| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01226 | Überleben bei Anastomoseninsuffizienz nach Rektumresektion, eine Frage des Managements? Rektum Insuffizienz Studie | personal data/biological material | monocentric | PD Dr. med. Ignazio Tarantino |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 11.07.2023 | ||||||||
| 2023-01225 | Quantification du sepsis par un algorithme au sein du Service des urgences du CHUV | personal data/biological material | monocentric | PD Dr. Sylvain Meylan | CHUV - Médecine intensive |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.09.2023 | |||||||
| 2023-01224 | Three-dimensional corrective osteotomies of Madelung deformities using patient-specific guides | non clinical, involving persons | monocentric | A | Prof. Dr. med. A. Schweizer | Univeristätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 07.11.2023 | yes | |||||
| 2023-01223 | Roll Over StudY for Patients Who Have Completed a Previous Oncology Study with Durvalumab and Are Judged by the Investigator to Clinically Benefit From Continued Treatment | clinical trial | drugs | phase 3 | monocentric | C | Dr Hasna BOUCHAAB | Astra Zeneca AB |
Centre hospitalier Universitaire Vaudois (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.03.2024 | ||||
| 2023-01222 | A Phase 1-3 Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ION363 in Amyotrophic Lateral Sclerosis Patients with Fused in Sarcoma Mutations More ... | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. Christoph Neuwirth | Ionis Pharmaceuticals, Inc. |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 05.10.2023 | yes | |||
| 2023-01221 | Virtual monoenergetic imaging to reduce metal artifacts in tin-prefiltered photon counting CT of the ankle | personal data/biological material | monocentric | Prof. Dr. Reto Sutter | University Hospital Balgrist |
University Hospital Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 15.08.2023 | |||||||
| 2023-01220 | Physiological factors affecting myocardial blood flow as assessed by quantitative positron emission tomography myocardial perfusion imaging | personal data/biological material | monocentric | Prof. Dr. med. Ronny Ralf Büchel | University Hospital Zurich |
University Hospital Zuricu, Zürich |
Kantonale Ethikkommission Zürich | 22.08.2023 | |||||||
| 2023-01219 | Monitoring of Torque Teno Virus Levels in Lung Transplantation as a Marker for Immunosuppression | non clinical, involving persons | monocentric | A | Prof. Dr. med. Nicolas Müller | University Hospital Zurich |
University Hospital of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 15.09.2023 | ||||||
| 2023-01218 | Monotherapy with a P2Y12 inhibitor followed by a direct-acting oral anticoagulant in patients with ATRial fIbrillation undergoing suprafleX coronary stent implantation (MATRIX-2) | clinical trial | other clinical trials | multicentric | B | Prof. Stephan Windecker | Insel Gruppe AG Bern University Hospital |
Inselspital, Bern University Hospital, Bern Universitätsspital Basel, Klinik für Kardiologie, Basel Hôpitaux Universitaires de Genève,, Genève Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino | 29.09.2023 | ||||
| 2023-01217 | Fully digital occlusion planning in orthognathic surgery | personal data/biological material | multicentric | Prof. Dr. med. Dr. med. dent. Philipp Metzler | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.07.2023 | ||||||
| 2023-01216 | Infrared thermography to monitor breast cancer patients during neoadjuvant chemotherapy: An exploratory analysis | non clinical, involving persons | monocentric | A | Dr. med. Lorenzo Rossi | Istituto Oncologico della Svizzera Italiana |
Istituto Oncologico della Svizzera Italiana, Bellinzona |
Comitato etico cantonale Ticino | 23.08.2023 | ||||||
| 2023-01215 | Prädiktive Faktoren für den Aufenthaltsort von Patient:innen nach einer Neurorehabilitation – Eine prospektive Machbarkeitsstudie | non clinical, involving persons | monocentric | A | PhD Clare Maguire | REHAB Basel |
REHAB Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.09.2023 | ||||||
| 2023-01214 | Changes in body composition, self-reported symptoms and costs in one menstrual cycle: An explorative evaluation and cost analysis | non clinical, involving persons | monocentric | A | Prof. Dr. Heiner Baur | Berner Fachhochschule |
Berner Fachhochschule, Bern |
Kantonale Ethikkommission Bern | 24.08.2023 | ||||||
| 2023-01213 | Semaglutide-to-Tirzepatid-Switch (STS-3)-Studie: Prospektive Beobachtungsstudie eines zusätzlichen Effekts auf die glykämische Kontrolle und das Körpergewicht bei Patienten mit Diabetes, die von einer More ... | personal data/biological material | multicentric | Prof. Dr. Gottfried Rudofsky | Praxis Prof. Rudofsky |
Praxis Prof. Rudofsky, Olten Stoffwechselzentrum St. Gallen, St. Gallen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS) | 23.08.2023 | ||||||
| 2023-01212 | The causal effect of surgical and orthotics treatments to improve walking in persons with a neurological disorder, including cerebral palsy and those toe walking. | personal data/biological material | multicentric | Dr. Morgan Sangeux | UKBB |
UKBB, Basel HUG, Genève |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission Cantonale d'éthique de la recherche Genève (CCER) | 24.08.2023 | ||||||
| 2023-01211 | A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. Andrea Raballo | MGGM LLC |
Organizzazione sociopsichiatrica cantonale, Mendrisio |
Comitato etico cantonale Ticino | 21.02.2024 | ||||
| 2023-01210 | Management of benign and pre-invasive breast lesions: Comparison of rates of histologic underestimation in minimally invasive breast biopsies between 2000-2007 and 2008-2022 and investigation of patie More ... | personal data/biological material | monocentric | Dr. med. Cristian Bronz | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 30.08.2023 | |||||||
| 2023-01209 | A real-world retrospective analysis of non-small cell lung cancer (NSCLC) patients in a single centre: clinical outcome and prognostic value of molecular alterations | personal data/biological material | monocentric | Dr. med. Patrizia Froesch | Istituto Oncologico della Svizzera Italiana (IOSI) |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona |
Comitato etico cantonale Ticino | 13.07.2023 | |||||||
| 2023-01208 | SUNSHINE_BIO: Understanding the molecular basis of differential responses to prostate cancer treatments in a comprehensive retrospective cohort. | personal data/biological material | monocentric | Dr. med. Ricardo Pereira Mestre | Istituto oncologico della Svizzera Italiana (IOSI) |
Instituto Oncologico della Svizzera Italiana (IOSI), Bellinzona |
Comitato etico cantonale Ticino | 06.09.2023 | |||||||
| 2023-01207 |
A Phase 1, First-in-Human, Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects with Advanced Solid Tumors Étude de phase 1, de première adm More ... |
clinical trial | drugs | phase 1 | multicentric | C | Dr Krisztian Homicsko | Tolremo Therapeutics AG |
Département d'Oncologie, Service d’Immuno-Oncologie, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne Ospedale Regionale di Bellinzona e Valli, Bellinzona |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Comitato etico cantonale Ticino | 27.11.2023 | |||