| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-01011 | Etat des lieux de la prescription de médicaments immunosuppresseurs dans un hôpital gériatrique | personal data/biological material | monocentric | Dr Kuntheavy Ing Lorenzini | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 02.09.2025 | |||||||
| 2025-01010 | Dying on venovenous and venoarterial extracoroporeal membrane oxygenation – a retrospective analysis of cause of death, medical decision-making at the end of life, role of treatment limitations and pa More ... | personal data/biological material | monocentric | Prof. Dr. med. Sascha David | Klinik und Poliklinik für Innere Medizin |
Institut für Intensivmedizin, Zürich |
Kantonale Ethikkommission Zürich | 26.09.2025 | |||||||
| 2025-01009 | Efficacy of sequential use of antibody-drug conjugates targeting Topoisomerase-1 (Trastuzumab Deruxtecan then Sacituzumab Govitecan or vice versa) in patients with locally advanced or metastatic HER2- More ... | personal data/biological material | monocentric | PD Dr. med. Khalil ZAMAN | Medical Oncology Department IUCT-Oncopole |
Lausanne University Hospital CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.07.2025 | |||||||
| 2025-01008 | Entwicklung der körperlichen Leistungsfähigkeit von vorpubertären und pubertären Kindern – eine Follow-up Studie | non clinical, involving persons | monocentric | A | Dr. sc. Ralf Roth | Department für Sport, Bewegung und Gesundheit, Universität Basel |
Department of Sport, Exercise and Health, University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.05.2025 | yes | |||||
| 2025-01007 |
The PROTECT Trial: PROpofol Titration to Enhance haemodynamiC sTability Multicentre single-blinded, expertise-based RCT comparing haemodynamic parameters between titration and conventional induction More ... |
clinical trial | other clinical trials | multicentric | A | Dr. med. Martin Dominik Lohri, MD | Universitätsspital Basel |
University Hospital Basel, Basel Kantonsspital Baden, Baden Kantonspital Olten SoH, Olten Kantonsspital Graubünden, Chur |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 27.06.2025 | ||||
| 2025-01006 | Fever Burden and Neurological Outcome in Traumatic Spinal Cord Injury | personal data/biological material | monocentric | PD Dr David Legouis | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 24.07.2025 | |||||||
| 2025-01005 | Phase I, Randomized, Placebo-Controlled Study on the Role of the LC-NA System in Experimental Sleep Fragmentation with Buccal Dexmedetomidine. | clinical trial | drugs | phase 1 | monocentric | C | PD Dr. med. Marina Herwerth | University of Zurich |
University of Zurich, Zürich |
Kantonale Ethikkommission Zürich | 12.12.2025 | ||||
| 2025-01004 | Pergoveris patients’ profile and outcome response measurement in IVF/ICSI autologous cycles (PERFORM) | personal data/biological material | multicentric | Prof. Dr. med. Alexandra Kohl Schwartz | Merck Healthcare KGaA |
Luzerner Kantonsspital, Luzern Kinderwunschzentrum Baden, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.06.2025 | ||||||
| 2025-01003 | Evaluation of Complex Cervical Deformity Surgery Using 3D-Printed Models: Radiological Criteria, Surgical Outcomes, and Planning Workflow | personal data/biological material | monocentric | Dr. med Juan Barges-Coll | CHUV - Chirurgie spinale |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.07.2025 | |||||||
| 2025-01002 | Psychometric validation of French version of the Adult Concentration Inventory (ACI) among clinical and non-clinical samples of French-speaking adults | non clinical, involving persons | multicentric | A | Jean Marie Vianney Bizimana | Psychiatric Hospital of the University of Basel |
Les Toises - Psychiatry and Psychotherapy Center in Fribourg, Fribourg Les Toises – Centre de psychiatrie et psychothérapie, Biel Les Toises – Centre de psychiatrie et psychothérapie, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.10.2025 | |||||
| 2025-01001 | US-Spine - Efficacy of ultrasound-guided paravertebral block versus standard pain management in patients presenting with acute low back pain, with or without radiculopathy, in an emergency department More ... | clinical trial | other clinical trials | monocentric | A | Dr. med. Eckehart Schöll | Universitätsspital Basel |
Emergency Department Bethesda Spital AG, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.10.2025 | |||||
| 2025-01000 | Registre sur les patients ayant souffert d'une Communication Interventriculaire (CIV) post-infarctus | personal data/biological material | monocentric | Prof Stéphane Noble | HUG |
HUG, GENEVE |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 31.07.2025 | |||||||
| 2025-00999 | A Phase 2 Multicenter, Randomized, Double-masked, Sham-controlled, Reference-arm Study to Evaluate Efficacy and Safety of ONL1204 in Patients With Geographic Atrophy (GA) Associated With Age-related M More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Dr. scient. med. Marion Munk | ONL Therapeutics, Inc. |
Augenarzt Praxisgemeinschaft Gutblick AG, Bern Vista Augenklinik Binningen, Binningen Swiss Visio Retina Research Center, Lausanne Hopital ophtalmique Jules Gonin, Lausanne Stadtspital Zurich Triemli, More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.09.2025 | |||
| 2025-00998 | Impact de l’âge maternel sur le déroulement de la grossesse et l’accouchement au CHUV : une étude comparative entre les patientes de moins de 20 ans et les patientes adultes ayant accouché au CHUV ent More ... | personal data/biological material | monocentric | Dre Martine Jacot-Guillarmod | CHUV - DFME - Division |
Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.07.2025 | |||||||
| 2025-00997 | Complications after Robot-Assisted Radical Cystectomy with Intracorporeal Diversion: A Comprehensive Guide for Surgeons | personal data/biological material | monocentric | PD Dr. med. Ashkan Mortezavi |
Unispital Basel Urologie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.05.2025 | ||||||||
| 2025-00996 | The relevance of immunoglobulin E (IgE) glycosylation in development and course of allergic reactions | personal data/biological material | monocentric | Prof. Dr. med. Marie-Charlotte Brüggen | Allergiestation, Dermatologische Klinik, Universitätsspital Zürich |
Allergiestation, Dermatologische Klinik, Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.08.2025 | |||||||
| 2025-00993 |
Dysfunction of the vascular system as promoter for cognitive decline: retinal vessel analysis in patients with mild cognitive impairment |
non clinical, involving persons | monocentric | A | Prof. Dr. med. Isabella Sudano | University Hospital Zurich Cardiology |
University Hospital Zurich, Cardiology, Zuerich |
Kantonale Ethikkommission Zürich | 26.09.2025 | ||||||
| 2025-00992 | Outcome of biventricular repair of hearts with a borderline left ventricle | personal data/biological material | monocentric | Professor Amir-Reza HOSSEINPOUR | CHUV - Chirurgie cardiaque |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.05.2025 | |||||||
| 2025-00991 | OPEN-LABEL PLACEBO IN PSYCHOTHERAPY – A FEASIBILITY STUDY | clinical trial | other clinical trials | monocentric | A | Prof Jens Gaab | University of Basel, Division of Clinical Psychology and Psychotherapy |
University of Basel, Division of Clinical Psychology and Psychotherapy, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.08.2025 | |||||
| 2025-00990 | HEM-iSMART: International proof of concept therapeutic Stratification trial of Molecular Anomalies in Relapsed or Refractory HEMatological malignancies in children | clinical trial | drugs | phase 1/2 | monocentric | C | Dr. Nastassja Scheidegger | Princess Máxima Center for Pediatric Oncology |
Universitäts-Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 15.07.2025 | yes | |||