| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-00641 | A Phase 3, Randomized, Open-label Study of Relatlimab-nivolumab Fixeddose Combination Versus Regorafenib or Trifluridine + Tipiracil (TAS-102) for Participants with Later-lines of Metastatic Colorecta More ... | clinical trial | combination drugs/devices | phase 3 | multicentric | C | Dr. med. Razvan Popescu | Bristol-Myers Squibb International Corporation |
Privatklinikgruppe Hirslanden - Hirslanden Klinik Aarau, Aarau Universitätsspital Bern - Inselspital - Universitätsklinik für Medizinische Onkologie, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 03.11.2022 | Study has ended | ||
| 2022-00640 | Which malunion of the radius is clinically relevant | personal data/biological material | monocentric | PD Dr. med. Lisa Reissner | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 19.04.2022 | |||||||
| 2022-00639 | Characterization of the immune response in immunosuppressed patients with rheumatic diseases, including to the recombinant zoster vaccine: a prospective observational cohort study | non clinical, involving persons | multicentric | A | Pr Arnaud Didierlaurent | HUG |
Faculty of Medicine and Geneva University Hospital, Geneva Universitätsspital Basel, Basel CHUV, Lausanne |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.07.2022 | |||||
| 2022-00638 | Effects of N-Acetyl-L-Leucine on Niemann-Pick disease type C (NPC): A Phase III, randomized, placebo-controlled, double-blind, crossover study | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. med. / Tatiana / Brémòva-Ertl | IntraBio Ltd |
University Hospital Bern Inselspital, Bern |
Kantonale Ethikkommission Bern | 24.08.2022 | yes | |||
| 2022-00637 | Influence de la position du corps sur la pathophysiologie du décès dans les morts par pendaison incomplète | personal data/biological material | monocentric | Prof. Tony Fracasso | Centre universitaire romand de médecine légale |
Centre universitaire Romand de médecine légale, rue Michel-Servet n.1, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 05.10.2022 | |||||||
| 2022-00636 | A Randomized, Double-Blind, Dose Finding and Comparison Study of the Safety and Efficacy of High Doses of Eteplirsen, Preceded by an Open-Label Dose Escalation, in Patients With Duchenne Muscular Dyst More ... | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. Dirk Fischer | Sarepta Therapeutics, Inc. |
Universitäts-Kinderspital beider Basel (UKBB), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.01.2023 | yes | |||
| 2022-00635 | THE EFFECT OF BITE RAISERS ON MOLAR INTRUSION IN CHILDREN AND ADOLESCENTS: A TWO-ARMED LONGITUDINAL RANDOMIZED CONTROLLED TRIAL | clinical trial | other clinical trials | monocentric | A | Professeur Gregory Antonarakis | Division Orthodontie, Clinique de Médecine Dentaire Université de Genève |
Division d'orthodontie, Université de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.02.2023 | yes | ||||
| 2022-00634 | Use of a mechanical resuscitation device in the preclinical routine: a prospective observational study | non clinical, involving persons | monocentric | A | Dr. med. Richard Steffen | Universitätsklinik für Anästhesiologie und Schmerztherapie |
Universitätsklinik für Anästhesiologie und Schmerztherapie, Inselspital, Bern |
Kantonale Ethikkommission Bern | 02.08.2022 | ||||||
| 2022-00633 | ICU Cockpit: A platform for collecting multimodal waveform data, AI-based computational disease modelling and real-time decision support in the intensive care unit: Silent validation of ICU Cockpit So More ... | personal data/biological material | monocentric | Prof. Dr. med. Emanuela Keller | University Hospital Zurich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 26.04.2022 | |||||||
| 2022-00632 | Investigating the effect of normal frequency-band and infra-low frequency neurofeedback on functional brain connectome | clinical trial | other clinical trials | monocentric | A | PD Dr. Philipp Stämpfli | Psychiatrische Universitätsklinik Zürich |
Psychiatrische Uniklinik Zürich, Zürich |
Kantonale Ethikkommission Zürich | 11.10.2022 | |||||
| 2022-00631 | Stereotactic multiple fraction radiotherapy for non-spine bone metastases | clinical trial | other clinical trials | multicentric | A | PD Dr. med. Robert Foerster | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur Inselspital, Bern University Hospital, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 03.05.2022 | ||||
| 2022-00630 | Cross-cultural acceptability of interventions that may increase control at the end of life in patients with dementia (CONT-END WP1) | non clinical, involving persons | monocentric | A | Jan Gärtner | Department of Public Health and Primary Care (PHEG) | Leiden University Medical Center |
Palliativzentrum Hildegard, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.07.2022 | ||||||
| 2022-00629 | Combining the advantages of 3D and 2D templating of total knee arthroplasty using a new ultra-low dose CT of the knee- a comparative study of accuracy. | personal data/biological material | monocentric | Prof. Dr. med. Sandro Fucentese | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 12.04.2022 | |||||||
| 2022-00628 | CANNABIS PILOT TRIAL IN THE CANTON OF BASEL-LANDSCHAFT IN ACCORDANCE WITH THE ORDINANCE ON PILOT TRIALS UNDER THE NARCOTICS LAW (BETMPV) | non clinical, involving persons | monocentric | A | Prof. Dr. Michael Schaub | Schweizer Institut für Sucht- und Gesundheitsforschung ISGF |
Schweizer Institut für Sucht- und Gesundheitsforschung ISGF, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.05.2022 | ||||||
| 2022-00625 | Cognitive Foundations of Music | non clinical, involving persons | monocentric | A | Prof. Dr. Martin Rohrmeier | EPFL |
EPFL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.10.2022 | ||||||
| 2022-00624 | EARLY IDENTIFICATION OF VENTILATOR ASSOCIATED PNEUMONIA USING MACHINE LEARNING TECHNIQUES: A PROSPECTIVE COHORT STUDY | non clinical, involving persons | monocentric | A | Prof Dr. med. Alberto Pagnamenta | Ente Ospedaliero CAntonale |
EOC, Lugano |
Comitato etico cantonale Ticino | 03.07.2023 | ||||||
| 2022-00623 | Swiss-Austrian Very Preterm Infant Transition Study (SAVE-T Study): Transition to home: Improving outcomes of children and families | clinical trial | other clinical trials | multicentric | A | Prof. Dr. med. Beatrix Latal | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital Zürich, Zurich University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 04.10.2022 | yes | |||
| 2022-00621 | MK-1088-002: A Phase 1/Phase 2 Study to Evaluate the Safety and Tolerability of MK-1088 as Monotherapy and in Combination with Pembrolizumab in Participants with Advanced Solid Tumors | clinical trial | drugs | phase 1/2 | multicentric | C | PD Dr. med. Anastasios Stathis | Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona Kantonsspital St. Gallen, St. Gallen Kantonsspital Graubünden, Chur |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 28.06.2022 | Study has ended | ||
| 2022-00620 | Existe-t-il des éléments au diagnostic d'une sarcoïdose cardiaque qui prédisent une extinction de l'hypermétabolisme au PET-CT à 1 an de traitement immunosuppresseur ? | personal data/biological material | monocentric | Prof. Camillo Ribi | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.10.2022 | |||||||
| 2022-00619 | Novel Long Acting Injectable Antiretrovirals: Real-Life Therapeutic Drug Concentration Monitoring in Switzerland | non clinical, involving persons | multicentric | A | Prof Matthias Cavassini | CHUV |
CHUV, Lausanne HUG, Geneva |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.07.2022 | |||||