| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-02448 | Biomechanical Analysis of Torque Application in Novel Biodegradable Cannulated Compression Screws for Distal Finger Joint Fusion and Metacarpal Fractures | deceased persons | monocentric | Herr Dr. med. Urs Hug | Kantonsspital Luzern |
Kantonsspital Luzern, Klinik für Hand- und plastische Chirurgie, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.02.2025 | |||||||
| 2024-02447 | Evaluation of a clinical respiratory muscle strength training program and estimation of training improvements in persons with spinal cord injury | personal data/biological material | monocentric | Dr. Gabi Mueller | Swiss Paraplegic Research |
Swiss Paraplegic Research, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.12.2024 | |||||||
| 2024-02445 | A retrospective analysis of the potential use of Artificial Intelligence in Swiss population-based breast cancer screening programs, to explore improvements in quality and workflow efficiency within S More ... | personal data/biological material | monocentric | Dr. med. Chris de Wolf | Team Radiologie Plus |
Team Radiologie Plus, Münsterlingen |
Ethikkommission Ostschweiz (EKOS) | 06.02.2025 | |||||||
| 2024-02444 | H2O – Hydration to be Optimized with a low-sodium beverage | clinical trial | other clinical trials | monocentric | A | Dr. Carolina Stambolsky | Nestlé Institute of Health Sciences |
Clinical Innovation Lab (Nestlé Research), Lausanne-26 |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.03.2025 | Study has ended | ||||
| 2024-02443 | Feasibility of dietary advice on spices and foods with glucose-lowering effect in routine care in women with gestational diabetes mellitus (GDM): “MySpicyPregnancy” pilot study | non clinical, involving persons | monocentric | A | Pre Jardena Puder | CHUV - DFME - Obstétrique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 04.02.2025 | ||||||
| 2024-02441 | CYTB323I12201_A Phase 2, randomized, open-label, controlled study to evaluate the efficacy and safety of rapcabtagene autoleucel versus comparator in participants with severe active Granulomatosis wit More ... | clinical trial | gene therapy | multicentric | C | Dr. Lisa Christ |
Universitätsspital Bern, Bern Universitätsspital Basel, Basel |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.05.2025 | |||||
| 2024-02440 | Fluid Challenge in Intensive Care: a worldwide global inception cohort study. The FENICE II study. | personal data/biological material | multicentric | Prof. Dr. Sascha David | IRCCS Humanitas Research Hospital |
Insitut für Intensivmedizin, UniversitätsSpital Zürich, Zurich KantonsSpital Olten, Olten Hôpitaux universitaires de Genève, Geneva Kantonsspital St. Gallen, St. Gallen Kantonsspital Frauenfeld, Fraue More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico can More ... | 15.04.2025 | ||||||
| 2024-02439 | CORNERSTONE: A ProspeCtive ObseRvatioNal Study of Atogepant Effectiveness in Routine Clinical Practice | non clinical, involving persons | multicentric | A | Prof. Dr. Chiara Zecca | AbbVie AG |
Ente Ospedaliero Cantonale, Lugano Inselspital, Bern Zurzach Care AG, Bad Zurzach NeuroPraxis Birseck, Reinach Basel DYA Swiss Institute SA, Lugano CHUV, Lausanne Hopital du Valais, Sion Kopfwehzentru More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... | 11.04.2025 | |||||
| 2024-02438 | Retrospective international multicenter study comparing polyurethan versus non-polyurethan covered implants in immediate prepectoral implant-based breast reconstruction in the setting of postmastectom More ... | personal data/biological material | multicentric | Prof. Dr. Walter Weber | Universitätsspital Basel (USB) |
Universitätsspital Basel, Basel Kantonsspital Baden, Baden Tumor-und BrustZentrum Ostschweiz, St. Gallen University Hospital Zurich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 14.01.2025 | ||||||
| 2024-02435 |
Development and application of a non-invasive test to monitor the excretion of bicarbonate in urine after oral intake of a test dose of NaHCO3- |
clinical trial | other clinical trials | multicentric | A | Prof. Dr. med. Alexander Möller | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital Zürich, Zürich University Hospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 08.07.2025 | yes | |||
| 2024-02434 | Hyponatremia in severe hypothyroidism (“The HYPO2 study”) | personal data/biological material | monocentric | Dr. Julia Beck | University Hospital Basel |
University Hospital Basel, Department of Endocrinology, Diabetes and Metabolism, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.01.2025 | |||||||
| 2024-02433 | Validation of the PAncreatic Surgery Composite Endpoint (PACE) | personal data/biological material | monocentric | Christoph Kümmerli | Clarunis University Digestive Health Care Center Basel |
Clarunis Digestive Health Care Center, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.12.2024 | |||||||
| 2024-02432 |
SAKK 16/xx_gender Sex specific differences in safety and efficacy outcomes in operable Stage III Non-Small Cell Lung Cancer Retrospective analysis of the trials SAKK 16/96, 16/00, 16/01, 16/08 and More ... |
personal data/biological material | monocentric | PD Dr. med. Sabine Schmid | SAKK |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 07.01.2025 | |||||||
| 2024-02431 | Different TGF-ß deposition of damaged and undamaged cartilage- Effect of Loading with Shear and Compression | personal data/biological material | multicentric | Prof. Dr. med. Sandro Fucentese | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich AO Research Institut Davos, Davos Platz |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 03.10.2025 | ||||||
| 2024-02429 | The expression of inflammatory and skin barrier markers in Darier disease and Hailey-Hailey disease | personal data/biological material | monocentric | Dr. med. et phil. Susanne Radonjic |
Klinik für Dermatologie, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 28.01.2025 | ||||||||
| 2024-02428 | Vertebropexy in sagittal and frontal spinal deformities – a cadaver study | deceased persons | monocentric | PD Dr. Jonas Widmer | Universitätsklinik Bvalgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 15.04.2025 | |||||||
| 2024-02427 | Enhanced Vision and Imaging Test for Enabling Treatment Trials in Early and Intermediate AMD | non clinical, involving persons | monocentric | A | PD Dr. med. Maximilian Pfau | Eye Clinic, University Hospital Basel |
Eye Clinic, University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.01.2025 | ||||||
| 2024-02425 | SCIP / SIEA and PAP: The New Workhorse Flaps in Soft-Tissue Reconstruction | personal data/biological material | monocentric | Dr. med. Alberto Franchi | Hand- und Plastische Chirurgie, Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 04.04.2025 | |||||||
| 2024-02423 | Validation of a 3D motion analysis protocol with an instrumented game to evaluate upper limb impairments in children with neuromotor disorders | clinical trial | other clinical trials | monocentric | A | Dre Marine Cacioppo | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.02.2025 | yes | ||||
| 2024-02422 | Endoscopic submucosal dissection for colorectal lesions: outcomes in a Swiss communitiy hospital | personal data/biological material | monocentric | Prof. Dr. med. Radu Tutuian | Bürgerspital Solothurn |
Bürgerspital Solothurn, Solothurn |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.12.2024 | |||||||