| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-01019 |
A Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Volixibat in the Treatment of Cholestatic Pruritus in Patients with Primary Sclerosing Cholangitis (VISTAS) |
clinical trial | drugs | phase 2 | monocentric | C | Prof. Dr. Dr. Andreas Kremer | Mirum Pharmaceuticals, Inc. |
UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 13.08.2024 | yes | |||
| 2024-01018 | Large language models for the identification of etiotypes in COPD | personal data/biological material | monocentric | Dr. Florent Baty | Kantonsspital St. Gallen |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 23.05.2024 | |||||||
| 2024-01016 | IntraCranial Atherosclerosis Related large-vessel occlusion treated with Urgent Stenting - a pragmatic, international, multicentre, randomized trial | clinical trial | other clinical trials | monocentric | B | Prof Dr Marios-Nikos Psychogios | Universitätsspital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.07.2024 | |||||
| 2024-01014 | Retrospektive Analyse des Outcomes nach Ileozoekalresektion bei Morbus Crohn | personal data/biological material | monocentric | Dr. Michaela Ramser | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 17.09.2024 | |||||||
| 2024-01012 | Added value of diagnostic MRI imaging for radiotherapy planning (ADMIRE) | personal data/biological material | monocentric | Professor Matthias Guckenberger | University Hospital Zurich |
Radiation Oncology, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 23.08.2024 | |||||||
| 2024-01010 | Exploring the role of the prefrontal cortex in remembering and forgetting | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Jessica Peter | Universität Bern, Klinik für Alterspsychiatrie und Psychotherapie |
Universität Bern, Klinik für Alterspsychiatrie und Psychotherapie, Bern |
Kantonale Ethikkommission Bern | 19.09.2024 | |||||
| 2024-01008 | Retrospektive Studie von Screening-Untersuchungen von Sportlerinnen und Sportler der Region St. Gallen auf EKG-Veränderungen. | personal data/biological material | monocentric | Prof. Dr. Hans Rickli, Chefarzt, Klinik für Kardiologie | Berit SportClinic |
Kantonsspital St. Gallen, Klinik für Kardiologie, 9007 St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 11.07.2024 | |||||||
| 2024-01006 | Monitoring of core body temperature with a non-invasive, wearable sensor in patients with high fever | non clinical, involving persons | monocentric | A | Prof. Dr. med. Balthasar Hug | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.07.2024 | ||||||
| 2024-01005 | Nitrous Oxide in the Treatment of Acute Suicidal Ideation | clinical trial | drugs | phase 2 | monocentric | B | Professor Dr. med. Sebastian Olbrich | Psychiatrische Universitätsklinik Zürich (PUK) |
Psychiatrische Universitätsklinik Zürich, Zürich |
Kantonale Ethikkommission Zürich | 06.08.2024 | ||||
| 2024-01004 | Charakteristika von transkulturellen Patienten mit niedriger Therapieadhärenz in den Universitären Psychiatrischen Kliniken (UPK) Basel | non clinical, involving persons | monocentric | A | Dr. med. Serena Galli | Universitäre Psychiatrische Kliniken (UPK) Basel |
Universitäre Psychiatrische Kliniken (UPK) Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.09.2024 | ||||||
| 2024-01003 | Lefleuganan quantification and penetration profiles in human healthy skin biopsies, following four weeks daily topical BAP5191 application. | personal data/biological material | monocentric | Prof. Dr. med. Alexander Navarini | Bacoba AG |
Departement Klinische Forschung - Ambulantes Studienzentrum - Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.06.2024 | Study has ended | ||||||
| 2024-01002 | TRI0373 - Serologic protective pathogen Ig antibody titer in Ianalumab-Treated participants with Sjögren’s Disease | personal data/biological material | monocentric | Isabelle Isnardi, PhD | Novartis Pharma AG - Biomedical Research |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.05.2024 | |||||||
| 2024-01001 | Humoral and cellular immune response to the adjuvanted respiratory syncytial virus (RSV) vaccine in allogeneic hematopoietic cell transplant (HCT) recipients | personal data/biological material | monocentric | Prof. Jörg Halter | Universitätsspital Basel |
Klinik für Hämatologie, Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.08.2024 | |||||||
| 2024-00999 | Prospective, monocentric study to investigate retinal resting-state activity in retinitis pigmentosa patients | non clinical, involving persons | monocentric | A | Dr Ghezzi Diego | Fondation Asile des Aveugles |
Fondation Asile des Aveugles, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.08.2024 | ||||||
| 2024-00996 | Scoliosis Property INvEstigation through clinical IMaGing (SPINE-IMG) | personal data/biological material | monocentric | Dr. Daniel Studer | University of Basel, Faculty of Medicine, BIROMED-Lab |
Universitäts-Kinderspital beider Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.06.2024 | |||||||
| 2024-00994 | Evaluation de fin de croissance des enfants nés avec des fentes faciales: Questionnaire de comparaison de la satisfaction des patients, des parents et des professionnels | non clinical, involving persons | monocentric | A | PD Dr A. S. de Buys Roessingh, MD, PhD | CHUV - DFME - Pédiatrie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.06.2024 | yes | |||||
| 2024-00993 | STREPSIS – Clinical Outcomes in Streptococcus related septic shock | personal data/biological material | monocentric | Prof. Dr. med. Sascha David | Institut für Intensivmedizin |
Institut für Intensivmedizin, Zürich |
Kantonale Ethikkommission Zürich | 06.08.2024 | |||||||
| 2024-00992 | Corticospinal Mapping of Multisensory Integration and Illusory Perception via Magnetic Resonance Imaging Techniques | non clinical, involving persons | monocentric | A | Prof. Dimitri Van De Ville | EPFL |
EPFL, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.08.2024 | ||||||
| 2024-00990 | Active Brains Plan Ahead: Zusammenspiel von Handlungsplanung und Kurzzeitgedächtnis – eine Neurostimulationsstudie | non clinical, involving persons | monocentric | A | Prof. Paul Sauseng | Department of Psychology, UZH |
University of Zürich, Zürich |
Kantonale Ethikkommission Zürich | 03.09.2024 | ||||||
| 2024-00989 |
Renal-based optimization of QUADruple therapy in patients with Heart Failure with reduced ejection fraction: a prospective, multicentre, international randomized study ReQUAD-HF trial |
clinical trial | other clinical trials | monocentric | A | Dr. med. Yakup Yakupoglu | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.08.2024 | |||||