| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-01734 | A Randomized, Multicenter, Open-label, Phase III Study of Lurbinectedin Single-Agent or Lurbinectedin in Combination with Irinotecan versus Investigator’s Choice (Topotecan or Irinotecan) in Relapsed More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Hasna Bouchaab | PharmaMar S.A. |
Centre Hospitalier Universitaire Vaudois, Lausanne Kantonspital Baselland, Baselland University Hospital Basel, Basel Spital Thurgau AG, Munsterlingen / Frauenfeld Istituto Oncologico della Svizzera I More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cantonale Ticino | 17.07.2023 | |||
| 2022-01733 | Long-term outcome of patients treated with a leadless pacemaker (MICRA) in Switzerland | personal data/biological material | multicentric | Dr. med. Tardu Özkartal | Cardiocentro Institute Ticino - EOC |
Cardiocentro Institute Ticino, Lugano Universitätsspital Bern, Bern Universitätsspital Basel, Basel Kantonsspital Luzern, Luzern Kantonsspital St. Gallen, St. Gallen Universitätsspital Zürich, Zürich |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 16.03.2023 | ||||||
| 2022-01732 | Association between left-ventricular unloading during extracorporeal cardio-pulmonary resuscitation in patients with cardiac arrest caused by acute myocardial infarction on 30-day mortality. | personal data/biological material | monocentric | Prof. Dr. | Charité – University Hospital Berlin |
Universitätsspital Zürich USZ, Zürich |
Kantonale Ethikkommission Zürich | 11.07.2023 | |||||||
| 2022-01728 | Evolution of growth following anti-TNFα therapy in paediatric Crohn’s disease. | personal data/biological material | monocentric | Dr Andreas Nydegger | CHUV - DFME |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 05.01.2023 | |||||||
| 2022-01726 | Predictability of astigmatism correction by arcuate incisions with a femtosecond laser using the Gauss approximation calculation. | personal data/biological material | monocentric | Prof. Dr. med. Bojan Pajic |
Orasis Augenklinik, Reinach AG |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.11.2022 | Study has ended | |||||||
| 2022-01725 | Retrospective study: Assessment of the suitability of the newborn screening for the prevention of an alimentary vitamin B12 deficiency in infancy. | personal data/biological material | multicentric | Prof. Dr. Martina Huemer |
Kinderspital Zürich, Zürich Inselspital Bern, Bern University Children’s Hospital Basel (UKBB), Basel Kantonsspital Aarau AG Kinderspital, Aarau Luzerner Kantonsspital Kinderspital, Luzern Ostschweize More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 16.02.2024 | |||||||
| 2022-01724 | MK-6598-001: A Phase 1, Open-label, Multicenter Study to Assess Safety, Tolerability, PK, and Efficacy of MK-6598 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Sol More ... | clinical trial | drugs | phase 1 | multicentric | C | PD Dr. med. Anastasios Stathis | Merck Sharp & Dohme Corp. Whitehouse Station, NJ (USA) |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona Hôpitaux Universitaires de Genève (HUG), Genève Kantonsspital St. Gallen, St. Gallen |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS), Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.12.2022 | |||
| 2022-01722 |
Mucosal Immunity: Influence on Infectious Viral Load: a prospective observational study |
non clinical, involving persons | monocentric | A | Prof. Isabella Eckerle | University Hospital of Geneva |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.12.2022 | ||||||
| 2022-01721 | Kardiale Gewebespende und Homograftgewinnung | personal data/biological material | monocentric | Dr med. Martin O. Schmiady | USZ |
USZ, Zürich |
Kantonale Ethikkommission Zürich | 18.10.2022 | |||||||
| 2022-01720 | OPtimisation of antiviral Therapy in Immunocompromised COVID-19 patients: a randomized factorial controlled strategy trial | clinical trial | drugs | phase 2 | multicentric | A | Prof. Alexandra Calmy | Geneva University Hospitals |
HUG, Geneva University of Basel, Department Biomedicine, Basel CHUV, Lausanne Zurich University Hospital, Zurich |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 31.10.2022 | |||
| 2022-01719 | Pediatric Acute Asthma Management in the Emergency Department and Associated Outcomes: A Pediatric Emergency Research Network Study (Global Asthma Study) | personal data/biological material | multicentric | PD Dr. med. Michelle Seiler | University Children's Hospital Zurich |
University Children's Hospital Zurich, Zurich Inselspital, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 18.10.2022 | ||||||
| 2022-01718 | A Pilot Study to Assess the Feasibility of Non-Invasive, Transcutaneous Glucose Measurement | non clinical, involving persons | monocentric | A | Fabien Rebeaud, Ph.D. | Spiden AG |
Spiden AG, Pfaeffikon SZ |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.10.2022 | ||||||
| 2022-01716 | Artificial Intelligence for the immune profiling of Hepatocellular carcinoma. | personal data/biological material | monocentric | Dr Antonia Digklia | Henri Mondor University Hospital |
chuv, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.11.2022 | |||||||
| 2022-01715 | Dermatological toxicity reactions in patients under anticancer therapies | personal data/biological material | monocentric | PD Dr. med. Cristina Mangas de Arriba |
Dermatology Department, Ospedale Regionale di Bellinzona e Valli, EOC, Bellinzona |
Comitato etico cantonale Ticino | 28.11.2022 | ||||||||
| 2022-01714 | THE IMPACT OF GROUP LEISURE ACTIVITIES ON QUALITY OF LIFE IN PARKINSON’S DISEASE PATIENTS: A CASE-CONTROL STUDY | clinical trial | other clinical trials | monocentric | A | PD Dr.med Salvatore Galati | Croce Rossa Svizzera (Sezione del Sottoceneri) |
Neurocentro della Svizzera Italiana, Lugano |
Comitato etico cantonale Ticino | 03.02.2023 | |||||
| 2022-01713 | Swiss Childhood Health and Nutrition Survey 2023 – Nationale Studie Gesundheit und Ernährung von Primarschülern 2023 | non clinical, involving persons | monocentric | A | Dr. Isabelle Herter-Aeberli | ETH Zurich |
ETH Zurich, Switzerland |
Kantonale Ethikkommission Zürich | 16.12.2022 | yes | |||||
| 2022-01712 | What is the outcome of haploidentical donor stem cell transplantations in the children's hospital of Zurich and how do the different regimens of haploidentical SCTs influence the prognosis of differen More ... | personal data/biological material | monocentric | Dr. med. Ulrike Zeilhofer | Kinderspital |
Abteilung für Stammzelltransplantation, Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 25.10.2022 | |||||||
| 2022-01711 | SVEPO-GP / Impact des modalités de Support Ventilatoire, du sevrage ventilatoire précoce et proactif, de la mobilisation précoce et du support nutritionnel délivré au cours de la période Post-Opératoi More ... | personal data/biological material | monocentric | Lise Piquilloud Imboden | CHUV-SMIA |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.10.2022 | |||||||
| 2022-01710 | Utilization of high flow nasal oxygen (HFNO) therapy on a respiratory ward during the COVID-19 pandemic, January 2020 - September 2022 | personal data/biological material | monocentric | PD Dr. med. Anne-Kathrin Brill | Universitätsklinik für Pneumologie |
University Hospital Bern (Inselspital), Bern |
Kantonale Ethikkommission Bern | 09.12.2022 | Study has ended | ||||||
| 2022-01709 |
PFLEBEO - Pflegeeinrichtungen – Bewegungsfreundliche Organisationen |
non clinical, involving persons | monocentric | A | PD Dr. Timo Hinrichs | University of Hamburg |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.11.2022 | Study has ended | |||||