| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2016-00066 |
(20120123) Double-blind, Randomized, Multicenter, Placebo-controlled, Parallel Group Study to Characterize the Efficacy, Safety, and Tolerability of 24 Weeks of Evolocumab for Low Density Lipoprotei More ... |
clinical trial | drugs | phase 3 | multicentric | B | Prof. André Miserez | AMGEN Inc. |
Diagene Incorporated, 4153 Reinach Hopitaux Universitaires de Geneve, Genève |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission Cantonale d'éthique de la recherche Genève (CCER) | 25.05.2016 | yes | Study has ended | |
| 2016-00065 | SaltoTM and Salto TalarisTM Total Ankle Replacement: Prospective Study of 302 Patients with a 1 to 14 year Follow-Up | personal data/biological material | multicentric | MD Antoine ACKER | Centre ASSAL |
Centre ASSAL, Geneva CHUV, Lausanne |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 29.03.2016 | ||||||
| 2016-00064 | Breast cancer diagnosis and characterization with current breast imaging methods: a retrospective evaluation. | personal data/biological material | monocentric | PD Dr. med. Dr. sc. hum. Andreas Boss | Institut für Interventionelle und diagnostische Radiologie USZ |
Institute of Diagnostic and Interventional Radiology, Zürich |
Kantonale Ethikkommission Zürich | 16.03.2016 | |||||||
| 2016-00063 | IS THERE LESS DISLOCATION RATE FOLLOWING DIRECT ANTERIOR APPROACH FOR TOTAL HIP ARTHROPLASTY ? | personal data/biological material | monocentric | Christophe Tissot |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 15.02.2016 | ||||||||
| 2016-00062 | L’arresto cardiaco (AC) come trauma per il familiare: sintomatologia e possibili modelli di indagine, intervento e prevenzione | non clinical, involving persons | monocentric | A | Prof. Claudio Benvenuti | Università degli Studi di Bergamo |
Fondazione Cuore Ticino, Breganzona |
Comitato etico cantonale Ticino | 21.07.2016 | ||||||
| 2016-00061 |
MK-3475-177: A Phase III Study of Pembrolizumab (MK-3475) vs. Chemotherapy in Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (KEYNOTE-177) |
clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Dieter Koeberle | Merck Sharp & Dohme LLC, Global Clinical Trial Operations Switzerland |
St. Claraspital, Medizinische Onkologie, Basel Hôpitaux Universitaires de Genève (HUG), Département d’Oncologie, Genf Kantonsspital St. Gallen, Klinik für Onkologie und Hämatologie, St. Gallen Univers More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 28.04.2016 | Study has ended | ||
| 2016-00060 | Dynamic Networks of Perception, Cognition and Action | non clinical, involving persons | monocentric | A | Ph.D, Gijs PLOMP | University of Fribourg |
University of Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.03.2016 | ||||||
| 2016-00059 | Prävalenz einer Thrombozytopenie und Korrelation zum Schweregrad der sekundären Erythrozytose bei Erwachsenen mit angeborenen zyanotischen Herzfehlern. | personal data/biological material | monocentric | DP Dr. med. Matthias Greutmann |
Klinik für Kardiologie, UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 21.04.2016 | ||||||||
| 2016-00058 | The Medtronic CoreValve™ Evolut R™ FORWARD Study | non clinical, involving persons | multicentric | A | Prof. Dr. med. Francesco Maisano | Medtronic (Schweiz) AG |
UniversitätsSpital Zürich, Zürich Inselspital Bern, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 17.11.2016 | |||||
| 2016-00057 | Gesundheitseffekte verschiedener städtischer Erholungsorte | non clinical, involving persons | monocentric | A | Dr. Nicole Bauer | Eidg. Forschungsanstalt WSL |
WSL, Birmensdorf |
Kantonale Ethikkommission Zürich | 26.04.2016 | Study has ended | |||||
| 2016-00056 |
Epidemiology of critical events, morbidity and mortality in neonatal anaesthesia: A European prospective multicentre observational study |
non clinical, involving persons | multicentric | A | Prof Walid Habre | European Society of Anaesthesiology |
