| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-02353 | A phase II, double-blind, randomised, placebo-controlled trial to evaluate the efficacy and tolerability of ZED1227 in celiac disease subjects experiencing symptoms despite gluten-free diet | clinical trial | drugs | phase 2 | multicentric | C | PD Dr.med. Jonas Zeitz | Dr. Falk Pharma GmbH |
GastroZentrum Hirslanden, CH-8032 Zürich Inselspital Bern , Freiburgstr. 18, CH-3010 Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 09.08.2024 | |||
| 2023-02352 | Economic Burden of Pulmonary Arterial Hypertension (PAH) in Switzerland | non clinical, involving persons | multicentric | A | Dr. Yuki Tomonaga | MSD Merck Sharp & Dohme AG |
EBPI, University of Zurich, Zurich Inselspital Bern, Bern Universitätsspital Basel, Basel Hôpitaux Universitaires de Genève, Genève Centre Hospitalier Universitaire Vaudois CHUV, Lausanne Réseau Hospi More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... | 19.04.2024 | |||||
| 2023-02351 | Dissecting T cell responses to Klebsiella pneumoniae | non clinical, involving persons | monocentric | A | Dr Diego Andrey | Hopitaux Universitaires de Geneve |
Hôpitaux Universitaires de Genève (HUG), Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 22.05.2024 | ||||||
| 2023-02350 | Validation of the Basel version of the Awareness of Social Inference Test – Theory of Mind (BASIT-ToM) in patients with neurodegenerative or psychiatric disorders | non clinical, involving persons | multicentric | A | Prof. Dr. med. Marc Sollberger | University Department of Geriatric Medicine FELIX PLATTER |
Memory Clinic, University Center for Medicine of Aging FELIX PLATTER, Basel Universitäre Psychiatrische Kliniken, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.02.2024 | |||||
| 2023-02347 | Urindiagnostik bei Neugeborenen und Säuglingen auf der Notfallstation im Kinderspital Luzern | personal data/biological material | monocentric | Markus Feldkötter | Kinderspital Luzern |
Kinderspital Luzern, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.04.2024 | |||||||
| 2023-02346 | Les Ac anti-Ro52kDa dans le syndrome des anticorps anti-synthétases : facteur pronostic au diagnostic et type d’atteinte pulmonaire interstitielle | personal data/biological material | monocentric | PD Dr med Peter Jandus | Hôpitaux Universitaires de Genève |
Service d’immunologie et d’allergologie, département de Médecine, HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 18.03.2024 | |||||||
| 2023-02344 | L’épigénétique pour comprendre les modifications glycémiques sous statines, étude StatRisk | non clinical, involving persons | monocentric | A | Prof. David Nanchen | Unisanté - Département promotion de la santé et préventions |
Unisanté - Département promotion de la santé et préventions, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.05.2024 | ||||||
| 2023-02343 | Adjuvant immunotherapy with anti-PD-1 monoclonal antibody Pembrolizumab (MK-3475) versus placebo after complete resection of high-risk Stage III melanoma: A randomized, double- blind Phase 3 trial of More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. Reinhard | Merck Sharp & Dohme LLC, a Subsidiary of Merck & Co. Inc |
Dummer, Zürich Unité d'Oncodermatologie, Service de Dermatologie, Hôpitaux Universitaire de Genève, 1211 GENEVE 14 Kantonsspital St. Gallen Klinik für Onkologie/Hämatologie, 9007 St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.01.2024 | |||
| 2023-02342 |
Immunotherapy with or without upfront stereotactic radiosurgery in patients with Non-Small Cell Lung Cancer with asymptomatic brain metastases: A retrospective comparison |
personal data/biological material | multicentric | Dr. Sabine Schmid | Klinik für medizinische Onkologie, Inselspital Bern |
Klinik für Medizinische Onkologie, Inselspital Bern, Bern Medizinische Onkologie Kantonsspital Baden, Baden Medizinsiche Onkologie Kantonsspital Luzern, Luzern Klinik für Onkologie, Kantonsspital Aara More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 27.02.2024 | Study has ended | |||||
| 2023-02341 | Metagenomic analyses of Nasopharyngeal microbiota of COVID-19 patients | personal data/biological material | monocentric | Prof. Gilbert GREUB | UNIL - CHUV |
