| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-00627 | The Spinal Balance Score - A novel linear and unidimensional patient-reported outcome measure for adult spinal deformity | non clinical, involving persons | monocentric | A | Pr Dominique Rothenfluh | Bureau du promoteur de recherche |
Centre hospitalier universitaire vaudois - CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.06.2025 | ||||||
| 2025-00626 | PARAVITAL, a machine learning model for predicting intraoperative ICG angiography perfusion of parathyroid glands | non clinical, involving persons | monocentric | A | Dr Marco Stefano Demarchi | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaire de Genève, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.07.2025 | ||||||
| 2025-00625 | A Global, Randomized, Open-label, Multicenter Phase 3 Trial Evaluating BJT-778 vs Bulevirtide for the Treatment of Chronic Hepatitis Delta Infection (AZURE-2) | clinical trial | drugs | phase 3 | multicentric | C | Prof. Andreas Kremer | Mirum Pharmaceuticals, Inc. |
Klinik für Gastroenterologie und Hepatologie, Universitätsklinik Zürich, Zürich Gastro-entérologie et Hépatologie, Hopital Universitaire Genève, Genève Kantonsspital St. Gallen, Gastroenterology and H More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Commission Cantonale d'éthique de la recherche Genève (CCER) | 28.11.2025 | |||
| 2025-00624 | How developing a transitional clinic to support individuals released from prison: a qualitative exploration of their needs and expectations | non clinical, involving persons | monocentric | A | Elodie Lucien-Schmutz | Unisanté |
Unisanté, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 01.07.2025 | ||||||
| 2025-00623 | ICU Background Early Awareness for Critical deterioratiON (BEACON) | non clinical, involving persons | monocentric | A | Dr. med. Martin Faltys | ETH Zürich |
Insel Gruppe AG, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 02.06.2025 | ||||||
| 2025-00622 | Short-term low-dose low-molecular-weight heparin to prevent postpartum thrombosis: a pragmatic, multi-center, open-label randomized controlled study | clinical trial | drugs | phase 3 | multicentric | A | Dr. Marc Blondon | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Geneva Lindenhofspital, Bern USB, Basel KSB, Baden Luzerner Kantonsspital, Luzern Kantonsspital Aarau, Aarau EOC, Lugano CHUV, Lausanne HFR, Fribourg RHNe, Neuchâtel More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cantonale Ticino | 05.08.2025 | |||
| 2025-00620 | Hesav Healthy Campus - Investigating physical activity levels and mental well-being in a school of health sciences | non clinical, involving persons | monocentric | A | Dr Jennifer Masset | HESAV - HES-SO |
HESAV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.06.2025 | ||||||
| 2025-00619 | Decoding Preterm Birth Outcomes: Genetic and Biomarker Predictors for Tailored Interventions | non clinical, involving persons | monocentric | A | Prof. Dr. med Nicole Ochsenbein-Kölble | University Hospital Zurich |
University Hospital Zurich, Department of Obstetrics, Zurich |
Kantonale Ethikkommission Zürich | 19.08.2025 | ||||||
| 2025-00617 | Investigation of risk factors and biomarkers associated with knee arthrofibrosis (stiffness) occurring after anterior cruciate ligament (ACL) reconstruction | non clinical, involving persons | monocentric | A | Dr. Philippe Tscholl | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.12.2025 | ||||||
| 2025-00616 | Long-term outcomes of a cohort of patients with TCF3::HLF positive acute lymphoblastic leukemia treated with CD19-directed CAR-T cell Therapy | personal data/biological material | monocentric | Prof. Dr. med. Dr. sc. nat. Jean-Pierre Bourquin | University Children's Hospital Zurich - Eleonore Foundation |
University Children's Hospital Zurich - Eleonore Foundation, Zürich |
Kantonale Ethikkommission Zürich | 12.12.2025 | |||||||
