| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-D0074 | Platelet count and function after usage of two different cell saver devices during cardiac surgery: a randomized controlled bi-center equivalence trial. | clinical trial | medical devices | multicentric | A1 | Prof. Dr. Dr. med. / Gabor / Erdoes | Inselspital Bern, University of Bern |
Inselspital Bern, Bern Hôpitaux Universitaires Genève, HUG, Rue Gabrielle-Perret-Gentil 4 CH-1205 Genève |
Kantonale Ethikkommission Bern | Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.11.2023 | ||||
| 2023-D0063 |
PACIFIC-8: A Phase III, Randomised, Double-blind, Placebo-controlled, Multicentre, International Study of Durvalumab plus Domvanalimab (AB154) in Participants with Locally Advanced (Stage III), Unr More ... |
clinical trial | combination drugs/devices | multicentric | C1 | Dr. med. David König | AstraZeneca AB |
Universitätsspital Basel, Basel Inselspital, Universitätsspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 02.11.2023 | ||||
| 2023-D0052 | CARITY-P: A targeted approach to ensuring CARe and ActivITY persistence in mid- to older-age persons during and after cardiac rehabilitation following a cardiovascular event or intervention | clinical trial | medical devices | multicentric | C2 | Prof. Dr. med. / Matthias / Hermann | Carity AG |
Universitätsspital Zürich, Zurich Kantonsspital St. Gallen, Rorschacher Strasse 95 |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS) | 10.10.2023 | ||||
| 2023-D0043 |
Clinical Performance Study Protocol for PD-L1 IHC 22C3 pharmDx on Non-Squamous Non-Small Cell Lung Cancer Specimens. Supplement to Clinical Trial Protocol DS1062-A-U303. |
clinical trial | in vitro diagnostic medical devices | multicentric | C1 | Dr. med. / Pirmin / Haeuptle | Daiichi Sankyo Inc. |
KSBL Baselland, Liestal Spital STS AG, Thun KSSG, Rorschacher Strasse 95 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS) | 24.08.2023 | ||||
| 2023-D0041 | DEFIANCE - Randomized controlled trial of ClotTriever system versus anticoagulation in deep vein thrombosis | clinical trial | medical devices | multicentric | A2 | Dr. Marc Schindewolf | Inari Medical Europe GmbH |
Inselspital Bern, Bern Luzerner Kantonsspital, Spitalstrasse CH-6000 Luzern 16 |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.09.2023 | ||||
| 2023-D0029 | Robotic minimAlly invaSive inguinAl Hernia rEpAir with Dexter® | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Stefan Breitenstein | Distalmotion SA |
Kantonsspital Winterthur, Winterthur Spital Tiefenau, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 02.05.2023 | ||||
| 2023-D0026 | Renal Denervation in Patients with Recurrent Atrial Fibrillation after Successful Pulmonary Vein Isolation (REDE-AF): a national, multi-centre, prospective, single-arm, pre-to-post treatment, medical- More ... | clinical trial | medical devices | multicentric | C1 | Prof. Dr. med. Laurent Roten | Insel Gruppe AG |
Insel Gruppe AG, Bern Universitätsspital Basel, Petergraben 4 |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.06.2023 | ||||
| 2023-D0024 |
Diagnostic Protocol for VENTANA FGFR2b (FPR2-D) RxDx Assay in Amgen Study 20210098 |
clinical trial | in vitro diagnostic medical devices | multicentric | C2 | Dr. Martin Dave Berger | Ventana Medical Systems, Inc. |
Inselspital, University Hospital Bern, Bern Universitätsspital Basel, Medical Oncology Petersgraben 4 Hôpitaux universitaires de Genève, Service d'oncologie Rue Gabrielle-Perret-Gentil University More ... |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER) | 10.05.2023 | ||||
| 2023-D0023 | Feasibility and efficacy of a transdiagnostic app-based psychological aftercare intervention | clinical trial | medical devices | multicentric | A1 | Dr. Andreea Visla | Universitäre Psychiatrische Kliniken Basel |
Universitäre Psychiatrische Kliniken, Basel Psychiatrische Dienste Aargau, Klinik für Psychiatrie und Psychotherapie Königs |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.05.2023 | ||||
| 2023-D0016 |
A Combination of Low-Energy Ultrasound, Electrical and Magnetic Field Stimulation in Patients with Therapy-Resistant Myofascial Pain Syndrome: A Randomized, Controlled, Double-Blind Multi-Center Stu More ... |
clinical trial | medical devices | multicentric | C2 | PD Dr. med. Christophe Perruchoud | SOBET AG |