Institut de microbiologie de l'Université de Lausanne, Département des laboratoires, centre hospitalier universitaire vaudois (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.02.2024 | |||||||
| 2023-02340 | Early closure of left atrial appendage for patients with atrial fibrillation and ischemic stroke despite anticoagulation therapy | clinical trial | other clinical trials | multicentric | A | Prof. Dr. med Lorenz Räber, PhD | Insel Gruppe AG |
Insel Gruppe AG, Bern Neurozentrum, Luzerner Kantonsspital, 6000 Luzern Klinik für Neurologie, Universitätsspital Basel, 4031 Basel Hôpitaux universitaires de Genève, Genf Klinik für für Neurologie, K More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de More ... | 01.05.2024 | ||||
| 2023-02339 | Impact of transcatheter aortic valve implantation on the composition and function of the gut microbiota (Gut-TAVI) | non clinical, involving persons | monocentric | A | Dr. Caroline Chong-Nguyen | Insel Gruppe AG/ Inselspital and Bern University Hospital |
Insel Gruppe AG, Bern |
Kantonale Ethikkommission Bern | 05.03.2024 | ||||||
| 2023-02338 | Cancer Epidemiology among Individuals with Incarceration Experience: A Comprehensive Study in Geneva, Switzerland | personal data/biological material | monocentric | Prof. Elisabetta Rapiti | Geneva cancer registry, University of Geneva |
Geneva cancer registry, university of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 11.04.2024 | |||||||
| 2023-02337 | Larynx Preservation Surgery Revisited: Preliminary Results on Tailored Free-Flap Reconstructions of Laryngeal Compartments | personal data/biological material | monocentric | Dr. med. Jonas Werner | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.01.2024 | |||||||
| 2023-02334 | Anticoagulation for Stroke Prevention in Patients with Recent Episodes of Atrial Fibrillation occuring transiently with Stress | clinical trial | drugs | phase 4 | multicentric | A | Dr. med. Philipp Krisai | Population Health Research Institute |
University Hospital Basel, Basel Kantonsspital Aarau, 5001 Aarau Kantonsspital Baden, 5404 Baden Cantonal Hospital St. Gallen, St. Gallen Kantonsspital Winterthur, Winterthur |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 13.02.2024 | |||
| 2023-02332 | CAIN457C22301E1 - A multi-center, open-label extension study of subcutaneous secukinumab to evaluate the long-term safety and tolerability in polymyalgia rheumatica (PMR) | clinical trial | drugs | phase 3 | multicentric | B | Prof. Dr. med. Frauke Förger | Novartis Pharma Schweiz AG |
HOCH Health Ostschweiz, St.Gallen Universitätsspital Basel, Basel HFR, Fribourg |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.03.2024 | |||
| 2023-02329 | Circadian clockwork and the lung tumorigenesis in humans: underlying mechanisms and new avenues for diagnostics and treatment | personal data/biological material | monocentric | Dr Benoît Bédat | CMU |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 31.07.2025 | |||||||
| 2023-02327 | Conditioned open-label placebos to facilitate opioid reduction in patients with chronic noncancer pain: A randomized controlled trial | clinical trial | other clinical trials | monocentric | A | PD Dr. Cosima Locher | University Hospital Zurich | University of Zurich |
Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, Zürich |
Kantonale Ethikkommission Zürich | 26.03.2024 | |||||
| 2023-02326 | Untersuchung von Herzkatheterinterventionen in chirurgisch implantierten kardialen Shunts im Neugeborenen-/Säuglingsalter am Kinderspital Zürich – Retrospektive Datenanalyse | personal data/biological material | monocentric | Prof. Dr. med. Oliver Kretschmar | Kinderspital Zürich |
Kinderspital Zürich, 8032 Zürich |
Kantonale Ethikkommission Zürich | 12.03.2024 | |||||||
| 2023-02325 | Emergence profile duplication in single implant crowns in the esthetic zone. A randomized controlled trial comparing conventional and digital workflows. | clinical trial | other clinical trials | monocentric | A | Dr. Manrique Fonseca | Universitat Bern |
Bern, Bern |
Kantonale Ethikkommission Bern | 11.07.2024 | |||||