BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2022-02133 Benefit-to-risk balance of coronary angiography in the critically ill personal data/biological material monocentric Dr Hamid Merdji Basel University Hospital University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 10.02.2023
2022-02132 Monocentric retrospective study of 341 children with Appendectomy: How frequent is oxyuriasis? personal data/biological material monocentric Prof. med. Henrik Köhler Kinderspital am Kantonsspital Aarau Kantonsspital Aarau, Aarau
Ethikkommission Nordwest- und Zentralschweiz EKNZ 03.03.2023
2022-02131 19767_A multicenter, international, randomized, active comparator-controlled, double-blind, doubledummy, parallel-group, 2-arm, Phase 3 study to compare the efficacy and safety of the oral FXIa inhibi More ... clinical trial drugs phase 3 multicentric C Prof. Dr. med. Angelo Auricchio Bayer AG Istituto Cardiocentro Ticino, Lugano
lnselspital Bern, Bern
Universitätsspital Basel, Basel
Kantonspital Aarau AG, Aarau
Kantonsspital Baden AG, Baden
Kantonsspital St. Gallen, St. Gallen
HFR Hôpital More ...
Comitato etico cantonale Ticino Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 13.02.2023 Study has ended
2022-02130 CAIN457C22301 - A randomized, parallel-group, double-blind, placebo-controlled, multicenter Phase III trial to evaluate efficacy and safety of secukinumab administered subcutaneously versus placebo, i More ... clinical trial drugs phase 3 multicentric C Prof. Dr. med. Andrea Rubbert-Roth Novartis Pharma Schweiz AG Kantonsspital St. Gallen, St. Gallen
Universitätsspital, Basel
HFR Fribourg – Hôpital Cantonal, Fribourg
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 16.02.2023
2022-02129 A two-part, randomized, placebo controlled, double blind, multicenter, Phase 3 study to evaluate the efficacy and safety of linerixibat for the treatment of cholestatic pruritus in participants with p More ... clinical trial drugs phase 3 monocentric C PD Dr. med. Benedetta Terziroli Beretta-Piccoli GlaxoSmithKline Research & Development Limited Epatocentro Ticino, Lugano
Comitato etico cantonale Ticino 27.02.2023 Study has ended
2022-02128 Post Intensive Care Syndrome in Swiss Pediatric survivors and their Families [PICSS-PF]: A Multi-center Longitudinal Observational Study non clinical, involving persons multicentric A Dr. Zahra Rahmaty IUFRS/University Hospital of Lausanne IUFRS, CHUV, Lausanne
Universitätsklinik für Kinderheilkunde, Bern
Kinderspital - Luzerner Kantonsspital, Luzern
Universitätskinderklinik beider Basel (UKBB), Basel
Hôpitaux Universitaires de Genève ( More ...
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 25.04.2023 yes
2022-02127 An exploratory study on autoantibodies in cancer patients – IOSI-IRB-001 study personal data/biological material monocentric Dr. med. Ilaria Colombo Istituto Oncologico della Svizzera Italiana Istituto Oncologico della Svizzera Italiana, Bellinzona
Comitato etico cantonale Ticino 25.01.2023
2022-02126 An Open-label, Dose Escalation, Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of TAK-676 as a Single Agent and in Combination With Pembrolizumab in Adult More ... clinical trial drugs phase 1 multicentric C Prof. Dr. med. Martin Berger Takeda Development Center Americas, Inc. (TDC Americas) Universitätsklinik für Medizinische Onkologie, Inselspital, Bern
Hôpitaux Universitaires de Genève, Geneva
Kantonsspital St.Gallen, Klinik für med. Onkologie & Hämatologie, St.Gallen
Centre Hospitalie More ...
