| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2017-02052 |
OPINION - A Phase IIIb, Single-arm, Open-label Multicentre Study of Olaparib Maintenance Monotherapy in Platinum Sensitive Relapsed non- Germline BRCA Mutated Ovarian Cancer Patients who are in Comp More ... |
clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Konstantin Dedes | AstraZeneca AB |
Universitätsspital Zürich, Zürich University Hospital Basel, Gynecological Cancer Centre, Basel Hôpitaux Universitaires de Genève - HUG, Geneve Kantonspital Frauenfeld, Frauenklinik, Frauenfeld Oncolo More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino | 16.03.2018 | Study has ended | ||
| 2017-02051 | Evaluation and optimization of hearing devices in 3-D complex audio environments | clinical trial | medical devices | monocentric | A1 | Prof Dr Norbert Dillier | Sonova AG |
University Hospital, Zürich |
Kantonale Ethikkommission Zürich | 20.02.2018 | Study has ended | ||||
| 2017-02050 | Validation of risk factors leading to shunt dependency in patients with malresorptive hydrocephalus after aneurysmal SAH (aSAH) in Switzerland: A retrospective data analysis of the Swiss SOS registry | personal data/biological material | monocentric | PD Dr. med. Serge Marbacher | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.12.2017 | Study has ended | ||||||
| 2017-02048 | Reasons for failure of primary total knee arthroplasty in Switzerland | personal data/biological material | monocentric | Prof. Dr. med. Michael Hirschmann | Kantonsspital Baselland, Bruderholz |
Kantonsspital Baselland, Bruderholz, Bruderholz |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.01.2018 | |||||||
| 2017-02047 | STandard versus Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI): A Multi-Centre, Randomized, Controlled Trial | clinical trial | other clinical trials | multicentric | B | Dr Antoine Schneider | Centre Hospitalier Universitaire Vaudois (CHUV) |
CHUV, Lausanne HUG, Geneva |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.04.2018 | Study has ended | |||
| 2017-02046 | Parameters of auto-immunity in cancer: clinical implications of the nucleolar staining of antinuclear antibodies | personal data/biological material | monocentric | MD/David Spoerl | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 31.01.2018 | |||||||
| 2017-02045 | Sarcopenia Prevention with a Targeted Exercise and Protein Supplementation Program | clinical trial | other clinical trials | multicentric | A | Prof. Dr. med. Heike A. Bischoff-Ferrari | UniversitätsSpital Zürich |
UniversityHospital Zurich, Zurich University Departement of Geriatric Medicine FELIX PLATTER, Basel |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.01.2018 | ||||
| 2017-02044 | Thermogenesis in Hyperthyroidism and Effect of Anti-Adrenergic Therapy | clinical trial | drugs | phase 4 | monocentric | A | PD Dr. Matthias Betz | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.12.2017 | Study has ended | |||
| 2017-02043 | Efficacy of Motivating Short Interventions for Smokers in Primary Care. A Cluster-RCT | clinical trial | other clinical trials | monocentric | A | Dr. med. Stefan Neuner-Jehle MPH | Institut für Hausarztmedizin |
Institut für Hausarztmedizin UZH/USZ, Zürich |
Kantonale Ethikkommission Zürich | 24.01.2018 | Study has ended | ||||
| 2017-02042 | Impact de l’introduction des panels gastro-intestinaux par PCR multiplex sur le traitement des infections digestives | personal data/biological material | monocentric | PD & MER / Serge / de Vallière | Policlinique Médicale Universitaire, CHUV |
Policlinique Médicale Universitaire,CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.02.2018 | Study has ended | ||||||
| 2017-02041 | Outcome of patients with minimal symptoms, large vessel occlusion (LVO): an analysis of the Swiss Stroke Registry. | personal data/biological material | monocentric | PD Dr.med Carlo W. Cereda |
Neurocentro Svizzera Italiana, Lugano |
Comitato etico cantonale Ticino | 05.06.2018 | ||||||||
| 2017-02040 | Immune Reconstitution in Relation to Conditioning Therapy in Pediatric Recipients of Hematopoietic Stem Cells | personal data/biological material | monocentric | MD PhD Mathias Hauri-Hohl |
University Children’s Hospital Zurich, 8032 Zurich |
Kantonale Ethikkommission Zürich | 21.12.2017 | ||||||||
| 2017-02039 | Repetitive transcranial magnetic stimulation (rTMS) to improve gesture control in schizophrenia – a randomised, placebo-controlled, double-blind crossover trial | clinical trial | medical devices | monocentric | A | Prof. Dr. med. Sebastian Walther | Universitätsklinik für Psychiatrie und Psychotherapie |
Universitätsklinik für Psychiatrie und Psychotherapie, Bern |
Kantonale Ethikkommission Bern | 21.12.2017 | Study has ended | ||||
| 2017-02038 | Exhaled Breath Analysis in pediatric patients exposed to environmental Tobacco Smoke | non clinical, involving persons | monocentric | A | Dr med et phil Jakob Usemann | UKBB |
UKBB, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.01.2018 | yes | Study has ended | ||||
| 2017-02037 | With-in subject comparison of brain activity in patients with tinnitus | non clinical, involving persons | monocentric | A | PD Dr. Wilhelm Wimmer | Hearing Research Laboratory, Department of ORL, Head and Neck Surgery |
Department of ORL, Head and Neck Surgery, Bern |
Kantonale Ethikkommission Bern | 20.12.2017 | Study has ended | |||||
| 2017-02036 | Prognostic values for urinary tract infections in patients with urolithiasis | personal data/biological material | monocentric | PD Dr. med. Thomas Hermanns | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 12.02.2018 | |||||||
| 2017-02035 | Motion perception and motion sickness during rotation | non clinical, involving persons | monocentric | A | Prof. Dominik Straumann | University Hospital Zurich |
UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 07.06.2019 | ||||||
| 2017-02033 | Prognostic impact of the use of antibiotics in patients with advanced non small-cell lung cancer (NSCLC) receiving PD-(L)1 targeting monoclonal antibodies | personal data/biological material | multicentric | PD Dr. med. et rer nat. Markus Joerger | Kantonsspital St.Gallen |
Cantonal Hospital, St. Gallen University Hospital Zürich, Zürich |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Zürich | 15.01.2018 | Study has ended | |||||
| 2017-02031 | A Phase 2, Multicenter Study to Assess the Efficacy and Safety of Autologous Tumor Infiltrating Lymphocytes (LN-144) for Treatment of Patients with Metastatic Melanoma | clinical trial | transplant products | multicentric | C | Dr Angela Orcurto | Iovance Biotherapeutics, Inc. |
CHUV, Lausanne Inselspital, Universitätsspital Bern, Bern |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern | 04.04.2018 | Study has ended | |||
| 2017-02030 | Effects of overnight storage conditions on conventional and CAD/CAM milled complete removable dental prostheses: a double-blind, crossover, randomized clinical trial. | clinical trial | other clinical trials | monocentric | A | Professor Frauke Müller | University Clinics of Dental Medicine, University of Geneva |
University Clinics of Dental Medicine, University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 31.01.2018 | Study has ended | ||||