| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-00684 |
AnPHy-ReD Anakinra for the treatment of reccurent Post-prandial Hypoglycemia after total gastrectomy in a patient with end stage Renal Disease |
clinical trial | drugs | phase 2 | monocentric | B | Dr. Matthias Hepprich | Kantonspital Baden |
Cantonal Hospital Olten, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.09.2025 | ||||
| 2025-00679 | Caractérisation rétrospective de la tension artérielle chez les patients adultes atteints de synucléinopathies (PD, MSA ou LBD) | personal data/biological material | monocentric | Dr Bally Julien | CHUV - Neurologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.06.2025 | |||||||
| 2025-00678 | Sodium Management Tool in Hemodialysis Patients | clinical trial | other clinical trials | monocentric | A | Sharon Maloney | LUKS Luzern Department of Internal Medicine |
LUKS, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.09.2025 | |||||
| 2025-00677 | Outcome of Metatarsale Fractures II-IV | personal data/biological material | monocentric | Dr. med. Verena Maria-Anna Hecht | Bürgerspital Solothurn |
Bürgerspital Solothurn, Solothurn |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.04.2025 | |||||||
| 2025-00676 | P-DESIRE (Posterior DEcentering Shoulder Index Recognition Engine) | personal data/biological material | monocentric | Prof. Dr. med. Karl Wieser | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, 8008 Zürich |
Kantonale Ethikkommission Zürich | 17.10.2025 | |||||||
| 2025-00674 |
The AGE RESIST pilot study: Understanding aging and resilience through sweat |
non clinical, involving persons | monocentric | A | Dr. med. Noé Brasier | ETH Zurich |
ETH Zurich, Zurich |
Ethikkommission Ostschweiz (EKOS) | 04.08.2025 | ||||||
| 2025-00673 | In-vivo investigation of inflammatory, neoplastic, and adnexal diseases using non-invasive line field confocal optical coherence tomography | non clinical, involving persons | monocentric | A | Dr. med. Fabienne Fröhlich |
University Hospital of Zurich, Department of Dermatology, Zürich |
Kantonale Ethikkommission Zürich | 01.07.2025 | |||||||
| 2025-00671 | RASolve 301: Phase 3 Multicenter, Open Label, Randomized Study of RMC-6236 versus Docetaxel in Patients with Previously Treated Locally Advanced or Metastatic RAS[MUT] NSCLC | clinical trial | drugs | phase 3 | multicentric | C | Prof. Alessandra Curioni-Fontecedro | Revolution Medicines Inc. |
HFR Fribourg – Kantonsspital, Fribourg Universitaetsspital Basel, Basel Zentrum für Onkologie/Hämatologie Kantonsspital Baden AG, Baden Kantonsspital St. Gallen, St. Gallen |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS) | 16.09.2025 | |||
| 2025-00669 | (Masterarbeit) ECG Analysis of signals from wearables recorded during sports: A pilot study | non clinical, involving persons | monocentric | A | Prof. Dr. sc. ETH., Dr. med. Reto Wildhaber | Fachhochschule Nordwestschweiz |
Fachhochschule Nordwestschweiz, Muttenz |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.05.2025 | Study has ended | |||||
| 2025-00668 | Does anesthesia technique impact on the long-term outcome 5 and 10 years after the first intervention in primary breast cancer surgery? A follow-up analysis. | personal data/biological material | monocentric | Prof. Dr. med Martin Schläpfer | UZH |
University Hospital Zurich, Institute of Anesthesiology and Perioperative Medicine, Zurich |
Kantonale Ethikkommission Zürich | 11.07.2025 | |||||||
| 2025-00665 | Prospective randomized study on the necessity of postoperative stenting after ureteroscopy (URS) for ureteral stones. | clinical trial | other clinical trials | monocentric | A | PD Dr. med. Lukas John Hefermehl |
