| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-02460 | MK-3475-06E: A Phase 1/2 Open-Label, Umbrella Platform Design Study of Investigational Agents in Combination With Pembrolizumab (MK-3475) With or Without Chemotherapy in Participants With 1L Locally A More ... | clinical trial | drugs | phase 1/2 | multicentric | C | Dr. med. Sara Bastian | Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. |
Kantonsspital Graubünden, Chur Hôpitaux Universitaires de Genève (HUG), Genève |
Kantonale Ethikkommission Zürich | Commission Cantonale d'éthique de la recherche Genève (CCER) | 08.04.2025 | |||
| 2024-02459 | Real World Data Insights: Comparing Clinical and Urodynamic Outcomes in Neurogenic Detrusor Overactivity Treatment with 200 U BoNT-A versus 300 U and 300 U versus 400 U BoNT-A | personal data/biological material | monocentric | PD Dr. med. M. Hund-Georgiadis | REHAB Basel |
REHAB Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.12.2024 | |||||||
| 2024-02458 | Sensorimotor mismatch responses in freely moving humans - combining virtual reality and EEG recordings | non clinical, involving persons | monocentric | A | Dr Georg Keller | Friedrich Miescher Institute for Biomedical Research |
Friedrich Miescher Institute for Biomedical Research (FMI), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.01.2025 | ||||||
| 2024-02456 | A pilot study to develop personalised methods to quantify macronutrient intake and consumption | non clinical, involving persons | monocentric | A | Fabien Rebeaud | Liom Health AG |
Liom Health AG, Pfaeffikon SZ |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.12.2024 | Study has ended | |||||
| 2024-02455 | Branch pulmonary artery reconstruction with the bovine jugular vein Contegra® patch | personal data/biological material | monocentric | Prof. Dr. med. Hitendu Dave | Kinderspital Zürich |
Universitäts- Kinderspital Zürich – Eleonorenstiftung, Zürich |
Kantonale Ethikkommission Zürich | 17.01.2025 | |||||||
| 2024-02454 | A clinical review of two ultra-rare inborn errors of cobalamin metabolism: MTR and MTRR deficiency | personal data/biological material | monocentric | Prof Martina Huemer | University Childrens Hospital Zurich |
Kinderspital Zürich, Eleonorenstiftung, Zürich |
Kantonale Ethikkommission Zürich | 18.02.2025 | |||||||
| 2024-02453 | Understanding how we forget by non-invasive neuromodulation of memory | clinical trial | other clinical trials | monocentric | A | Dr. Shawn Hiew | University of Bern |
Institute for Psychology, University of Bern, Bern |
Kantonale Ethikkommission Bern | 17.02.2025 | |||||
| 2024-02452 | HBsAg Loss After Stopping Nucleoside Analogues in Patients with Chronic Hepatitis B (HALT-NUC Study) | non clinical, involving persons | multicentric | A | Prof. Dr. med. Beat Müllhaupt |
University Hospital Zurich, Zurich Clarunis Universitäres Bauchzentrum Basel, Basel |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.12.2025 | ||||||
| 2024-02450 | Comparison of diagnostic performance between AI-based T2-FLAIR-sequence and Double Inversion Recovery sequence concerning detection of cortical und juxtacortical lesions in patients with Multiple Scle More ... | personal data/biological material | monocentric | Prof. Dr. Cornelia Brendle | Team Radiologie Plus |
Team Radiologie Plus, Münsterlingen |
Ethikkommission Ostschweiz (EKOS) | 13.03.2025 | |||||||
| 2024-02449 | Promoting Auto-Inflammatory Diseases Diagnosis and Research in Adults (PAIDDRA) | non clinical, involving persons | monocentric | A | Dr Thomas Reygaerts | HFR Fribourg – Hôpital cantonal |
Clinique de rhumatologie, Hôpital Cantonal de Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 15.12.2025 | yes | |||||
| 2024-02448 | Biomechanical Analysis of Torque Application in Novel Biodegradable Cannulated Compression Screws for Distal Finger Joint Fusion and Metacarpal Fractures | deceased persons | monocentric | Herr Dr. med. Urs Hug | Kantonsspital Luzern |
