| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-02597 | Clinical Performance Study Protocol for HTT Hybrid SNP Phasing Investigational IVD Used in Clinical Trial BP45378 | personal data/biological material | monocentric | PhD and Lead Scientist, Alexandre Fort | F. Hoffmann-La Roche Ltd |
Labcorp CLS, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 30.01.2026 | |||||||
| 2025-02596 | An AI-driven Patient Decision Aids for Cancer Prevention in Socially Disadvantaged females at birth | non clinical, involving persons | monocentric | A | Professor Marie-Anne Durand | PMU - Unisanté, University Center for Primary Care and Public Health |
PMU - Unisanté, University Center for Primary Care and Public Health, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.04.2026 | ||||||
| 2025-02595 | Proliferative Vitreoretinopathy and Other Diseased Tissue of the Retina study (PVR&ODTR) | non clinical, involving persons | monocentric | A | Prof. Dr. med. Nicolas Feltgen | Institute of Molecular and Clinical Ophthalmology Basel (IOB) |
Universitätsspital Basel, Augenklinik, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.02.2026 | ||||||
| 2025-02592 | CDJI136A12101 - A Phase I/II open-label study of DJI136, a DLL3-targeted CAR-T therapy, in adult patients with ES-SCLC | clinical trial | drugs | phase 1 | multicentric | C | Prof. Alfredo Addeo | Novartis Pharma Switzerland AG |
Hôpitaux Universitaires Genevois, Genève Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 01.04.2026 | |||
| 2025-02591 | Extended Reality (XR) in Craniofacial Surgery: Patients and Parents Perception | non clinical, involving persons | monocentric | A | Dr. habil. Dr. med. Dr. med. dent. PhD MHBA Benito K Benitez | Universitäts-Kinderspital beider Basel (UKBB) |
Universitäts-Kinderspital beider Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.02.2026 | yes | |||||
| 2025-02589 | Integrated Molecular and Clinical Profiling of Transformed Splenic Marginal Zone Lymphoma | personal data/biological material | multicentric | Dr. med. Maria Cristina Pirosa | International Extranodal Lymphoma Study Group (IELSG) |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona University Hospital Basel, Basel |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.02.2026 | ||||||
| 2025-02588 | Obesity in Adults with Congenital Heart Disease: a Sub-study from the SACHER Registry | personal data/biological material | monocentric | Dr. med. Francisco Javier Ruperti Repilado | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.01.2026 | |||||||
| 2025-02587 | CA266-0008: ROSETTARCC-208: A Phase 1/2 Open-label, Multi-center, Randomized Study of Pumitamig Alone or in Combination with Ipilimumab or Cabozantinib in Participants with Advanced Renal Cell Carci More ... | clinical trial | drugs | phase 1/2 | multicentric | C | Dr. med Tobias Peres | Bristol-Myers Squibb Services Unlimited Company |
HOCH Health Ostschweiz (Kantonsspital St. Gallen), St. Gallen Universitätsspital Zürich, Klinik für Medizinische Onkologie und Hämatologie, Zürich Kantonsspital Graubünden, Departement Innere Medizin, More ... |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Zürich | 26.02.2026 | |||
| 2025-02586 | Appropriateness of medication prescribing in nursing homes: A pre-post study to evaluate the effectiveness of a clinical pharmacology team-led, digitally supported, inter-professional intervention | clinical trial | other clinical trials | monocentric | A | Dr. med. Francesca Bedussi, Pg.Cert. | Lugano Istituti Sociali (LIS) |
Institute of Pharmacological Sciences of Southern Switzerland, Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 23.02.2026 | |||||
| 2025-02585 | Fatigue and Brain (FAB): Effects of Cognitive and Physical Fatigue on Neuromuscular and Executive Function: A Bidirectional Investigation | non clinical, involving persons | monocentric | A | M.sc. Romina Ledergerber | Department of Sport, Exercise and Health |
