| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-01512 | Trajectoire des patient·e·s cirrhotiques au cours de leur dernière année de vie : aperçu d’un Centre de soins tertiaires suisse. | personal data/biological material | monocentric | Natalie Décosterd | CHUV - Gastro-entérologie |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.10.2025 | |||||||
| 2025-01511 | Application of Ropivacaine-soaked Demineralized Bone Matrix (DBX) to reduce postoperative pain after lumbar Spine Fusion – a retrospective outcome study | personal data/biological material | monocentric | Dr. med. Corsin Poltera | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 17.10.2025 | |||||||
| 2025-01510 | Studying Time-dependent changes Of small intestinal Microbiomes and Associated sub-strains – The STOMA-study | non clinical, involving persons | monocentric | A | Prof. Dr. med. Andrew Macpherson | Inselspital Bern |
Universitätsklinik für Viszerale Chirurgie und Medizin, Inselspital Bern, 3010 Bern |
Kantonale Ethikkommission Bern | 02.09.2025 | ||||||
| 2025-01508 | Safety-Sling Augmentation as a Non-Cemented Alternative: Biomechanical Comparison with Cemented Lumbar Pedicle Screw-Rod Constructs | deceased persons | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 30.09.2025 | |||||||
| 2025-01507 | Bern Intracoronary Optical Coherence Tomography and Coronary Computed Tomography Angiography Registry | non clinical, involving persons | monocentric | A | Prof. Dr. med. Dr. phil. Lorenz Räber | Bern University Hospital Inselspital |
Bern University Hospital Inselsptial, Bern |
Kantonale Ethikkommission Bern | 13.10.2025 | ||||||
| 2025-01506 | High-Frequency Bone Conduction Hearing in Middle Ear Surgery | non clinical, involving persons | monocentric | A | Prof. Dr. med. Christof Röösli | Universersity Zürich |
Klinik für ORL, Hals- und Gesichtschirurgie, Zürich |
Kantonale Ethikkommission Zürich | 07.11.2025 | ||||||
| 2025-01505 |
- Relationship between Stigma (Internalized and Enacted) and Time to Diagnosis Among Women of Reproductive Age with Endometriosis in Switzerland - Zusammenhang zwischen Stigmatisierung (internalisier More ... |
non clinical, involving persons | monocentric | A | MD Panagiotis Bakoleas | King's College London, School of Life Course & Population Sciences, Faculty of Life Sciences and Medicine |
See-Spital Horgen/ King´s College London, Zürich |
Kantonale Ethikkommission Zürich | 02.12.2025 | ||||||
| 2025-01504 | Retrospective assessment of clinicogenomic characteristics and outcomes of patients with de novo or therapy-related myeloid neoplasms. | personal data/biological material | monocentric | Prof. Dr. Steffen Böttcher | University Hospital Zurich |
University Hospital Zurich and University of Zurich, Zürich |
Kantonale Ethikkommission Zürich | 11.11.2025 | |||||||
| 2025-01503 | Gender and Age Specific Differences in Tolerability of Low-Dose Oral Minoxidil for Treatment of Pattern Hair Loss | personal data/biological material | monocentric | Prof. Dr. med. Ralph M. Trüeb | Dermatologsiche Praxis und Haarcenter Prof. Trüeb |
Dermatologische Praxis und Haarcenter prof. Trüeb, Wallisellen |
Kantonale Ethikkommission Zürich | 21.11.2025 | |||||||
| 2025-01502 | Early exercise-based rehabilitation in high-risk patients hospitalized for acute pulmonary embolism: a pragmatic multicenter randomized partially blinded superiority trial | clinical trial | other clinical trials | multicentric | A | PD Dr. med. Tobias Tritschler | Inselspital |
Inselspital, Bern Kantonsspital Aarau, Aarau Kantonsspital Baden, Baden Hôpitaux Universitaires de Genève, Genève Centre hospitalier universitaire vaudois, Lausanne Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de l More ... | 01.10.2025 | ||||
| 2025-01499 |