Kantonsspital Luzern, Klinik für Hand- und plastische Chirurgie, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.02.2025 | |||||||
| 2024-02447 | Evaluation of a clinical respiratory muscle strength training program and estimation of training improvements in persons with spinal cord injury | personal data/biological material | monocentric | Dr. Gabi Mueller | Swiss Paraplegic Research |
Swiss Paraplegic Research, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.12.2024 | |||||||
| 2024-02445 | A retrospective analysis of the potential use of Artificial Intelligence in Swiss population-based breast cancer screening programs, to explore improvements in quality and workflow efficiency within S More ... | personal data/biological material | monocentric | Dr. med. Chris de Wolf | Team Radiologie Plus |
Team Radiologie Plus, Münsterlingen |
Ethikkommission Ostschweiz (EKOS) | 06.02.2025 | |||||||
| 2024-02444 | H2O – Hydration to be Optimized with a low-sodium beverage | clinical trial | other clinical trials | monocentric | A | Dr. Carolina Stambolsky | Nestlé Institute of Health Sciences |
Clinical Innovation Lab (Nestlé Research), Lausanne-26 |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.03.2025 | Study has ended | ||||
| 2024-02443 | Feasibility of dietary advice on spices and foods with glucose-lowering effect in routine care in women with gestational diabetes mellitus (GDM): “MySpicyPregnancy” pilot study | non clinical, involving persons | monocentric | A | Pre Jardena Puder | CHUV - DFME - Obstétrique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 04.02.2025 | Study has ended | |||||
| 2024-02441 | CYTB323I12201_A Phase 2, randomized, open-label, controlled study to evaluate the efficacy and safety of rapcabtagene autoleucel versus comparator in participants with severe active Granulomatosis wit More ... | clinical trial | gene therapy | multicentric | C | Dr. Lisa Christ |
Universitätsspital Bern, Bern Universitätsspital Basel, Basel |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.05.2025 | |||||
| 2024-02440 | Fluid Challenge in Intensive Care: a worldwide global inception cohort study. The FENICE II study. | personal data/biological material | multicentric | Prof. Dr. Sascha David | IRCCS Humanitas Research Hospital |
Insitut für Intensivmedizin, UniversitätsSpital Zürich, Zurich KantonsSpital Olten, Olten Hôpitaux universitaires de Genève, Geneva Kantonsspital St. Gallen, St. Gallen Kantonsspital Frauenfeld, Fraue More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico can More ... | 15.04.2025 | ||||||
| 2024-02439 | CORNERSTONE: A ProspeCtive ObseRvatioNal Study of Atogepant Effectiveness in Routine Clinical Practice | non clinical, involving persons | multicentric | A | Prof. Dr. Chiara Zecca | AbbVie AG |
Ente Ospedaliero Cantonale, Lugano Inselspital, Bern Zurzach Care AG, Bad Zurzach NeuroPraxis Birseck, Reinach Basel DYA Swiss Institute SA, Lugano CHUV, Lausanne Hopital du Valais, Sion Kopfwehzentru More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... | 11.04.2025 | |||||
| 2024-02438 | Retrospective international multicenter study comparing polyurethan versus non-polyurethan covered implants in immediate prepectoral implant-based breast reconstruction in the setting of postmastectom More ... | personal data/biological material | multicentric | Prof. Dr. Walter Weber | Universitätsspital Basel (USB) |
Universitätsspital Basel, Basel Kantonsspital Baden, Baden Tumor-und BrustZentrum Ostschweiz, St. Gallen University Hospital Zurich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 14.01.2025 | ||||||
| 2024-02435 |
Development and application of a non-invasive test to monitor the excretion of bicarbonate in urine after oral intake of a test dose of NaHCO3- |
clinical trial | other clinical trials | multicentric | A | Prof. Dr. med. Alexander Möller | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital Zürich, Zürich University Hospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 08.07.2025 | yes | |||