| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-00029 | Appendicitis Global Outcomes Study: Identifying areas for whole systems strengthening in emergency care | personal data/biological material | multicentric | PD Dr. med Sotirios Popeskou | University of Birmingham |
EOC, Lugano Inselspital KinderKliniken, Bern Chirurgie Zentrum St. Anna Klinik St. Anna Ärztehaus Lützelmatt Trakt L St. Anna Strasse 32 Luzern 6006, Luzern LUKS, Luzern UKBB, Basel Spital Thurgau AG More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 15.01.2025 | ||||||
| 2024-D0095 | 20220028 PS_Clinical Performance Study Plan for CD23 IHC Clinical Trial Assay for Combined Study with Amgen Clinical Trial 20220028 | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C2 | Anastasios Stathis | AMGEN |
Istituto Oncologico della Svizzera Italiana, Bellinzona Kantonsspital St.Gallen, Rorschacher Strasse 95 |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS) | 20.11.2024 | ||||
| 2024-D0090 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Optune® (TTFields, 200 kHz) Concomitant with Maintenance Temozolomide and Pembrolizumab Versus Optune® Concomitant with Maintenance Tem More ... | clinical trial | combination drugs/devices | multicentric | C1 | Prof. Dr. med. Michael Weller | Novocure GmbH |
Universitätsspital Zürich, Zürich Universitätsspital Basel, Medical Onkologie Service de neurologie, Centre hospitalier universitaire vaudois (CHUV) R |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.12.2024 | ||||
| 2024-D0077 | A multi-center randomized controlled trial first in human study to assess the feasibility and preliminary safety data of adjunctive treatment with the HemoSystem REBOOT in critically ill patientS wiTh More ... | clinical trial | medical devices | multicentric | C2 | Prof. Dr. Jörg Schefold | hemotune AG |
University Hospital Bern, Inselspital, Bern University Hospital Zurich, Institut für Intensivmedizin, Rämistrasse 100 |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 27.09.2024 | ||||
| 2024-D0069 | RADIUS-HTN Renal Artery DenervatIon Using radial accesS in uncontrolled HyperTensioN | clinical trial | medical devices | multicentric | A2 | Prof. Marco Valgimigli | Shanghai Bioheart Biological Technology Co., Ltd |
1. Istituto Cardiocentro Ticino in Lugano, Lugano University Hospital Basel, Department of Cardiology at University Heart Cente HFR in Fribourg, Department of Cardiology, Chem. des Pensionnats 2/6 |
Comitato etico cantonale Ticino | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.12.2024 | ||||
| 2024-D0068 |
The effectiveness of heat treatment on knee pain in patients with osteoarthritis - an international, multicenter clinical investigation. Prospective, open-label, one-arm, post-market, effectiveness c More ... |
clinical trial | medical devices | multicentric | A2 | Dr. Marco Marano | Angelini Pharma S.p.A., |
Department of Orthopaedics and Traumatology, Ars Medica Clinic, Lugano Centro dello Sport Ars Medica, Via Cantonale 38, Manno Clinica Ars Medica, Via Grumo 16, Gravesano Clinica Ars Medica, Via Grumo More ... |
Comitato etico cantonale Ticino | Comitato etico cantonale Ticino | 23.09.2024 | ||||
| 2024-D0058 | A blinded randomized clinical investigation of RefluxStop™ compared with Nissen fundoplication in the treatment of Gastroesophageal Reflux Disease (GERD). | clinical trial | medical devices | multicentric | A1 | Dr. med, Professor (USC) Jörg Zehetner | Implantica CE Reflux Ltd |
Klinik Beau-Site Hirslanden Bern, Swiss1Chirurgie AG, Bern Inselspital, Universitätsspital Bern, 3010 Bern |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 26.08.2024 | ||||
| 2024-D0054 | CLARITY-Gastric01 - A Phase III Multi-center, Open-label, Sponsor-blinded, Randomized Study of AZD0901 Monotherapy Compared with Investigator’s Choice of Therapy in Second- or Later-Line Adult Partici More ... | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C2 | Dr med Alexander Siebenhüner | AstraZeneca |
Klinik für Hämatologie und Onkologie Hirslanden Zürich AG , Witellikerstrasse 40, 8032 Zürich INSELSPITAL Universitätsspital Bern Universitätsklinik für medizinische Onkologie Klinische Forschungseinh More ... |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève More ... | 27.08.2024 | ||||
| 2024-D0052 | An interventional, prospective study protocol for testing advanced solid tumor FFPE tissue samples to determine patient eligibility for enrollment into Arms B and C, respectively, of Debiopharm’s Phas More ... | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C2 | Anastasios Stathis | Debiopharm International S.A. |
Istituto Oncologico della Svizzera Italiana - Clinical site, Bellinzona Inselspital, Universitaetsspital Bern-, Bern Kantonsspital St. Gallen, Rorschacher Strasse 95 CH-9007 St. Gallen |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS) | 28.10.2024 | ||||
| 2024-D0051 | HYsterectomy with adnexal surgery Procedures with the DEXTER Robotic system | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Michael Mueller | Distalmotion SA |