Minimizer Ring Implantation Versus Pouch Revision for Weight Regain After Roux-en-Y Gastric Bypass. Comparative Analysis of Pouch-Revisional Surgeries Performed at a Low-Volume Bariatric Center in Sw More ... |
personal data/biological material | monocentric | Dr. Marius Arbogast | GZO Spital Wetzikon |
GZO - Spital Wetzikon, Wetzikon |
Kantonale Ethikkommission Zürich | 07.10.2025 | |||||||
| 2025-01497 | Neck resection height in cementless short stem hip arthroplasty. A biomechanical investigation. | deceased persons | monocentric | Dr. Ivan Zderic | AO Research Institute Davos |
AO Research Institute Davos, Davos |
Kantonale Ethikkommission Zürich | 30.09.2025 | |||||||
| 2025-01496 | Neonatal Characteristics and Outcomes of Preterm Infants born in Switzerland with a Birth Weight <500g | personal data/biological material | monocentric | Dr. med. Ulla Jochumsen | Universitätsspital Zürich, Klinik für Neonatologie |
Universitätsspital Zürich, Klinik für Neonatologie, Zürich |
Kantonale Ethikkommission Zürich | 14.10.2025 | |||||||
| 2025-01495 | A Phase 3, Randomized, Double-Blinded, Double-Dummy Study Evaluating the Efficacy and Safety of Intravenous Empasiprubart Versus Intravenous Immunoglobulin in Adults With Chronic Inflammatory Demyelin More ... | clinical trial | drugs | phase 3 | monocentric | C | Agustina M. Lascano, PhD, PD | argenx BV |
Hôpitaux Universitaires Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.11.2025 | ||||
| 2025-01494 | MARS MRI characteristics of resurfaced patella in symptomatic total knee arthroplasty: A retrospective study | personal data/biological material | monocentric | Prof. Dr. med. Michael Tobias Hirschmann | Kantonsspital Baselland |
Kantonsspital Baselland, Bruderholz |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.08.2025 | |||||||
| 2025-01493 | Outcomes of fecal microbiota (REBYOTA©) Therapy in Patients with Recurrent Clostridioides difficile Infection: Real-World Data from a Single Center in Switzerland | personal data/biological material | monocentric | Prof. Michael Scharl | Universitätsspital Zürich |
Universtiätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 10.10.2025 | |||||||
| 2025-01490 | Efficacy and Safety of Anticoagulation in Traumatic Cerebral Venous Sinus Thrombosis: A Retrospective Analysis | personal data/biological material | multicentric | PD Dr. med. Levin Häni | Universitätsklinik für Neurochirurgie |
Universitätsklinik für Neurochirurgie, Bern KSA Kantonsspital Aarau, Aarau |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.08.2025 | ||||||
| 2025-01489 |
Feasibility study of flow and pressure derived leakage quantification Prospective monocentric, non-randomized pilot study with 15 patients Short title: VITAL Valve Inspection for Tightness, Asse More ... |
non clinical, involving persons | monocentric | A | Dr. Emmanuel Zimmer | ARTORG Center for Biomedical Engineering Research |
Herzchirurgie, Bern |
Kantonale Ethikkommission Bern | 04.12.2025 | ||||||
| 2025-01488 | Comparative Analysis of ECT-Induced Seizure EEG Signatures in Humans and Mice | personal data/biological material | monocentric | Prof. Dr. med. Annette Brühl | UPK Basel |
UPK Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.07.2025 | |||||||
| 2025-01487 |
CHUV- DO-Lundin-PHENIX (SAKK 70/24) Open-label phase II clinical trial to test the efficacy of the combination of trimipramine and atezolizumab with bevacizumab in patients with recurrent glioblastom More ... |
clinical trial | drugs | phase 2 | multicentric | B | Prof. Dr. med. Andreas Hottinger | CHUV |
CHUV, Lausanne Inselspital Bern, Bern Universitätsspital Basel, Basel Kantonsspital Aarau, Aarau Luzerner Kantonsspital, Luzern HFR Fribourg, Fribourg Universitätsspital Zürich, Zurich |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.10.2025 | |||