BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
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2024-D0077 | A multi-center randomized controlled trial first in human study to assess the feasibility and safety of adjunctive treatment with the HemoSystem REBOOT in critically ill patientS wiTh sepsis-induced i More ... | clinical trial | medical devices | multicentric | C2 | Prof. Dr. Jörg Schefold | hemotune AG |
University Hospital Bern, Inselspital, Bern University Hospital Zurich, Institut für Intensivmedizin, Rämistrasse 100 |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 27.09.2024 | ||||
2024-D0068 |
The effectiveness of heat treatment on knee pain in patients with osteoarthritis - an international, multicenter clinical investigation. Prospective, open-label, one-arm, post-market, effectiveness c More ... |
clinical trial | medical devices | multicentric | A2 | Dr. Marco Marano | Angelini Pharma S.p.A., |
Department of Orthopaedics and Traumatology, Ars Medica Clinic, Lugano Centro dello Sport Ars Medica, Via Cantonale 38, Manno Clinica Ars Medica, Via Grumo 16, Gravesano Clinica Ars Medica, Via Grumo More ... |
Comitato etico cantonale Ticino | Comitato etico cantonale Ticino | 23.09.2024 | ||||
2024-D0054 | CLARITY-Gastric01 - A Phase III Multi-center, Open-label, Sponsor-blinded, Randomized Study of AZD0901 Monotherapy Compared with Investigator’s Choice of Therapy in Second- or Later-Line Adult Partici More ... | clinical trial | in vitro diagnostic medical devices | multicentric | C2 | Dr med Alexander Siebenhüner | AstraZeneca |
Klinik für Hämatologie und Onkologie Hirslanden Zürich AG , Witellikerstrasse 40, 8032 Zürich INSELSPITAL Universitätsspital Bern Universitätsklinik für medizinische Onkologie Klinische Forschungseinh More ... |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 27.08.2024 | ||||
2024-D0052 | An interventional, prospective study protocol for testing advanced solid tumor FFPE tissue samples to determine patient eligibility for enrollment into Arms B and C, respectively, of Debiopharm’s Phas More ... | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C2 | Anastasios Stathis | Debiopharm International S.A. |
Istituto Oncologico della Svizzera Italiana - Clinical site, Bellinzona Inselspital, Universitaetsspital Bern-, Bern Kantonsspital St. Gallen, Rorschacher Strasse 95 CH-9007 St. Gallen |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS) | 28.10.2024 | ||||
2024-D0051 | HYsterectomy with adnexal surgery Procedures with the DEXTER Robotic system | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Michael Mueller | Distalmotion SA |
Inselspital Bern, Bern Spitäler fmi AG, Unterseen Kantonsspital Baden, Im Ergel 1 Hirslanden Zurich, Witellikerstrasse 40 |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 31.07.2024 | ||||
2024-D0037 | The DEXTER-assisted non-emergent and acute cholecystectomy Study | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Stefan Breitenstein | Distalmotion SA |
Kantonsspital Winterthur, Winterthur Centre Hospitalier Universitaire Vaudois, Rue du Bugnon 46 Hirslanden Zurich, Chirurgisches Zentrum Zürich Witellikerstrasse 40 |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Zürich | 14.06.2024 | ||||
2024-D0033 | BradycArdia paCemaKer with AV interval modulation for Blood prEssure treAtmenT (BACKBEAT Trial) | clinical trial | medical devices | multicentric | C2 | Dr. Tardu Özkartal | Orchestra Biomed |
Istituto Cardiocentro Ticino, Lugano Universitätsspital Bern, Bern University Hospital Basel, Cardiology Petersgaben 4 |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.10.2024 | ||||
2024-D0018 | A performance evaluation study for the testing of DNA extracted from tumor tissue samples, using the therascreen® KRAS RGQ PCR Kit, from participants with Non-Small Cell Lung Cancer in Lilly’s Clinica More ... | clinical trial | in vitro diagnostic medical devices | multicentric | A2 | Ulrich Richer | Qiagen Manchester Limited |
University Hospital of Zurich, Zürich Cantonal Hospital Winterhur, Brauerstrasse 15, Postfach 834 CH-8401 Winterhur |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 28.06.2024 | ||||
2024-D0011 | BIOTRONIK – Safety and Clinical Performance of the Drug Eluting Resorbable Coronary MAGnesium Scaffold System (Freesolve®) in the Treatment of Subjects with de Novo Lesions in Native Coronary Arteries More ... | clinical trial | medical devices | multicentric | A2 | PD Dr. med. | BIOTRONIK AG |
Juan Fernando, Iglesias Inselspital Bern, Bern University Hospital Basel, University Heart Center Petersgraben 4 Stadtspital Triemli, Klinik für Kardiologie Birmensdorferstrasse 497 Universitätsspit More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.05.2024 | ||||
2024-D0006 | Advancing Cath Lab Results with FFRangio® Coronary Physiology Assessment: The ALL-RISE Study | clinical trial | medical devices | multicentric | A1 | Dr. Juan Fernando Iglesias | CathWorks Inc. |
