| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2016-01910 | Facilitation through Aggrastat or cangrelor Bolus and infusion Over prasugreL: a mUlticenter randomized open-label trial in patientS with ST-elevation myocardial inFarction referred for primAry percut More ... | clinical trial | drugs | phase 4 | monocentric | A | Prof. Dr. Marco Valgimigli | University Clinic for Cardiology |
University Clinic for Cardiology Inselspital, 3010 Bern |
Kantonale Ethikkommission Bern | 26.01.2017 | Study has ended | |||
| 2016-01909 | Accuracy of patient specific template-guided vs. free-hand fluoroscopically controlled pedicle and lateral mass screw placement in the subaxial cervical spine: a randomized cadaveric study | deceased persons | monocentric | PD Dr. med. MPH Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.12.2016 | Study has ended | ||||||
| 2016-01908 | Identifikation von Biomarkern für krankheitsbedingte Komplikationen bei Patienten mit myeloproliferativen Neoplasien | personal data/biological material | monocentric | Dr. med. Alexandre Theocharides | University Hospital Zurich, Division of hematology |
University Hospital Zurich, Division of hematology, Zurich |
Kantonale Ethikkommission Zürich | 08.12.2016 | |||||||
| 2016-01907 | INCB 54828-203: A Phase 2, Open-Label, Monotherapy, Multicenter Study to Evaluate the Efficacy and Safety of INCB054828 in Subjects With Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement | clinical trial | drugs | phase 2 | multicentric | B | PD Dr. Balabanov Stefan | Incyte Corporation |
University Hospital Zurich, 8091 Zurich INSELSPITAL, University Hospital Bern, 3010 Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 19.06.2017 | Study has ended | ||
| 2016-01906 | A Prospective, Multi-Center, Randomized, Concurrently-Controlled Clinical Study of the BARD COVERA Arteriovenous (AV) Stent Graft in the Treatment of Stenosis in the Venous Outflow of AV Fistula Acces More ... | clinical trial | medical devices | monocentric | C3 | Prof. Dr. med. Thomas Pfammatter | BD / Bard Peripheral Vascular, Inc. |
UniversitätsSpital, Zürich |
Kantonale Ethikkommission Zürich | 09.02.2017 | Study has ended | ||||
| 2016-01905 | Retrospektive Studie über Häufigkeit von maligne Hyperthermie-verursachenden Ryanodin-Rezeptor Typ 1 Mutationen in der Schweiz und deren mögliche metabolische Wirkung auf den Body Mass Index der betro More ... | personal data/biological material | monocentric | PD Dr. Oliver Bandschapp | University Hospital Basel |
Department Anästhesie, Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.12.2016 | |||||||
| 2016-01904 | A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician’s Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent | clinical trial | drugs | phase 3 | monocentric | C | Dr. Nicolas Bonadies | Onconova Therapeutics, Inc. |
Inselspital, Universitätsklinikum, Bern |
Kantonale Ethikkommission Bern | 15.06.2017 | Study has ended | |||
| 2016-01903 | Kinematische und elektromyographische Analysen eines dynamischen Sitzsystems bei gesunden Erwachsenen | non clinical, involving persons | monocentric | A | Lars Donath | Department of Sport, Exercise and Health |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.12.2016 | Study has ended | |||||
| 2016-01902 | Comparison of iterative reconstruction algorithms to optimize image quality of cerebral computed tomography angiography in patients with intracranial aneurysms | personal data/biological material | monocentric | Dr.med. Vincent Dunet | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.12.2016 | Study has ended | ||||||
| 2016-01901 | Serum neurofilament light chain levels: a biomarker for prediction of neurological disability in multiple sclerosis | personal data/biological material | monocentric | Chiara Zecca | Ospedale Regionale di Lugano |
Ospedale Regionale di Lugano, Lugano |
Comitato etico cantonale Ticino | 16.12.2016 | |||||||
| 2016-01900 |