Geneva University Hospitals, Geneva SL Kinderanästhesie Universitätsklinik für Anästhesiologie und Schmerztherapie Inselspital, Bern University Children's Hospital Basel , Basel Kantonsspital Luzern, More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... | 31.03.2016 | yes | Study has ended | |||
| 2016-00054 | Comparison of perineal ultrasound in men before and after radical prostatectomy and in incontinent men after radical prostatectomy before and after operative treatment with male sling and comparison w More ... | clinical trial | medical devices | monocentric | A | Prof. Dr. med. Hubert John | Klinik für Urologie |
Klinik für Urologie, Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 15.09.2016 | |||||
| 2016-00053 |
A Phase 3, Placebo-Controlled, Randomized, Double-Blind, Multi- Center Study of LJPC-501 in Patients with Catecholamine-Resistant Hypotension (CRH) |
clinical trial | drugs | phase 3 | monocentric | C | Dr Matthias Haenggi | La Jolla Pharmaceutical Company Inc. |
Bern University Hospital - Inselspital, Bern |
Kantonale Ethikkommission Bern | 06.04.2016 | Study has ended | |||
| 2016-00052 | A Randomized, Open-label Study of Ponatinib Versus Nilotinib in Patients with Chronic Myeloid Leukemia in Chronic Phase Following Resistance to Imatinib | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. Dr. Stefan Balabanov | ARIAD Pharmaceuticals, Inc. |
Universitätsspital Zürich, Klinik für Hämatologie, 8091 Zürich |
Kantonale Ethikkommission Zürich | 04.08.2016 | Study has ended | |||
| 2016-00051 | A Swiss Paediatric Oncology Group (SPOG) initiated multi-center open-label randomized controlled multiple crossover non-inferiority trial on safety of a high versus low temperature limit defining feve More ... | clinical trial | other clinical trials | multicentric | B | Prof. Dr. med Roland Ammann | Swiss Paediatric Oncology Group SPOG |
Kinderklinik Inselspital, 3010 Bern Universitäts-Kinderspital beider Basel UKBB, Hämatologie/Onkologie, Basel Kantonsspital Luzern, Kinderspital, Pädiatrische Hämatologie/Onkologie, Luzern Hôpital Uni More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de l More ... | 20.04.2016 | yes | Study has ended | ||
| 2016-00050 | Description, Predictors and Prediction Modeling of cART Medication Adherence and Immuno-virologic outcomes among HIV infected Adults in Lausanne, Switzerland | personal data/biological material | monocentric | Susan Kamal | Policlinique Medicale Universitaire |
Policlinique Medicale Universitaire, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.03.2016 | |||||||
| 2016-00048 | CLXH254X2101 - A phase I dose finding study of oral LXH254 in adult patients with advanced solid tumors harboring MAPK pathway alterations | clinical trial | drugs | phase 1 | monocentric | C | Prof. Dr. med. Reinhard Dummer | Novartis Pharma Schweiz AG |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 31.03.2016 | Study has ended | |||
| 2016-00047 | Testing the allergenicity of vaccinated vs. not vaccinated cats based on an in-vitro basophil activation test (BAT) using blood from cat allergic patients | non clinical, involving persons | monocentric | A | PD Dr. med. Thomas Kündig | Department of Dermatology USZ |
USZ, 8091 Zurich |
Kantonale Ethikkommission Zürich | 10.03.2016 | Study has ended | |||||
| 2016-00046 | Real-time guided stereotactic radiotherapy in lung cancer using endovascular coils for tumor marking : head-to-head comparison between endovascular and bronchoscopic fiducial marker insertion. | clinical trial | other clinical trials | monocentric | B | Dr. Duran Rafael | CHUV |
University Hospital of Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 12.07.2016 | |||||
| 2016-00045 |
Efficacy of non steroidal antiinflammatory eye drops and/or carboanhydrase inhibitor blockers in the treatment of central serous chorioretinopathy (CRCS) |
personal data/biological material | monocentric | Dr. med. Argyrios Chronopoulos | Geneva University Hospitals, Department of Ophthalmology |
Geneva University Clinics, Department of Ophthalmology, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 12.07.2016 | Study has ended | ||||||