| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-02051 | Fecal microbiome signature of multi-strain probiotics supplementation in children and adolescents with inflammatory bowel disease - a pilot study | clinical trial | other clinical trials | monocentric | A | PD Dr. med. Christiane Sokollik |
Universitätsspital für Kinderheilkunde, Bern |
Kantonale Ethikkommission Bern | 12.02.2024 | yes | |||||
| 2023-02050 | An Open-Label Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of OMS906 in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) | clinical trial | drugs | phase 2 | monocentric | C | Dr Mathilde Gavillet | Omeros Corporation |
Lausanne University Hospital CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 19.02.2024 | ||||
| 2023-02048 | Effectiveness of a patient-oriented discharge summary for older inpatients discharged home. | clinical trial | other clinical trials | monocentric | A | Prof. Cédric Mabire | UNIL - FBM - IUFRS |
IUFRS, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.07.2024 | |||||
| 2023-02047 |
A multi-center, multi-country prospective observational study of patients initiating T-DXd in the first or second treatment line for HER2+, and HER2-low unresectable and/or metastatic breast cancer |
non clinical, involving persons | multicentric | A | Prof. Dr. med. Christian Kurzeder | AstraZeneca |
Universitätsspital Basel, Basel Inselspital, Bern Kantonsspital Baselland, Liestal Hôpital Riviera Chablais, Rennaz |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.01.2024 | Study has ended | ||||
| 2023-02046 | Outcomes of patients with Oligometastatic Non-Small Cell Lung Cancer (NSCLC) treated with first line Immuno-/ or Chemoimmunotherapy | personal data/biological material | monocentric | Prof. Martin Früh | KSSG; Medical Oncology St. Gallen |
KSSG, Medical Oncology, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 14.12.2023 | |||||||
| 2023-02045 | Human-derived TDP-43 intrabodies to restore TDP-43 function in ALS | deceased persons | monocentric | Dr Nikole Zuniga | Mabylon AG |
Mabylon, Schlieren |
Kantonale Ethikkommission Zürich | 12.01.2024 | |||||||
| 2023-02044 | Transition de la pédiatrie à la médecine adulte lors du suivi des patients atteints d'une maladie inflammatoire de l'intestin | non clinical, involving persons | monocentric | A | Pr Andreas Nydegger | CHUV - DFME - Pédiatrie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.02.2024 | ||||||
| 2023-02043 | Effect of modulating pendular mechanism and step-to-step transition using a biofeedback system on energetics and mechanics of walking in healthy individual | non clinical, involving persons | monocentric | A | MER - PhD /Davide/Maltesta | ISSUL - UNIL |
UNIL- ISSUL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.12.2023 | ||||||
| 2023-02042 | Generating CAR T cells with optimal fitness by boosting mitochondrial metabolism | personal data/biological material | monocentric | Pr Denis Migliorini | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.09.2024 | |||||||
| 2023-02041 | Analgesic efficacy of IPACK versus selective tibial nerve block in patients scheduled for total knee arthroplasty under spinal anaesthesia with an adductor canal block: a randomised controlled double- More ... | clinical trial | other clinical trials | monocentric | A | Prof Eric Albrecht | CHUV - Anesthésiologie |
Chuv, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.01.2024 | |||||
| 2023-02039 | Évaluation radiologique de la relation entre la pente radiale et la position du carpe | personal data/biological material | monocentric | Pr Jean-Yves BEAULIEU |
Hôpitaux Universitaires de Genève, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 11.04.2024 | ||||||||
| 2023-02038 | Etude rétrospective des patients implantés d’un neurostimulateur de l’hypoglosse pour apnée du sommeil au CHUV | personal data/biological material | monocentric | Dr Karma Lambercy | CHUV - ORL |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 22.02.2024 | |||||||
| 2023-02036 | Evaluation of up-to-date information needs and expectations of UC patients | non clinical, involving persons | monocentric | A | Valérie Pittet | Unisanté - DESS |
Unisanté, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.02.2024 | ||||||
| 2023-02035 | Assessing the role of prolonged close contact in the spread of respiratory viral infections in schools | non clinical, involving persons | monocentric | A | Prof. Lukas Fenner | Institute of Social and Preventive Medicine (ISPM) |
ISPM, Bern |
Kantonale Ethikkommission Bern | 18.12.2023 | yes | |||||
| 2023-02033 | FORM: Fetal Phenomics to unravel the correlation between phenotype and genotype in prenatal malformations | embryos/fetuses | monocentric | Prof.Dr.med. Isabel Filges | Medizinische Genetik, Institut für Medizinische Genetik und Pathologie, niversitätsspital Basel |
Medical Genetics, University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.12.2023 | |||||||
| 2023-02032 | Impacte de la Gastric Peroral Endoscopic Myotomy (GPOEM) sur la fréquence des selles chez les patients atteints de gastroparésie et de trouble du transit chronique. | personal data/biological material | monocentric | Dr. Sébastien Godat | CHUV - Gastro-entérologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.01.2024 | |||||||
| 2023-02030 | Exploring the suitability of ants as diagnostic tools for premature rupture of amniotic membranes | personal data/biological material | monocentric | Dr Hélène LEGARDEUR | CHUV - DFME |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.01.2024 | |||||||
| 2023-02028 | Validation of the European consensus for the biomarker-based diagnosis of neurocognitive disorders: an investigator-initiated sponsored study (EuroValiCo) | personal data/biological material | monocentric | Pr. Giovanni Frisoni | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 08.01.2024 | |||||||
| 2023-02026 | Retrospective analysis of weight gain upon adjuvant anti-hormonal treatment in patients diagnosed with Hormonal-receptor positive early breast cancer | personal data/biological material | monocentric | Dr Julian Wampfler | Universitätsklinik für Medizinische Onkologie, Inselspital |
Universitätsklinik für Medizinische Onkologie, Inselspital, Bern |
Kantonale Ethikkommission Bern | 16.01.2024 | |||||||
| 2023-02025 | Snapshot Study of Incidence, Treatment and Outcome of distal Radius Fractures with or without concomitant Ulnar Styloid Fractures — an international comparison between the Netherlands and Switzerland | personal data/biological material | monocentric | Prof. Dr PhD Frank Beeres | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.04.2024 | |||||||