Unité de Cardiologie interventionnelle Service de Cardiologie Hôpitaux Universaires de Genève, Genève CHUV, Service de cardiologie, Unite de Cardiologie lnter HFR, Chemin de Pensionnats 2-6 |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.06.2024 | ||||
2024-D0002 | Clinical Performance Study Plan for FoundationOne® Liquid CDx as a Clinical Trial Assay in Clinical Trial GO42144 PLAN-00030, Version 04 | clinical trial | in vitro diagnostic medical devices | multicentric | C1 | Dr. med. et phil. nat. Simon Häfliger | Genentech, Inc. |
Inselspital Bern, Universitätsklinik für Medizinische Onkologie, Bern Hôpitaux Universitaires de Genève, Département d'Oncologie, Rue Gabrielle-Perret-Gentil 4 |
Kantonale Ethikkommission Bern | Commission Cantonale d'éthique de la recherche Genève (CCER) | 27.03.2024 | Study has ended | |||
2024-01959 | Serial measurements of C-reactive protein in patients hospitalized for community-acquired pneumonia: is less more? – the SMART-CRP study | personal data/biological material | multicentric | Prof. Dr. med. Carole Elodie Aubert | Bern University Hospital |
Department of General Internal Medicine, Bern University Hospital, Inselspital, Bern Spitalzentrum Biel, Biel |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 30.10.2024 | ||||||
2024-01807 | Catheter ABlation of Atrial fibrillation versus atrioventricular nodal ablation with CondUction System pacing in persistent atrial fibrillation and heart failure | clinical trial | other clinical trials | multicentric | A | Prof Haran Burri | HUG |
HUG, GENEVE Universitätsklinik für Kardiologie, Bern Division of Cardiology Spitalstrasse 40,, Basel University Heart Center, University Hospital Zurich, Zurich |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 16.09.2024 | ||||
2024-01740 | Enroll-HD: A Prospective Registry Study in a Global Huntington's Disease Cohort | non clinical, involving persons | multicentric | A | Prof. Michael Orth | CHDI Foundation |
Neurozentrum Siloah, Gümligen Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 30.10.2017 | yes | ||||
2024-01674 | The outcome of patients undergoing rescue stenting in Switzerland – An analysis of the Swiss Stroke Registry | personal data/biological material | multicentric | Prof. Marios Psychogios | Universitätsspital Basel |
Universitätsspital Basel, Neuroradiology, Basel Inselspital Bern, Bern Kantonsspital Luzern, Luzern Kantonsspital Aarau, Aarau HUG, Geneve Kantonsspital St. Gallen, St. Gallen Ente Ospedaliero Cantona More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 03.10.2024 | ||||||
2024-01659 | Long term Follow-up of the TREOCAPA (Prophylactic TREatment Of the duCtus Arteriosus in Preterm infants by Acetaminophen) Study | non clinical, involving persons | multicentric | A | Dr. Tobias Mühlbacher | INSERM |
USZ, Zürich HUG, Geneva CHUV, Lausanne |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) | 25.10.2024 | yes | ||||
2024-01656 |
Analysis of health-related personal data from the registry for patients with myeloproliferative neoplasms (MPN) in Switzerland (Swiss MPN Registry) – based on the positive decision of the Ethikkommi More ... |
personal data/biological material | multicentric | Prof. Dr. med. Radek Skoda | Stiftung MPN Forschung Schweiz |
Universitätsspital Basel, Basel Inselspital Bern, Bern Lindenhofgruppe, Bern, Bern Luzerner Kantonsspital, Luzern Kantonsspital Aarau, Aarau Universitätsspital Genf, Genf Kantonsspital St. Gallen, St. More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche G More ... | 09.10.2024 | ||||||
2024-01648 | Florid and pleomorphic lobular carcinoma in situ of the breast: towards an increasingly uniform management. A multicenter observational study | personal data/biological material | multicentric | Maria Luisa Gasparri Prof, MD, PhD | Veneto Institute of Oncology IOV IRCCS |
Dipartimento di Ginecologia e Ostetricia EOC, Ospedale Regionale di Lugano, Lugano Brustchirurgie, Universitätsspital Basel, Basel Brust Zentrum AG, Zürich |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 24.10.2024 | ||||||
2024-01599 | Association of intracranial haemorrhage and sinus venous thrombosis with cerebral vasospasms, delayed cerebral ischemia, shunt dependency and functional outcome | personal data/biological material | multicentric | PD Dr. Isabel Charlotte Hostettler |
Klinik für Neurochirurgie, Kantonsspital St. Gallen, St. Gallen Universitätsspital Basel, Basel |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.10.2024 | |||||||
2024-01598 | A Phase 3, Open-label Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Subjects 12 Months of Age and Older | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Alexander Möller | Vertex Pharmaceuticals Incorporated |
Universitäts-Kinderspital Zürich, Zürich Inselspital, Kinderklinik, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 29.10.2024 | yes | ||