| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-02069 | Sex Disparities in Sudden Cardiac Death | personal data/biological material | monocentric | Katarzyna Michaud | UNIL - URMF |
University Center of Legal Medicine, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.11.2025 | |||||||
| 2025-02068 | Efficacy of Difluprednate Eye Drops in the Treatment of Postsurgical Cystoid Macular Edema | personal data/biological material | monocentric | Professor Stephan Michels |
Augenklinik Zürich West, Zürich |
Kantonale Ethikkommission Zürich | 30.01.2026 | ||||||||
| 2025-02067 |
EORTC PROLoNg PROLoNg: Pembrolizumab and Radiotherapy for OLigometastatic squamous cell carcinoma of the head and Neck: a randomized phase III study |
clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Panagiotis Balermpas | EORTC |
Universitätsspital Zürich, Zürich Inselspital Bern, Bern Kantonsspital Aarau, Aarau Luzerner Kantonsspital, Luzern Universitätsspital Basel, Basel HOCH Health Ostschweiz, St. Gallen IOSI - Istituto On More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 20.01.2026 | |||
| 2025-02066 | CLOU064P12301 - A randomized, double-blind, placebo-controlled Phase III study to evaluate the efficacy and safety of remibrutinib in patients with secondary progressive multiple sclerosis | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med. Raphaël Bernard-Valnet | Novartis Pharma Schweiz AG |
CHUV - Service de neurologie, Lausanne Inselspital - Universitätsklinik für Neurologie, Bern University Hospital Basel, Basel |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 03.02.2026 | |||
| 2025-02065 | Neurofilament light chain bei der ALS (NfL-ALS) | non clinical, involving persons | monocentric | A | Prof. Markus Weber | Charité Berlin |
ALS Clinic/Muskelzentrum , Kantonsspital St. Gallen, Sankt Gallen |
Ethikkommission Ostschweiz (EKOS) | 22.01.2026 | ||||||
| 2025-02064 | Localization of pseudarthroses following conservatively treated blunt thoracic trauma. | personal data/biological material | monocentric | Dr. med. Michail Galanis | Inselspital Bern |
Department for thoracic surgery, Bern |
Kantonale Ethikkommission Bern | 04.12.2025 | |||||||
| 2025-02063 | GAIT-NORM: Normative Gait Data Collection in Healthy Volunteers Using Wearable Sensors | non clinical, involving persons | monocentric | A | Prof. Dr. med. Roger Kalla | Inselspital, University Hospital Bern, Dept. of Neurology |
Universitätsklinik für Neurologie, Inselspital, Bern, Bern |
Kantonale Ethikkommission Bern | 07.04.2026 | ||||||
| 2025-02061 | Potential risk indicators of implant loss: a university-representative case control study | personal data/biological material | monocentric | Clemens Raabe | Klinik für Oralchirurgie und Stomatologie |
Klinik für Oralchirurgie und Stomatologie, zmk Bern, Bern |
Kantonale Ethikkommission Bern | 03.12.2025 | |||||||
| 2025-02060 | TeleEPI – Integrated care pathway for people with epilepsy based on an unobtrusive AI-powered telemedical system | non clinical, involving persons | monocentric | A | Prof Philippe Ryvlin | CHUV - DNC - Neurologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.08.2026 | ||||||
| 2025-02059 | Local and systemic safety and tolerability of ascending doses of TOP-N53, a nitric oxide (NO)-releasing phosphodiesterase-5 (PDE5) inhibitor, administered topically, on wound in patients with digital More ... | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. med. Dr. rer. nat. Ulrich Gerth | Topadur Pharma AG |
Reha Rheinfelden, Rheinfelden University Hospital Zürich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 26.11.2025 | |||
| 2025-02057 | Hold your breath – an attempt at a clinically relevant classification of periodic breathing in children | personal data/biological material | monocentric | Prof. Dr. med. Daniel Trachsel |
Universitäts Kinder-Spital beider Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.04.2026 | ||||||||
| 2025-02056 | TRITON-PN: A Phase 3, Global, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Nucresiran in Patients with Hereditary Transthyretin-Mediated Amyloidosis with Polyneuropathy (hATTR-P More ... | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. med. Tatiana Bremova-Ertl | Alnylam Pharmaceuticals, Inc. |
Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 20.08.2026 | ||||
| 2025-02055 | Outcome after ileo-pouch anal anastomosis (IPAA) | non clinical, involving persons | monocentric | A | Pr MD Dieter Hahnloser | CHUV - Chirurgie viscérale |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.10.2025 | ||||||
| 2025-02054 | Prospective Global Platform to Evaluate and Enhance Cognitive and Functional Trajectories after Stroke | non clinical, involving persons | monocentric | A | Tolga Dittrich, MD PhD | Hamilton Health Sciences |
Department of Neurology, HOCH Cantonal Hospital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 19.03.2026 | ||||||
| 2025-02053 | A Double-Blind, Placebo-Controlled, Multicenter, Randomized Phase 2 Trial Evaluating the Efficacy and Safety of Felzartamab in Recipients of Kidney Transplants with Late Isolated Microvascular Inflamm More ... | clinical trial | drugs | phase 2 | monocentric | C | Dusan Harmácek | Biogen Idec Research Limited |
University hospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 03.02.2026 | ||||
| 2025-02052 | Reverse Cherry Picking in Large Randomized Controlled Trials - Results from the DISTAL Trial | personal data/biological material | multicentric | Prof. Dr. Marios-Nikos Psychogios |
Universitätsspital Basel, 4031 Basel Inselspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 08.12.2025 | |||||||
| 2025-02051 | Presenting signs and symptoms of congenital portosystemic shunts | personal data/biological material | monocentric | Prof. Valérie McLin | Geneva University Hospitals |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.10.2025 | |||||||
| 2025-02049 | Swiss COPD Cohort Study | non clinical, involving persons | multicentric | A | Prof. Dr. med. Jörg Daniel Leuppi | Kantonsspital Baselland, Klinische Forschung |
Kantonsspital Baselland, Klinische Forschung, Liestal Kantonsspital Aarau, Aarau Universitätsspital Basel, Basel Hôpitaux Universitaires de Genève (HUG), Genève HOCH Health Ostschweiz, Kantonsspital S More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 10.03.2026 | |||||
| 2025-02048 | TRI0394 - Evaluation of B7H4 Protein Expression And Heterogeneity by IHC in FFPE Tumor Samples following Therapy Intervention in Advanced Breast Cancer Population | personal data/biological material | monocentric | Ernesta Dammassa | Novartis Pharma AG - Biomedical Research |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.10.2025 | |||||||
| 2025-02047 | Tooth Structure Loss Across Contemporary Preparation Designs: A Retrospective 3-D STL Analysis of Anterior and Posterior Restorations | personal data/biological material | monocentric | PD Dr. med. dent. Pune Paqué | Universität Zürich |
Universität Zürich, Zürich |
Kantonale Ethikkommission Zürich | 28.11.2025 | |||||||