| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-01493 | Outcomes of fecal microbiota (REBYOTA©) Therapy in Patients with Recurrent Clostridioides difficile Infection: Real-World Data from a Single Center in Switzerland | personal data/biological material | monocentric | Prof. Michael Scharl | Universitätsspital Zürich |
Universtiätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 10.10.2025 | |||||||
| 2025-01490 | Efficacy and Safety of Anticoagulation in Traumatic Cerebral Venous Sinus Thrombosis: A Retrospective Analysis | personal data/biological material | multicentric | PD Dr. med. Levin Häni | Universitätsklinik für Neurochirurgie |
Universitätsklinik für Neurochirurgie, Bern KSA Kantonsspital Aarau, Aarau |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.08.2025 | ||||||
| 2025-01489 |
Feasibility study of flow and pressure derived leakage quantification Prospective monocentric, non-randomized pilot study with 15 patients Short title: VITAL Valve Inspection for Tightness, Asse More ... |
non clinical, involving persons | monocentric | A | Dr. Emmanuel Zimmer | ARTORG Center for Biomedical Engineering Research |
Herzchirurgie, Bern |
Kantonale Ethikkommission Bern | 04.12.2025 | ||||||
| 2025-01488 | Comparative Analysis of ECT-Induced Seizure EEG Signatures in Humans and Mice | personal data/biological material | monocentric | Prof. Dr. med. Annette Brühl | UPK Basel |
UPK Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.07.2025 | |||||||
| 2025-01487 |
CHUV- DO-Lundin-PHENIX (SAKK 70/24) Open-label phase II clinical trial to test the efficacy of the combination of trimipramine and atezolizumab with bevacizumab in patients with recurrent glioblastom More ... |
clinical trial | drugs | phase 2 | multicentric | B | Prof. Dr. med. Andreas Hottinger | CHUV |
CHUV, Lausanne Inselspital Bern, Bern Universitätsspital Basel, Basel Kantonsspital Aarau, Aarau Luzerner Kantonsspital, Luzern HFR Fribourg, Fribourg Universitätsspital Zürich, Zurich |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.10.2025 | |||
| 2025-01486 | Residential exposure to agricultural pesticides and the risk of childhood cancer | personal data/biological material | monocentric | Prof. Dr. Ben Spycher | Institute of Social and Preventive Medicine |
University of Bern -- Institute of Social and Preventive Medicine, Bern |
Kantonale Ethikkommission Bern | 06.03.2026 | |||||||
| 2025-01485 | Microvascular Decompression Surgery for Neurovascular Compression Syndromes via a Burrhole Approach | personal data/biological material | monocentric | Dr. Jonathan Rychen | Universitätsspital Basel |
Universitätsspital Basel, Klinik für Neurochirurgie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.09.2025 | |||||||
| 2025-01484 | Electroconvulsive Therapy and cognitive impairment | personal data/biological material | monocentric | Dr. Else Schneider | UPK Basel |
Universitäre Psychiatrische Kliniken Basel, 4002 Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.09.2025 | |||||||
| 2025-01483 | Predicting the outcome of FAIS treatment using motion capture data | personal data/biological material | monocentric | Dr. sc. ETH Renate List | Schulthess Clinic |
Schulthess Clinic, Zürich |
Kantonale Ethikkommission Zürich | 19.09.2025 | |||||||
| 2025-01481 | Gait recovery following stroke and active therapy – a dose-response analysis. A retrospective cohort analysis of clinical data | personal data/biological material | monocentric | PhD / Clare / Maguire | REHAB Basel |
REHAB Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.12.2025 | |||||||
| 2025-01480 | Effects of a virtual reality-based exergaming intervention on cardiorespiratory fitness, depression severity, and health-related quality of life in inpatients with major depression | clinical trial | other clinical trials | multicentric | A | Prof. Dr. Markus Gerber | Department of Sport, Exercise and Health |