SAKK 19/16 Binimetinib, pemetrexed and cisplatin, followed by maintenance with binimetinib and pemetrexed, in patients with advanced non-small cell lung cancer with KRAS mutations. A multicenter phas More ... |
clinical trial | drugs | phase 1 | multicentric | C | PD Dr. med. Martin Früh | SAKK |
Kantonsspital St. Gallen, St. Gallen Universitätsspital Basel, Basel IOSI Ospedale Regionale di Bellinzona e Valli, Bellinzona Kantonsspital Graubünden, Chur |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 28.02.2017 | Study has ended | ||
| 2016-01899 | Vergleich des klinischen Verlaufs von Infektionen mit unterschiedlichen Klebsiella Arten von 2014 - 2016 MASTERTHESE | personal data/biological material | monocentric | PD Dr. med. Dr. phil. Adrian Egli, FAMH | Clinical Microbiology |
Clinical Microbiology University Hospital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.12.2016 | |||||||
| 2016-01898 | Retrospektive Datenanalyse von häuslicher Gewalt von 2006 bis 2016 im universitären Notfallzentrum des Inselspitals Bern | personal data/biological material | monocentric | Aristomenis Exadaktylos | UNZ, Inselspital |
UNZ, Inselspital, Bern |
Kantonale Ethikkommission Bern | 18.01.2017 | |||||||
| 2016-01897 | Primary graft dysfunction in lung transplantation | personal data/biological material | monocentric | Prof. Dr. med. Ilhan Inci | Thoraxchirurgie Universitätsspital Zürich |
Thoraxchirurgie Universität Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.02.2017 | |||||||
| 2016-01895 |
CLCZ696G2301- A multi-center, randomized, double-blind, active-controlled, parallel-group Phase 3 study to evaluate the efficacy and safety of LCZ696 compared to ramipril on morbidity and mortality i More ... |
clinical trial | drugs | phase 3 | multicentric | B | PD Dr. med. Lukas Hunziker Munsch | Novartis Pharma Schweiz AG |
Inselspital Bern, Bern Luzerner Kantonsspital, Luzern Kantonsspital St. Gallen, St. Gallen Cardiocentro Ticino, Lugano |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Comitato etico cantonale Ticino | 01.02.2017 | Study has ended | ||
| 2016-01894 | CHIld-Parent Immunisation Survey – CHIPS | non clinical, involving persons | monocentric | A | Prof. Dr. med. Ulrich Heininger | UKBB |
UKBB, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.11.2016 | yes | Study has ended | ||||
| 2016-01893 |
International, multicenter, prospective registry to collect data of treatment patterns in patients with bilateral condylar fracture (BCFx) of the mandible |
non clinical, involving persons | multicentric | A | Dr. Florian Thieringer | AO Foundation / AO ITC |
Universitätsspital Basel, Basel Klinik für Mund-, Kiefer- und Gesichtschirurgie, UniversitätsSpital Zürich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 12.12.2016 | |||||
| 2016-01892 |
SWISS HEART FAILURE INITIATIVE (SWISS-HFI) A quality initiative of the Heart Failure Working Group of the Swiss Society of Cardiology (SSC). The mission of this initiative is to represent the quali More ... |
non clinical, involving persons | monocentric | A | Professor Roger Hullin | University Hospital Lausanne |
University Hospital Lausanne (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.05.2017 | yes | Study has ended | ||||
| 2016-01891 | Long-term follow-up of carotid artery endarterectomy with bifurcation advancement in the era of best medical treatment with statins and beta blockers. | non clinical, involving persons | monocentric | A | PD Dr. Zoran Rancic | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 07.02.2017 | ||||||
| 2016-01890 | SPECT/CT for assessment of patellar tracking and in-vivo loading after total knee arthroplasty | personal data/biological material | monocentric | PD Dr. med. Michal Hirschmann | Kantonsspital Baselland, Department für Orthopädie und Traumatologie des Bewegungsapparates |
Kantonsspital Baselland, Bruderholz |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.12.2016 | |||||||