| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-01151 | Days alive and out of hospital within 30 days of patients presenting with atrial fibrillation with rapid ventricular response at Luzerner Kantonsspital Emergency Department – retrospective review | personal data/biological material | monocentric | Prof. Dr. med. Michael Christ | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.07.2025 | |||||||
| 2025-01150 | La césarienne douce: un bénéfice pour tous? | non clinical, involving persons | monocentric | A | Dresse Corinne Grandjean | Hôpital cantonal Fribourg |
HFR Fribourg, Villars-sur-Glâne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.03.2026 | ||||||
| 2025-01149 | (ISA-SPY001) Phase 2 Platform Trial to Assess the Efficacy and Safety of Long-acting Antibodies as Single Agents and in Combinations for Moderately to Severely Active Ulcerative Colitis | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. med. Pascal Juillerat | Spyre Therapeutics, Inc. |
Intesto BE, Bern Clarunis – Universitäres Bauchzentrum Basel Universitätsspital Basel Petersgraben 4, 4031 Basel HOCH Health Ostschweiz Kantonsspital St.Gallen Gastroenterologie/Hepatologie Haus 03, 1 More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS) | 24.10.2025 | Study has ended | ||
| 2025-01147 | Relative Afferent Pupillary Defect (RAPD) neoscore validation | personal data/biological material | monocentric | Bruno Hauser | machineMD AG |
machineMD AG, Bern |
Kantonale Ethikkommission Bern | 26.08.2025 | |||||||
| 2025-01145 | Efficacy of Port-wine birthmarks treatment with a new long-pulse KTP laser: a retrospective study | personal data/biological material | monocentric | Dr. Paula Bonavia, MD | Margarethenklinik, University Hospital of Basel |
Margarethenklinik, University Hospital of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.07.2025 | |||||||
| 2025-01143 | Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Corinne Widmer | Stichting Hemato-Oncologie voor Volwassenen Nederland (HOVON) |
University Hospital Basel, Basel Inselspital Bern, Bern IOSI, Ospedale Regionale, Bellinzona Universitätsspital Zürich, Zurich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 16.10.2025 | |||
| 2025-01142 | KiBa – Kids in Balance: Clinical evaluation of the Pediatric Balance Scale assessment for a reliable use with impaired children | non clinical, involving persons | monocentric | A | MSc. Physiotherapist, Zorica Suica | Reha Rheinfelden |
Reha Rheinfelden, Rheinfelden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.06.2025 | yes | |||||
| 2025-01141 | Implant Accuracy of 3D Printed PEEK, Barium Sulphate PEEK and Titanium for Orbital Reconstruction | deceased persons | monocentric | MSc. Jokin Zubizarreta Oteiza | Univeristy Hospital Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.09.2025 | |||||||
| 2025-01140 | Effects of Weight loss Surgery and Obesity Management Medication on Patient-Reported Outcomes, Efficacy, and Safety in Grade II-III Obesity | non clinical, involving persons | monocentric | A | Dr. med. Pauline Aeschbacher | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 17.09.2025 | ||||||
| 2025-01138 | Arts and culture on prescription. The impact of cultural prescription on the health of the elderly population living in the Lugano region – A pilot project. | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Luca Gabutti | Università della Svizzera italiana / EOC |
Institute of Family Medicine, Lugano |
Comitato etico cantonale Ticino | 06.10.2025 | |||||
| 2025-01137 | Development of an in-vitro model to predict fecal microbiota transplantation outcomes in Clostridioides difficile infection using stool derived in-vitro communities | personal data/biological material | monocentric | Dresse Katerina-Tatiana Galperine, MER-PD | CHUV - Maladies Infectieuses |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.12.2025 | |||||||
| 2025-01135 | Valve testing with cardioplegia versus conventional water | personal data/biological material | multicentric | PD Dr. med. Héctor Rodriguez Cetina Biefer | USZ |
Universitätsspital Zürich, Zürich Stadtspital Triemli, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 02.09.2025 | ||||||
| 2025-01134 | Empathy and (self-)compassion to improve the quality of life of Parkinson’s disease patients and caregivers: an exploratory study | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Alain Kaelin | Istituto di Neuroscienze Cliniche della Svizzera Italiana |
Istituto di Neuroscienze Cliniche della Svizzera Italiana - EOC, Lugano |
Comitato etico cantonale Ticino | 02.09.2025 | |||||
| 2025-01133 | Outcomes of robotic-assisted repair of rectus diastasis: a retrospective observational study | non clinical, involving persons | monocentric | A | PD Dr.med Francesco Mongelli |
Chirurgia, Ospedale Regionale di Bellinzona e Valli, Bellinzona |
Comitato etico cantonale Ticino | 23.07.2025 | |||||||
| 2025-01131 | Modified technique of the Grisotti-flap for centrally located carcinomas of the breast | non clinical, involving persons | monocentric | A | PD Dr. med. univ. Christoph Tausch | Brust-Zentrum Zürich AG |
Brust-Zentrum Zürich, Zürich |
Kantonale Ethikkommission Zürich | 09.09.2025 | ||||||
| 2025-01130 | Is Autologous Fat Grafting a Safe Option for Women with Breast Cancer and Germline Pathogenic Variants in Relation to Cancer Recurrence Risk? (IOSI-SLIM-001: Safety of Lipofilling in Mammary cancer) | personal data/biological material | multicentric | MD Rossella Graffeo | IOSI |
IOSI Oncology Institute of Southern Switzerland, Bellinzona Kantonsspital Baden, BADEN Kantonsspital Luzern (LUKS), LUZERN Brust Zentrum, Zürich |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 05.12.2025 | ||||||
| 2025-01129 | Characterization of Cerebral Micro-Emboli Associated with Endovascular Procedures for Intracranial Aneurysms | personal data/biological material | monocentric | Dr Bruno BARTOLINI | CHUV - Radiodiagnostic et |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 04.11.2025 | |||||||
| 2025-01128 | Effects of neoadjuvant immunotherapy on anti-tumour immunity in hepatocellular carcinoma patients undergoing liver resection | clinical trial | drugs | phase 2 | monocentric | B | Prof. Christian Toso | HUG |
Geneva University Hospital, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.11.2025 | ||||
| 2025-01127 | An italian study of OligoMEtastatic uROthelial cancer treated with stereotactic body radiation therapy: the OMERO study | personal data/biological material | multicentric | Prof. Dr. med. Thomas Zili | IRCCS Istituto Clinico Humanitas |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona Inselspital Bern, Bern |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Bern | 04.12.2025 | ||||||
| 2025-01126 | Long-term outcomes of Trochleoplasty: A 20-25 years follow-up Study | non clinical, involving persons | monocentric | A | Prof. Dr. med. Sandro Fucentese | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 29.07.2025 | ||||||