| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-D0034 | Fully closed-loop insulin delivery in abdominal surgery: a randomised controlled two-centre trial (CLAB-Study) | clinical trial | medical devices | multicentric | A1 | Prof. Lia Bally | Inselspital, Bern University Hospital, University of Bern |
Inselspital Bern, University Hospital Bern and University of Bern, Bern University Hospital Basel, Anaesthesiology Spitalstrasse 21 |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.06.2022 | ||||
| 2022-D0021 | Evaluation der digitalen Gesundheitsanwendung consilium care™ bei Patienten mit HER2-positivem Brustkrebs während einer Chemotherapie in Kombination mit einer HER2-zielgerichteten Antikörper-Therapie: More ... | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Andreas Trojan | Palleos healthcare GmbH |
OnkoZentrum Zürich, 8038 Zürich Klinik für Gynäkologie, Onkologie, Hämatologie & Immun-therapie Medizini Onkologie Bellevue, Stadelhoferstrasse 42 |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.06.2022 | ||||
| 2022-D0020 | Computed Tomography-Guided Catheter Ablation for Ventricular Tachycardia | clinical trial | medical devices | multicentric | A1 | Dr. Benjamin Berte | University Hospital (CHU) of Bordeaux |
Luzerner Kantonsspital, Luzerner Inselspital Bern, Bern Centre Hospitalier Universitaire Vaudois, Unité des troubles du rythme, service de cardiolog |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern | 16.06.2022 | ||||
| 2022-D0009 | Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients with MINOCA | clinical trial | medical devices | multicentric | A2 | Prof. Dr. Dr. Lorenz Räber | Insel Gruppe AG |
Insel Gruppe AG, Klinik für Kardiologie, Bern Universitätsspital Zürich, Department of Cardiology, University Heart Center |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 27.04.2022 | ||||
| 2022-D0003 | Abutment-free implant for a personalized monolithic zirconia implant crown in the posterior area: A randomized controlled clinical trial | clinical trial | medical devices | multicentric | A1 | Prof.Dr. med.dent Ronald Jung | University of Zurich |
University of Zurich, Center of Dental Medicine, Clinic of Reconstructive Dentistry, Zurich University of Zurich, Center of Dental Medicine Clinic for Oral and Max Private Practice GRIMM Zahnärzte, S More ... |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 01.03.2022 | ||||
| 2022-D0002 | Effects of digitalized differential diagnosis broadening using a computerized diagnostic decision support tool on diagnostic quality in emergency room patients - a multi-centre cluster randomized cros More ... | clinical trial | medical devices | multicentric | C2 | Prof / Wolf / Hautz | Insel Gruppe |
Universitäres Notfallzentrum Erwachsene, Inselspital, Bern Dept. of internal and emergency medicine, Spital Münsingen, Muensingen Dept. of Internal and Emergency Medicine, Spital Tiefenau, Tiefenaustr More ... |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.03.2022 | ||||
| 2022-00922 | Prevalence of post COVID-19 condition in inpatients and outpatients, five and eight months after a COVID-19 infection | non clinical, involving persons | multicentric | A | Prof. Dr. med. Balthasar Hug |
Cantonal Hospital Lucerne, lucerne Notfallpraxis Permanence Bahnhof Luzern, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.06.2022 | ||||||
| 2022-00905 | Prognosis, treatment, and mechanisms in an international pediatric-onset opsoclonus myoclonus ataxia syndrome (POOMAS) database and virtual biobank | personal data/biological material | multicentric | PD Dr.med. Andrea Klein | Boston Children’s Hospital |
UKBB, Basel Inselspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 02.06.2022 | ||||||
| 2022-00725 | A MULTICENTER, SINGLE-ARM, OPEN-LABEL, EXTENSION, ROLLOVER STUDY TO EVALUATE THE LONG-TERM SAFETY AND EFFICACY OF OCRELIZUMAB IN PATIENTS WITH MULTIPLE SCLEROSIS | clinical trial | drugs | phase 3 | multicentric | B | Prof.Dr.med. Tobias Derfuss | F. Hoffmann-La Roche Ltd |
Universitätsspital Basel, Basel Ospedale Regionale di Lugano, Lugano |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Comitato etico cantonale Ticino | 23.06.2022 | |||
| 2022-00686 | Post-marketing Observational Study to explore Vitex-Agnus castus extract Ze 440 in Women with Premenstrual Syndrome associated with Mastodynia and/or Menstrual Cycle Irregularities under real-life con More ... | non clinical, involving persons | multicentric | A | Dr. med. Roger Eltbogen | Max Zeller Söhne AG |
Gynäkologie und Geburtshilfe, 4502 Solothurn Gynäkologie und Geburtshilfe Rossmarktpl. 12, 4502 Solothurn Aeskulp Praxis Baarerstrasse 88, 6300 Zug Ärzte im Zentrum Poststr. 3, 9220 Bischofszell Fried More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 07.06.2022 | |||||
