BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2022-00697 Glycan-mediated protein degradation mechanism for new therapeutic strategies personal data/biological material monocentric Dr. Jonathan Back GlycoEra AG GlycoEra AG, Schlieren
Kantonale Ethikkommission Zürich 17.05.2022
2022-00696 Gait disturbances in patients with multiple sclerosis – is multiple sclerosis harboring pulse wave encephalopathy underlying normal pressure hydrocephalus? personal data/biological material monocentric PD Dr. med. Lennart Stieglitz University Hospital of Zurich, Department of Neurosurgery University Hospital of Zurich, Zurich
Kantonale Ethikkommission Zürich 22.07.2022
2022-00694 Choice of Anaesthetic Inductor for Rapid Sequence Induction in a Swiss Prehospital Medical Unit – Protocol for a Retrospective Cohort Study personal data/biological material monocentric Dr med. Laurent Suppan HUG HUG, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 17.05.2022
2022-00691 Adjuvant encorafenib & binimetinib vs. placebo in fully resected stage IIB/C BRAF V600E/K mutated melanoma: a randomized triple-blind phase III study in collaboration with the EORTC Melanoma Group clinical trial drugs phase 3 monocentric C Prof. Dr. med. Reinhard Dummer Pierre Fabre Médicament University Hospital Zürich, Zürich
Kantonale Ethikkommission Zürich 14.06.2022
2022-00690 Mittelfristige biopsychologische Effekte assistierter Reproduktionstechniken auf die psychische Gesundheit der Eltern, die Elternschaft und die Entwicklung der Kinder non clinical, involving persons monocentric A Prof. Dr. rer. nat. Ulrike Ehlert Universität Zürich Universität Zürich, Psychologisches Institut, Zürich
Kantonale Ethikkommission Zürich 24.05.2022 yes
2022-00689 Neurodevelopmental Outcome Registry for CHIldren with complex congenital heart Disease (ORCHID) in Switzerland –
impact of necrotizing enterocolitis on outcome

Study ID Req-2019-00089 (Weiterver More ...
personal data/biological material monocentric Professor Walter Knirsch University Children's Hospital University Children's Hospital, Zurich
Kantonale Ethikkommission Zürich 28.06.2022
2022-00687 Mesures ambulatoires (traitements psychiatriques contraints dans la communauté) : étude rétrospective 2013 - 2017 personal data/biological material monocentric Dr. Morandi Stéphane Direction générale de la santé - Office du Médecin cantonal Direction générale de la santé - Office du médecin cantonal, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 08.05.2019 Study has ended
2022-00686 Post-marketing Observational Study to explore Vitex-Agnus castus extract Ze 440 in Women with Premenstrual Syndrome associated with Mastodynia and/or Menstrual Cycle Irregularities under real-life con More ... non clinical, involving persons multicentric A Dr. med. Roger Eltbogen Max Zeller Söhne AG Gynäkologie und Geburtshilfe, 4502 Solothurn
Gynäkologie und Geburtshilfe Rossmarktpl. 12, 4502 Solothurn
Aeskulp Praxis Baarerstrasse 88, 6300 Zug
Plätzli 2, 6460 Altdorf
Ärzte im Zentrum Poststr. 3, More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich 07.06.2022
2022-00685 Protocol Title: Effect of POsitive therapeutic communication on PAIN and anxiety during arterial blood gas standardized procedures in the emergency department compared with traditional communication: More ... clinical trial other clinical trials monocentric A Dr. Thomas Schmutz HFR Fribourg - Hôpital cantonal Hôpital cantonal, Fribourg
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 14.07.2022
2022-00684 Vestibular dysfunction in patients with otosclerosis affecting the inner ear non clinical, involving persons monocentric A Prof. Dr. med. C. Röösli Klinik für Ohren-, Nasen-, Hals- und Gesichtschirurgie, Zürich
Kantonale Ethikkommission Zürich 28.06.2022
2022-00682 Electrical intra-cutaneous half-sine stimulation for optimized preferential C-fiber activation in an established model of evoked pain, hyperalgesia and allodynia in humans.
A randomized, crossover, s More ...
clinical trial other clinical trials monocentric A Dr. med Tobias Schneider Department of Anesthesiology University Hospital of Basel Department Anästhesie Universitätsspital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 07.07.2022
2022-00681 Comparison of two perioperative blood pressure management strategies in patients with oncologic head and neck surgery and radial free flap reconstruction clinical trial other clinical trials monocentric A PD Dr. Dr. Thomas Gander Universitätsspital Zürich MKG USZ, Zürich
Kantonale Ethikkommission Zürich 10.05.2022
2022-00680 Clinical experiences and outcome after Extended Medial Elbow Approach (EMEA) non clinical, involving persons monocentric A Dr. Rainer Schlichtherle Klinik für Orthopädie und Traumatologie des Kantonsspital St. Gallen, St. Gallen
Ethikkommission Ostschweiz (EKOS) 15.06.2022
2022-00679 The PRe-Acclimatization auGmented extreMe Altitude eXpedition (PRAGMAX) Randomized Controlled Trial clinical trial other clinical trials multicentric A PD Dr. med. Matthias Hilty University Hospital of Zurich University Hospital Zurich, Zurich
Swiss Sportclinic, 3014 Bern
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern 26.07.2022
2022-00678 Durch Lieferengpässe erzwungene Umstellung des Substitutionsmittels von Patienten unter Opioidagonisten-Therapie (OAT). personal data/biological material monocentric Dr. Peter Felleiter Luzerner Psychiatrie Drop-in, Luzern
Ethikkommission Nordwest- und Zentralschweiz EKNZ 27.04.2022
2022-00677 ENDOSCOPIC VACUUM THERAPY FOR PATIENTS WITH UPPER GASTRO-INTESTINAL TRANSMURAL DEFECTS: A RETROSPECTIVE AND PROSPECTIVE MULTI-CENTER COHORT STUDY personal data/biological material monocentric Prof. Dr. med. Stefan Seewald Amsterdam University Medical Center Gastrozentrum Hirslanden, Zürich
Kantonale Ethikkommission Zürich 10.06.2022
2022-00676 OPTIMIZING RADIOTHERAPY PLANNING WITH PHOTON-COUNTING CT FOR HEAD AND NECK AND MEDIASTINAL MALIGNANCIES personal data/biological material monocentric PD DR. Panagiotis Balermpas University Hospital Zurich University Hospital Zurich, Zürich
Kantonale Ethikkommission Zürich 06.05.2022
2022-00675 Analysing the "Straight-Leg-Evaluation-Trauma-Test" as a rapid assessment of trauma patients in trauma bay setting personal data/biological material monocentric Dr.med. Till Berl Department of trauma Department of trauma, Zürich
Kantonale Ethikkommission Zürich 28.06.2022
2022-00674 Simulation of Fibula Reconstruction of the Mandible with CARLO deceased persons monocentric Prof. Dr. Tobias Ettl Advanced Osteotomy Tools Universitätsklinikum Regensburg, Regensburg, DE
Ethikkommission Nordwest- und Zentralschweiz EKNZ 30.05.2022
2022-00671 Combined treatment of median arcuate ligament syndrome: a 20-year single-center experience personal data/biological material monocentric Nermin Halkic CHUV CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 28.04.2022