| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-00403 | Operationen während Schwangerschaft bei Patientinnen mit stattgehabtem bariatrischem Eingriff: diagnostisches Vorgehen, intraoperative Befunde und perioperative Resultate | personal data/biological material | monocentric | PD Dr.med. Tarik Delko | Chirurgie Zentrum St.Anna |
Chirurgie Zentrum St. Anna, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.05.2023 | |||||||
| 2023-00402 | Pre- and perioperative risk factors for primary graft dysfunction and their impact on morbidity and mortality in lung transplant patients operated on at the Centre Universitaire Romand de Transplantat More ... | personal data/biological material | monocentric | Prof Thorsten Krueger | CHUV - Chirurgie thoracique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.03.2023 | |||||||
| 2023-00401 |
Evaluation of Clinical Outcomes of Patients Undergoing a redo-TAVI procedure; a Multicentre Prospective Observational Registry The ReTAVI Prospective Observational Registry |
non clinical, involving persons | multicentric | A | Dr. Thomas Nestelberger | IPPMed - Institute for Pharmacology and Preventive Medicine GmbH |
University Hospital of Basel, Basel, Switzerland, Basel Hôpitaux universitaires de Genève, Geneve CHUV, Centre hospitalier universitaire vaudois, Lausanne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) | 12.05.2023 | |||||
| 2023-00400 | Proof-of-concept study of remote biosignal recording and monitoring of activity levels in individuals with spinal cord injury | non clinical, involving persons | monocentric | A | KD Dr. Med. Inge Eriks-Hoogland | Swiss Paraplegic Research | ETH Zurich |
Schweizer Paraplegiker-Zentrum, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.04.2023 | ||||||
| 2023-00399 | Altersbestimmung anhand CT Bildern der medialen Clavicula – eine retrospektive Auswertung. | personal data/biological material | monocentric | Dr. Tim Fischer | Kantonsspital St. Gallen |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 02.03.2023 | |||||||
| 2023-00398 |
SAKK_LuCa_2 Retrospective and prospective registry of patients with metastatic NSCLC harboring typical and atypical EGFR mutations |
personal data/biological material | multicentric | Dr. med. Sabine Schmid | SAKK |
Inselspital Bern, Bern Seeland Cancer Center – Tumorzentrum Biel, Biel Kantonsspital Aarau, Aarau Tumor Zentrum Aarau Hirslanden Medical Center, Aarau Kantonsspital Baden, Baden, Brugg, Muri St. Clara More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 07.06.2023 | ||||||
| 2023-00397 | Continuous monitoring of Circadian Rhythms using accelerometer an CORE temperature data (CROCO): An exploratory, Single-Center, Observational Study | non clinical, involving persons | monocentric | A | Dr.sc Filipe Barata | ETH Zürich |
ETH Zürich, Zürich |
Kantonale Ethikkommission Zürich | 12.05.2023 | ||||||
| 2023-00396 | Role of prasugrel and clopidogrel inactive metabolites in modulating inhibition of platelet aggregation in the acute and post-acute phase of treatment and pharmacodynamic effects of prasugrel or clopi More ... | non clinical, involving persons | monocentric | A | Prof. Marco Valgimigli | Cardiocentro Ticino Institute, EOC, |
Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 27.07.2023 | ||||||
| 2023-00395 | Optimizing resection margins of Ewings- and Osteosarcoma through improved MRI targeting. | personal data/biological material | multicentric | Professor Andreas H. Krieg | Universitäts-Kinderspital beider Basel (UKBB) |
Universitäts-Kinderspital beider Basel UKBB, Basel Inselspital, Universitätsspital Bern, Bern Universitätsklinik Balgrist, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 12.07.2023 | ||||||
| 2023-00394 | A Phase 3, Open-label Study Evaluating the Long‑term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor Triple Combination Therapy in Cystic Fibrosis Subjects 1 Year of Age and Older | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. Alexander Möller | Vertex Pharmaceuticals Germany GmbH |
Universitäts-Kinderspital, Zürich Inselspital, Kinderklinik, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 20.06.2023 | yes | ||
| 2023-00393 | Minimally invasive replacement of aortic root, ascending aorta and hemiarch via partial upper sternotomy: a propensity-score matched comparison with full sternotomy | personal data/biological material | monocentric | Prof. Dr. med. Dr. h. c. Omer Dzemali |
Klinik für Herzchirurgie, Stadtspital Triemli Zürich, Zürich |
Kantonale Ethikkommission Zürich | 05.09.2023 | ||||||||
| 2023-00392 | A pilot study on the influence of temporo-occipital transcranial magnetic brain stimulation on aversive episodic memory performance | clinical trial | other clinical trials | monocentric | A | Dr. Ehssan Amini | Universität Basel |
University of Basel, Division of Cognitive Neurosience, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.04.2023 | |||||
| 2023-00391 | Health related quality of life in egg white allergy | non clinical, involving persons | monocentric | A | Prof. Dr. med. Peter Schmid-Grendelmeier | University of Zurich, University hospital of Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 18.07.2023 | ||||||
| 2023-00390 | Retrospective international multicenter study to validate the Iwate and Institut Mutualiste Montsouris difficulty scoring systems and to develop a novel scoring system for laparoscopic and robotic liv More ... | personal data/biological material | monocentric | Dr Gaëtan-Romain Joliat | Singapore General Hospital |
Centre hospitalier universitaire vaudois (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.06.2023 | Study has ended | ||||||
| 2023-00389 | Kniegelenksnahe Osteotomien – Eine retrospektive Datenanalyse | personal data/biological material | monocentric | Prof. Dr. Sandro Fucentese | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 14.04.2023 | |||||||
| 2023-00388 | Painless Sharp Wound Debridement with Lidocaine-23%-Tetracaine-7% Gel versus EMLA 5% Cream: a single-blind, crossover, randomised, controlled trial | clinical trial | drugs | phase 2 | monocentric | C | Prof. Dr. med. Jürg Hafner |
Dermatologische Klinik USZ, Zürich |
Kantonale Ethikkommission Zürich | 28.03.2023 | |||||
| 2023-00387 | Association between coraco-glenoid ligament anatomical variants and SLAP lesion. A magnetic resonance arthrography study. | personal data/biological material | monocentric | PD Dr. Filippo Del Grande | EOC Ospedale Regionale di Lugano - Civico |
Clinica EOC IIMSI, Lugano |
Comitato etico cantonale Ticino | 26.04.2023 | |||||||
| 2023-00386 | Evolution au long cours des dérivations du canal pancréatique par voie endoscopique | personal data/biological material | monocentric | Dr Sébastien Godat | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.09.2023 | |||||||
| 2023-00385 | A Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-861 for the Treatment of Narcolepsy Without Cataplexy (Narcolepsy Type 2) | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. Dr. med. Ramin J.Khatami | Takeda Development Center Americas, Inc. |
Center for Sleep Research and Sleep Medicine, Clinic - Barmelweid AG, Switzerland, Barmelweid Department of Neurology Schlaf-Wach-Epilepsie Zentrum Inselspital, Bern University Hospital, University of More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Comitato etico cantonale Ticino | 17.05.2023 | Study has ended | ||
| 2023-00384 | Determinanten des Belastungsempfindens an der aeroben und anaeroben Schwelle von Patienten in stationärer psychosomatischer Behandlung | personal data/biological material | monocentric | Dr. sc. med. Gavin Brupbacher | Oberwaid AG |
Oberwaid AG, St.Gallen |
Ethikkommission Ostschweiz (EKOS) | 02.03.2023 | |||||||