| 2022-00659 | Entwicklung von maschinellen Lernmodellen zur Vorhersage von BMI und Komplikationen in Bariatrischen Operationen (CABS-Study) | personal data/biological material | multicentric | Dr. med. Anas Taha | Clinical Research in Surgery |
GZO Spital Wetzikon, Wetzikon Clarunis, Basel |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.04.2022 | ||||||
| 2022-00621 | MK-1088-002: A Phase 1/Phase 2 Study to Evaluate the Safety and Tolerability of MK-1088 as Monotherapy and in Combination with Pembrolizumab in Participants with Advanced Solid Tumors | clinical trial | drugs | phase 1/2 | multicentric | C | PD Dr. med. Anastasios Stathis | Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona Kantonsspital St. Gallen, St. Gallen Kantonsspital Graubünden, Chur |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 28.06.2022 | |||
| 2022-00603 | SASCIA - Phase III postneoadjuvant study evaluating Sacituzumab Govitecan, an Antibody Drug Conjugate in primary HER2-negative breast cancer patients with high relapse risk after standard neoadjuvant More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Ursina Zürrer | GBG (German Breast Group) |
Kantonsspital Winterthur, Winterthur Brustzentrum, University Hospital Basel, Basel Kantonsspital St. Gallen, St. Gallen Brustzentrum Zürich, Zürich Kantonsspital Graubünden, Chur |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 24.06.2022 | |||
| 2022-00568 | COMBINE 2 - A 52-week study comparing the efficacy and safety of once weekly IcoSema and once weekly semaglutide, both treatment arms with or without oral antidiabetic drugs, in participants with type More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr.med. Stefan Bilz | Novo Nordisk Pharma AG |
Kantonsspital St.Gallen, St.Gallen Luzerner Kantonsspital, Luzern Kantonsspital Olten, Olten DAZZ - Diabetes Adipositas Zentrum Zürich, Zürich |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 09.06.2022 | |||
| 2022-00548 | An international prospective umbrella trial for children with atypical teratoid/rhabdoid tumours (ATRT) including A randomized phase III study evaluating the non-inferiority of three courses of high-d More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Katrin Scheinemann | German Paediatric Oncology Group |
Kantonsspital Aarau, Aarau Inselspital, Bern UKBB, Basel Luzerner Kantonsspital, Luzern Ostschweizer Kinderspital, St. Gallen Universitäts-Kinderspital Zürich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 15.06.2022 | yes | ||
| 2022-00547 | Phase III Clinical Trial for CPX-351 in Myeloid Leukemia in Children with Down Syndrome 2018 | clinical trial | drugs | phase 3 | multicentric | B | Dr. med. Nicole Bodmer | Gesellschaft für Pädiatrische Onkologie und Hämatologie |
University Children's Hospital Zurich, Zurich Inselspital, Bern UKBB, Basel Luzerner Kantonsspital, Luzern Kantonsspital Aarau, Aarau HUG Hôpitaux Universitaires Genève, Geneva Ostschweizer Kinderspit More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... | 14.06.2022 | yes | ||
| 2022-00520 | STAR-LIFE: A POST-MARKET REGISTRY ON MINIJECT | non clinical, involving persons | multicentric | A | Prof. Dr. Jan Darius Unterlauft | iSTAR Medical S.A |
Inselspital Bern (Universitätsklinik für Augenheilkunde, Inselspital), Bern Montchoisi clinic, Lausanne |
Kantonale Ethikkommission Bern | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.06.2022 | |||||
| 2022-00510 | Real-Life Outcomes of adjunct intravitreal Dexamethasone Implant in Patients treated with anti-VEGF drugs for Diabetic Macular Edema and Exudative Age-Related Macular Degeneration | personal data/biological material | multicentric | Prof. Dr. med. Justus G. Garweg |
Berner Augenklinik am Lindenhofspital, Bern Pallas Kliniken AG, Olten VISTA Klinik Binningen, Binningen Kantonsspital Aarau AG, Aarau Centre Ophtalmologique de la Colline, Geneve University Eye Hospit More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de l More ... | 21.06.2022 | |||||||
| 2022-00500 |
A Double Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of PRA023 in Subjects with Systemic Sclerosis Associated with Interstitial Lung Disease (SSc-ILD) |
clinical trial | drugs | phase 2 | multicentric | C | Dr. Oliver Distler | Prometheus Biosciences, Inc. |
Universitätsspital Zürich, Zürich Universität-Spital Bern, Bern Kantonsspital St. Gallen, St. Gallen Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 01.07.2022 | |||
| 2022-00491 | Tele-Assessment: Leveraging Deep Learning to Assess Upper Limb Kinematics after Stroke with Off-the-shelf Webcams | non clinical, involving persons | multicentric | A | Dr. Josef Schönhammer | Universitäts-Spital Zürich |
cereneo - cereneo Foundation, Vitznau Rehabilitation Engineering Laboratory, ETH Zürich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 05.05.2022 | |||||