| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-02227 | “Epidemiology and risk factors of periprosthetic fractures after primary THA: 25-year results from an institutional arthroplasty registry” | personal data/biological material | monocentric | Dr A. Gonzalez | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 08.04.2025 | |||||||
| 2024-02226 | A PROSPECTIVE INERNATIONAL MULTICENTER OBSERVATION STUDY IN PEOPLE WITH NEW ONSET MYASTHENIA GRAVIS | non clinical, involving persons | monocentric | A | Prof. Dr. Tobias Johannes Derfuss | Universitätsspital Basel |
Departement Biomedizin, Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.12.2024 | ||||||
| 2024-02225 | COMPANION DIAGNOSTICS : Clinical Performance Study Protocol for Use of the VENTANA PD-L1 (SP263) CDx Assay: Evaluation of PD-L1 Expression Levels in Non-small Cell Lung Cancer Specimens from Phase III More ... | personal data/biological material | monocentric | Dr Olivier Venzin | Bristol Myers Squibb |
Labcorp CLS, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.11.2024 | |||||||
| 2024-02224 | Benefit of immediate postoperative MRI in pediatric brain and spine tumor surgery | personal data/biological material | monocentric | Dr. med. Katharina Lutz | Neurosurgery department, Inselspital Bern |
Neurosurgery department, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 02.12.2024 | Study has ended | ||||||
| 2024-02223 | The immediate physiological and perceptual response to blood-flow restricted strength training with eccentric loading (E-BFR): a randomised crossover study in healthy subjects | clinical trial | other clinical trials | monocentric | A | Dr. Dario Kohlbrenner | Universität Zürich |
University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 31.01.2025 | Study has ended | ||||
| 2024-02221 | The effect of fully closed-loop insulin delivery on renal oxygenation in people with type 2 diabetes and chronic kidney disease: an open-label, single-center, randomized two-arm parallel trial | clinical trial | medical devices | monocentric | A1 | Dr Heba Al-Alwan | CHUV - DFME - Endocrinologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.04.2025 | |||||
| 2024-02220 | A Multi-center, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Neurological Effects of EryDex on subjects with Ataxia Telangiectasia | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. Jana Pachlopnik Schmid, MD PhD | Quince Therapeutics S.p.A. |
University Children’s Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 17.01.2025 | yes | Study has ended | ||
| 2024-02219 | Adherence to cefepime dosing recommendations: A two-centre retrospective cohort study (Retrocef) | personal data/biological material | multicentric | Dr. med. Sarah Dräger | University Hospital Basel |
University Hospital Basel, Basel University Geriatric Medicine FELIX PLATTER, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.02.2025 | ||||||
| 2024-02218 | Prevalence, incidence, risk factors and outcomes of dysnatremia among European community dwelling older adults: prospective observational analyses of the DO-HEALTH trial | personal data/biological material | monocentric | Prof. Dr. med., DrPH Heike Annette Bischoff-Ferrari | Universität Zürich |
Universität Zürich, Zentrum Alter und Mobilität, Zürich |
Kantonale Ethikkommission Zürich | 07.02.2025 | |||||||
| 2024-02217 |
ASSESSMENT OF SPEECH UNDERSTANDING VIA BONE CONDUCTION IN NORMAL-HEARING SUBJECTS WITH BILATERALLY SIMULATED CONDUCTIVE HEARING LOSS USING WEARING OPTIONS FOR BONE CONDUCTION DEVICES |
non clinical, involving persons | monocentric | A | Dr. sc. nat. Tom Gawliczek | Department of ORL, Head and Neck Surgery Inselspital |
Audiology Department of ORL, Head and Neck Surgery Inselspital, Bern |
Kantonale Ethikkommission Bern | 06.01.2025 | Study has ended | |||||
| 2024-02216 | The International PNH Interest Group PNH Registry | non clinical, involving persons | multicentric | A | Dr. med Beatrice Drexler | International PNH Interest Group (IPIG) |
Universitätsspital Basel, Hämatologie, Basel University Hospital of Bern, Inselspital, Bern Luzerner Kantonsspital, Hämatologie, Luzern Kantonsspital Aarau, Aarau Hopitaux Universitaires de Geneve, Se More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 11.06.2025 | yes | ||||
| 2024-02215 | Epidemiology and clinical presentation of acute Parvovirus B19 infection: impact of the Covid-19 pandemic. | personal data/biological material | monocentric | Dr. Denis Comte | CHUV - Médecine interne |
University Hospital of Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.04.2025 | |||||||
| 2024-02212 | Remission duration and long-term prognosis of cluster headache | non clinical, involving persons | monocentric | A | PD Dr. Heiko Pohl | University Hospital Zurich |
University Hospital Zurich, Zürich |
Kantonale Ethikkommission Zürich | 18.02.2025 | ||||||
| 2024-02211 | Oculomotor profile in acute vestibular syndrome – value of saccades, pursuit eye movements and pupillary reflexes in differentiating central and peripheral causes - a pilot study | non clinical, involving persons | monocentric | A | Prof. Dr. med. Alexander Tarnutzer | Cantonal Hospital Baden |
Cantonal Hospital of Baden, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.04.2025 | ||||||
| 2024-02210 | Association of gut and bile microbiome and hepatic inflammation in patients with cholangitis | non clinical, involving persons | monocentric | A | PD Dr. med. Sena Blümel | University Hospital Zurich |
University Hospital Zurich, Zürich |
Kantonale Ethikkommission Zürich | 04.03.2025 | ||||||
| 2024-02209 | Antimicrobial resistance of Helicobacter pylori in Zürich | non clinical, involving persons | monocentric | A | Dr. med. Bernhard Morell | Stadtspital Zürich |
Stadtspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 07.03.2025 | ||||||
| 2024-02208 | Indikation von wachstumslenkenden Operationen und deren Einfluss auf das Gangbild bei Kindern und Jugendlichen mit orthopädischen Fehlstellungen der unteren Extremitäten | personal data/biological material | monocentric | Dr. rer. nat. Nathalie Alexander | Ostschweizer Kinderspital |
Stiftung Ostschweizer Kinderspital, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 31.10.2024 | |||||||
| 2024-02207 | CPIT565B12101: A phase Ib, open-label, ascending dose study with step-up doses to assess safety, tolerability, and pharmacokinetics of PIT565 in participants with systemic lupus erythematosus (SLE) | clinical trial | drugs | phase 1 | multicentric | C | Andrea Rubbert-Roth | Novartis Pharma Schweiz AG |
Kantonsspital St. Gallen, St Gallen Inselspital, Bern |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Bern | 19.12.2024 | |||
| 2024-02206 | Urine incontinence occurrence and sexual hormones in women with chronic spinal cord injury/disease | non clinical, involving persons | monocentric | A | Prof. Dr. med. Jürgen Pannek | Schweizer Paraplegiker-Zentrum Nottwil |
Swiss Paraplegic Centre, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.12.2024 | ||||||
| 2024-02205 | Conservative Treatment of Acute Pediatric ACL-Ruptures Following a Modified Cross-Bracing-Protocol | clinical trial | other clinical trials | monocentric | A | Dr. med. Samuel Tschudi | Universitäts Kinderspital Zürich |
Universitäts Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 01.07.2025 | yes | ||||