BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2024-D0077 A multi-center randomized controlled trial first in human study to assess the feasibility and safety of adjunctive treatment with the HemoSystem REBOOT in critically ill patientS wiTh sepsis-induced i More ... clinical trial medical devices multicentric C2 Prof. Dr. Jörg Schefold hemotune AG University Hospital Bern, Inselspital, Bern
University Hospital Zurich, Institut für Intensivmedizin, Rämistrasse 100
Kantonale Ethikkommission Bern Kantonale Ethikkommission Zürich 27.09.2024
2024-D0068 The effectiveness of heat treatment on knee pain in patients with osteoarthritis - an international, multicenter clinical investigation.
Prospective, open-label, one-arm, post-market, effectiveness c More ...
clinical trial medical devices multicentric A2 Dr. Marco Marano Angelini Pharma S.p.A., Department of Orthopaedics and Traumatology, Ars Medica Clinic, Lugano
Centro dello Sport Ars Medica, Via Cantonale 38, Manno
Clinica Ars Medica, Via Grumo 16, Gravesano
Clinica Ars Medica, Via Grumo More ...
Comitato etico cantonale Ticino Comitato etico cantonale Ticino 23.09.2024
2024-D0054 CLARITY-Gastric01 - A Phase III Multi-center, Open-label, Sponsor-blinded, Randomized Study of AZD0901 Monotherapy Compared with Investigator’s Choice of Therapy in Second- or Later-Line Adult Partici More ... clinical trial in vitro diagnostic medical devices multicentric C2 Dr med Alexander Siebenhüner AstraZeneca Klinik für Hämatologie und Onkologie Hirslanden Zürich AG , Witellikerstrasse 40, 8032 Zürich
INSELSPITAL Universitätsspital Bern Universitätsklinik für medizinische Onkologie Klinische Forschungseinh More ...
Kantonale Ethikkommission Zürich Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 27.08.2024
2024-D0052 An interventional, prospective study protocol for testing advanced solid tumor FFPE tissue samples to determine patient eligibility for enrollment into Arms B and C, respectively, of Debiopharm’s Phas More ... clinical trial in vitro diagnostic medical devices IVD-MD multicentric C2 Anastasios Stathis Debiopharm International S.A. Istituto Oncologico della Svizzera Italiana - Clinical site, Bellinzona
Inselspital, Universitaetsspital Bern-, Bern
Kantonsspital St. Gallen, Rorschacher Strasse 95
CH-9007 St. Gallen
Comitato etico cantonale Ticino Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS) 28.10.2024
2024-D0051 HYsterectomy with adnexal surgery Procedures with the DEXTER Robotic system clinical trial medical devices multicentric A1 Prof. Dr. med. Michael Mueller Distalmotion SA Inselspital Bern, Bern
Spitäler fmi AG, Unterseen
Kantonsspital Baden, Im Ergel 1
Hirslanden Zurich, Witellikerstrasse 40
Kantonale Ethikkommission Bern Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ 31.07.2024
2024-D0037 The DEXTER-assisted non-emergent and acute cholecystectomy Study clinical trial medical devices multicentric A1 Prof. Dr. med. Stefan Breitenstein Distalmotion SA Kantonsspital Winterthur, Winterthur
Centre Hospitalier Universitaire Vaudois, Rue du Bugnon 46
Hirslanden Zurich, Chirurgisches Zentrum Zürich
Witellikerstrasse 40
Kantonale Ethikkommission Zürich Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Zürich 14.06.2024
2024-D0033 BradycArdia paCemaKer with AV interval modulation for Blood prEssure treAtmenT (BACKBEAT Trial) clinical trial medical devices multicentric C2 Dr. Tardu Özkartal Orchestra Biomed Istituto Cardiocentro Ticino, Lugano
Universitätsspital Bern, Bern
University Hospital Basel, Cardiology
Petersgaben 4
Comitato etico cantonale Ticino Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ 14.10.2024
2024-D0018 A performance evaluation study for the testing of DNA extracted from tumor tissue samples, using the therascreen® KRAS RGQ PCR Kit, from participants with Non-Small Cell Lung Cancer in Lilly’s Clinica More ... clinical trial in vitro diagnostic medical devices multicentric A2 Ulrich Richer Qiagen Manchester Limited University Hospital of Zurich, Zürich
Cantonal Hospital Winterhur, Brauerstrasse 15, Postfach 834
CH-8401 Winterhur
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 28.06.2024
2024-D0011 BIOTRONIK – Safety and Clinical Performance of the Drug Eluting Resorbable Coronary MAGnesium Scaffold System (Freesolve®) in the Treatment of Subjects with de Novo Lesions in Native Coronary Arteries More ... clinical trial medical devices multicentric A2 PD Dr. med. BIOTRONIK AG Juan Fernando, Iglesias
Inselspital Bern, Bern
University Hospital Basel, University Heart Center
Petersgraben 4
Stadtspital Triemli, Klinik für Kardiologie
Birmensdorferstrasse 497
Universitätsspit More ...
