| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-00470 | A first-in-human, open-label, multicenter Phase I/II study to evaluate the safety and anti-tumor activity of ANV600 as single agent and in combination with pembrolizumab in participants with advanced More ... | clinical trial | drugs | phase 1/2 | multicentric | C | Prof. Dr. Dr. Markus Jörger | Anaveon AG |
HOCH Health Ostschweiz, Kantonsspital St. Gallen, St. Gallen Ente Ospedaliero Cantonale (EOC), Bellinzona |
Ethikkommission Ostschweiz (EKOS) | Comitato etico cantonale Ticino | 25.04.2024 | |||
| 2024-00468 | Study of clinical data and biomaterial from patients with Acute Myeloid Leukemia and WT1 Recombinant Protein Vaccination | personal data/biological material | monocentric | Dr. med. Stefanie Kreutmair | University of Zurich |
University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 14.05.2024 | |||||||
| 2024-00467 | Behavioural Dysfunction Questionnaire (BDQ): Data-driven adaptation of the scoring to increase the discriminatory power of the BDQ between behavioural variant frontotemporal dementia and other brain d More ... | personal data/biological material | monocentric | Prof. Dr. med. Marc Sollberger | University Department of Geriatric Medicine FELIX PLATTER |
University Center for Medicine of Aging, FELIX PLATTER, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.03.2024 | |||||||
| 2024-00466 | Randomisierte klinische Studie zum Einfluss von Atemübungen auf das Stress-Level und die Schlafqualität von schwangeren Frauen | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Daniel Surbek | Universitätsklinikum für Frauenheilkunde, Inselspital Bern |
Universitätsklinik für Frauenheilkunde, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 29.08.2024 | |||||
| 2024-00465 | Das Spektrum und die Charakteristika von akuten Nierenfunktionseinschränkungen am Universitätsspital Basel | personal data/biological material | monocentric | Prof. Dr. med. Michael Dickenmann | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.05.2024 | |||||||
| 2024-00464 | Catheter based ablations for treatment of atrial fibrillation in a swiss non tertiary center. | personal data/biological material | monocentric | PD Dr. med. Alexander Breitenstein | Kantonsspital Baden |
Kantonsspital Baden, Baden-Dättwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.04.2024 | |||||||
| 2024-00463 | Validierung eines schweizerdeutschen Kindersprachtests | non clinical, involving persons | multicentric | A | M Sc Christoph Schmid | Inselspital Bern |
Inselspital Bern, Bern Universitätsspital Basel, Basel Kantonsspital Luzern, Luzern Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 12.07.2024 | yes | Study has ended | |||
| 2024-00461 | Development and Assessment of Novel Multiparametric MRI Methods for the Human Skeletal Muscle | non clinical, involving persons | monocentric | A | Dr Francesco Santini | University Hospital of Basel |
University Hospital of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.04.2024 | ||||||
| 2024-00460 | Vergleich der Therapieziele sowie Patient:innen- und Therapiecharakteristiken zweier multidirektionaler, gewichtsentlastender, overground Gehsysteme | personal data/biological material | monocentric | Prof. Dr. Hubertus van Hedel | Swiss Children's Rehab, University Children's Hospital Zurich |
Swiss Children's Rehab, University Children's Hospital Zurich, Affoltern am Albis |
Kantonale Ethikkommission Zürich | 30.04.2024 | |||||||
| 2024-00459 | Identification of genetic modifiers for disease severity in patients with hereditary angioedema (HAE) | personal data/biological material | monocentric | Prof. Dr. Sven Cichon | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.03.2024 | |||||||
| 2024-00458 | Can endomedullary nailing restore hip geometry in geriatric patients? – a retrospective case series | personal data/biological material | monocentric | Dr. med. Method Kabelitz | Stadtspital Zürich |
Clinic for Orthopaedics, Hand Surgery and Trauma Surgery, Stadtspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 30.04.2024 | |||||||
| 2024-00457 | Impact of Hybrid Closed-Loop insulin delivery on quality of life, trust and metabolic control in children and adolescents with type 1 diabetes in daily life. | non clinical, involving persons | monocentric | A | PD Dr. Michael Hauschild | CHUV - DFME - Endocrinologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.04.2024 | yes | |||||
| 2024-00456 | A Phase I, two parts study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple ascending doses of BAR502 in healthy subjects | clinical trial | drugs | phase 1 | monocentric | C | Dr Milko Radicioni | BAR Pharmaceuticals Srl |
CROSS Research S.A. Phase I Unit, Arzo, Switzerland |
Comitato etico cantonale Ticino | 22.05.2024 | ||||
| 2024-00455 | Mapping odour-elicited feelings onto the human brain. | non clinical, involving persons | monocentric | A | Dr. David Sander | CISA – University of Geneva |
University of Geneva, CISA, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.06.2024 | Study has ended | |||||
| 2024-00453 | Periodontal status, inflammatory and adipokine markers in patients before and after bariatric surgery: a pilot study | non clinical, involving persons | monocentric | A | Prof. Giovanni Salvi | Department |
University of Bern, Bern |
Kantonale Ethikkommission Bern | 22.05.2024 | Study has ended | |||||
| 2024-00452 | COMBINE ASPECTS: Comprehensive Observation and Modeling of Baseline Imaging and Neurological Evaluation for Advancing Stroke outcome Prediction and Evaluation using CT TechniqueS | personal data/biological material | monocentric | Dr. Dr. Tolga Daniel Dittrich | Cantonal Hospital St. Gallen |
Cantonal Hospital St. Gallen, Switzerland |
Ethikkommission Ostschweiz (EKOS) | 19.12.2024 | |||||||
| 2024-00450 | EVSia-Trial - Direct end-to-end closure vs. resection and hand-sewn / stapled anastomosis techniques for the takedown of loop ileostomy: Does the technique of anastomosis play a role in postoperative More ... | personal data/biological material | multicentric | PD Dr. med. Christian Nebiker | Klinik für Viszeralchirurgie Kantonsspital Aarau |
Klinik für Viszeralchirurgie Kantonsspital Aarau, Aarau Clarunis AG Standort Claraspital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.06.2024 | ||||||
| 2024-00447 | Nachhaltigkeit und Sicherheit des Opiatentzugsverfahrens unter Anästhesie nach der Methode ANR/Opiostop® von 2014 bis Juli 2022 - eine retrospektive Analyse | non clinical, involving persons | monocentric | A | Dr. med. Patricia Manndorff | Stiftung Opiostop |
Spitäler fmi AG, Unterseen |
Kantonale Ethikkommission Bern | 22.07.2024 | Study has ended | |||||
| 2024-00446 | Ablation with Confirmation of Colorectal Liver Metastases (ACCLAIM) Prospective Trial for Microwave Ablation as a Local Cure | non clinical, involving persons | monocentric | A | Rafael Duran, MD | CHUV - Radiodiagnostic et |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.05.2024 | ||||||
| 2024-00445 | Effekt von Sodium-Glukose-Co-Transporter-2 Inhibitoren (SGLT2-i) auf die Proteinurie, Nierenfunk-tion und Krankheitsprogression in Glomerulonephritiden (GN) und Glomerulopathien (GP) unter-schiedliche More ... | personal data/biological material | monocentric | Stephanie Damm | Abteilung Nephrologie, Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 20.08.2024 | |||||||