| 2025-00614 | Can pulse pressure assessment at the bedside detect low values or track changes of stroke volume in critically ill patients? The multicenter, cross-sectional, observational, ANDROMEDA-PEGASUS Study. | personal data/biological material | multicentric | Prof. Dr. med. Sascha David | Pontificia Universidad Católica de Chile |
University Hospital Zurich, Zurich Kantonsspital Luzern, Luzern Kantonsspital Winterthur, Winterthur Spital Uster, Uster |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 18.07.2025 | ||||||
| 2025-00613 | Investigation of gene regulatory mechanisms in immune-related diseases | personal data/biological material | monocentric | Prof. Dr. Zaugg, Judith | Basel University Hospital |
Basel Universität, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.03.2025 | |||||||
| 2025-00612 | Unravelling brain alterations and associated neurodevelopmental sequelae in children born with complex medical conditions: A secondary analysis of existing datasets | personal data/biological material | monocentric | Melanie Ehrler | Universitaets-Kinderspital Zürich |
Dr. sc. med. Melanie Ehrler Research Fellow Child Development Center, University Children’s Hospital Zurich, Zürich |
Kantonale Ethikkommission Zürich | 24.10.2025 | |||||||
| 2025-00611 | Investigating the accuracy of breast density self-assessment and the effect of examination conditions on perceived distress in breast cancer screening-settings: Implications for clinical practice | non clinical, involving persons | monocentric | A | Prof. Dr. med. Thomas Frauenfelder | Universitätsspital Zurich, Diagnostic and Interventional Radiology University Hospital Zurich |
Diagnostic and Interventional Radiology Universitätsspital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 24.10.2025 | ||||||
| 2025-00610 | A Phase 1b/2a Study to Assess the Safety and Efficacy of OPM-101 Combined with Anti-PD-1 in Patients with Advanced Melanoma Showing Resistance to Anti-PD-1 | clinical trial | drugs | phase 1/2 | multicentric | C | Ben Aissa Assma (MD,PhD) | Oncodesign Precision Medicine |
Hopitaux Universitaires Geneve, Geneve Inselspital, Universitätsspital Bern, Bern Universtätsspital Zürich, Zürich |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 03.09.2025 | |||
| 2025-00608 | SURFSUBQ – A PROSPECTIVE LONGITUDINAL MULTICENTER OBSERVATIONAL STUDY TO INVESTIGATE NEUROFILAMENT LIGHT CHAIN LEVELS AND PATIENT SATISFACTION AFTER SUBCUTANEOUS OCRELIZUMAB ADMINISTRATION IN PERSONS More ... | non clinical, involving persons | multicentric | A | PD Dr. med. Robert Hoepner | Roche Pharma (Schweiz) AG |
Inselspital, Universitätsspital Bern, Bern Bellevue Medical Group, Zürich |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 13.05.2025 | |||||
| 2025-00607 | Targeting Autophagy in Depression: Caloric Restriction, Exercise and Dietary Interventions. | non clinical, involving persons | monocentric | A | Dr. med. Dr. rer. nat. Jens Stepan | University Hospital Zurich |
Division of Reproductive Endocrinology, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 12.09.2025 | ||||||
| 2025-00606 | Evaluation of the safety and effectiveness of open reduction and internal fixation of distal radius fractures | personal data/biological material | monocentric | Prof. Dr. med. Andreas Marc Müller | Universitätsspital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.04.2025 | |||||||
| 2025-00605 | Evaluierung der objektiven und subjektiven Bestimmung der Akkommodationsbreite bei Personen ohne und mit Akkommodationsinsuffizienz | non clinical, involving persons | monocentric | A | Joëlle Joss | Fachhochschule Nordwestschweiz FHNW Hochschule für Technik und Umwelt |
Fachhochschule Nordwestschweiz Hochschule für Technik und Umwelt, Olten |
Ethikkommission Ostschweiz (EKOS) | 03.04.2025 | ||||||
| 2025-00604 | Retinal vessel flicker light responsiveness and its relation to analysis protocols, static and metabolic data in healthy subjects | personal data/biological material | monocentric | Prof. Dr. Margarita Todorova | Cantonal Hospital St. Gallen Department of Ophthalmology |
HOCH Health Ostschweiz, Eye clinic, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 03.04.2025 | |||||||