| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-D0096 | An Open-label Randomized Phase 3 Study of Tucatinib in Combination with Trastuzumab and mFOLFOX6 versus mFOLFOX6 given with or without either Cetuximab or Bevacizumab as First-line Treatment for Subje More ... | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C1 | Dr. Ralph Fritsch | Seagen Inc., a wholly owned subsidiary of Pfizer |
Universitätsspital Zürich, Klinik für Medizinische Onkologie und Hämatologie, Zürich Kantonsspital Winterthur, Brauerstr. 15 |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 30.06.2023 | ||||
| 2022-D0094 | A Prospective, Randomized, Blinded Evaluator, Multicenter, Clinical Study to Evaluate Safety and Effectiveness of TEOSYAL® TPVM versus COMPARATOR for the remodeling of the lower face. | clinical trial | medical devices | multicentric | C2 | Dr Navid Alizadeh | TEOXANE SA |
Care Geneva Aesthetics, Geneva Clinique Cleage, Place du Molard 5 Private clinic, Avenue de Champel 24 Clinique des Grangettes, Route de Chêne 110 Clinique de la Croix d’Or, Rue de la Croix-d’Or 7 CHU More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.01.2023 | ||||
| 2022-D0093 | Post-Market, Randomized, Controlled, Multicenter, Prospective Trial Investigating Efficacy and Safety of Paclitaxel-Coated Drug Coated Balloon (LEGFLOW DCB) Treatment versus Uncoated Balloon Angioplas More ... | clinical trial | medical devices | multicentric | A1 | Dr. med. Amine Chouiter | Cardionovum GmbH |
Hôpital de la Providence, Neuchâtel INSELSPITAL, Universitätsklinikum Bern, Bern Service de chirurgie vasculaire, Centre hospitalier universitaire vaudois (CHUV), Service de chirurgie vasculaire Cent More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern | 27.03.2023 | ||||
| 2022-D0092 |
Assessing the symptomatic benefit of slow-wave activity reduction using wearables and sensor-based characterization of depression: a randomized, counter-balanced crossover study |
clinical trial | medical devices | monocentric | C2 | Dr. Giulia Da Poian | ETHZ - Department of Health and Science Technology |
ETH Zurich, Zurich |
Kantonale Ethikkommission Zürich | 20.12.2022 | Study has ended | ||||
| 2022-D0091 | Radio-ablation of malignant primary liver lesions (hepato-cellular carcinoma, HCC), followed by surgical resection (ablate – resect) | clinical trial | medical devices | monocentric | C2 | MD Alessandra Cristaudi | BetaGlue Technologies SpA |
Ente Ospedaliero Cantonale (EOC) Ospedale Regionale di Lugano – Civico Dipartimento di Chirurgia, Lugano |
Comitato etico cantonale Ticino | 06.03.2023 | Study has ended | ||||
| 2022-D0090 | Beurteilung der Sichtbarkeit anatomischer Strukturen der Zähne, des Zahnhalteapparats, der angrenzenden anatomischen Regionen und der Lagebeziehungen in der Weisheitszahnregion durch optimierte Verwen More ... | clinical trial | medical devices | monocentric | A1 | Dr. Silvio Valdec | Universität Zürich |
Universität Zürich, Zürich |
Kantonale Ethikkommission Zürich | 22.11.2022 | |||||
| 2022-D0087 | Simplified meal approach study using hybrid closed-loop insulin delivery in youth and young adults with type 1 diabetes – a randomised controlled two-centre crossover trial | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. et Dr. phil. Lia Bally | Universitätsklinik für Diabetologie, Endokrinologie, klinische Ernährung und Metabolismus Inselspital Bern |
Universitätsklinik für Diabetologie, Endokrinologie, klinische Ernährung und Metabolismus, Bern Abteilung Endokrinologie und Diabetologie, Universitäts-Kinderspital Zürich, Abteilung Endokrinologie u More ... |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 25.11.2022 | yes | Study has ended | ||
| 2022-D0086 |
Prospective Multicenter Confirmatory Clinical Evaluation of Novilase® Interstitial Laser Therapy for the Focal Destruction of Malignant Breast Tumours ≤15 mm (BR-003) |
clinical trial | medical devices | multicentric | A2 | Dr Heike Frauchiger-Heuer | Novian Health Inc |
University Hospital Zurich, Zurich Breast Centre Zurich, Seefeldstrasse 214 |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 22.11.2022 | ||||
