| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01240 | Safety and Efficacy of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Candidemia. | clinical trial | drugs | phase 2 | monocentric | B | Prof. Thierry CALANDRA | Radboudumc University Medical Centre |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 12.09.2023 | ||||
| 2023-01239 | CLOU064A2304 - A global, multicenter, randomized, double-blind, double-dummy, parallel-group, Phase 3b study to assess the efficacy, safety, and tolerability of remibrutinib 25 mg b.i.d. in comparison More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Claudia Lang | Novartis Pharma Schweiz AG |
USZ, Zürich HUG, Geneva Kantonsspital St. Gallen, St. Gallen IZZ, Zürich |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 10.10.2023 | |||
| 2023-01237 | Detection and quantification of folates and folate receptor autoantibodies in the blood/saliva of patients with depression | personal data/biological material | monocentric | PD Dr. Michele Visentin | Universitätsspital Zürich |
Institut für Pharmakologie und Toxikologie USZ, 8952 |
Kantonale Ethikkommission Zürich | 18.08.2023 | |||||||
| 2023-01236 | Défaut d’opacification des sinus veineux cérébraux à l’angio-CT post-mortem : artéfact en lien avec la cause du décès ? | deceased persons | monocentric | Prof. Jérôme Schmid | Centre Universitaire Romand de Médecine Légale (CURML), site de Genève |
Haute école de santé, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 29.08.2023 | Study has ended | ||||||
| 2023-01235 | Incidence and severity of cerebral palsy after intraventricular hemorrhage and periventricular hemorrhagic infarction in a cohort of Swiss premature infants | personal data/biological material | monocentric | PD Dr. sc. nat. Mark Adams | Klinik für Neonatologie |
Dep. of Neonatology, University Hospital, Zurich |
Kantonale Ethikkommission Zürich | 08.03.2024 | |||||||
| 2023-01234 | CYTB323G12101: An open-label, multi-center, phase 1/2 study to assess safety, efficacy and cellular kinetics of YTB323 in participants with severe, refractory systemic lupus erythematosus (srSLE) | clinical trial | gene therapy | multicentric | C | Prof. Dr. med. Britta Maurer | Novartis Pharma Schweiz AG |
Inselspital, Bern CHUV, Lausanne |
Kantonale Ethikkommission Bern | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.10.2023 | ||||
| 2023-01231 | Uso di wearable devices per il monitoraggio di pazienti ipotiroidei. | non clinical, involving persons | monocentric | A | Prof Dr med Pierpaolo Trimboli | Ente Ospedaliero Cantonale |
Ente Ospedaliero Cantonale, Bellinzona |
Comitato etico cantonale Ticino | 28.09.2023 | ||||||
| 2023-01230 | Supervised GLA:D Intervention Versus a Supported Home-Based Version Among Patients with Hip or Knee Osteoarthritis: A Feasibility Study. | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Jan Taeymans | Berner Fachhochschule |
Berner Fachhochschule, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.08.2023 | |||||
| 2023-01229 | Development of a predictive model for sudden unexpected death in Epilepsy (SUDEP) in a high-risk population: a multicentre international retrospective case-control study (EMU SUDEP Study) | personal data/biological material | monocentric | Prof Philippe Ryvlin | NYU |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.04.2024 | |||||||
| 2023-01228 | Psychometric evaluation of the MED-fLAG (MEDication Literacy Assessment in Geriatric patients): structural validity and internal consistency | non clinical, involving persons | monocentric | A | Dre. Jenny Gentizon | IUFRS/CHUV UNIL |
IUFRS CHUV/UNIL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.08.2023 | Study has ended | |||||
| 2023-01227 | Coding in populations of single neurons in human temporal lobe from invasive recordings in epilepsy patients | non clinical, involving persons | multicentric | A | Dr. Debora Ledergerber | Swiss Epilepsy Center, Klinik Lengg AG |
Swiss Epilepsy Center, Klinik Lengg AG, Zurich Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 19.04.2024 | |||||
| 2023-01226 | Überleben bei Anastomoseninsuffizienz nach Rektumresektion, eine Frage des Managements? Rektum Insuffizienz Studie | personal data/biological material | monocentric | PD Dr. med. Ignazio Tarantino |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 11.07.2023 | ||||||||
| 2023-01225 | Quantification du sepsis par un algorithme au sein du Service des urgences du CHUV | personal data/biological material | monocentric | PD Dr. Sylvain Meylan | CHUV - Médecine intensive |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.09.2023 | |||||||
| 2023-01224 | Three-dimensional corrective osteotomies of Madelung deformities using patient-specific guides | non clinical, involving persons | monocentric | A | Prof. Dr. med. A. Schweizer | Univeristätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 07.11.2023 | yes | |||||
| 2023-01223 | Roll Over StudY for Patients Who Have Completed a Previous Oncology Study with Durvalumab and Are Judged by the Investigator to Clinically Benefit From Continued Treatment | clinical trial | drugs | phase 3 | monocentric | C | Dr Hasna BOUCHAAB | Astra Zeneca AB |
Centre hospitalier Universitaire Vaudois (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.03.2024 | ||||
| 2023-01222 | A Phase 1-3 Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ION363 in Amyotrophic Lateral Sclerosis Patients with Fused in Sarcoma Mutations More ... | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. Christoph Neuwirth | Ionis Pharmaceuticals, Inc. |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 05.10.2023 | yes | |||
| 2023-01221 | Virtual monoenergetic imaging to reduce metal artifacts in tin-prefiltered photon counting CT of the ankle | personal data/biological material | monocentric | Prof. Dr. Reto Sutter | University Hospital Balgrist |
University Hospital Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 15.08.2023 | |||||||
| 2023-01220 | Physiological factors affecting myocardial blood flow as assessed by quantitative positron emission tomography myocardial perfusion imaging | personal data/biological material | monocentric | Prof. Dr. med. Ronny Ralf Büchel | University Hospital Zurich |
University Hospital Zuricu, Zürich |
Kantonale Ethikkommission Zürich | 22.08.2023 | |||||||
| 2023-01219 | Monitoring of Torque Teno Virus Levels in Lung Transplantation as a Marker for Immunosuppression | non clinical, involving persons | monocentric | A | Prof. Dr. med. Nicolas Müller | University Hospital Zurich |
University Hospital of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 15.09.2023 | ||||||
| 2023-01218 | Monotherapy with a P2Y12 inhibitor followed by a direct-acting oral anticoagulant in patients with ATRial fIbrillation undergoing suprafleX coronary stent implantation (MATRIX-2) | clinical trial | other clinical trials | multicentric | B | Prof. Stephan Windecker | Insel Gruppe AG Bern University Hospital |
Inselspital, Bern University Hospital, Bern Universitätsspital Basel, Klinik für Kardiologie, Basel Kantonsspital Baselland, Liestal Hôpitaux Universitaires de Genève,, Genève Cardiocentro Ticino Inst More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino | 29.09.2023 | ||||