Division of Urology, Kantonsspital Baden AG, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.08.2025 | ||||||
| 2025-00664 | Investigating lipid dysregulation and alpha-synuclein pathology in Parkinson's Disease using patient-derived Induced Pluripotent Stem Cells | personal data/biological material | monocentric | Dr Anne-Laure Mahul-Mellier | EPFL SV IBI-SV UPDANGELO |
EPFL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.04.2025 | |||||||
| 2025-00663 | Photodynamische Therapie in der Behandlung von Chorioretinopathia centralis serosa – eine retrospektive Studie | personal data/biological material | monocentric | Prof. Dr. med. Christophe Valmaggia | Augenklinik HOCH Standort KSSG |
Augenklinik HOCH Standort KSSG, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 03.04.2025 | |||||||
| 2025-00662 | VISCERAL HYPERSENSITIVITY, URGENCY AND PERSISTENT SYMPTOMS AFTER MUCOSAL HEALING IN ULCERATIVE COLITIS PATIENTS: A PROSPECTIVE COHORT STUDY IN SWITZERLAND | clinical trial | other clinical trials | multicentric | A | Prof. Dr. med. Luc Biedermann | Department of Gastroenterology and Hepatology, University Hospital of Zurich, University of Zurich |
Department of Gastroenterology and Hepatology, University Hospital of Zurich, University of Zurich, Zurich Clarunis - Universitäres Bauchzentrum, Universitätsspital Basel, Basel Klinik Arlesheim, Ales More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.12.2025 | ||||
| 2025-00660 | THE ROLE OF PARENCHYMAL PRESERVING AND ANATOMICAL LIVER RESECTION IN CASE OF SMALL SOLITARY INTRAHEPATIC CHOLANGIOCARCINOMA IN THE MODERN CHEMOTHERAPY ERA: A MULTICENTER COLLABORATIVE STUDY. | personal data/biological material | monocentric | Dr.med Alessandra Cristaudi | Chirurgia Epato-Bilio-Pancreatica, Mininvasiva e Robotica, Centro Trapianti |
EOC, Lugano |
Comitato etico cantonale Ticino | 16.07.2025 | |||||||
| 2025-00659 | " Impact of donor age on the eligibility for corneal tissue donation and the quality of the tissue retrieved: a retrospective analysis | personal data/biological material | monocentric | Dr Horace MASSA | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 20.10.2025 | |||||||
| 2025-00658 | "From Pathology to Imaging: MRI Detection of Endolymphatic Hydrops and Its Clinical Correlations" | personal data/biological material | monocentric | MD, KD Elisa Ventura | Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale |
Department of Neuroradiology, Neurocenter of Southern Switzerland, Regional Hospital of Lugano, Lugano |
Comitato etico cantonale Ticino | 06.05.2025 | |||||||
| 2025-00657 | A Phase 3, Randomized,Double-Blinded, Double-Dummy Study Evaluating the Efficacy and Safety of Empasiprubart Versus Intravenous Immunoglobulin in Adults With Multifocal Motor Neuropathy | clinical trial | drugs | phase 3 | monocentric | C | Dr. med. Helly Hammer | argenx BV |
Inselspital - Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 16.09.2025 | Study has ended | |||
| 2025-00656 | SMART-TBI: Smartphone derived digital biomarkers for mild and moderate traumatic brain injury | non clinical, involving persons | monocentric | A | MSc Qendresa Parduzi | Department of Neurosurgery |
Clinic for Neurosurgery, Lucerne Cantonal Hospital, Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.05.2025 | ||||||
| 2025-00655 | Combination antibiotic treatment with linezolid for Staphylococcus aureus bacteraemia: a randomised controlled trial | clinical trial | drugs | phase 3 | multicentric | B | PD Dr. Richard Kühl | Universitätsspital Basel |
University Hospital Basel, Basel Inselspital Bern, Bern St. Claraspital, Basel Kantonsspital Aarau, Aarau Hôpital du Jura, Delémont Hôpitaux Universitaires de Genève (HUG), Genève HOCH Health Ostschwe More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 18.08.2025 | |||