| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-01449 | Swisskera - Multicenter cohort study for the use of cultured epithelial autografts (CEA) or cultured dermal-epidermal autografts (CDEA) in severely burned patients | non clinical, involving persons | multicentric | A | PD Dr. med. Sophie Böttcher | Universitys Children's Hospital Zurich |
University Children's Hospital Zurich, Zurich CHUV, Lausanne University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 29.04.2026 | yes | ||||
| 2025-01448 | Impact of electric assistance on the severity of cranio-facial and general traumas in bicycle accidents: A comparative analysis of e-bike and conventional bike accidents. | personal data/biological material | monocentric | Prof.Dr.Dr. Thomas Gander | Mund-,Kiefer-&Gesichtschirurgie Luzern Kantonsspital |
Luzern Kanton Spital Mund-Kiefer & Gesichtschirurgie, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.08.2025 | |||||||
| 2025-01447 | A Randomized, Placebo-controlled, Double-blind, Multicenter Phase 3 Protocol to Assess the Efficacy and Safety of Nipocalimab in Adults with Moderate to Severe Sjögren's Disease (SjD) | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. Florian Kollert | Janssen-Cilag International NV |
Universitatsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.12.2025 | ||||
| 2025-01446 | Gastrointestinal Oxygenation and the Gut Microbiome: Implications for Weight Management after Roux-en-Y Gastric Bypass | personal data/biological material | monocentric | Dr. sc. med. Michele Serra | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 16.09.2025 | |||||||
| 2025-01445 | CT angiography of the cerebral arteries in whole-body CT of trauma patients – Image quality and diagnostic certainty compared to a dedicated neuroradiologic scan protocol | personal data/biological material | monocentric | Prof. Dr. André Euler | Kantonsspital Baden |
Institut für Radiologie, Kantonsspital Baden, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.07.2025 | |||||||
| 2025-01443 | A Phase 3 open-label, randomized, controlled study to evaluate the efficacy and safety of petosemtamab compared with Investigator’s choice monotherapy treatment in previously treated patients with inc More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Markus Jörger | Merus B.V. |
HOCH Health Ostschweiz, Kantonsspital St.Gallen, St. Gallen Hôpitaux Universitaires de Genève (HUG), Genève EOC - Istituto Oncologico della Svizzera Italiana, Bellinzona Centre hospitalier universitai More ... |
Ethikkommission Ostschweiz (EKOS) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino | 13.11.2025 | |||
| 2025-01442 | Hip Surgery in Geriatric Patients using Supra-Inguinal Fascia Iliaca Block with Sedation: A Case Series | personal data/biological material | monocentric | Aubry Schaefer | HUG |
Hopitaux Universitaire de Geneve, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 28.04.2026 | |||||||
| 2025-01441 | Clinical application of a combined Lactulose H2-breath test with abdominal imaging to assess the digestive function. | personal data/biological material | monocentric | Prof. Dr. med. Mark Fox | Klinik Arlesheim |
Klinik Arlesheim, Arlesheim |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.07.2025 | |||||||
| 2025-01440 | Étude rétrospective de la prise en charge des patients avec dysplasie fibreuse | personal data/biological material | monocentric | MER Dr Aline Bregou | CHUV |
CHUV, Lausanne, Suisse |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.09.2025 | |||||||
| 2025-01439 | Sodium-Bicarbonate Administration in Critically Ill Patients: Carbon-Dioxide Load and Impact on Mechanical Ventilation (BiCO2) | personal data/biological material | monocentric | Prof. Dr. med. Sascha David | University Hospital Zurich |
Institute of Intensive Care Medicine, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 09.09.2025 | |||||||
| 2025-01438 | Outcomes of urethral strictures in patients treated with Optilume | personal data/biological material | multicentric | Dr. med. Luca Afferi | Urologische Klinik, Kantonsspital Aarau, Tellstrasse 25 |
Kantonsspital Aarau, Aarau Kantonsspital Baselland, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.09.2025 | ||||||
| 2025-01437 | Einfluss einer infrarotabsorbierenden Brillenglasbeschichtung auf die Augenoberflächentemperatur, den Tränenfilm und die korneale Sensitivität: eine explorative Pilotstudie | non clinical, involving persons | monocentric | A | Dr. Martin Lörtscher | Fachhochschule Nordwestschweiz FHNW |
Institut für Optometrie, Fachhochschule Nordwestschweiz, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.10.2025 | ||||||
| 2025-01436 | Infections, climate change and arthropods - understanding the threat to Switzerland | personal data/biological material | monocentric | Prof. Dr. Patricia Schlagenhauf | University of Zürich, Epidemiology, Biostatistics and Prevention Institute |
Epidemiology, Biostatistics and Prevention Institute (EBPI), University of Zürich, Zürich |
Kantonale Ethikkommission Zürich | 10.04.2026 | |||||||
| 2025-01435 | Vergleich der Kniemechanik vor und nach eines totalen Kniegelenkersatzes mit mechanischer versus personalisierter Ausrichtungstechnik | deceased persons | monocentric | Dipl.-Ing. Iris Blatter | Zimmer Switzerland Manufacturing GmbH |
Zimmer Switzerland Manufacturing GmbH, 8404 Winterthur |
Kantonale Ethikkommission Zürich | 23.09.2025 | |||||||
| 2025-01434 | TRI0392 - Investigating Skin Rash Mechanisms in Alpelisib-treated Patients | personal data/biological material | monocentric | Maria Vono, PhD | +41615292096 |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.07.2025 | |||||||
| 2025-01432 | Randomized, Double-Blind, Placebo-Controlled, Crossover Study Investigating the Role of Potassium Channels in Working Memory Impairments of Chronic Cocaine Users | clinical trial | other clinical trials | monocentric | B | Prof. Dr. Boris. B. Quednow | Universität Zürich |
Psychiatrische Universitätsklinik Zürich, Zürich |
Kantonale Ethikkommission Zürich | 10.02.2026 | |||||
| 2025-01430 | Étude d’implémentation d’une consultation d’oncologie intégrative au sein du Centre de médecine intégrative et complémentaire du CHUV (CEMIC_ONCO) | non clinical, involving persons | monocentric | A | MD PhD, Chantal Berna Renella | CHUV - Centre de médecine intégrative et complémentaire (CEMIC) |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.08.2025 | ||||||
| 2025-01429 | Biomechanical comparison of different trochanter stabilizing plate configurations by extramedullary osteosyntheses in pertrochanteric femur fractures with unstable lateral wall | deceased persons | monocentric | Ivan Zderic | AO Research Institute Davos |
AO Research Institute Davos, Davos |
Kantonale Ethikkommission Zürich | 17.10.2025 | |||||||
| 2025-01427 | Association of plasma neurofilament and GFAP concentrations with disease severity, magnetic resonance imaging results, and neurodevelopmental outcome in neonatal and paediatric intensive care patients | personal data/biological material | monocentric | MD, Philipp Baumann | University Children’s Hospital Zurich - Eleonore Foundation |
University Children’s Hospital Zurich - Eleonore Foundation, Zurich |
Kantonale Ethikkommission Zürich | 10.10.2025 | |||||||
| 2025-01426 | Carrying out a data collection of patients with ecstatic epilepsy and ecstatic symptoms | non clinical, involving persons | monocentric | A | Prof Fabienne Picard | HUG |
HUG, Geneve |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.12.2025 | ||||||