHUV (Centre Hospitalier Universitaire Vaudois), Lausanne KS Wintert More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 20.03.2025 | |||
| 2024-02576 | Evaluation of the implementation of a CMV cell-mediated immune assay in the routine clinical practice for the prevention of CMV infection in CMV-seropositive kidney transplant recipients | personal data/biological material | monocentric | Oriol Manuel | CHUV - Maladies infectieuses |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 25.03.2025 | |||||||
| 2024-02575 | Development of a consensus version of the German Vocal Fatigue Index | personal data/biological material | monocentric | PD KD Dr. med. J. Bohlender | University Hospital Zurich |
Abteilung Phoniatrie und Klinische Logopädie, Klinik für Ohren-, Nasen-, Hals- und Gesichtschirurgie, Universitätsspital Zürich, Zurich |
Kantonale Ethikkommission Zürich | 23.05.2025 | Study has ended | ||||||
| 2024-02574 |
Registry study on online adaptive radiotherapy with the Ethos linear accelerator - ART Registry Study Registerstudie zur online adaptiven Radiotherapie mit dem Ethos-Linearbeschleuniger – ART Registe More ... |
personal data/biological material | monocentric | Dr. med. Jonathan Hollmann | Klinik für Strahlentherapie und Radioonkologie, Universitätsspital Basel |
Universitätsspital Basel, Klinik für Strahlentherapie und Radioonkologie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.01.2025 | |||||||
| 2024-02572 | PSMA-PET/CT for Unfavorable Intermediate-Risk Prostate Cancer: Standard Practice or Premature Hype? | personal data/biological material | monocentric | Dr. med. Lukas Prause | Dept. of Urology |
Dept. of Urology Cantonal Hospital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.01.2025 | |||||||
| 2024-02570 | YounG AsthMa E-health: Utilisation des outils numériques dans le soutien à l’éducation thérapeutique des enfants et des adolescent·e·s atteints d’asthme (GAME) | non clinical, involving persons | monocentric | A | Prof HES Associé Mark Marston | Haute École de la Santé La Source |
Institut et Haute École de la Santé La Source, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.02.2025 | yes | |||||
| 2024-02568 | A monocentric, randomized, double-blind study to assess the feasibility of conducting a full-scale randomized controlled trial (RCT) assessing the effect of carbidopa/levodopa ratio on orthostatic hyp More ... | clinical trial | drugs | phase 1/2 | monocentric | C | Dr Julien Bally | CHUV - Neurologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 19.02.2025 | ||||
| 2024-02567 | Understanding the socio economic determinants of environmental exposures in children and adolescents (CIFAR-SNSF) | personal data/biological material | monocentric | Pr Silvia Stringhini | Hôpitaux universitaire de Genève |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.05.2025 | |||||||
| 2024-02565 | Performance of VENTANA MET (SP44) RxDx Assay with OptiView DAB IHC Detection on the BenchMark ULTRA Instrument as a Diagnostic Device for the Assessment of MET Status of Locally Advanced or Metastatic More ... | personal data/biological material | multicentric | Prof. Dr. med Sacha Rothschild | AstraZeneca AB |
Kantonsspital Baden, Onkologie und Hämatologie, Im Ergel 1, 5404 Baden, Baden Stadtspital Zürich Triemli, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 28.03.2025 | ||||||
| 2024-02564 | Vaccine skepticism in Switzerland – Did the COVID-19 pandemic influence the way the Swiss population perceives vaccines? | personal data/biological material | monocentric | PD Dr. med. Esther Künzli | Swiss TPH |
Swiss TPH, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.01.2025 | |||||||
| 2024-02563 |
SAKK 89/24 Assessing physicians and cancer patients’ preferences for quality of life (QoL) and length of life (LoL) in oncology: A study in gastric and esophageal cancer |
non clinical, involving persons | multicentric | A | Dr. med. Mickael Chevallay | Swiss Cancer Institute |
HUG - Hôpitaux universitaires de Genève, Service de chirurgie viscérale, Genève Kantonsspital Aarau - Onkologie, Hämatologie & Transfusionsmedizin, Aarau Kantonsspital Baden, Baden St. Claraspital, B More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.05.2025 | |||||
| 2024-02562 | Prognosis improvement of unprovoked vEnous THromboEmbolism with the use of a shared decision-making process including a time-dependent multicomponent risk prediction scores inteRvention. An internatio More ... | clinical trial | other clinical trials | monocentric | A | Prof Marc Righini | CHU de Brest |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 17.06.2025 | |||||
| 2024-02561 | Optimised kangoroo care to support breastfeeding and healthy microbiome acquisition in very preterm infants (MINI-KAB) - a substudy of the multicentre, parallel cluster randomised NeoDeco study | non clinical, involving persons | multicentric | A | Dr. Kerstin Jost | University Children’s Hospital Basel (UKBB) |
University Children’s Hospital Basel (UKBB), Basel Universitätsspital Zürich Klinik für Neonatologie, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 14.02.2025 | yes | ||||
| 2024-02560 | RECOVER: Cardiac REhabilitation COhort at the Medicine Campus DaVos to invEstigate Recovery | non clinical, involving persons | monocentric | A | PD Dr. med. David Niederseer |
Hochgebirgsklinik Davos, Medicine Campus Davos, 7265 Davos Wolfgang |
Kantonale Ethikkommission Zürich | 01.07.2025 | |||||||
| 2024-02558 | Exploration of thyroid cancers microenvironment on metastasis and tumor aggressiveness | personal data/biological material | monocentric | François Gorostidi | CHUV - ORH - Chirurgie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.01.2025 | |||||||
| 2024-02557 | Gastrite auto-immune : épidémiologie, analyse sérologique et impact thérapeutique. Rétrospective sur 10 ans dans un centre tertiaire suisse. | personal data/biological material | monocentric | Dr Maxime Ringwald | CHUV - Immunologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.01.2025 | |||||||
| 2024-02556 | Analysis of the correlation of genetic risk factors for attention-deficit/hyperactivity disorder (ADHD) with symptom severity in patients | non clinical, involving persons | multicentric | A | Prof. Dr. Sven Cichon | Universitätsspital Basel und Universität Basel |
University Hospital Basel, Basel Psychiatrische Dienste Aargau AG, Rheinfelden Kompetenzzentrum für AD(H)S & Folgekrankheiten, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 12.02.2025 | |||||