| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-00631 | Stereotactic multiple fraction radiotherapy for non-spine bone metastases | clinical trial | other clinical trials | monocentric | A | PD Dr. med. Robert Foerster | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 03.05.2022 | |||||
| 2022-00629 | Combining the advantages of 3D and 2D templating of total knee arthroplasty using a new ultra-low dose CT of the knee- a comparative study of accuracy. | personal data/biological material | monocentric | Prof. Dr. med. Sandro Fucentese | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 08.04.2022 | |||||||
| 2022-00628 | CANNABIS PILOT TRIAL IN THE CANTON OF BASEL-LANDSCHAFT IN ACCORDANCE WITH THE ORDINANCE ON PILOT TRIALS UNDER THE NARCOTICS LAW (BETMPV) | non clinical, involving persons | monocentric | A | Prof. Dr. Michael Schaub | Schweizer Institut für Sucht- und Gesundheitsforschung ISGF |
Schweizer Institut für Sucht- und Gesundheitsforschung ISGF, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.05.2022 | ||||||
| 2022-00621 | MK-1088-002: A Phase 1/Phase 2 Study to Evaluate the Safety and Tolerability of MK-1088 as Monotherapy and in Combination with Pembrolizumab in Participants with Advanced Solid Tumors | clinical trial | drugs | phase 1/2 | multicentric | C | PD Dr. med. Anastasios Stathis | Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona Kantonsspital St. Gallen, St. Gallen Kantonsspital Graubünden, Chur |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 28.06.2022 | |||
| 2022-00618 | Automatische und patientenspezifische 3D-MRT-Modelle von Hüftknochen, Hüftknorpel und Labrum für verbesserte chirurgische Entscheidungsfindung | personal data/biological material | monocentric | PD Dr. med. Simon D. Steppacher | Inselspital Bern |
Department für Orthopädie und Traumatologie, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 13.05.2022 | |||||||
| 2022-00616 | Harnessing the beneficial non-specific effects of measles-mumps-rubella vaccine on infection with unrelated pathogens and allergic diseases in children – a single-centre phase IV randomised controlle More ... | clinical trial | drugs | phase 4 | monocentric | A | Dr Laure PITTET | University Hospital of Geneva |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.05.2022 | yes | |||
| 2022-00614 | Comparaison du Bioactive Glass avec d’autres substituts osseux : autogreffe, allogreffe et antibiotiques locaux dans le traitement des pseudarthroses et ostéomyélites : une étude rétrospective. | personal data/biological material | monocentric | MD, PD, MERc Sylvain Steinmetz | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.04.2022 | |||||||
| 2022-00613 | A randomized, placebo-controlled, double-blind, monocenter, phase II trial to assess the efficacy of Calcium Dobesilate (CaD) vs. placebo on SARS-CoV-2 viral load amongst outpatients with COVID-19 | clinical trial | drugs | phase 2 | monocentric | B | MD Hervé Spechbach | Hôpitaux universitaire de Genève (HUG) |
Hôpitaux universitaire de Genève (HUG), Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 17.05.2022 | yes | |||
| 2022-00611 | Geschlechterspezifische Unterschiede in den Ursachen von Synkopen | personal data/biological material | monocentric | PD Dr. med. Dr. phil. Ksenija Slankamenac | Institut für Notfallmedizin |
Institut für Notfallmedizin, Zürich |
Kantonale Ethikkommission Zürich | 08.04.2022 | |||||||
| 2022-00610 | Biological behavior of sparsely and densely granulated GH secreting pituitary adenomas: a retrospective observational study of surgical series | personal data/biological material | monocentric | Dr Giulia Cossu | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.04.2022 | |||||||
| 2022-00609 | Comparison Of Accuracy Of Conventional Plating Vs. Intercus Plate In CARD Opening-Wedge Osteotomies Of Distal Radius Malunion | personal data/biological material | monocentric | Prof. Dr. med. Anderas Schweizer | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 12.04.2022 | |||||||
| 2022-00606 | Personalized IMMUNOtherapy in SEPsis: A multicentre and multinational, double-blind, double-dummy randomized clinical trial | clinical trial | drugs | phase 2 | monocentric | C | Prof. Thierry Calandra | Hellenic Institute for the Study of Sepsis |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 01.06.2022 | ||||
| 2022-00604 | Controllability and the interoception of breathing” (CITRO) | non clinical, involving persons | monocentric | A | Dr. Sandra Iglesias, PhD | UZH & ETHZ, Institut für Biomedizinische Technik, Translational Neuromodeling Unit |
Translational Neuromodeling Unit, Zurich |
Kantonale Ethikkommission Zürich | 06.05.2022 | ||||||
| 2022-00603 | SASCIA - Phase III postneoadjuvant study evaluating Sacituzumab Govitecan, an Antibody Drug Conjugate in primary HER2-negative breast cancer patients with high relapse risk after standard neoadjuvant More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Ursina Zürrer | GBG (German Breast Group) |
Kantonsspital Winterthur, Winterthur Brustzentrum, University Hospital Basel, Basel Kantonsspital St. Gallen, St. Gallen Brustzentrum Zürich, Zürich Kantonsspital Graubünden, Chur |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 24.06.2022 | |||
| 2022-00602 | A brief report of an interesting bone marrow finding in systemic mastocytosis | personal data/biological material | monocentric | Dr Vasiliki Papadopoulou | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.04.2022 | |||||||
| 2022-00595 | Streptococcus bovis bacteraemia : metastatic malignancies in the gut are also a gateway | personal data/biological material | monocentric | Sylvain Meylan | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 19.04.2022 | |||||||
| 2022-00593 | Evaluation of interactions between conventional and complementary medicine in healthcare circuits in Switzerland: a pilot observational study using health insurance billing data. | personal data/biological material | monocentric | Prof / Idris / Guessous | Hopitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 10.05.2022 | |||||||
| 2022-00592 | Visual Symptoms in Postural Tachycardia Syndrome | non clinical, involving persons | monocentric | A | Prof. Dr. med. Werner Z`Graggen | Universitätsklinik für Neurochirurgie und Neurologie |
Universitätsklinik für Neurochirurgie und Neurologie, Bern |
Kantonale Ethikkommission Bern | 24.06.2022 | ||||||
| 2022-00589 | Non-destructive assessment of articular cartilage: Can the device Arthro-BST be used safely and reliably under sterile conditions in hip and knee arthroplasty? | non clinical, involving persons | monocentric | A | Prof. Dr. med Moritz Tannast | HFR Fribourg - Cantonal Hospital |
HFR Fribourg - Cantonal Hospital, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.04.2022 | ||||||
| 2022-00588 | Smartphone app-assisted discontinuation of PPI – an interprofessional pilot study | non clinical, involving persons | monocentric | A | PD DR Isabelle Arnet | University of Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.06.2022 | ||||||