Hôpital de La Tour, 1217 Meyrin Salem-Spital Bern, Bern Schmerzklinik Zürich, Wallisellenstr. 301a |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 17.04.2023 | ||||
| 2023-D0011 | Multicentric prospective clinical study to evaluate the Aktiia Optical Blood Pressure Monitoring (OBPM) device compared to standard Home Blood Pressure Monitoring (HBPM) in hypertensive patients when More ... | clinical trial | medical devices | multicentric | A1 | Dr Grégoire WUERZNER | AKTIIA SA |
CHUV, Lausanne HUG, Rue Gabrielle-Perret-Gentil 4, |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.05.2023 | ||||
| 2023-D0006 | MO42720 - INTERVENTIONAL PLATFORM STUDY INVESTIGATING THE IMPACT OF DIGITAL HEALTH SOLUTIONS ON HEALTH OUTCOMES AND HEALTH-CARE RESOURCE UTILIZATION IN PARTICIPANTS RECEIVING SYSTEMIC TREATMENT IN CLI More ... | clinical trial | medical devices | multicentric | A1 | Dr. med. Hasna Bouchaab | Roche Pharma (Schweiz) AG |
Centre hospitalier universitaire vaudois (CHUV), Lausanne Tumor Zentrum Aarau, Rain 34 Hôpitaux universitaires de Genève, Rue Gabrielle-Perret-Gentil 4 Stadtspital Zürich Triemli, Med. Onkologie und H More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.05.2023 | ||||
| 2023-02103 | Physical activity level in hospitalized older adults - a pilot multi-center observational cohort study | non clinical, involving persons | multicentric | A | Dr. phil. Martina Betschart | Ostschweizer Fachhochschule |
Ostschweizer Fachhochschule, St. Gallen Kantonsspital Winterthur, Winterthur |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Zürich | 30.11.2023 | |||||
| 2023-01995 |
Development of a screening algorithm for pathogenic gene fusions from whole slide images of lung adenocarcinoma |
personal data/biological material | multicentric | Professor Bubendorf | F. Hoffman-La Roche Ltd. |
University of Basel, Basel University of Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 07.11.2023 | ||||||
| 2023-01974 | Impact of Tenofovir disoproxil fumarate/Emtricitabine (TDF/FTC) on the gut microbiome and microbiome-mediated toxicity of TDF/FTC in men using event-based HIV Pre-Exposure prophylaxis | non clinical, involving persons | multicentric | A | Dr. med. Julia Notter | Kantonsspital St. Gallen |
Kantonsspital St. Gallen, St. Gallen Universitätsklinik für Infektiologie, Inselspital, Bern |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Bern | 16.11.2023 | |||||
| 2023-01952 | Integrated molecular and clinical profiling to improve disease characterization and outcome prediction in nodal marginal zone lymphoma | personal data/biological material | multicentric | Dr. med. Maria Cristina Pirosa | International Extranodal Lymphoma Study Group (IELSG) |
Oncology Institute of Southern Switzerland and Institute of Oncology Research, Bellinzona University Hospital Basel, Basel Hôpitaux Universitaires Genevois (HUG), Genève Universitätsspital Zürich (USZ More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.11.2023 | ||||||
| 2023-01916 | EXPECT – Patient expectations and their fulfilment in patients with total knee arthroplasty | non clinical, involving persons | multicentric | A | Prof. Dr. med. Markus Arnold | Praxis MEIN KNIE |
Praxis MEIN KNIE, Münchenstein Praxis LEONARDO, Münchenstein |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.11.2023 | |||||
| 2023-01879 | Incidence of acute kidney injury in patients treated with beta-lactam monotherapy or beta-lactam/amikacin combination therapy after autologous hematopoietic stem cell transplantation: a two-center ret More ... | personal data/biological material | multicentric | Prof Dr. med. Michael Osthoff |
Universitätsspital Basel, Basel Inselspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 09.11.2023 | |||||||
| 2023-01801 | Ventilation and oxygenation in acute trauma | personal data/biological material | multicentric | PD Dr Urs Pietsch | KSSG |
KSSG, St Gallen Inselspital Bern, Bern |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Bern | 09.10.2023 | ||||||
| 2023-01791 | A post market clinical study to confirm the performance and safety of the Single Lumen TufTex Embolectomy Catheter on patients undergoing surgical treatment for the removal of arterial emboli and/or t More ... | personal data/biological material | multicentric | Dr med Giorgio Prouse | LeMaitre Vascular, Inc. |
EOC Ospedale Regionale di Lugano, Lugano Inselspital, Bern |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Bern | |||||||