| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-02145 | Outcomes of patients on home mechanical ventilation – an observational study from a tertiary referral centre | personal data/biological material | monocentric | PD Dr. med. Esther Irene Schwarz | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 09.02.2024 | |||||||
| 2023-02144 |
Retinal markers in neuroinflammatory diseases: a prospective observational study |
non clinical, involving persons | monocentric | A | PD Dr. med. Athina Papadopoulou | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.01.2024 | ||||||
| 2023-02142 | Double-blind, Randomized, Placebo-controlled Study Evaluating the Safety and Efficacy of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) in At-risk Pregnanci More ... | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. David Baud | Janssen-Cilag International N.V. |
Centre Hospitallier CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.09.2024 | yes | |||
| 2023-02140 | Patient-Derived Organoids: Establishment of Models and Their Applications in Disease Modeling, Drug Discovery, and Personalized Medicine | personal data/biological material | monocentric | Jens Grosch | F. Hoffmann-La Roche AG |
F. Hoffmann-La Roche Ltd, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.02.2024 | |||||||
| 2023-02139 | Sentinel lymph node biopsy for cT1/2 oral cavity carcinoma: retrospective evaluation of a prospective cohort. | personal data/biological material | multicentric | Dr. med. Fabrice Savaria | Hals-Nasen-Ohrenklinik, Kantonsspital St. Gallen |
Hals-Nasen-Ohrenklinik, Kantonsspital St. Gallen, St. Gallen Hals-Nasen-Ohrenklinik, Universitätsspital Zürich, Zürich |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Zürich | 06.12.2023 | ||||||
| 2023-02138 | Early Detection of Health Deterioration in Elderly Patients after Hospitalization for Heart Failure Decompensation: A potential Role for Ambient Sensor Systems in the Patients Home | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Hugo Saner |
Solothurn Spitäler AG, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.12.2023 | ||||||
| 2023-02137 | Retrospective single-center analysis of recurrence patterns in patients with high grade gliomas after surgical resection and adjuvant radiochemotherapy. (Masterarbeit) | personal data/biological material | monocentric | Prof. Frank Zimmermann | Universitätsspital Basel |
Radioonkologie, Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.11.2023 | Study has ended | ||||||
| 2023-02136 | Relevance of ISG neutrophils in lung cancer patients receiving immunotherapy | non clinical, involving persons | monocentric | A | Professor Alfredo Addeo | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 12.02.2024 | ||||||
| 2023-02135 | Bicarbonate from arterial blood gas analysis as a predictor of sleep-related hypoventilation | personal data/biological material | monocentric | PD Dr. med. Esther Irene Schwarz | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 12.01.2024 | Study has ended | ||||||
| 2023-02133 | Outcome after hypospadias repair in children – local bacterial load with and without postoperative antibiotic prophylaxis - a pilot study | clinical trial | other clinical trials | monocentric | A | Dr. med. Martina Frech-Doerfler | UKBB |
UKBB Universitäts-Kinderspital beider Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.06.2024 | yes | ||||
| 2023-02132 |
Charakterisierung der Pathophysiologie der Wesensglieder: einarmige klinische Pilotstudie der direkten Wesensgliederdiagnose und -Therapie |
clinical trial | other clinical trials | monocentric | A | Jana Siroka | Klinik Arlesheim |
Klinik Arlesheim, Arlesheim |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.04.2024 | |||||
| 2023-02131 | CHUV-DC-0037-preReDSeL-2023: Prospective clinical study to identify secondary sentinel lymph nodes in patients with N1/N2b oral cavity or H&N skin cancers using Patent Blue V and indocyanine green dye More ... | clinical trial | drugs | n/a | monocentric | A | Prof. Christian Simon | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.02.2026 | ||||
| 2023-02129 | Up to 5-Year clinical results of a two-piece ceramic oral implant system | personal data/biological material | monocentric | Dr. Jens Tartsch | Zahnarztpraxis Dr. Tartsch |
Praxis Dr. Tartsch, Kilchberg |
Kantonale Ethikkommission Zürich | 09.01.2024 | |||||||
| 2023-02128 | Modulating emotion regulation and emotional memory with transcranial direct-current stimulation (tDCS) | clinical trial | other clinical trials | monocentric | A | Professor Ulrike Rimmele | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 15.07.2024 | |||||
| 2023-02127 | Effects of obesity on lung volumes, sleep disordered-breathing and respiratory insufficiency – a cross-sectional observational study | personal data/biological material | monocentric | PD Dr. med. Esther Irene Schwarz | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 09.01.2024 | Study has ended | ||||||
| 2023-02126 |
Resultate nach Ossikuloplastik bei Mittelohrmalformationen (Klasse 2 und 3) (Outcome of ossiculoplasty in congenital ossicular anomalies class 2 and 3) |
personal data/biological material | monocentric | Dr. med. Christoph Schlegel | Luzerner Kantonsspital |
HNO-Klinik, Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.07.2024 | |||||||
| 2023-02125 | Multi-centre Epilepsy Lesion Detection (MELD) Project: Automated detection of focal epilepsies | personal data/biological material | monocentric | Prof. Dr. med. Georgia Ramantani, PhD | Wellcome Centre for Human Neuroimaging, University College London |
Universitäts-Kinderspital, Zürich |
Kantonale Ethikkommission Zürich | 26.01.2024 | |||||||
| 2023-02124 | Studio clinico, multicentrico, retrospettivo di confronto tra metodiche di localizzazione preoperatoria di lesioni della mammella non palpabili in pazienti sottoposte a chirurgia conservativa mammaria | personal data/biological material | monocentric | Maria Luisa Gasparri Prof, MD, PhD | IRCCS Pavia |
Department of Obstetrics and Gynecology, Ente Ospedaliero Cantonale, Ospedale Regionale di Lugano, Lugano |
Comitato etico cantonale Ticino | 30.04.2024 | |||||||
| 2023-02123 | OV PRECISION: A randomized controlled Swiss trial examining the benefit of a tumor- and patient-specific cancer therapy in ovarian cancer | clinical trial | other clinical trials | multicentric | B | Prof. Dr. Viola Heinzelmann-Schwarz | Swiss GO Trial Group |
Universitätsspital Basel, Basel Inselspital Bern, Bern KS Baden, Baden Hirslanden Klinik St. Anna, Luzern Thurgau-AG, Frauenfeld HOCH Health Ostschweiz Kantonsspital St.Gallen, St. Gallen Hôpital Fri More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 14.03.2024 | ||||
| 2023-02122 | Legionella in the ICU – a retrospective observational study of clinical and laboratory values and outcome of patients with severe pneumonia attributed to Legionella pneumophila admitted to the intensi More ... | personal data/biological material | monocentric | Prof. Dr. / Sascha / David | USZ, IFI |
Institute of Intensive Care, Zurich |
Kantonale Ethikkommission Zürich | 02.02.2024 | |||||||