| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01698 | The role of IL-6 in regulating amino acid uptake in immune cells | non clinical, involving persons | monocentric | A | Dr. med. Beckey Trinh |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.11.2023 | |||||||
| 2023-01697 | Development of a cGAS "armored" CAR-T cells cancer therapy | personal data/biological material | monocentric | Professor Andrea Ablasser | EPFL-SV-GHI-UPABLASSER |
EPFL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.09.2023 | |||||||
| 2023-01696 |
“Does autoimmune disease following ovarian cancer diagnosis affect prognosis?” «Beeinflusst die Entwicklung einer Autoimmunerkrankung nach Diagnose eines Ovarialkarzinoms das Überleben?» |
personal data/biological material | monocentric | Professor Mathias Fehr |
Spital Thurgau AG (Frauenfeld), Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 14.09.2023 | ||||||||
| 2023-01695 | Toward personalized vaccinology for allogeneic hematopoietic cell transplant recipients | personal data/biological material | monocentric | Dr Irene Abela | Universitätsspital Zürich |
Universätsspital, Zürich |
Kantonale Ethikkommission Zürich | 10.11.2023 | |||||||
| 2023-01693 | MEMENTO – A Phase 3b/4, Randomized, Double-blind, Placebo-controlled Clinical Study to Evaluate Mavacamten in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy to Assess the Impact on My More ... | clinical trial | drugs | phase 4 | multicentric | C | Prof. Dr. / Robert / Manka | Myokardia, Inc. |
University Hospital Zurich, Zurich Hôpitaux Universitaires de Genève, Geneva Cardiocentro Ticino, Lugano |
Kantonale Ethikkommission Zürich | Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino | 01.12.2023 | |||
| 2023-01692 | Development and Validation of a Multivariate Prediction Model for Suspected Ocular Myasthenia Gravis | personal data/biological material | monocentric | PD Dr. med. Konrad Weber | Departments of Neurology and Ophthalmology |
Departments of Neurology and Ophthalmology, Zürich |
Kantonale Ethikkommission Zürich | 20.10.2023 | |||||||
| 2023-01691 | The PODCAST-Question: PostOperative Dilatation / Calibration After Surgical Treatment of Hirschsprung's disease – what is necessary? | personal data/biological material | monocentric | Dr. med. Daniel Keese | Kinderspital Zürich |
Department of Paediatric Surgery University Children's Hospital Zurich, 8032 |
Kantonale Ethikkommission Zürich | 24.11.2023 | |||||||
| 2023-01690 | The SCI NutriTool: short dietary instrument designed to identify individuals with a spinal cord injury who are not adhering to healthy diet recommendations | non clinical, involving persons | monocentric | A | PD Dr M. Glisic | Swiss Paraplegic Research |
Swiss Paraplegic Research, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.12.2023 | ||||||
| 2023-01689 | Functional Soft Palate Reconstruction | personal data/biological material | monocentric | Prof. Dirk Johannes Schaefer | Universitätsspital Basel |
Universitätsspital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.11.2023 | |||||||
| 2023-01688 | Clinical and Molecular Characterization of Patients with Perioperative Anaphylaxis | non clinical, involving persons | monocentric | A | Prof.Dr. Karin Hartmann | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.11.2023 | ||||||
| 2023-01686 | Exploratory research study to investigate molecular mechanisms and biomarkers of dry eye disease in human ocular surface samples | non clinical, involving persons | monocentric | A | Prof. Dr. med. Christoph Tappeiner |
Pallas-Kliniken AG, 4600 Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.11.2023 | |||||||
| 2023-01685 | Feasibility of a brief manualized psychotherapy for traumatized mothers and their young children: Clinician Assisted Videofeedback Exposure Therapy (CAVEAT) | non clinical, involving persons | monocentric | A | Prof Daniel S. Schechter | Centre Hospitalier Universitaire Vaudois (CHUV) |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.03.2024 | yes | |||||
| 2023-01684 | Adherence to enhanced recovery after surgery (ERAS) in an elderly population following colorectal resection | personal data/biological material | monocentric | Marionna Cathomas | Chirurgie, Kantonsspital Baselland |
Kantonsspital Baselland, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.11.2023 | |||||||
| 2023-01683 | The further development of prognostic models to predict the outcome of treatment for spine patients. | personal data/biological material | monocentric | Dr. Fabio Galbusera | Schulthess Clinic |
Schulthess Clinic, Zurich |
Kantonale Ethikkommission Zürich | 08.12.2023 | |||||||
| 2023-01682 | Prospective, Randomized-Controlled Study of the Effect of Propofol vs. Sevoflurane on Erections during Narcosis in Transurethral Surgery | clinical trial | drugs | phase 4 | monocentric | A | Etienne Xavier Keller | University Hospital of Zurich |
University Hospital of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 31.10.2023 | ||||
| 2023-01681 | Artificial Intelligence assisted Ultrasound for Real Time Registration and Detection of Critical Structures in Foot and Ankle Surgery | deceased persons | monocentric | PD Dr. med. Dipl. Phys. Arnd Viehöfer | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 27.10.2023 | |||||||
| 2023-01679 | The influence of pre-existing advanced osteoarthritis in intertrochanteric femur fractures on the quality of life after endomedullary nailing | non clinical, involving persons | monocentric | A | Dr. med. Method Kabelitz | Departmend Surgery |
Surgery, Zuerich |
Kantonale Ethikkommission Zürich | 05.03.2024 | ||||||
| 2023-01678 | TransUrine - Quantity and quality of intracellular RNA obtained from urine samples of critically ill patients: a pilot study. | personal data/biological material | monocentric | Dr Antoine Schneider | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 05.09.2023 | |||||||
| 2023-01677 | Training Cold Showers: A randomized controlled study | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Jens Gaab | University of Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.10.2023 | |||||
| 2023-01675 | Assessment of physician consideration of electronic patient reported outcomes of patients with gout, rheumatoid arthritis, Sjogren’s syndrome or systemic lupus erythematosus on the frequency of therap More ... | non clinical, involving persons | multicentric | A | Prof. Dr. Ulrich Walker | Strasbourg University Hospital (SUH) |
University Hospital, Basel Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.10.2023 | |||||