| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-00296 | A Phase 3, Randomized, Open-Label Study of Axatilimab Versus Best Available Therapy in Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. Jakob Passweg | Incyte Corporation |
University Hospital Basel / Universitätsspital Basel, Hematology Division ,Petersgraben 4, CH-4031, Basel HUG - Hôpitaux Universitaires de Genève, Geneva University Hospital Zürich / Universitätsspita More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 03.07.2025 | yes | Study has ended | |
| 2025-00295 | Effects of heat application and percussion therapy on masseter muscle stiffness measured with ultrasound shear wave elastography | clinical trial | other clinical trials | monocentric | A | Dr. Dr. med dent Nenad Lukic | Universität Zürich |
Zentrum für Zahnmedizin, Zürich |
Kantonale Ethikkommission Zürich | 18.07.2025 | |||||
| 2025-00294 | Hypothermic oxygenated perfusion (HOPE) against cancer recurrence in HCC liver transplantation - International multicentre parallel group interventional RCT | clinical trial | transplantation | multicentric | A | Prof. Dr. Andreas Kremer | Clarunis |
Universitätsspital Zürich, Zürich Hopitaux Universitaire de Genève, Genève |
Kantonale Ethikkommission Zürich | Commission Cantonale d'éthique de la recherche Genève (CCER) | 29.04.2025 | ||||
| 2025-00293 | 20210181 - A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mell More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Katharina Timper | Amgen Inc. |
Universitätsspital Basel, Basel Hôpitaux Universitaires de Genève, Genève HOCH Health Ostschweiz, Kantonsspital St. Gallen, St. Gallen Stoffwechselzentrum St. Gallen, St. Gallen Universitätsspital Zür More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 03.04.2025 | |||
| 2025-00291 | Überlebenszeit und Prädiktoren bei geriatrischen Patienten (>90 Jahre) nach Schrittmacherimplantation (Masterarbeit) | deceased persons | monocentric | Professor Beat Schär | Universitätspital Basel |
Universitätspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.02.2025 | |||||||
| 2025-00289 | A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Volixibat in the Treatment of Cholestatic Pruritus in Patients with Primary Biliary Cholangitis (VANTAGE) | clinical trial | drugs | phase 2 | multicentric | C | Prof. Andreas Kremer | Mirum Pharmaceuticals, Inc. |
Universitätsspital Zürich, Klinik für Gastroenterologie und Hepatologie, Zürich Servizio di Gastroenterologia ed Epatologia, Ente Ospedaliero Cantonale, Ospedale Civico, Lugano |
Kantonale Ethikkommission Zürich | Comitato etico cantonale Ticino | 27.05.2025 | |||
| 2025-00288 | Screening for term preeclampsia in Switzerland | non clinical, involving persons | multicentric | A | Prof. Beatrcie Mosimann | Universitätsspital Basel |
University Hospital Basel,, 4031 Basel Universitätsspital für Frauenheilkunde Inselspital Bern, 3010 Bern Luzerner Kantonsspital, 6000 Luzern 16 Kantonsspital Baden, 5404 Baden Bürgerspital Solothurn, More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) | 31.10.2025 | |||||
| 2025-00287 | Carotid intima media thickness (cIMT) measurement with high-resolution ultrasound probes in children | non clinical, involving persons | monocentric | A | PD Dr. med. Stephan Wälti | Kantonsspital St. Gallen / Ostschweizer Kinderspital |
Kantonsspital St. Gallen und Ostschweizer Kinderspital, Klinik für Radiologie und Nuklearmedizin, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 28.05.2025 | yes | |||||
| 2025-00286 | Thyroidectomy for Graves' Disease and Amiodarone-induced Thyrotoxicosis: is it still necessary to achieve a preoperative euthyroid state? A retrospective multicenter study | personal data/biological material | multicentric | Dr. Andrea Goldmann | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur Bern Universitätsspital, Bern Kantonsspital St. Gallen, St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 09.05.2025 | ||||||
