| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-02048 |
Exploring the Association of Mucispirillum spp. with Inflammatory Bowel Disease in Humans (AMWIH): A Prospective Multi-Centre Observational Trial |
non clinical, involving persons | monocentric | A | Prof. Dr. med. Stephan Brand | Kanstonsspital St. Gallen |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 28.10.2021 | ||||||
| 2021-02047 | Virtual Reality (VR) to assess gesture execution in schizophrenia | non clinical, involving persons | monocentric | A | PhD/Anastasia Pavlidou | University Hospital of Psychiatry, University of Bern |
Translational Research Centre, University Hospital of Psychiatry, University of Bern, Bern |
Kantonale Ethikkommission Bern | 24.01.2022 | ||||||
| 2021-02045 | Clinical outcomes in children, adolescents and young adults with sarcomas of the head and neck treated with pencil beam scanning proton therapy | personal data/biological material | monocentric | Prof. Damien C. Weber | Zentrum für Protonentherapie ZPT |
Zentrum für Protonentherapie, Villigen PSI |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.11.2021 | Study has ended | ||||||
| 2021-02044 | Varietätenerwerb im Alemannischen Sprachraum (D-A-CH). Empirische Erkenntnisse zur Sprachentwicklung im Kleinkind-, Vorschul- und Schulalter aus der Perspektive der Logopädie, Variations- und Neuroli More ... | non clinical, involving persons | monocentric | A | Dr. Mirja Bohnert-Kraus | Schweizer Hochschule für Logopädie Rorschach |
Schweizer Hochschule für Logopädie Rorschach (SHLR), Rorschach |
Ethikkommission Ostschweiz (EKOS) | 18.11.2021 | yes | |||||
| 2021-02043 | Assessment of the female androgen status through free androgen index | personal data/biological material | monocentric | Prof. Dr. med. Petra Stute | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 16.08.2022 | |||||||
| 2021-02042 | Impact of the COVID-19 Epidemic on Paediatric Spinal Care | personal data/biological material | monocentric | Prof. Dr. med. Carol Hasler | Hospital for Special Surgery |
Children's Hospital, University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.10.2021 | |||||||
| 2021-02041 | Analysis of the implementation of Active Surveillance for Low Risk Prostate Cancer in Zurich a decade after the Guideline Change | personal data/biological material | monocentric | PD Dr. med Cedric Poyet | Klinik für Urologie |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 26.11.2021 | |||||||
| 2021-02040 | Removal of primary motor cortex of face area during surgery of lower grade gliomas and neurological outcome- what to expect? | personal data/biological material | monocentric | Dr. med. Katharina Lutz | Department of Neurosurgery, Inselspital |
Department of Neurosurgery, Inselspital, Bern |
Kantonale Ethikkommission Bern | 08.11.2021 | Study has ended | ||||||
| 2021-02038 | The acute cardiorespiratory response to blood-flow restricted versus traditional exercise training regimens (CaRe BFR): 4 randomized crossover studies | clinical trial | other clinical trials | monocentric | A | PD Dr. med / Christian / Clarenbach | Klinik für Pneumologie |
Klinik für Pneumologie Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 26.11.2021 | |||||
| 2021-02036 | An open label feasibility study of fecal microbiota transplantation in patients with malignancies not responding to cancer immunotherapy | clinical trial | other clinical trials | monocentric | B | Prof. Dr. Michael Scharl | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 14.01.2022 | Study has ended | ||||
| 2021-02034 | Role of pre operative brain Imaging in patients with NSCLC Stage I | personal data/biological material | multicentric | MD, PhD Fabrizio Minervini | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern Chuv, Lausanne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.10.2021 | ||||||
| 2021-02033 | Bacterial spectrum and antibiotic management in uncomplicated and complicated appendicitis at the Children’s Hospital Lucerne, LUKS | personal data/biological material | monocentric | KD Dr.med. Michael Büttcher | Kinderspital, LUKS |
Kinderspital, LUKS, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.12.2021 | |||||||
| 2021-02032 | Defining the urinary iodine concentration threshold indicating iodine deficiency in pregnant women by using thyroglobulin | personal data/biological material | monocentric | Dr. Sc. Maria Andersson | ETH Zurich |
University Children's Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 07.12.2021 | |||||||
| 2021-02031 | Long-term Outcomes of Childhood Adversities on DNA-Methylation | personal data/biological material | monocentric | Dr. Marc Schmid |
Universitäre Psychiatrische Kliniken (UPK), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.10.2021 | ||||||||
| 2021-02029 | MK-1084-001: A Phase 1, Open-Label, Multicenter Study to Assess Safety, Tolerability, PK, and Efficacy of MK-1084 as Monotherapy and in Combination With Pembrolizumab in Subjects with KRASG12C Mutant More ... | clinical trial | drugs | phase 1 | multicentric | C | Prof. Dr. Dr. med. Markus Jörger | Merck Sharp & Dohme LLC |
Kantonsspital St. Gallen, St. Gallen Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona |
Ethikkommission Ostschweiz (EKOS) | Comitato etico cantonale Ticino | 23.12.2021 | |||
| 2021-02028 | MR1-restricted T cell response to primary AML cells | personal data/biological material | monocentric | Dr. Lucia Mori | Matterhorn Biosciences AG |
Matterhorn Biosciences AG, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.10.2021 | |||||||
| 2021-02027 | Weight Loss and Treatment Patterns in a Real-World Population of Adults Receiving Saxenda® for Weight Management in Routine Clinical Practice in Switzerland | personal data/biological material | multicentric | Dr. Philipp Gerber | Novo Nordisk Pharma AG |
UniversitätsSpital Zürich, Zürich Praxis Dr med Stefan Schäfer, Bern Inselspital Bern, Bern Universitätsspital Basel, Basel Kantonsspital Olten, Olten LUKS Spitalbetriebe AG, Luzern Hopitaux Universit More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche G More ... | 26.11.2021 | Study has ended | |||||
| 2021-02026 | QUEST STUDY : QUantitative EEG for the monitoring of Sedation depth in mechanically venTilated critically ill patients. | personal data/biological material | monocentric | Prof. Mauro Oddo | CHUV-SMIA-DG |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 25.10.2021 | Study has ended | ||||||
| 2021-02025 | Recombinant human C1 esterase inhibitor (conestat alfa) in the prevention of acute ischemic cerebral and renal events after transcatheter aortic valve implantation: a multi-center, randomized, double- More ... | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. med. Michael Osthoff | Innere Medizin |
University Hospital Basel, Basel Stadtspital Triemli, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 30.11.2021 | |||
| 2021-02024 | A Phase 3, Randomized, Double-blind, Controlled Study Evaluating the Efficacy and Safety of VX-121 Combination Therapy in Subjects With Cystic Fibrosis Who Are Homozygous for F508del, Heterozygous for More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. Alexander Möller | Vertex Pharmaceuticals (Germany) GmbH |
Universitäts-Kinderspital Zürich – Eleonorenstiftung, Zürich Quartier Bleu, Praxis für Pneumologie, Am Lindenhofspital, Bern Réseau Hospitalier Neuchâtel Départment de médicine, Neuchâtel |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.06.2022 | yes | Study has ended | |