Kantonale Ethikkommission Bern Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) 13.07.2023
2022-02125 Intraoperative neurophysiological markers to predict outcome in hemifacial spasm personal data/biological material monocentric Prof. Dr. Med. Kathleen Seidel Department of Neurosurgery, Inselspital Department of Neurosurgery, University Hospital Bern, Inselspital, Bern
Kantonale Ethikkommission Bern 06.04.2023 Study has ended
2022-02124 Sleep disordered breathing in children and adolescents with obesity non clinical, involving persons monocentric A Dre Virginie Bayon CHUV - CIRS - BH 06 CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 26.01.2023 yes
2022-02123 Cancer du sein et CAFs (cancer associated fibroblasts) : identification de marqueurs de surface prédictifs de la réponse à la chimiothérapie néoadjuvante personal data/biological material monocentric Dr Loïc Lelièvre Fondation pour le perfectionnement et la recherche en gynécologie et obstétrique CHUV/UNIL, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 23.03.2023
2022-02122 Harnessing neoantigen reactive CD4+ T cells for adoptive T cell therapy in melanoma non clinical, involving persons monocentric A Dr Assma BEN AISSA HUG HUG, geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 22.04.2024
2022-02121 Bleeding of unknown cause, insight into a multifactorial bleeding disorder: a Swiss case-control study non clinical, involving persons multicentric A Dr Alessandro Casini University Hospitals of Geneva, Geneva
Inselspital, Bern
Centre for Laboratory Medicine, St Gallen
Ente Ospedaliero Cantonale, Bellinzona
Clinica Moncucco, Lugano
Centre Hospitalier Universitaire Vaud More ...
Commission Cantonale d'éthique de la recherche Genève (CCER) Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cant More ... 01.02.2023
2022-02120 Effect of heated saline in duration of cervical ripening in women having labor induction with cervical balloon: a randomized controlled study clinical trial other clinical trials monocentric A Dr. Valeria LOMBARDI FÄH Hôpitaux Universitaires de Genève Hôpitaux Universitaires de Genève, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 17.04.2023
2022-02119 Mechanisms of type 1 diabetes endophenotypes, by cluster analysis non clinical, involving persons monocentric A Prof. Valérie Schwitzgebel Hôpitaux Universitaire de Genève HUG, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 17.01.2023 yes
2022-02118 Optimized post mortem, multi-scale imaging and transcriptomic analysis of the human thalamus and cortex deceased persons monocentric Prof. Andras Jakab University of Zürich University Children's Hospital Zürich / University of Zürich, Zürich
Kantonale Ethikkommission Zürich 27.01.2023
2022-02116 Introduction of a documentation protocol for Rezum water therapy of the prostate and analysis of practice patterns via retrospective application in a multiuser high-volume center. personal data/biological material monocentric Prof. Dr. Christian Wetterauer University Hospital Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 04.01.2023
2022-02115 20210144 - A Phase 3, Randomized, 24-week, Placebo-controlled, Double-blind Study to Assess the Efficacy, Safety, and Tolerability of Rocatinlimab (AMG 451) in Combination With Topical Corticosteroids More ... clinical trial drugs phase 3 multicentric C Prof. Dr. med. Antonio Cozzio Amgen Switzerland AG Kantonsspital Sankt Gallen, Sankt Gallen
Inselspital Bern, Bern
Hopitaux Universitaires de Geneve, Geneve
Centre Hospitalier Universitaire Vaudois, Lausanne
Universitätsspital Zürich, Zuerich
Ethikkommission Ostschweiz (EKOS) Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève More ... 15.05.2023
2022-02114 Measured values of clotting times and coagulation factors in patients treated with asparaginase for acute lymphoblastic leukemia personal data/biological material monocentric Dr Vasiliki Papadopoulou CHUV - Oncologie CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 12.12.2022 Study has ended
2022-02113 LOST DIAGNOSES? EINE UNTERSUCHUNG ZU ADHS-DIAGNOSEN BEI PERSONEN MIT EINER STRAFRECHTLICH ANGEORDNETEN THERAPEUTISCHEN MASSNAHME. personal data/biological material monocentric Prof. Dr. med. Michael Liebrenz Forensisch-Psychiatrischer Dienst, Universität Bern Forensisch-Psychiatrischer Dienst, Universität Bern, Bern
Kantonale Ethikkommission Bern 24.02.2023