BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2022-00631 Stereotactic multiple fraction radiotherapy for non-spine bone metastases clinical trial other clinical trials monocentric A PD Dr. med. Robert Foerster Kantonsspital Winterthur Kantonsspital Winterthur, Winterthur
Kantonale Ethikkommission Zürich 03.05.2022
2022-00629 Combining the advantages of 3D and 2D templating of total knee arthroplasty using a new ultra-low dose CT of the knee- a comparative study of accuracy. personal data/biological material monocentric Prof. Dr. med. Sandro Fucentese Universitätsklinik Balgrist Universitätsklinik Balgrist, Zürich
Kantonale Ethikkommission Zürich 08.04.2022
2022-00628 CANNABIS PILOT TRIAL IN THE CANTON OF BASEL-LANDSCHAFT IN ACCORDANCE WITH THE ORDINANCE ON PILOT TRIALS UNDER THE NARCOTICS LAW (BETMPV) non clinical, involving persons monocentric A Prof. Dr. Michael Schaub Schweizer Institut für Sucht- und Gesundheitsforschung ISGF Schweizer Institut für Sucht- und Gesundheitsforschung ISGF, Zürich
Ethikkommission Nordwest- und Zentralschweiz EKNZ 30.05.2022
2022-00621 MK-1088-002: A Phase 1/Phase 2 Study to Evaluate the Safety and Tolerability of MK-1088 as Monotherapy and in Combination with Pembrolizumab in Participants with Advanced Solid Tumors clinical trial drugs phase 1/2 multicentric C PD Dr. med. Anastasios Stathis Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona
Kantonsspital St. Gallen, St. Gallen
Kantonsspital Graubünden, Chur
Comitato etico cantonale Ticino Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich 28.06.2022
2022-00618 Automatische und patientenspezifische 3D-MRT-Modelle von Hüftknochen, Hüftknorpel und Labrum für verbesserte chirurgische Entscheidungsfindung personal data/biological material monocentric PD Dr. med. Simon D. Steppacher Inselspital Bern Department für Orthopädie und Traumatologie, Inselspital Bern, Bern
Kantonale Ethikkommission Bern 13.05.2022
2022-00616 Harnessing the beneficial non-specific effects of measles-mumps-rubella vaccine on infection with unrelated pathogens and allergic diseases in children – a single-centre phase IV randomised controlle More ... clinical trial drugs phase 4 monocentric A Dr Laure PITTET University Hospital of Geneva University Hospitals of Geneva, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 19.05.2022 yes
2022-00614 Comparaison du Bioactive Glass avec d’autres substituts osseux : autogreffe, allogreffe et antibiotiques locaux dans le traitement des pseudarthroses et ostéomyélites : une étude rétrospective. personal data/biological material monocentric MD, PD, MERc Sylvain Steinmetz CHUV CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 26.04.2022
2022-00613 A randomized, placebo-controlled, double-blind, monocenter, phase II trial to assess the efficacy of Calcium Dobesilate (CaD) vs. placebo on SARS-CoV-2 viral load amongst outpatients with COVID-19 clinical trial drugs phase 2 monocentric B MD Hervé Spechbach Hôpitaux universitaire de Genève (HUG) Hôpitaux universitaire de Genève (HUG), Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 17.05.2022 yes
2022-00611 Geschlechterspezifische Unterschiede in den Ursachen von Synkopen personal data/biological material monocentric PD Dr. med. Dr. phil. Ksenija Slankamenac Institut für Notfallmedizin Institut für Notfallmedizin, Zürich
Kantonale Ethikkommission Zürich 08.04.2022
2022-00610 Biological behavior of sparsely and densely granulated GH secreting pituitary adenomas: a retrospective observational study of surgical series personal data/biological material monocentric Dr Giulia Cossu CHUV CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 28.04.2022
2022-00609 Comparison Of Accuracy Of Conventional Plating Vs. Intercus Plate In CARD Opening-Wedge Osteotomies Of Distal Radius Malunion personal data/biological material monocentric Prof. Dr. med. Anderas Schweizer Universitätsklinik Balgrist Universitätsklinik Balgrist, Zürich
Kantonale Ethikkommission Zürich 12.04.2022
2022-00606 Personalized IMMUNOtherapy in SEPsis: A multicentre and multinational, double-blind, double-dummy randomized clinical trial clinical trial drugs phase 2 monocentric C Prof. Thierry Calandra Hellenic Institute for the Study of Sepsis CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 01.06.2022
2022-00604 Controllability and the interoception of breathing” (CITRO) non clinical, involving persons monocentric A Dr. Sandra Iglesias, PhD UZH & ETHZ, Institut für Biomedizinische Technik, Translational Neuromodeling Unit Translational Neuromodeling Unit, Zurich
Kantonale Ethikkommission Zürich 06.05.2022
2022-00603 SASCIA - Phase III postneoadjuvant study evaluating Sacituzumab Govitecan, an Antibody Drug Conjugate in primary HER2-negative breast cancer patients with high relapse risk after standard neoadjuvant More ... clinical trial drugs phase 3 multicentric C Dr. med. Ursina Zürrer GBG (German Breast Group) Kantonsspital Winterthur, Winterthur
Brustzentrum, University Hospital Basel, Basel
Kantonsspital St. Gallen, St. Gallen
Brustzentrum Zürich, Zürich
Kantonsspital Graubünden, Chur
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich 24.06.2022
2022-00602 A brief report of an interesting bone marrow finding in systemic mastocytosis personal data/biological material monocentric Dr Vasiliki Papadopoulou CHUV CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 07.04.2022
2022-00595 Streptococcus bovis bacteraemia : metastatic malignancies in the gut are also a gateway personal data/biological material monocentric Sylvain Meylan CHUV CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 19.04.2022
2022-00593 Evaluation of interactions between conventional and complementary medicine in healthcare circuits in Switzerland: a pilot observational study using health insurance billing data. personal data/biological material monocentric Prof / Idris / Guessous Hopitaux Universitaires de Genève Hôpitaux Universitaires de Genève, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 10.05.2022
2022-00592 Visual Symptoms in Postural Tachycardia Syndrome non clinical, involving persons monocentric A Prof. Dr. med. Werner Z`Graggen Universitätsklinik für Neurochirurgie und Neurologie Universitätsklinik für Neurochirurgie und Neurologie, Bern
Kantonale Ethikkommission Bern 24.06.2022
2022-00589 Non-destructive assessment of articular cartilage: Can the device Arthro-BST be used safely and reliably under sterile conditions in hip and knee arthroplasty? non clinical, involving persons monocentric A Prof. Dr. med Moritz Tannast HFR Fribourg - Cantonal Hospital HFR Fribourg - Cantonal Hospital, Fribourg
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 27.04.2022
2022-00588 Smartphone app-assisted discontinuation of PPI – an interprofessional pilot study non clinical, involving persons monocentric A PD DR Isabelle Arnet University of Basel University of Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 10.06.2022