| 2022-D0085 | Physician Initiated Trial Investigating ESAR (EVAR plus Heli-FX EndoAnchors) and FEVAR for the treatment of aortic aneurysms with short infrarenal aortic neck. | clinical trial | medical devices | monocentric | A1 | Prof Dr med Drosos Kotelis | FCRE - Foundation for Cardiovascular Research and Education GmbH |
Inselspital, Universitätsspital Bern Universitätsklinik für Gefässchirurgie Herz Gefäss Zentrum, Bern |
Kantonale Ethikkommission Bern | 24.02.2023 | |||||
| 2022-D0084 | TicIn for the Treatment of coronAry lesioNs with Drug Eluting Balloons | clinical trial | medical devices | monocentric | A2 | Prof. Dr. Marco Valgimigli | Istituto Cardiocentro Ticino |
Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 21.10.2022 | |||||
| 2022-D0083 | IMPACT OF SILICON-BASED FORMULATIONS ON WOUND HEALING OF LASER-INDUCED MICROSCOPIC SKIN LESIONS | clinical trial | medical devices | monocentric | A2 | Dr. Hans-Joachim Laubach | Stratpharma AG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.03.2023 | Study has ended | ||||
| 2022-D0080 | Retrospective clinical evaluation of nano-hybrid-composite denture teeth SR Phonares II | clinical trial | medical devices | monocentric | A1 | Dr. med. dent. Ronny Watzke | Ivoclar Vivadent AG |
Ivoclar Vivadent AG, Schaan |
Kantonale Ethikkommission Zürich | 26.09.2022 | Study has ended | ||||
| 2022-D0079 | Comparison between the non-powered AEON™ Endostapler and Echelon FLEX™ Powered plus Stapler with regards to the closure of lung tissue after lung resection in the presence of severe lung emphysema: A More ... | clinical trial | medical devices | monocentric | A1 | Eric Francis Macharia-Nimietz | University Hospital of Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.10.2022 | Study has ended | ||||
| 2022-D0078 | Comparison of Flow-Controlled Ventilation with EVONE Tritube and High frequency Jet Ventilation in Patients undergoing Laryngotracheal Surgery | clinical trial | medical devices | monocentric | A1 | Dr. Gergely Albu | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 24.10.2022 | |||||
| 2022-D0077 | Stimulations cérébrales non-invasives innovantes dans la réhabilitation des patients atteints d’une lombalgique chronique. | clinical trial | medical devices | monocentric | A1 | Stéphane Armand | Hopitaux Universitaires de Genèves |
UNIGE HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.12.2022 | |||||
| 2022-D0074 | Validation of CPM#1 compressibility ratio in a clinical study of healthy volunteers: evaluation of the test-retest reliability | clinical trial | medical devices | monocentric | C2 | Dr med Beat Lehmann | Compremium AG |
Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 25.10.2022 | Study has ended | ||||
| 2022-D0073 | The diagnostic accuracy of sonography in indirect elbow trauma compared with plain x-ray: a prospective single centre comparative diagnostic accuracy study | clinical trial | medical devices | monocentric | A1 | Dr. Eckehart Schöll | Merian Iselin Klinik |
Merian Iselin Klinik, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.09.2022 | |||||
| 2022-D0072 | Evaluation of monolithic milled complete removable dentures | clinical trial | medical devices | monocentric | A1 | Dr Sabrina Maniewicz | Clinique universitaire de médecine dentaire |
Clinique universitaire de médecine dentaire, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 02.08.2022 | Study has ended | ||||
| 2022-D0071 | Tumor heterogeneity of renal tumors assessed by multiparametric MRI with direct radiological-histopathological correlation: an explorative study | clinical trial | medical devices | monocentric | A1 | PD Dr. Andreas Hötker | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 05.08.2022 | Study has ended | ||||
| 2022-D0070 |
CRT-DRIVE Cardiac Resynchronization Therapy DeliveRy guided non-Invasive electrical and VEnous anatomy assessment |
clinical trial | medical devices | monocentric | C2 | Prof. Angelo Auricchio | XSpline S.p.A. |
Cardiocentro Ticino, Lugano |
Comitato etico cantonale Ticino | 06.02.2023 | |||||