Department of Sport, Exercise and Health, University of Basel,, Basel Center for Affective, Stress and Sleep Disorders, Psychiatric Clinics Basel, Basel Psychiatry and Psychotherapy, Sonnenhalde, Base More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.09.2025 | ||||
| 2025-01477 | A randomized, double-blind, placebo-controlled, parallel-group, multicenter study of the efficacy and safety of depemokimab in adult participants with COPD with Type 2 inflammation | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Hans-Joachim Kabitz | GlaxoSmithKline Research & Development Limited |
Kantonsspital Aarau, Klinik für Pneumologie und Schlafmedizin, Aarau Universitätsspital Basel, Pneumologie, Basel Valens Rehaklinik Wald, Wald |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 19.11.2025 | |||
| 2025-01476 |
Surgical vs. Conservative Management of Thoracolumbar AO Type B Fractures in Ankylosed Spines: A Retrospective Study |
personal data/biological material | monocentric | Dr. Stefan Motov | Kantonsspital St. Gallen HOCH Ostschweiz |
Kantonsspital St. Gallen HOCH Ostschweiz, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 19.08.2025 | |||||||
| 2025-01475 | Artificial Intelligence versus Human Documentation in Pediatric Orthopedic Practice: A Comparative Quality Assessment of Medical History Summaries | personal data/biological material | monocentric | PD Dr. med. Carlo Camathias | Praxis Zeppelin |
Praxis Zeppelin, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 13.11.2025 | |||||||
| 2025-01474 | Étude rétrospective monocentrique sur les aspects radiologiques post-ablation par radiofréquence (RFA) dans les tumeurs neuroendocrines pancréatiques | personal data/biological material | monocentric | Prof. Dr. Clarisse Dromain | CHUV - Service de radiodiagnostic et radiologie interventionnelle |
CHUV - Service de radiodiagnostic et radiologie interventionnelle, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 05.08.2025 | |||||||
| 2025-01473 | Impact of lung volumetric adaptation of the transplanted lung on Baseline Lung Allograft Dysfunction and postoperative outcomes: a prospective comparative analysis using 3D-CT anatomical reconstructio More ... | personal data/biological material | monocentric | Prof. Thorsten Krueger | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.10.2025 | |||||||
| 2025-01470 | Development of the PTSD-iMPACT to Measure PTSD-Related Functional Impairment in Children and Adolescents – A Validation Study in Switzerland and Germany | non clinical, involving persons | multicentric | A | Dr. Lasse Bartels | University Children's Hospital Zurich |
University Children's Hospital Zurich, Zurich Kinder- und Jugendpsychiatrischer Dienst St.Gallen (KJPD), St. Gallen Psychiatrische Dienste Thurgau, Münsterlingen Psychiatrische Dienste Thurgau, Frauen More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 05.12.2025 | yes | ||||
| 2025-01469 | Neodream: Cry as a vocal biomarker supporting early screening of the risk of developing pathologies and neurodevelopmental disorders within infants' first months of life. | non clinical, involving persons | monocentric | A | Prof. Dr. med Cornelia Hagmann | ZOUNDREAM AG, Barcelona, Zweigniederlassung Basel (Schweiz) |
University Children's Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 28.11.2025 | yes | |||||
| 2025-01467 | Local anaesthesia for parapharyngeal / epiglottic abscess management: assessing feasibility and outcomes | personal data/biological material | monocentric | Dr. med. Cosima Riemenschnitter | University Hospital Zurich |
University Hospital Zurich, Department of Otorhinolaryngology, Head & Neck Surgery, Zürich |
Kantonale Ethikkommission Zürich | 07.10.2025 | |||||||
| 2025-01466 | Einfluss einer ketogenen Diät auf die [18F]-FDG Aufnahme im Gastrointestinaltrakt und in der Leber sowie im Fett- und Muskelgwebe: Retrospektive Auswertung klinischer [18F]-FDG-PET/CT-Daten. | personal data/biological material | monocentric | Prof. Irene A. Burger |
Kantonsspital Baden, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.07.2025 | ||||||||