BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
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2024-00980 | Observation of balance and gait in neurological disease | non clinical, involving persons | multicentric | A | Sarah Hösli | University Hospital Zurich |
Department of Neurology, University Hospital Zurich, Zurich Klinik Lengg, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 22.10.2024 | |||||
2024-00979 | Technical advances DBS | personal data/biological material | monocentric | Prof. Dr. Lennart Stieglitz | University Hospital Zurich, Campus |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 16.07.2024 | |||||||
2024-00975 | Robotic right hemicolectomy with intracorporeal anastomosis versus laparoscopic right hemicolectomy with extracorporeal anastomosis for colorectal cancer (PRORHEM): a randomized controlled trial. | clinical trial | other clinical trials | monocentric | A | Dr Jeremy Meyer | Hôpitaux Universitaires de Genève |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.01.2025 | |||||
2024-00973 | Identification of subphenotypes in critically ill patients requiring extracorporeal membrane oxygenation (ECMO) support | personal data/biological material | monocentric | Prof. Dr. Sascha David | University Hospital Zurich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 16.08.2024 | |||||||
2024-00972 | Patient reported outcomes from routine clinical care in Medical Oncology at the University Hospital Basel - comprehensive analyses on feasibility, adherence and outcomes | personal data/biological material | monocentric | Dr Benjamin Kasenda | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.05.2024 | |||||||
2024-00971 | Multi-center, double-blind, randomized, placebo-controlled, parallel-group, polysomnography, dose-finding study assessing the efficacy, safety, and pharmacokinetics of multiple-dose oral administratio More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Alexandre N. Datta | Idorsia Pharmaceuticals Ltd |
Universitäts-Kinderspital beider Basel (UKBB), Basel Neurocentro EOC, Lugano |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Comitato etico cantonale Ticino | 02.10.2024 | yes | ||
2024-00970 | TRI0372 - CLNP023X2203: Additional Research approval | personal data/biological material | monocentric | Anna Schubart, PhD | Novartis Pharma AG - Biomedical Research |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.05.2024 | |||||||
2024-00969 | Evaluation and comparison between general anesthesia VS two types of combined anesthesia (general and spinal anesthesia) for opioid consumption in laparoscopic hysterectomy: a Multi-Center, Randomized More ... | clinical trial | other clinical trials | monocentric | A | Dr. Med. Roberto Dossi | EOC |
EOC, Bellinzona |
Comitato etico cantonale Ticino | 13.11.2024 | |||||
2024-00967 | MK-7240-008: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Program to Evaluate the Efficacy and Safety of Tulisokibart in Participants with Moderately to Severely Active Crohn’s Disease | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med. Luc Biedermann | Merck Sharp & Dohme LLC |
Universitätsspital Zürich, Zürich Intesto, Gastroentrologische Praxis Crohn-Colitis-Zentrum, Bern Clarunis – Universitäres Bauchzentrum Basel, Basel HOCH Health Ostschweiz, Kantonsspital St. Gallen, S More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 09.08.2024 | |||
2024-00966 | Follow-up of unruptured intracranial aneurysms with Ultra-High Field 7 Tesla MRI | non clinical, involving persons | monocentric | A | PD Dr. med. Johannes Goldberg | Department of Neurosurgery |
Department of Neurosurgery, Bern |
Kantonale Ethikkommission Bern | 17.12.2024 | ||||||
2024-00965 |
SAKK 66/22 Intratumoral INT230-6 followed by neoadjuvant Pembrolizumab and chemotherapy in patients with early triple-negative breast cancer (TNBC). An open-label randomized two-cohort phase 2 clini More ... |
clinical trial | drugs | phase 2 | multicentric | C | Prof. D r. med. Markus Joerger | SAKK |
Kantonsspital St.Gallen, St.Gallen Tumor Zentrum Aarau, Aarau Kantonsspital Baselland, Liestal St. Claraspital AG, Basel Tumor- und BrustZentrum Ostschweiz, St.Gallen Istituto Oncologico della Svizzer More ... |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 12.09.2024 | |||
2024-00963 | 20220028_A Phase 1 First-in-Human Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of AMG 355 as Monotherapy and in Combination with Pembrolizumab in Subjects with Advanced Sol More ... | clinical trial | drugs | phase 1 | multicentric | C | Anastasios Stathis | Amgen Inc |
Istituto Oncologico della Svizzera Italiana, Bellinzona Jörger, St. Galen |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS) | 30.08.2024 | |||
2024-00962 | Pulmonary artery pulsatility index in aortic stenosis: detailed non-invasive and invasive characterization and prognostic impact after valve replacement (AS-PAPi) | personal data/biological material | monocentric | Prof. Dr. Micha Maeder | Kantonsspital St. Gallen |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 16.05.2024 | |||||||
2024-00961 | Practice of Fluid Therapy in Critically Ill Invasively Ventilated Patients (PRoFLUID)––an international multicenter observational cohort study | personal data/biological material | monocentric | Prof. Carmen Pfortmueller | Amsterdam University Medical Centers location ‘AMC’ |
Inselspital Bern, 3010 Bern |
Kantonale Ethikkommission Bern | 18.07.2024 | |||||||
2024-00960 | Influence of the menstrual cycle on the electrocardiogram and the autonomic nervous system in young women | non clinical, involving persons | monocentric | A | Prof. Dr. Christian Müller | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.06.2024 | yes | |||||
2024-00959 | The MUSICare Project: Effects of Differentiated Music Exposure on Exercise-Related Affect Among Cardiac Rehabilitation Inpatients | clinical trial | other clinical trials | monocentric | A | Medical Doctor Elena Tessitore | University Hospital of Geneva |
Cardiology and Internal Medicine and rehabilitation, Hospital “Beau-Séjour”, Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.11.2024 | |||||
2024-00957 | RECOVER: Investigation into the Consequences of Opioid Medication Use on Neurological Recovery and Functioning in Acute Management of Spinal Cord Injury | personal data/biological material | monocentric | PD Dr Marija Glisic | Swiss Paraplegic Research |
Swiss Paraplegic Research, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.06.2024 | |||||||
2024-00955 | Tackling domain shifts in pediatric neuroimaging: bridging advanced computational MR techniques and clinical practice | non clinical, involving persons | monocentric | A | Meritxell Bach Cuadra | CHUV - CIBM PET03/02/21046 |
CIBM, Radiology Department, CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.06.2024 | ||||||
2024-00954 | Überleben nach Magentumorresektion in Abhängigkeit der perioperativen Chemotherapie unter Berücksichtigung der Lebensqualität - Magenkarzinom Studie - Unterschied zwischen unterschiedlichen Chemothera More ... | personal data/biological material | monocentric | PD. Ignazio Tarantino, MD, MSc |
Department of General, Visceral, Endocrine, and Transplantation Surgery, Kantonsspital St. Gallen, Switzerland, St Gallen |
Ethikkommission Ostschweiz (EKOS) | 13.05.2024 | ||||||||
2024-00953 | SonoML: Classification of Ultrasound Examinations in Emergency Medicine Using Machine Learning | personal data/biological material | monocentric | Prof. Dr. med. Gert Krummrey | Inselspital, Universitätsklinik für Notfallmedizin |
Inselspital, Universitätsklinik für Notfallmedizin, Bern |
Kantonale Ethikkommission Bern | 27.06.2024 | |||||||