| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-00059 | Incidence and natural course of Arachnoid and Pineal cysts in a single centre | personal data/biological material | monocentric | PD Dr. med. Jehuda Soleman | University Hospital Basel |
Department of Neurosurgery, University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.02.2023 | Study has ended | ||||||
| 2023-00058 | Microbiological and clinical investigation of novel bacterial species using 16S rRNA gene sequencing and whole genome sequencing | personal data/biological material | monocentric | PD Dr. Daniel Goldenberger | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.02.2023 | |||||||
| 2023-00057 | Goal directed fluid removal with furosemide in intensive care patients with fluid overload: a randomised, blinded, placebo-controlled trial | clinical trial | drugs | phase 4 | monocentric | A | Dr. Jan Waskowski | Nordsjællands Hospital, University of Copenhagen |
Universitätsklinik für Intensivmedizin, Inselspital, Bern |
Kantonale Ethikkommission Bern | 12.05.2023 | ||||
| 2023-00056 | Hepatic single-cell physiology in function of lobular zone, circadian time and sex | personal data/biological material | monocentric | Prof. Dr. Felix Naef | EPFL |
EPFL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.02.2023 | |||||||
| 2023-00055 | Identification of the molecular changes leading to beta-cell dysfunction and enhanced insulin sensitivity in members of an affected family - HEREDIA-Study | non clinical, involving persons | monocentric | A | Prof. Marc Donath | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.02.2023 | yes | |||||
| 2023-00054 | Impact of a deprescribing tool on sedative hypnotics use among older patients: A cluster-randomized controlled trial in Swiss primary care (the HYPE trial) | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Stefan Neuner-Jehle |
Institute of Primary Care, Zurich |
Kantonale Ethikkommission Zürich | 04.04.2023 | ||||||
| 2023-00053 | Biomarker search for progression in multiple sclerosis (MS) | personal data/biological material | monocentric | Prof. Dr Jens Kuhle | Novartis Pharma AG - NIBR |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.01.2023 | |||||||
| 2023-00051 | Wirksamkeit des stationären suchtsensiblen Traumatherapiekonzepts S.T.A.R.K. der Klinik im Hasel | personal data/biological material | monocentric | Dr. Louisa Lorenz |
Klinik im Hasel, Gontenschwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.04.2023 | ||||||||
| 2023-00050 | MR1-restricted T cells in autoimmune conditions of the gut | non clinical, involving persons | monocentric | A | Prof. Petr Hruz | Clarunis |
Clarunis, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.02.2023 | ||||||
| 2023-00049 | High-resolution mapping of hand innervation: novel approaches at 7T MRI at Campus Biotech of Geneva in volunteers, aiming an open atlas data | non clinical, involving persons | monocentric | A | sana Boudabbous | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 27.02.2023 | ||||||
| 2023-00048 | Neurobiological underpinnings of Highly Superior Autobiographical Memory (HSAM) | non clinical, involving persons | monocentric | A | Prof. Dominique de Quervain | University of Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.02.2023 | Study has ended | |||||
| 2023-00047 | Outcome and long-term results after fenestrated and branched endovascular aortic repair (F/BEVAR) | personal data/biological material | monocentric | Dr. med. Benedikt Reutersberg | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 10.02.2023 | |||||||
| 2023-00046 | Patient reported outcomes after oncoplastic breast conserving surgery | non clinical, involving persons | monocentric | A | Dr. med. Kavitha Däster | Brust-Zentrum AG |
Brust-Zentrum AG, Zürich |
Kantonale Ethikkommission Zürich | 17.03.2023 | ||||||
| 2023-00045 | A comparative study of the use of selective digestive decontamination prophylaxis in liver transplant recipients | personal data/biological material | multicentric | Dre Hannah Wozniak |
HUG, Genève USZ, Zürich |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Zürich | 17.04.2023 | |||||||
| 2023-00044 | Überprüfung der Validität einer automatisierten SoftwareApplikation zur Erfassung der Sprunghöhe mit einem Kamerasystem zur dreidimensionalen Bewegungsanalyse | non clinical, involving persons | monocentric | A | Dr. Martin Keller | Universität Basel: Departement für Sport, Bewegung und Gesundheit |
Universität Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.02.2023 | Study has ended | |||||
| 2023-00042 | DISCOVERY OF PREDICTIVE BIOMARKERS OF RESPONSE AND/OR RESISTANCE TO ATEZOLIZUMAB + BEVACIZUMAB IN ADVANCED HCC: AN INTERNATIONAL, MULTICENTER STUDY | personal data/biological material | monocentric | PD. Dr. Anja Lachenmayer | Division of Liver Diseases, Tisch Cancer Institute Icahn School of Medicine at Mount Sinai, New York |
Department of Visceral Surgery and Medicine, Bern |
Kantonale Ethikkommission Bern | 19.06.2023 | |||||||
| 2023-00041 | A comparative assessment of the BioBiteCorrector® and Herbst appliances in the treatment of Class II malocclusion: a retrospective cohort study. | personal data/biological material | monocentric | Dr. Vasiliki Koretsi |
Klinik für Kieferorthopädie und Kinderzahnmedizin Zentrum für Zahnmedizin, Universität Zürich, Zürich |
Ethikkommission Ostschweiz (EKOS) | 20.01.2023 | ||||||||
| 2023-00040 | "Effects of lumbar lordosis and passive structures on local intervertebral pressure and pressure of adjacent segments as well as on range of motion" | deceased persons | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 10.02.2023 | |||||||
| 2023-00039 | HeadFirst | non clinical, involving persons | multicentric | A | MD/Draganski/Bogdan | CHUV - Neurologie - LREN |
CHUV-UNIL, Lausanne Universität Basel, Basel |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.07.2024 | |||||
| 2023-00037 | Prospective laboratory-based evaluation of neurological and autoinflammatory biomarkers in cognitive decline/dementia: A multicenter pilot study | non clinical, involving persons | multicentric | A | MD Pio Eugenio Fontana | Medisyn |
Clinica Moncucco, Lugano Studio Medico Chiasso G&P, Chiasso |
Comitato etico cantonale Ticino | Comitato etico cantonale Ticino | 14.05.2024 | |||||