Department of Sport, Exercise and Health, University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.01.2026 | ||||||
| 2025-02584 | A Phase 3 Open-label Randomized Study Assessing the Efficacy and Safety of RLY-2608 + Fulvestrant Versus Capivasertib + Fulvestrant as Treatment for PIK3CA-mutant Hormone Receptor Positive, Human Epid More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Anton Oseledchyk | Relay Therapeutics, Inc. |
Universitätsspital Basel, Basel Tumor Zentrum Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.02.2026 | |||
| 2025-02581 | Prospective randomized controlled trial of outpatient versus inpatient elective laparoscopic cholecystectomy | clinical trial | other clinical trials | multicentric | A | Prof. Dr. Pascal Probst | Spital Thurgau AG |
Spital Thurgau AG, Kantonsspital Frauenfeld, Chirurgische Klinik, Frauenfeld Spital Thurgau AG, Kantonsspital Münsterlingen, Chirurgische Klinik, Münsterlingen |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Ostschweiz (EKOS) | 05.03.2026 | ||||
| 2025-02579 |
EORTC DE-ESCALATE Intermittent Androgen deprivation Therapy in the era of AR pathway inhibitors; a phase 3 pragmatic randomized trial (DE-ESCALATE) |
clinical trial | drugs | phase 3 | multicentric | A | Dr. med. Fabio Turco | EORTC |
IOSI - Istituto Oncologico della Svizzera Italiana, Bellinzona STS AG, Thun Tumor Zentrum Aargau, Aarau St. Claraspital AG, Basel Luzerner Kantonsspital, Luzern Kantonsspital Olten, Olten HUG - Hôpita More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 26.02.2026 | |||
| 2025-02578 | Exercise-Induced Pulmonary Edema (EIPE) and Cardiovascular Dynamics in Endurance Athletes: A Comparative Study of Young and Older Active Individuals | non clinical, involving persons | monocentric | A | KD Dr.med. Dovile Diktanaite | Universität Basel |
Departement für Sport, Bewegung und Gesundheit, Universität Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.03.2026 | ||||||
| 2025-02577 | Validation of the French version of the Medical Achievement Self-efficacy Scale (MASS) | non clinical, involving persons | monocentric | A | Dr. Valérie Carrard | University of Lausanne |
University of Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.02.2026 | ||||||
| 2025-02576 |
SCI 001 Terbinafine for biochemically recurrent prostate cancer (TerbinaPro) - A phase II drug-repurposing Study |
clinical trial | drugs | phase 2 | multicentric | B | PD Dr. med. Stefanie Fischer | Swiss Cancer Institute |
HOCH Health Ostschweiz, Kantonsspital St.Gallen, St.Gallen Kantonsspital Baden, Baden Luzerner Kantonsspital, Luzern Universitätsspital Basel, Basel Hôpitaux Universitaires de Genève, Genève Spital Th More ... |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico can More ... | 05.03.2026 | |||
| 2025-02575 | Spatial biology of primary and metastatic colorectal cancer | personal data/biological material | monocentric | Prof. Dr. Dr. med. Andreas Moor |
ETH Zurich, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.01.2026 | ||||||||
| 2025-02574 | Course and outcome after surgical treatment in children and adolescents with pectus excavatum | personal data/biological material | monocentric | PD Dr. med. Dr. sc. nat. Raphael Vuille-dit-Bille | Universitäts-Kinderspital beider Basel |
Kinderchirurgie, Universitätskinderspital beider Basel (UKBB), Basel-Satdt |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.01.2026 | |||||||
| 2025-02573 | FOKUSS: Familienorientierte Kompetenz und Selbstwirksamkeitsstärkung - Massgeschneidertes Empowerment für Eltern von Kindern mit ADHS | clinical trial | other clinical trials | monocentric | A | Dr. Andreas Müller | Gehirn- und Traumastiftung |
Gehirn- und Traumastiftung Graubünden, Landquart |
Kantonale Ethikkommission Zürich | 14.04.2026 | |||||
| 2025-02571 | Role of antiphospholipid antibodies in patients with carotid artery stenosis undergoing endarterectomy | personal data/biological material | monocentric | Benjamin Wagner | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.01.2026 | |||||||