| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-00603 | Mechanisms of myocardial injury and ischemia in patients with rapid Atrial Fibrillation | non clinical, involving persons | multicentric | B | PD Dr Jasper Boeddinghaus | The University of Edinburgh and Lothian Health Board ACCORD |
University Hospital Basel, Basel Cantonal Hospital Lucerne, Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.05.2025 | |||||
| 2025-00602 | Patient-Reported Outcomes Following Total Knee Arthroplasty | personal data/biological material | monocentric | Prof. Dr. med. Sandro Fucentese | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 27.05.2025 | |||||||
| 2025-00600 | Exploration of Novel MRI Sequences in Clinical Practice – A Pilot Study | non clinical, involving persons | monocentric | A | PD Dr. med. Maurice Pradella | Universitätsspital Basel, Radiologie |
Universitätsspital Basel / Radiologie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.09.2025 | ||||||
| 2025-00599 | Analysis of Extracellular Vesicles Involved in Breast Cancer | non clinical, involving persons | monocentric | A | Prof. Gerrit Borchard | University of Geneva |
University of Geneva, Section of Pharmaceutical Sciences, Biopharmaceutical Sciences, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 12.01.2026 | ||||||
| 2025-00598 | Long-Term Stability of Orthodontic Treatments for Class II Malocclusions | personal data/biological material | monocentric | Professor Gregory Antonarakis | Department of Orthodontics |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 15.07.2025 | |||||||
| 2025-00597 |
Invasive fungal infections in pediatric oncology: a retrospective single-center analysis |
personal data/biological material | monocentric | PD Dr. med. Alexandra Schifferli | Universitäts-Kinderspital beider Basel (UKBB) |
Universitäts-Kinderspital beider Basel (UKBB), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.04.2025 | |||||||
| 2025-00596 | Prevalence and management of chronic hepatitis B, C, and D during pregnancy: a retrospective study | personal data/biological material | monocentric | Dr Montserrat Fraga | CHUV - Gastro-entérologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.08.2025 | |||||||
| 2025-00595 | Circadian Rhythms and Sleep in Simulated Space: Understanding Adaptations for Space Exploration | non clinical, involving persons | monocentric | A | Ms Maria Comas Soberats | Sleep unit at the Araba university hospital |
sleep unit at the Araba university hospital, Vitoria-Gasteiz |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.06.2025 | Study has ended | |||||
| 2025-00594 | Chromatin imaging atlas of blood cells during healthy aging | personal data/biological material | monocentric | Prof. Dr. G.V. Shivashankar | Paul Scherrer Institut |
Paul Scherrer Institut, Villigen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.07.2025 | |||||||
| 2025-00593 | Risk profile and projectors of outcome of ischemia related bowel perforation due to non-occlusive mesenteric ischemia (NOMI) in ICU patients (ROMERO) | personal data/biological material | monocentric | Sascha David | University Hospital Zurich |
Institute of Intensive Care Medicine, University Hospital Zurich, 8091 |
Kantonale Ethikkommission Zürich | 24.06.2025 | |||||||
| 2025-00592 |
Does the Co-administration of Dexmedetomidine Improve Hemodynamic Stability During Carotid Endarterectomy (CEA) under General Anaesthesia? A Single-Centre Prospective Randomized Contro More ... |
clinical trial | drugs | n/a | monocentric | A | Christian Vetter, Dr. med. |
Klinik für Anästhesiologie und Schmerzmedizin, Inselspital Bern Freiburgstrasse, Bern |
Kantonale Ethikkommission Bern | 05.05.2025 | |||||
| 2025-00591 | Outcome of surgical spinal cord untethering in lipomyelomeningocele and filum lipoma | personal data/biological material | monocentric | Prof. Dr. Raphael Guzman |
Neurosurgery and Pediatric Neurosurgery, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.05.2025 | ||||||||
| 2025-00590 |
A European, multicenter, prospective observational phase IV clinical study to assess the impact of lebrikizumab on health related well-being and control of skin manifestations in patients with moder More ... |
non clinical, involving persons | multicentric | A | Prof.Dr.med. Charlotte Brüggen | Almirall S.A |
Universitätsspital Zürich (USZ), Zürich Dermatology & Skin Care Clinic, Buochs La clinique Quai du Seujet 14, Genève Clinique Cours de Rive 2, Cours de Rive 2 Kantonspital St. Gallen (KSSG), St. Galle More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 08.08.2025 | |||||
| 2025-00589 | Réponses cardiorespiratoires et vasculaires lors d’une tâche de pédalage quadrupédique : une étude pilote | non clinical, involving persons | monocentric | A | Dr. Jérôme Barral | UNIL - SSP (ISSULssp) |
University of Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 12.05.2025 | ||||||
| 2025-00588 | Retrospective Database for the Investigation and identification of possible risk factors for recur-rences in chronic subdural hematomas | personal data/biological material | monocentric | Prof. Dr. Jehuda Soleman | Neurochirurgie Basel |
Neurochirurgie Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.04.2025 | Study has ended | ||||||
| 2025-00587 | Untersuchung des aktuellen Versorgungsstandards bei histopathologisch gesichertem Endometriumkarzinom – eine retrospektive, multizentrische JAGO-NOGGO-Analyse | personal data/biological material | monocentric | Dr. med. Franziska Geissler | Junge Akademie Gynäkologische Onkologie |
Frauenklinik Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.03.2025 | |||||||
| 2025-00586 | A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab Monotherapy for the First-line Treatment of Patients with PD-L1-high Metastatic Non-small Cell Lung C More ... | clinical trial | drugs | phase 3 | monocentric | C | Karim Abdelhamid | AstraZeneca AB |
University Hospital of Lausanne (CHUV), Medical Oncology, Oncology Department, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.08.2025 | ||||
| 2025-00584 | Effect of Phosphoric Acid Etching Duration on the Performance of Direct Resin-Based Composite Restorations in Permanent Anterior Teeth: A Randomized Controlled Single-Center Trial | clinical trial | other clinical trials | monocentric | A | PD Dr. med. dent. Florin Eggmann | University of Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.04.2025 | |||||
| 2025-00582 | A Proof-of-Concept Study to Evaluate the precision of ABL-101 Perfluorocarbon and Fluorine-19 Magnetic Resonance Imaging in Mapping of Atherosclerotic Plaque Composition and Inflammation in Patients U More ... | clinical trial | drugs | phase 2 | monocentric | C | Professor Dr MD Patrik Michel | CHUV - Radiodiagnostic et |
Deputy Head of the Stroke Center, Neurology Service, Department of Clinical Neurosciences, CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.07.2025 | ||||
| 2025-00579 | VeMic: Association of microcirculation, Vexus score and femoral vein doppler in patients on the ICU after non-emergency cardiac surgery | non clinical, involving persons | monocentric | A | Dr. med. Gregor Loosen | University Hospital Basel |
University Hospital Basel, Intensive Care Unit, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.06.2025 | ||||||