Inselspital Bern, Bern Spitäler fmi AG, Unterseen Kantonsspital Baden, Im Ergel 1 |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 31.07.2024 | ||||
| 2024-D0037 | The DEXTER-assisted non-emergent and acute cholecystectomy Study | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Stefan Breitenstein | Distalmotion SA |
Kantonsspital Winterthur, Winterthur Centre Hospitalier Universitaire Vaudois, Rue du Bugnon 46 Hirslanden Zurich, Chirurgisches Zentrum Zürich Witellikerstrasse 40 |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Zürich | 14.06.2024 | ||||
| 2024-D0033 | BradycArdia paCemaKer with AV interval modulation for Blood prEssure treAtmenT (BACKBEAT Trial) | clinical trial | medical devices | multicentric | C2 | Dr. Tardu Özkartal | Orchestra Biomed |
Istituto Cardiocentro Ticino, Lugano Universitätsspital Bern, Bern University Hospital Basel, Cardiology Petersgaben 4 |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.10.2024 | ||||
| 2024-D0018 | A performance evaluation study for the testing of DNA extracted from tumor tissue samples, using the therascreen® KRAS RGQ PCR Kit, from participants with Non-Small Cell Lung Cancer in Lilly’s Clinica More ... | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | A2 | Ulrich Richer | Qiagen Manchester Limited |
University Hospital of Zurich, Zürich Cantonal Hospital Winterhur, Brauerstrasse 15, Postfach 834 CH-8401 Winterhur |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 28.06.2024 | ||||
| 2024-D0011 | BIOTRONIK – Safety and Clinical Performance of the Drug Eluting Resorbable Coronary MAGnesium Scaffold System (Freesolve®) in the Treatment of Subjects with de Novo Lesions in Native Coronary Arteries More ... | clinical trial | medical devices | multicentric | A2 | PD Dr. med. | BIOTRONIK AG |
Juan Fernando, Iglesias Inselspital Bern, Bern University of Fribourg, Chemin des Pensionnats 2 University Hospital Basel, University Heart Center Petersgraben 4 Istituto Cardiocentro Ticino, Via Tes More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Comitato etico cantonale Ticino | 07.05.2024 | ||||
| 2024-D0006 | Advancing Cath Lab Results with FFRangio® Coronary Physiology Assessment: The ALL-RISE Study | clinical trial | medical devices | multicentric | A1 | Dr. Juan Fernando Iglesias | CathWorks Inc. |
Unité de Cardiologie interventionnelle Service de Cardiologie Hôpitaux Universaires de Genève, Genève CHUV, Service de cardiologie, Unite de Cardiologie lnter HFR, Chemin de Pensionnats 2-6 |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.06.2024 | ||||
| 2024-D0002 | Clinical Performance Study Plan for FoundationOne® Liquid CDx as a Clinical Trial Assay in Clinical Trial GO42144 PLAN-00030, Version 04 | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C1 | Dr. med. et phil. nat. Simon Häfliger | Genentech, Inc. |
Inselspital Bern, Universitätsklinik für Medizinische Onkologie, Bern Hôpitaux Universitaires de Genève, Département d'Oncologie, Rue Gabrielle-Perret-Gentil 4 |
Kantonale Ethikkommission Bern | Commission Cantonale d'éthique de la recherche Genève (CCER) | 27.03.2024 | Study has ended | |||
| 2024-02477 | Swiss REal World Registry for first line combination treatment of Enfortumab VEdotin And PembroLizumab in metastatic urothelial cancer- REVEAL | personal data/biological material | multicentric | Dr. med. Stefanie Fischer | Kantonsspital St. Gallen |
Klinik für Medizinische Onkologie und Hämatologie, Kantonsspital St. Gallen, St. Gallen Medizinische Onkologie, Inselspital Bern, Bern Onkologie und Hämatologie, Kantonsspital Baden, Baden Onkologie, More ... |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 16.01.2025 | ||||||
| 2024-02322 | Development and Evaluation of a novel A.I.-based Inverse Image Search Engine for Radiology. | personal data/biological material | multicentric | Prof. Dr. med. Alexander Pöllinger | Universitätsinstitut für Diagnostische, Interventionelle und Pädiatrische Radiologie Inselspital Bern |
Universitätsinstitut für Diagnostische, Interventionelle und Pädiatrische Radiologie Inselspital Bern, Bern Lindenhofspital, Bern |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 10.01.2025 | ||||||
| 2024-02297 | Comparison of Proximal Interphalangeal Joint Extensor Lag, Range of Motion, Hand Strength, and Cost-Effectiveness in Conservative vs. Operative Treatment in Closed Extra-articular P1 Fractures. | personal data/biological material | multicentric | Dr. phil. Bernadette Tobler-Ammann | Inselspital Bern |
Inselspital Bern, 3010 Bern Hôpital Pourtalès Maladière 45, 2000 Neuchâtel |
Kantonale Ethikkommission Bern | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.01.2025 | ||||||
| 2024-02290 | Morbidity and mortality of respiratory infections in solid organ transplant recipients | personal data/biological material | multicentric | PD Dr. Laura N. Walti | Universitätsklinik für Infektiologie, Inselspital Bern |
Inselspital Bern, Department of Infectious Diseases, Bern Universitätsspital Basel, 4031 Basel Hôpitaux universitaires de Genève, 1205 Genève KS St. Gallen, St. Gallen CHUV, Lausanne USZ, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 03.12.2024 | ||||||