| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-01693 | FENTALOGS - Analysis of hair samples for their opioid content | non clinical, involving persons | multicentric | A | Tina Maria Binz | Universität Zürich |
Universtität Zürich, Zürich Universitäts-Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 18.11.2022 | yes | ||||
| 2022-01692 | Integrating hospital data for monitoring the SARS-CoV-2 epidemic in near real-time | personal data/biological material | monocentric | Guido Beldi | Institute of Social and Preventive Medicine (ISPM) |
Inselgruppe AG, Bern |
Kantonale Ethikkommission Bern | 11.10.2022 | |||||||
| 2022-01691 | Structured shared decision making for patients undergoing elective surgical or transcatheter aortic valve replacement (TOGETHER): A randomized-controlled trial | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Thomas Pilgrim | Insel Gruppe AG |
Insel Gruppe AG, 3010 Bern |
Kantonale Ethikkommission Bern | 03.02.2023 | |||||
| 2022-01688 | Extracellular Vesicle Surface Markers In Acute Cerebrovascular Syndromes | non clinical, involving persons | monocentric | A | PD Dr Med Carlo Cereda | Stroke Center, Neurocenter of Southern Switzerland |
Stroke Center, Neurocenter of Southern Switzerland, Lugano |
Comitato etico cantonale Ticino | 18.11.2022 | ||||||
| 2022-01687 | A Phase I/II study of brigatinib in pediatric and young adult patients with ALK+ Anaplastic Large Cell Lymphoma, Inflammatory Myofibroblastic Tumors or other solid tumors - the BrigaPED study | clinical trial | drugs | phase 1/2 | monocentric | C | Dr. med. / Manuel / Diezi | Princess Máxima Center for Pediatric Oncology |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.03.2023 | yes | |||
| 2022-01686 | A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC and Lenalidomide (Tec-DR) and Talquetamab in Combination with Daratumumab SC and Lenalidomide (Tal-DR) versus Daratu More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Michael Baumann | Janssen-Cilag International N.V. |
Kantonsspital St. Gallen, St. Gallen Inselspital Bern, Bern |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Bern | 06.07.2023 | |||
| 2022-01684 | Anhydroglucitol as a measure of the functional beta-cell mass in children with type 1 diabetes – pilot study | non clinical, involving persons | monocentric | A | Dr. Philippe Klee | University Hospitals of Geneva |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 31.10.2022 | yes | |||||
| 2022-01682 | Gastric point-of-care sonography with focus on gastric emptying time in patients with traumatic injuries. A prospective observational study | non clinical, involving persons | monocentric | A | Dr. med. Roman Meierhans | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 28.10.2022 | ||||||
| 2022-01681 | Investigator-initiierte, retrospektive, single-center Studie zur Entwicklung eines Frühwarnsystems für das Erkennen einer Verschlechterung von Patienten eines Akutspitals | personal data/biological material | monocentric | Prof. Dr. med. Jens Eckstein | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.10.2022 | |||||||
| 2022-01679 | International, multicenter, prospective registry to collect data on patients undergoing segmental mandibular defect reconstruction (SMDR) following oral squamous cell carcinoma (OSCC) resection | non clinical, involving persons | monocentric | A | PD Dr. Florian Thieringer | AO Foundation |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.11.2022 | ||||||
| 2022-01678 | Swiss Personalized Oncology National Data Stream (SPO-NDS) – In-depth tumor profiling in patients with advanced malignancies | non clinical, involving persons | multicentric | A | Prof. Dr. Andreas Wicki | Department of Medical Oncology and Haematology Clinic of the University of Zurich |
University Hospital Zürich, Zürich Inselspital Bern, Bern Universitätsspital Basel, Basel Kantonsspital Baselland, Liestal Hôpiteaux Universitaires Genève HUG, Genève Centre Hospitalier Universitaire More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... | 10.08.2023 | |||||
| 2022-01677 | ANALYSIS OF GROWTH FACTORS RELEASE FROM PLATELET-RICH FIBRIN EXUDATE PRF-EX) COMPARED WITH CONCENTRATED LIQUID PLATELET-RICH FIBRIN (C-PRF) | non clinical, involving persons | monocentric | A | Dr. Patrick Schmidlin | University of Zurich |
Universität Zürich Zentrum für Zahnmedizin Klinik für Zahnerhaltung und Präventivzahnmedizin, Zurich |
Kantonale Ethikkommission Zürich | 08.02.2023 | ||||||
| 2022-01676 | Secondary sclerosing cholangitis in severely ill COVID-19 patients – a retrospective multicenter analysis | personal data/biological material | multicentric | PD Dr. med. Christoph Jüngst | Klinik für Gastroenterologie und Hepatologie Universitätsspital Zürich |
Klinik für Gastroenterologie und Hepatologie, Unviersitätsspital Zürich, Zürich Gastroenterologie/Hepatologie, Luzerner Kantonsspital, Luzern astroenterologie/Hepatologie, Kantonsspital St. Gallen, St More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.10.2022 | ||||||
| 2022-01674 | Interdisziplinäres Management von PatientInnen mit lokal fortgeschrittenem, nicht-kleinzelligem Bronchialkarzinom (NSCLC) Stadium IIIA-C. | personal data/biological material | multicentric | Prof. Markus Jörger | Kantonsspital St. Gallen |
Kantonsspital, St. Gallen Kantonsspital Frauenfeld, Frauenfeld Kantonsspital Graubünden, Chur |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 10.11.2022 | ||||||
| 2022-01673 | A Phase 3 Study Evaluating the Pharmacokinetics, Safety, and Tolerability of VX‑121/Tezacaftor/Deutivacaftor Triple Combination Therapy in Cystic Fibrosis Subjects 1 Through 11 Years of Age | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. Alexander Möller | Vertex Pharmaceuticals Germany GmbH |
Universitäts-Kinderspital, Zürich Kinderklinik Inselspital, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 29.11.2022 | yes | ||
| 2022-01672 | Correlating the optically acquired 3D shape of the human dorsal surface with the corresponding radiographs of the scoliotic spine | clinical trial | other clinical trials | monocentric | A | Prof. Dr. William Taylor | ETH Zurich |
HEST/IfB, ETH Zurich, Zurich |
Kantonale Ethikkommission Zürich | 22.11.2022 | yes | ||||
| 2022-01671 | Linking intelligence with verbal learning and memory in children with epilepsy | personal data/biological material | monocentric | Prof. Dr. med. Georgia Ramantani | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 11.10.2022 | |||||||
| 2022-01670 | App-based monitoring of cigarette consumption during the smoking cessation phase to define quitting trajectories and increase motivation (SMOKEPROFILE-Study) | clinical trial | other clinical trials | monocentric | A | PD Dr. Florent Baty | KSSG |
KSSG, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 05.01.2023 | |||||
| 2022-01669 | The incidence of penetration of subtalar facette in lateral lengthening calcaneal osteoto-mies – The influence on the clinical outcome | non clinical, involving persons | monocentric | A | Dr. med. dipl. Phys. Arnd Viehöfer | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 28.10.2022 | ||||||
| 2022-01668 | In situ study of the human-specific oncogene POU5F1B | non clinical, involving persons | monocentric | A | PD Dr Marc-Olivier Sauvain | RHNe |
RHNe, Neuchatel |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 15.11.2022 | ||||||