| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-01230 | Bioengineering native osteochondral architecture: From in vitro models to biological joint resurfacing | personal data/biological material | multicentric | Prof. Marcy Zenobi-Wong | ETH Zürich |
ETH Zürich / Tissue Engineering & Biofabrication, 8093 Zürich Sportclinic Zürich, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 24.10.2025 | ||||||
| 2025-01229 | Quantifiaction of incomplete A2-Pulley ruptures in rock climbers – an ultrasound analysis of 32 cases. | personal data/biological material | monocentric | Prof.Dr.med.Andreas Schweizer | Balgrist University Hospital |
Balgrist University Hospital, Zurich |
Kantonale Ethikkommission Zürich | 09.09.2025 | |||||||
| 2025-01228 | Pragmatic geriatric assessment (pGA) before bispecific antibody and CAR-T-Cell therapy (GA-ACT Trial) for the prediction of toxicity and outcomes in older patients scheduled for chimeric antigen recep More ... | non clinical, involving persons | multicentric | A | Dr. med. Wiebke Rösler | University Hospital Zurich |
University Hospital Zurich, Zurich Inselspital Bern, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 03.10.2025 | |||||
| 2025-01227 | Heart Team Approach in Treatment of Mitral Regurgitation: Patient Selection und Longterm Outcome. | personal data/biological material | monocentric | Prof. Dr. med. Patric Biaggi | HerzKlinik Hirslanden |
HerzKlinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 05.09.2025 | |||||||
| 2025-01226 | Charakterisierung des Mikrochimärismus nach allogener Stammzelltransplantation. | personal data/biological material | monocentric | Dr. med. Corinne Widmer | Universitätsspital Basel |
Klinik für Hämatologie, Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.10.2025 | |||||||
| 2025-01225 | Comparison of surgical and conservative treatment of condylar head fractures based on functional and anatomical outcome | personal data/biological material | monocentric | PD Dr. med. Dr. med. dent. Maximilian Wagner | USZ |
University Hospital Zurich (USZ), Zurich |
Kantonale Ethikkommission Zürich | 03.10.2025 | |||||||
| 2025-01224 |
Understanding participation in child healthcare: an ethnographic observation study in Switzerland |
non clinical, involving persons | monocentric | A | Prof. Dr. Frank Wieber | Zurich University of Applied Sciences (ZHAW) |
ZHAW, 8400 Winterthur |
Kantonale Ethikkommission Zürich | 17.10.2025 | yes | |||||
| 2025-01223 | Impact of Neuropsychological Dysfunction on the Neurosurgical and Anesthetic Consent Process | personal data/biological material | monocentric | Dr John G Gaudet | Bureau du Promoteur de Recherche du CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.12.2025 | |||||||
| 2025-01222 | MicroElectrodes and MicroBipolar mapping to improve Ventricular Arrhythmias Ablation | personal data/biological material | monocentric | Dr. Med. Marco Bergonti | Istituto Cardiocentro Ticino - Ente Ospedaliero Cantonale |
Istituto Cardiocentro Ticino - Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 26.08.2025 | |||||||
| 2025-01220 | Do Thyroid Carcinomas with BRAF V600E Mutations Behave Differently in Different Patient Populations: a Retrospective Multicenter International Study | personal data/biological material | monocentric | PD Dr. med. Gregoire Morand | Otorhinolaryngology |
University Hospital Zurich, Department of Otorhinolaryngology, Head & Neck Surgery, Zurich |
Kantonale Ethikkommission Zürich | 18.12.2025 | |||||||
| 2025-01219 | Epigenetic triggers leading to cardiac wild-type transthyretin amyloidosis (wtATTR) cardiomyopathy | personal data/biological material | monocentric | Prof. Dr. med. Ronny R. Büchel | University Hospital Zürich |
University Hospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 22.08.2025 | |||||||
| 2025-01218 | Évaluation prospective de l’implémentation de l’évaluation échoguidée du positionnement des cathéters centraux, en néonatalogie après une formation condensée et ciblée. | non clinical, involving persons | monocentric | A | Dr Sébastien Joye | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.08.2025 | yes | |||||
| 2025-01217 | A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate Efficacy and Safety of Mezagitamab (TAK-079) in Study Participants with Primary IgA Nephropathy in Combination wit More ... | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. Britta George, MBA | Takeda Development Center Americas, Inc. |
Nephrology University Hospital Zurich Rämistrasse 100 8091 Zurich, Switzerland, Zurich |
Kantonale Ethikkommission Zürich | 22.08.2025 | ||||
| 2025-01216 | 20240361 - A Phase 1b Open-label, Multicenter Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of Xaluritamig in Combination with Androgen Receptor Pathway I More ... | clinical trial | drugs | phase 1 | multicentric | C | Prof. Dr. med. Richard Cathomas | Amgen Inc. |
Kantonsspital Graubünden, Department Innere Medizin, Chur HOCH Health Ostschweiz Kantonsspital St. Gallen, St. Gallen Centre Hospitalier Universitaire Vaudois, Lausanne |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 29.08.2025 | |||
| 2025-01215 | Verwendung von Zellen aus menschlichem Knorpel für die Herstellung eines Knopelersatzes | personal data/biological material | multicentric | PD Dr. sc.nat Thomas Biedermann | Universität Zürich |
Universität Zürich, Zürich Inselspital Bern, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 26.09.2025 | ||||||
| 2025-01212 | Acute analgesic effects of 3,4-methylenedioxymethamphetamine (MDMA) on experimentally induced acute nociceptive pain, hyperalgesia and allodynia in healthy participants | clinical trial | other clinical trials | monocentric | B | Dr. med. Severin Vogt | Universitätsspital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.07.2025 | |||||
| 2025-01210 | Objective self-assessment of genital sensitivity | non clinical, involving persons | monocentric | A | Pre Jasmine Abdulcadir | University Hospital of Geneva |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 15.12.2025 | ||||||
| 2025-01207 | Brain abscesses in transplant recipients: a multicentre retrospective study | personal data/biological material | monocentric | Oriol Manuel | APHP |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 01.12.2025 | |||||||
| 2025-01206 | Nutzen und Kosteneffektivität in der Behandlung und Nachsorge von Hirnaneurysmen | personal data/biological material | monocentric | Prof. Dr. med. Serge Marbacher | Kantonsspital Aarau AG |
Kantonsspital Aarau AG, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.08.2025 | Study has ended | ||||||
| 2025-01205 | Can pancreatic resections be performed safely by a surgical fellow as a teaching procedure? Outcome of 160 patients between 2017-2023. | personal data/biological material | monocentric | PD Dr. med. Jörn-Markus Gass | Luzerner Kantonsspital |
Klinik für Allgemein- und Viszeralchirurgie, Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.08.2025 | |||||||