Commission Cantonale d'éthique de la recherche Genève (CCER) Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ 07.05.2024
2024-D0006 Advancing Cath Lab Results with FFRangio® Coronary Physiology Assessment: The ALL-RISE Study clinical trial medical devices multicentric A1 Dr. Juan Fernando Iglesias CathWorks Inc. Unité de Cardiologie interventionnelle Service de Cardiologie Hôpitaux Universaires de Genève, Genève
CHUV, Service de cardiologie, Unite de Cardiologie lnter
HFR, Chemin de Pensionnats 2-6
Commission Cantonale d'éthique de la recherche Genève (CCER) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 13.06.2024
2024-D0002 Clinical Performance Study Plan for FoundationOne® Liquid CDx as a Clinical Trial Assay in Clinical Trial GO42144 PLAN-00030, Version 04 clinical trial in vitro diagnostic medical devices multicentric C1 Dr. med. et phil. nat. Simon Häfliger Genentech, Inc. Inselspital Bern, Universitätsklinik für Medizinische Onkologie, Bern
Hôpitaux Universitaires de Genève, Département d'Oncologie, Rue Gabrielle-Perret-Gentil 4
Kantonale Ethikkommission Bern Commission Cantonale d'éthique de la recherche Genève (CCER) 27.03.2024 Study has ended
2024-01959 Serial measurements of C-reactive protein in patients hospitalized for community-acquired pneumonia: is less more? – the SMART-CRP study personal data/biological material multicentric Prof. Dr. med. Carole Elodie Aubert Bern University Hospital Department of General Internal Medicine, Bern University Hospital, Inselspital, Bern
Spitalzentrum Biel, Biel
Kantonale Ethikkommission Bern Kantonale Ethikkommission Bern 30.10.2024
2024-01807 Catheter ABlation of Atrial fibrillation versus atrioventricular nodal ablation with CondUction System pacing in persistent atrial fibrillation and heart failure clinical trial other clinical trials multicentric A Prof Haran Burri HUG HUG, GENEVE
Universitätsklinik für Kardiologie, Bern
Division of Cardiology Spitalstrasse 40,, Basel
University Heart Center, University Hospital Zurich, Zurich
Commission Cantonale d'éthique de la recherche Genève (CCER) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 16.09.2024
2024-01740 Enroll-HD: A Prospective Registry Study in a Global Huntington's Disease Cohort non clinical, involving persons multicentric A Prof. Michael Orth CHDI Foundation Neurozentrum Siloah, Gümligen
Universitätsspital Zürich, Zürich
Kantonale Ethikkommission Bern Kantonale Ethikkommission Zürich 30.10.2017 yes
2024-01674 The outcome of patients undergoing rescue stenting in Switzerland – An analysis of the Swiss Stroke Registry personal data/biological material multicentric Prof. Marios Psychogios Universitätsspital Basel Universitätsspital Basel, Neuroradiology, Basel
Inselspital Bern, Bern
Kantonsspital Luzern, Luzern
Kantonsspital Aarau, Aarau
HUG, Geneve
Kantonsspital St. Gallen, St. Gallen
Ente Ospedaliero Cantona More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 03.10.2024
2024-01659 Long term Follow-up of the TREOCAPA (Prophylactic TREatment Of the duCtus Arteriosus in Preterm infants by Acetaminophen) Study non clinical, involving persons multicentric A Dr. Tobias Mühlbacher INSERM USZ, Zürich
HUG, Geneva
CHUV, Lausanne
Kantonale Ethikkommission Zürich Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) 25.10.2024 yes
2024-01656 Analysis of health-related personal data from the registry for patients with myeloproliferative neoplasms (MPN) in Switzerland (Swiss MPN Registry) –
based on the positive decision of the Ethikkommi More ...
personal data/biological material multicentric Prof. Dr. med. Radek Skoda Stiftung MPN Forschung Schweiz Universitätsspital Basel, Basel
Inselspital Bern, Bern
Lindenhofgruppe, Bern, Bern
Luzerner Kantonsspital, Luzern
Kantonsspital Aarau, Aarau
Universitätsspital Genf, Genf
Kantonsspital St. Gallen, St. More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche G More ... 09.10.2024
2024-01648 Florid and pleomorphic lobular carcinoma in situ of the breast: towards an increasingly uniform management. A multicenter observational study personal data/biological material multicentric Maria Luisa Gasparri Prof, MD, PhD Veneto Institute of Oncology IOV IRCCS Dipartimento di Ginecologia e Ostetricia EOC, Ospedale Regionale di Lugano, Lugano
Brustchirurgie, Universitätsspital Basel, Basel
Brust Zentrum AG, Zürich
Comitato etico cantonale Ticino Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich 24.10.2024
2024-01599 Association of intracranial haemorrhage and sinus venous thrombosis with cerebral vasospasms, delayed cerebral ischemia, shunt dependency and functional outcome personal data/biological material multicentric PD Dr. Isabel Charlotte Hostettler Klinik für Neurochirurgie, Kantonsspital St. Gallen, St. Gallen
Universitätsspital Basel, Basel
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ 10.10.2024
2024-01598 A Phase 3, Open-label Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Subjects 12 Months of Age and Older clinical trial drugs phase 3 multicentric C Prof. Dr. med. Alexander Möller Vertex Pharmaceuticals Incorporated Universitäts-Kinderspital Zürich, Zürich
Inselspital, Kinderklinik, Bern
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern 29.10.2024 yes