| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-D0004 | Safety and feasibility of ultrasound-assisted non-invasive measurement of compressibility of the thyroid gland in patients scheduled for surgical removal | clinical trial | medical devices | monocentric | C2 | PD Dr. med. Urs Borner | Insel Gruppe |
Insel Gruppe, Bern |
Kantonale Ethikkommission Bern | 28.05.2025 | |||||
| 2025-D0003 | Development of Artificial Intelligence algorithms from respiratory sounds recorded with the Pneumoscope in children and adolescents with wheezing disorders. | clinical trial | medical devices | monocentric | C2 | Isabelle Ruchonnet-Métrailler | Geneva University Hospitals |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 05.06.2025 | yes | ||||
| 2025-D0001 | Immediate loading of immediate single implants with a definitive crown in premolar regions: A prospective single-arm clinical trial | clinical trial | medical devices | monocentric | A1 | Dr. Med. Dent. Duygu Karasan | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 07.05.2025 | |||||
| 2025-02655 | Accuracy of Maxillary Positioning in Semi-Guided vs. Splint-Based Orthognathic Surgery | personal data/biological material | monocentric | Prof. Dr. mult. Florian M. Thieringer | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.02.2026 | |||||||
| 2025-02654 | Impact of clinical context information on the diagnostic accuracy of Large Language Models (LLMs) in radiologic image interpretation: a comparative evaluation of proprietary an open multimodal models | personal data/biological material | monocentric | Prof. Dr. med. T. Niemann, LA Kardiovaskuläre & Thorakale Radiologie |
Radiologie Kantonsspital Baden, 5404 Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.01.2026 | ||||||||
| 2025-02653 |
Extended interval dosing treatment with Anti-CGRP(R) Monoclonal Antibodies in Migraine Prophylaxis (EXTRA-M Study) |
non clinical, involving persons | monocentric | A | Prof. dr.ssa med. Chiara Zecca | Ente Ospedaliero Cantonale, Ospedale Regionale di Lugano |
Ente Ospedaliero Cantonale, Ospedale Regionale di Lugano, Lugano |
Comitato etico cantonale Ticino | 17.02.2026 | ||||||
| 2025-02650 | Tumor microenvironment transcriptomic profiling of non-melanoma skin cancer in solid organ transplant recipients versus non-transplant patients: a single-centre prospective observational cohort study | non clinical, involving persons | monocentric | A | Dr.med. Alexandra Junge |
Universitätsklinik für Dermatologie, Bern |
Kantonale Ethikkommission Bern | 09.02.2026 | |||||||
| 2025-02645 | Textbook outcome on recovery after colorectal surgery within an ERAS program, a retrospective study | personal data/biological material | monocentric | Prof. Dr.med Dimitri Christoforidis | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 21.01.2026 | |||||||
| 2025-02644 | Histological Mapping of the Extensor Hood Central Slip in Zone 3 and 4 | deceased persons | monocentric | Herr PD Dr. med. Thomas Giesen | Luzerner Kantonsspital |
Kantonsspital Luzern, Klinik für Hand- und plastische Chirurgie, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.03.2026 | |||||||
| 2025-02640 | Ventilatory efficiency during exercise in chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH) pre- and post-treatment. | personal data/biological material | monocentric | Prof Dr med Esther Irene Schwarz | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 06.03.2026 | |||||||
| 2025-02638 | Switching to the biosimilar ranibizumab-nuna for the intravitreal treatment of retinal diseases – a real-world study | personal data/biological material | monocentric | PD Dr. med. Pascal Knecht-Bösch | Augenklinik Wettingen |
Augenklinik Wettingen, Wettingen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.01.2026 | |||||||
| 2025-02637 | Cardiac Safety of anti-HER2 treatment in HER2-Positive and HER2-low Breast Cancer patients: Identifying Low- and High-Risk Patients for Echocardiographic Follow-up Simplification. | personal data/biological material | monocentric | Dre Sarah Hugelshofer | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.02.2026 | |||||||
| 2025-02636 | Blocking online alcohol exposure with a browser plugin: a proof-of-concept mixed methods, pilot randomized controlled trial | clinical trial | other clinical trials | monocentric | A | Nicolas Bertholet | Centre hospitalier universitaire vaudois |
Centre hospitalier universitaire vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.03.2026 | |||||
| 2025-02633 | Fattibilità ed efficacia di un intervento psicoterapeutico EMDR con procedure addizionali (EMDR Toolbox) nel miglioramento del benessere psicologico di pazienti affetti da diagnosi di malattia oncolog More ... | clinical trial | other clinical trials | monocentric | A | Paola Arnaboldi | Lega cancro Ticino |
Lega cancro Ticino, Bellinzona |
Comitato etico cantonale Ticino | 02.03.2026 | |||||
| 2025-02631 | Fluorescence visualization and Image Quality Evaluation of Digital visualization of suspected Grade III and/or IV Gliomas during Neurosurgery (Leica GLOW400). | non clinical, involving persons | monocentric | A | Prof. Dr. med. Raphael Guzman | Leica Microsystems (Schweiz) AG |
University Hospital Basel, Department of Neurosurgery, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.02.2026 | ||||||
| 2025-02629 | 3D Morphometric Analysis of the Transnasal Access Pathway to the Sphenopalatine Foramen Using CT scans and 3D Slicer | personal data/biological material | monocentric | Prof. Dr. med Michael Soyka | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 10.03.2026 | |||||||
| 2025-02628 | A retrospective analysis of postoperative complications in sinus surgery | personal data/biological material | monocentric | Prof. Dr. med Michael Soyka | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 10.03.2026 | |||||||
| 2025-02627 | Evaluating a novel 16-week psychiatric day-clinic early intervention program for adolescents (FIT = FrühInterventionsTagesklinik) | personal data/biological material | monocentric | Prof. Dr. med. Philipp Sterzer | University Psychiatric Clinics (UPK) Basel |
University Psychiatric Clinics (UPK) Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.01.2026 | |||||||
| 2025-02621 | Impact of Homologous Recombination Repair Gene Alterations on Outcomes in Metastatic Urothelial Carcinoma Treated with First-Line Enfortumab Vedotin plus Pembrolizumab | personal data/biological material | multicentric | Dr. med. Fabio Turco | Istituto Oncologico della Svizzera Italiana (IOSI) |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona Inselspital, Bern St. Claraspital, Basel Hôpitaux universitaires de Genève (HUG), Geneve HOCH Health Ostschweiz, Kantonsspital St.Gallen, More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche G More ... | 09.03.2026 | ||||||
| 2025-02620 | Non-interventional, prospective, multicenter study to evaluate treatment satisfaction, treatment preference, quality of life, and tolerability under treatment with Briumvi® for relapsing forms of mult More ... | non clinical, involving persons | multicentric | A | Prof. Dr. Dr. Cristina Granziera | Neuraxpharm Arzneimittel GmbH |
Universitätsspital Basel, Klinik und Poliklinik für Neurologie, Basel Kantonsspital Aarau, Klinik für Neurologie, Aarau Neuropraxis Wohlen, Wohlen Luzerner Kantonsspital, Klinik für Neurologie und Neu More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 23.02.2026 | |||||