| 2025-00285 | Création d'un modèle d'anévrisme sacculaire sur placenta humain pour l'entrainement hybride endovasculaire et neurochirurgical. | personal data/biological material | monocentric | Dr Julien Haemmerli | Geneva university hospitals |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 12.03.2025 | |||||||
| 2025-00284 | Estimation of Pre-Post Changes Induced by Transcutaneous Tibial Nerve Stimulation (TTNS) Treatment in Patients with Neuro-Urological Complaints: A Pre-Post Intervention Study in a Rehabilitation Centr More ... | non clinical, involving persons | monocentric | A | Clare Maguire | Fachliche Leitung Physiotherapie & REHAB Projektverantwortliche SwiSCI |
Rehab Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.04.2025 | ||||||
| 2025-00283 | Impact of Multimodal versus Opioid-Only Anesthesia on Short Term Quality of Recovery after Major Surgery: A Randomized Prospective Single-Center Superiority Trial | clinical trial | other clinical trials | monocentric | A | PD Dr. med. Dominique Engel | Inselspital Bern |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 08.05.2025 | Study has ended | ||||
| 2025-00282 | To Evaluate the Effectiveness of an Interprofessional, Collaborative Approach to the Treatment of Spasticity comprising botulinum toxin & non-pharmacological post-injection therapy. A study protocol o More ... | clinical trial | other clinical trials | monocentric | A | PhD Clare Maguire | REHAB Basel AG |
REHAB Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.07.2025 | |||||
| 2025-00280 | Early evaluation of the low anterior resection syndrome after sphincter sparing rectal cancer surgery and prompt treatment: a retrospective study. | personal data/biological material | monocentric | Prof Michel Adamina | HFR Fribourg Cantonal Hospital: HFR Fribourg Hopital cantonal |
HFR Fribourg, Villars sur Glane |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 25.03.2025 | |||||||
| 2025-00277 | Why always think big if a simple solution can be a good first option? A literature review and three case reports on the reconstruction of heel soft tissue defects. | personal data/biological material | monocentric | Yves Harder | CHUV - Chirurgie plastique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.02.2025 | Study has ended | ||||||
| 2025-00276 | Ex-vivo validation of a new arthrometer to measure the First Ray Instability (FRI) of the foot | deceased persons | monocentric | Dr. Florent Moissenet | Université de Genève |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 22.07.2025 | |||||||
| 2025-00275 | Neutrophil-to-Lymphocyte Ratio for Diagnosis of Shoulder prosthesis infection | personal data/biological material | monocentric | Dr. med. Carol Strahm | HOCH Kantonsspital St. Gallen |
HOCH Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 20.02.2025 | |||||||
| 2025-00274 | Mortality, re-fracture and institutionalization rates of frail osteoporosis patients after acute hospitalization: an observational study | non clinical, involving persons | monocentric | A | Dr. med. Gregor Freystätter | Stadtspital Waid Zürich |
Stadtspital Waid, Zürich |
Kantonale Ethikkommission Zürich | 06.06.2025 | ||||||
| 2025-00273 |
SArcoma Surgery with Vacuum Enhanced wound treatment - A randomized controlled trial to evaluate the wound management in sarcoma surgery |
clinical trial | other clinical trials | monocentric | A | Dr. Alexander Wilhelm | Clarunis - Universitäres Bauchzentrum Basel |
Clarunis - Universitäres Bauchzentrum Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.04.2025 | |||||
| 2025-00272 | Long-term Extension Study for Participants with Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) in JNJ-81201887 Parent Clinical Studies | non clinical, involving persons | monocentric | B | Prof. Martin Zinkernagel | Janssen-Cilag International N.V. |
INSELSPITAL Universitatsspital Bern, Bern |
Kantonale Ethikkommission Bern | 07.07.2025 | ||||||