| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-02590 | Role of Postoperative Antibiotic Prophylaxis after Osteosynthesis of the Midface | personal data/biological material | monocentric | PD Dr.med. Dr. med. dent. Maximilian Wagner |
Klinik für Mund-, Kiefer- und Gesichtschirurgie, Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.04.2025 | ||||||||
| 2024-02586 | L’ostéogénèse imparfaite : aspects cliniques, biologiques, génétiques et radiologiques | personal data/biological material | monocentric | Dr Elena Gonzalez Rodriguez | CHUV - DAL - Rhumatologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.01.2025 | |||||||
| 2024-02585 |
Understanding the mechanisms underlying Functional Neurological Disorder: agency and multisensorial integration |
non clinical, involving persons | monocentric | A | Prof. Dr. Med. Selma Aybek | Université de Fribourg |
Université de Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.03.2025 | ||||||
| 2024-02584 | Correlations between vitreous, aqueous and/or serum/plasma innate immune system biomarkers and metabolic markers in patients with different severity categories of age-related macular degeneration and More ... | personal data/biological material | monocentric | Prof. Dr. med. Justus G. Garweg | Berner Augenklinik |
Berner Augenklinik, Bern |
Kantonale Ethikkommission Bern | 18.02.2025 | |||||||
| 2024-02581 | TRI0386 - Identification of a SomaScan proteomic disease signature for Sjogren’s disease (SjD) and sicca | personal data/biological material | monocentric | Dr. Rainer Hillenbrand | Novartis Pharma AG |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.01.2025 | |||||||
| 2024-02577 | C4391024/AN INTERVENTIONAL, OPEN-LABEL, RANDOMIZED, MULTICENTER PHASE 3 STUDY OF PF-07220060 PLUS LETROZOLE COMPARED TO CDK4/6 INHIBITOR PLUS LETROZOLE IN PARTICIPANTS OVER 18 YEARS OF AGE WITH HORMON More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Razvan Andrei Popescu | Pfizer Inc. |
Tumor Zentrum Aarau, Aarau Inselspital, Universitätsspital Bern, Bern Kantonsspital Baden AG, Baden Onkologiezentrum Kantonsspital Olten, Olten Universitätsspital Basel, Basel Kantonsspital Baselland, More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 20.03.2025 | |||
| 2024-02576 | Evaluation of the implementation of a CMV cell-mediated immune assay in the routine clinical practice for the prevention of CMV infection in CMV-seropositive kidney transplant recipients | personal data/biological material | monocentric | Oriol Manuel | CHUV - Maladies infectieuses |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 25.03.2025 | |||||||
| 2024-02574 |
Registry study on online adaptive radiotherapy with the Ethos linear accelerator - ART Registry Study Registerstudie zur online adaptiven Radiotherapie mit dem Ethos-Linearbeschleuniger – ART Registe More ... |
personal data/biological material | monocentric | Dr. med. Jonathan Hollmann | Klinik für Strahlentherapie und Radioonkologie, Universitätsspital Basel |
Universitätsspital Basel, Klinik für Strahlentherapie und Radioonkologie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.01.2025 | |||||||
| 2024-02572 | PSMA-PET/CT for Unfavorable Intermediate-Risk Prostate Cancer: Standard Practice or Premature Hype? | personal data/biological material | monocentric | Dr. med. Lukas Prause | Dept. of Urology |
Dept. of Urology Cantonal Hospital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.01.2025 | |||||||
| 2024-02570 | YounG AsthMa E-health: Utilisation des outils numériques dans le soutien à l’éducation thérapeutique des enfants et des adolescent·e·s atteints d’asthme (GAME) | non clinical, involving persons | monocentric | A | Prof HES Associé Mark Marston | Haute École de la Santé La Source |
Institut et Haute École de la Santé La Source, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.02.2025 | yes | |||||
| 2024-02568 | A monocentric, randomized, double-blind study to assess the feasibility of conducting a full-scale randomized controlled trial (RCT) assessing the effect of carbidopa/levodopa ratio on orthostatic hyp More ... | clinical trial | drugs | phase 1/2 | monocentric | C | Dr Julien Bally | CHUV - Neurologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 19.02.2025 | ||||
| 2024-02565 | Performance of VENTANA MET (SP44) RxDx Assay with OptiView DAB IHC Detection on the BenchMark ULTRA Instrument as a Diagnostic Device for the Assessment of MET Status of Locally Advanced or Metastatic More ... | personal data/biological material | multicentric | Prof. Dr. med Sacha Rothschild | AstraZeneca AB |
Kantonsspital Baden, Onkologie und Hämatologie, Im Ergel 1, 5404 Baden, Baden Stadtspital Zürich Triemli, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 28.03.2025 | ||||||
| 2024-02564 | Vaccine skepticism in Switzerland – Did the COVID-19 pandemic influence the way the Swiss population perceives vaccines? | personal data/biological material | monocentric | PD Dr. med. Esther Künzli | Swiss TPH |
Swiss TPH, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.01.2025 | |||||||
| 2024-02561 | Optimised kangoroo care to support breastfeeding and healthy microbiome acquisition in very preterm infants (MINI-KAB) - a substudy of the multicenre, parallel cluster randomised NeoDeco study | non clinical, involving persons | multicentric | A | Dr. Kerstin Jost | University Children’s Hospital Basel (UKBB) |
University Children’s Hospital Basel (UKBB), Basel Universitätsspital Zürich Klinik für Neonatologie, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 14.02.2025 | yes | ||||
| 2024-02558 | Exploration of thyroid cancers microenvironment on metastasis and tumor aggressiveness | personal data/biological material | monocentric | François Gorostidi | CHUV - ORH - Chirurgie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.01.2025 | |||||||
| 2024-02557 | Gastrite auto-immune : épidémiologie, analyse sérologique et impact thérapeutique. Rétrospective sur 10 ans dans un centre tertiaire suisse. | personal data/biological material | monocentric | Dr Maxime Ringwald | CHUV - Immunologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.01.2025 | |||||||
| 2024-02555 | REGISTER-BASED, OBSERVATIONAL, STUDY ASSESSING THE TREATMENT SEQUENCING AND CLINICAL OUTCOMES OF PATIENTS WITH MELANOMA TREATED WITH SYSTEMIC THERAPIES IN THE REAL WORLD SETTING IN SWITZERLAND | personal data/biological material | monocentric | PD Dr. med. Joanna Mangana | Bristol Myers Sqibb |
Dermatology, University Hospital Zürich, Zurich |
Kantonale Ethikkommission Zürich | 29.04.2025 | |||||||
| 2024-02553 | Évaluation non invasive de la fonction microvasculaire coronaire chez les patients présentant une dissection artérielle coronarienne spontanée | personal data/biological material | monocentric | Dr. Quentin Liabot | CHUV - Cardiologie |
CHUV, Service de Cardiologie, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.01.2025 | |||||||
| 2024-02552 | Effect of the menstrual cycle on endurance exercise cardiovascular and cardiorespiratory physiology | non clinical, involving persons | monocentric | A | MD Aaron L. Baggish | UNIL - FBM - ISSUL |
University of Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.02.2025 | ||||||
| 2024-02550 | Assessments of Metabolic Responses to Acute Oral Administration of Sucrose, Glucose, and Fructose in Healthy Humans | clinical trial | other clinical trials | monocentric | A | PD Dr. Anne Christin Meyer-Gerspach | St. Clara Research Ltd. |
St. Clara Research Ltd., Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.01.2025 | |||||