BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
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2023-D0119 | A randomized, open-label, multicentric, two-arm pivotal trial of SonoCloud-9 combined with carboplatin (CBDCA) vs standard of care lomustine (CCNU) or temozolomide (TMZ) in patients undergoing planned More ... | clinical trial | combination drugs/devices | multicentric | C2 | Adjunct Professor Andreas Felix Hottinger | CARTHERA |
Centre Hospitalier Universitaire Vaudois (CHUV), Department of Clinical Neurosciences, Lausanne Department of Neurosurgery, Bern |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern | 04.07.2024 | ||||
2023-D0118 | Effect of implant surface material and topography on bone regeneration: A two-centre, parallel-group, pilot study | clinical trial | medical devices | monocentric | A1 | Dr. med. dent. Anina Zürcher | Queen Mary University of London (QMUL) |
Clinic of Reconstructive Dentistry, Centre of Dental Medicine, University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 05.03.2024 | |||||
2023-D0117 | Brain circuitry therapeutics for schizophrenia – A randomized controlled clinical study to treat negative symptoms of schizophrenia using non-invasive stimulation of the cerebellum | clinical trial | medical devices | monocentric | C1 | Prof. Indrit Bègue | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 15.05.2024 | |||||
2023-D0116 | Protocol-optimization in computed tomography for the quantification of bone mineral density (BMD) | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Hatem Alkadhi | Diagnostic and Interventional Radiology University Hospital Zurich |
Diagnostic and Interventional Radiology University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 23.01.2024 | |||||
2023-D0113 | PEERLESS II - Randomized Controlled Trial of FlowTriever vs. Anticoagulation alone in Pulmonary Embolism | clinical trial | medical devices | multicentric | A1 | Dr. Gregor Leibundgut | Inari Medical Europe GmbH |
Universitätsspital Basel, Basel Inselspital Bern, Bern Luzerner Kantonsspital, Spitalstrasse |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.01.2024 | ||||
2023-D0112 | Internet-Based Treatment for Depression: A Randomized Trial Comparing Therapist Support and Peer-Support Using an Online Forum. | clinical trial | medical devices | monocentric | A1 | Prof. Dr. Chantal Martin-Soelch | University of Fribourg |
University of Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.05.2024 | |||||
2023-D0111 | A novel endoscopic attachment cap for benign esophageal stricture dilation in children: a randomized, multicentric pilot study. | clinical trial | medical devices | multicentric | A1 | Dr. med. Vasiliki Spyropoulou | University Children’s Hospital Zurich |
University Children’s Hospital, Zurich Universitäts-Kinderspital beider Basel, Spitalstrasse 33, 4056 Basel, Switzerland |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.03.2024 | yes | |||
2023-D0110 | Brain aging – a comparative study in healthy and patients with Multiple Sclerosis as model of a chronic neuroinflammatory disorder | clinical trial | medical devices | monocentric | C2 | PD Dr. med Robert Hoepner | Inselgruppe AG |
Inselgruppe AG, Bern |
Kantonale Ethikkommission Bern | 07.03.2024 | |||||
2023-D0109 | Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect (ASCENT ASD Study) | clinical trial | medical devices | multicentric | C2 | Prof Dr med Oliver Kretschmar | atHeart Medical LLC |
KISPI, Zurich CHUV, Rue de Bugnon 21 |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.05.2024 | yes | |||
2023-D0108 | PREPICare: Assessment of an Innovative Air Mattress on Critically Ill Infants | clinical trial | medical devices | monocentric | C2 | Prof. Dr. med. Barbara Brotschi Audenblatten | Empa |
Universitätskinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 19.03.2024 | yes | Study has ended | |||
2023-D0107 | A Non-Randomized, Prospective or Retrospective, Open-Label, Multi-Center, Observational Clinical Study with Two Arms to Further Evaluate Safety and Performance of the NEXUS® Aortic Arch Stent Graft Sy More ... | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Mario Lachat | Endospan ltd |
Hirslanden Klinik, Zürich |
Kantonale Ethikkommission Zürich | 12.12.2023 | |||||
2023-D0106 | Exploratory study of NeuroLF, an investigational medical device without CE-marking for PET imaging of the human brain | clinical trial | medical devices | monocentric | C2 | Prof. Dr. Martin Hüllner | Positrigo AG |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 14.05.2024 | |||||
2023-D0105 | A mobile application as supportive treatment of endometriosis: the effect on quality of life and endometriosis-associated pain. A randomized controlled trial. | clinical trial | medical devices | monocentric | A1 | Dr. med. Marietta Gulz | University Hospital of Obstetrics and Gynaecology |
University Hospital of Bern Department of Gynecology and Obstetrics, Bern |
Kantonale Ethikkommission Bern | 20.12.2023 | |||||
2023-D0103 | Safety and performance of the Biphasic Plate Distal Femur: A multicenter case series | clinical trial | medical devices | multicentric | A1 | Dr.Med Christian Michelitsch | 41medical AG |
Kantonsspital Graubunden, Chur University Hospital Basel, Department of Orthopaedics and Traumatology Unive Universitätsspital Zürich, Rämistrasse 100 |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.01.2024 | ||||
2023-D0102 | Brain Controlled Spinal Cord Stimulation in Participants with Spinal Cord Injury for Lower Limb Rehabilitation | clinical trial | medical devices | monocentric | C2 | Prof. Dr. Jocelyne Bloch | EPFL SV BMI UPCOURTINE |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.03.2024 | |||||
2023-D0101 | A multicentric, prospective clinical investigation to evaluate microwave imaging via MammoWave® in a population-based screening program for early breast cancer detection to make breast cancer screeni More ... | clinical trial | medical devices | monocentric | C2 | Prof. Thomas Frauenfelder | Umbria Bioenergeenering Technologies (UBT) srl |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 07.06.2024 | |||||
2023-D0100 | Overnight Treatment of Parkinson's Disease Using Vestibular Stimulation from a Rocking Bed (Somnomat Casa) – A Feasibility Study | clinical trial | medical devices | monocentric | C2 | Dr. med. Lenard Lachenmayer | Inselspital, Universitätsspital Bern |
Inselspital, University Hospital, Bern |
Kantonale Ethikkommission Bern | 11.01.2024 | |||||
2023-D0097 |
CAMBRIA-2 (ClinO-MD) A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next-Generation, Oral Selective Estrogen Receptor Degrader) Versus Standar More ... |
clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C2 | Dr. med. Ursina Zürrer-Härdi | AstraZeneca AB |
Kantonsspital Winterthur, Klinik für Medizinische Onkologie und Hämatologie, Winterthur Kantonsspital Baden, Im Ergel Hirslandenklinik St. Anna, Zentrum für Onkologie St. Anna-Strasse 32 Universitäts More ... |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, More ... | 28.03.2024 | ||||
2023-D0096 |
BIO|MASTER.Amvia Post Market Clinical Follow-up Study for the Amvia/Solvia Pacemaker Family |
clinical trial | medical devices | monocentric | A1 | Dr. Christian Grebmer | BIOTRONIK SE & Co. KG |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.11.2023 | |||||
2023-D0094 | A Single-Arm Pilot Study to Evaluate the Safety of Adipearl Injection in the Subcutanaeous Tissues of Adults | clinical trial | medical devices | monocentric | C2 | Dr. Johann Wary | Volumina Medical S.A. |
Summit Clinic, Crans-Montana |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 19.01.2024 | |||||