| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-00234 | CTQJ230A12203 - A randomized double-blind, placebo-controlled, multi-center trial assessing the impact of lipoprotein(a) lowering with pelacarsen (TQJ230) on the progression of calcific aortic valve s More ... | clinical trial | drugs | phase 2 | multicentric | C | Dr. med. Jonathan Michel | Novartis Pharma Schweiz |
Universitätsspital Zürich, Zürich Universitätsspital Basel, Basel HUG, Geneve EOC, Lugano |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino | 19.04.2024 | |||
| 2024-00233 | A superiority randomized controlled study on the efficacy of radiofrequency for the treatment of women patients with overactive bladder syndrome | clinical trial | other clinical trials | monocentric | B | PD Dr. med. Andrea Braga | Dept. Obstetrics and Gynaecology, EOC - Beata Vergine Hospital |
Dept. Obstetrics and Gynaecology, EOC - Beata Vergine Hospital, Mendrisio |
Comitato etico cantonale Ticino | 26.08.2024 | |||||
| 2024-00231 | Ticin regIstry for caTheter-based treAtments iN patIents with acute pUlmonary eMbolism | non clinical, involving persons | monocentric | A | Prof Marco Valgimigli | Cardiocentro Ticino Institute, EOC |
Cardiocentro Ticino Institute, EOC, Lugano, Lugano |
Comitato etico cantonale Ticino | 14.05.2024 | ||||||
| 2024-00230 | MK-2870-019: A Phase 3 Randomized Open-Label Study of Adjuvant Pembrolizumab With or Without MK-2870 in Participants With Resectable Stage II to IIIB (N2) NSCLC not Achieving pCR After Receiving Neoad More ... | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med. Michael Mark | Merck Sharp & Dohme LLC |
Kantonsspital Graubünden, Chur Spital Thurgau AG, Thurgau HFR hôpital fribourgeois, Fribourg |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.04.2024 | |||
| 2024-00229 | Biomechanical Evaluation of Various Refixation Techniques Following Extended Trochanteric Osteotomy and Trochanteric Fractures in a Cadaver Model | deceased persons | monocentric | Prof. Dr. med. Patrick Zingg | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 12.04.2024 | |||||||
| 2024-00228 | TRINITY – Use of commercial human milk samples for in-vitro assays | personal data/biological material | monocentric | Lucile Yart | La Société |
La Société des Produits Nestlé, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.12.2024 | |||||||
| 2024-00225 | Initial experience with Simultaneous Pancreas- and Kidney Transplantations from Donors after Circulatory Death in Switzerland and review of the current literature | personal data/biological material | monocentric | Dr. med. Fabian Rössler | Department of Surgery and Transplantation, University Hospital of Zürich |
University Hospital of Zürich, Zürich |
Kantonale Ethikkommission Zürich | 26.03.2024 | |||||||
| 2024-00224 | One year results and comparison of two double mobility prostheses for trapeziometacarpal arthritis | personal data/biological material | monocentric | Sebastian Hediger | Kantonsspital Frauenfeld |
Kantonsspital Frauenfeld, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 08.02.2024 | |||||||
| 2024-00223 |
Efficacy of Transversus Thoracic Muscle Plane Block in Patients undergoing Cardiac Surgery A randomized controlled, double blind trial |
clinical trial | other clinical trials | monocentric | A | PD Dr Sina Grape | Hôpital du Valais |
Service d'Anesthésiologie, Centre Hospitalier du Valais Romand, Sion |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.04.2024 | |||||
| 2024-00222 | Malleostapedotomy: a 20-year updated review of surgical results | personal data/biological material | monocentric | Prof. Dr. med. Thomas Linder | HNO LUKS |
HNO LUKS, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.02.2024 | |||||||
| 2024-00220 | ADE (adverse drug event) Hospitalization – inadäquate Medikation bei geriatrisch hämatologisch-onkologischen Patientinnen und Patienten | personal data/biological material | monocentric | Dr. med. Wiebke Rösler | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 25.06.2024 | |||||||
| 2024-00219 | Clinical, radiological and patient related outcomes in Legg-Calvé-Perthès disease. A monocentric case series | non clinical, involving persons | monocentric | A | Dre Sophie Merkaert | CHUV - DFME - Chirurgie |
Hôpital de l’enfance, Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.05.2024 | yes | |||||
| 2024-00218 | Evaluation of the electrical and mechanical properties of the glioblastoma microenvironment and the tumor interactions with existing neural circuits | personal data/biological material | monocentric | Prof. Dr. Dr. G. Hutter | NCH Basel |
NCH Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.02.2024 | |||||||
| 2024-00217 | Brachytherapy versus surgery in localized squamous cell carcinoma of the lip: a propensity-matched survival analysis | non clinical, involving persons | monocentric | A | PD Dr. med. Olgun Elicin | Inselspital |
Universitätsklinik für Radio-Onkologie, Bern |
Kantonale Ethikkommission Bern | 03.07.2024 | ||||||
| 2024-00216 | Processing Spoken Language and Cognition in Chronic Subjective Tinnitus | non clinical, involving persons | monocentric | A | Prof. Dr. rer. nat. Martin Meyer | Universität Zürich |
Universität Zürich, Zürich |
Kantonale Ethikkommission Zürich | 23.04.2024 | ||||||
| 2024-00215 | CAIN457E22101 - An open-label, multicenter study to evaluate the pharmacokinetics, safety and tolerability of intravenous secukinumab infusion in adults with giant cell arteritis (GCA) or polymyalgia More ... | clinical trial | drugs | phase 1 | multicentric | C | Prof. Dr. med. Thomas Daikeler | Novartis Pharma Schweiz AG |
Universitätsspital Basel, Basel Inselspital Bern - Universitätsspital, Bern Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 04.04.2024 | |||
| 2024-00214 | DAREON-8: A Phase I, open-label, dose escalation and expansion trial of repeated intravenous infusions of BI 764532 combined with standard of care (platinum, etoposide, and anti-PDL1) in patients with More ... | clinical trial | drugs | phase 1 | monocentric | C | Dr. Hasna Bouchaab | Boehringer Ingelheim International GmbH |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.08.2024 | ||||
| 2024-00213 | A RANDOMIZED, 2-ARM, PHASE 3 STUDY OF ELRANATAMAB (PF-06863135) VERSUS LENALIDOMIDE IN PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA AFTER UNDERGOING AUTOLOGOUS STEM-CELL TRANSPLANTATION | clinical trial | drugs | phase 3 | multicentric | C | Jeroen Goede | Pfizer GmbH |
Kantonsspital Winterthur, Winterthur Inselspital Bern, Universitätsklinik für Medizinische Onkologie, Bern Zentrum für Onkologie/Hämatologie Kantonsspital Baden AG, Baden Département d'oncologie UNIL- More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.05.2024 | |||
| 2024-00212 | Testing the effectiveness of the culturally adapted skills training START NOW to reduce mental health problems in adolescent refugees | clinical trial | other clinical trials | monocentric | A | Dr. phil. Donja Brunner | University Psychiatric Clinics Basel |
University Psychiatric Clinics Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.03.2024 | yes | ||||
| 2024-00210 | Seizure, Cognitive, and Functional Outcomes of Pediatric Epilepsy treated with Ketogenic Diet Therapy | personal data/biological material | monocentric | Prof. Dr. med. Georgia Ramantani, PhD | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital, Zürich |
Kantonale Ethikkommission Zürich | 26.03.2024 | |||||||