| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-D0002 | Clinical Performance Study Plan for FoundationOne® Liquid CDx as a Clinical Trial Assay in Clinical Trial GO42144 PLAN-00030, Version 04 | clinical trial | in vitro diagnostic medical devices | multicentric | C1 | Dr. med. et phil. nat. Simon Häfliger | Genentech, Inc. |
Inselspital Bern, Universitätsklinik für Medizinische Onkologie, Bern Hôpitaux Universitaires de Genève, Département d'Oncologie, Rue Gabrielle-Perret-Gentil 4 |
Kantonale Ethikkommission Bern | Commission Cantonale d'éthique de la recherche Genève (CCER) | 27.03.2024 | ||||
| 2024-00470 | A first-in-human, open-label, multicenter Phase I/II study to evaluate the safety and anti-tumor activity of ANV600 as single agent and in combination with pembrolizumab in participants with advanced More ... | clinical trial | drugs | phase 1/2 | multicentric | C | Prof. Dr. Dr. Markus Jörger | Anaveon AG |
Kantonsspital St. Gallen, St. Gallen Ente Ospedaliero Cantonale (EOC), Bellinzona |
Ethikkommission Ostschweiz (EKOS) | Comitato etico cantonale Ticino | 25.04.2024 | |||
| 2024-00413 | Management and outcome of pubic symphysis osteomyelitis: a multicenter retrospective cohort study | non clinical, involving persons | multicentric | A | PD Dr. med. Anna Conen, MSc | Kantonsspital Aarau |
Klinik für Infektiologie und Infektionsprävention, Kantonsspital Aarau, Aarau AG Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.04.2024 | |||||
| 2024-00364 | Handedness and laterality in Plastic Surgery and Outcome - A retrospective, two-center, evaluator-blinded study | personal data/biological material | multicentric | PD Dr. med. Mathias Tremp | TREMP Plastic Surgery AG |
Tremp Plastic Surgery AG, Cham Plastic and Reconstructive Surgery, Geneva |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.04.2024 | ||||||
| 2024-00238 | Inspiratory effort during assisted ventilation: what is normal? | personal data/biological material | multicentric | Francesca Porta | Kantonspital Graubünden |
Kantonspital Graubünden, Chur Ospedale Civico di Lugano, Lugano |
Kantonale Ethikkommission Zürich | Comitato etico cantonale Ticino | 26.03.2024 | ||||||
| 2024-00215 | CAIN457E22101 - An open-label, multicenter study to evaluate the pharmacokinetics, safety and tolerability of intravenous secukinumab infusion in adults with giant cell arteritis (GCA) or polymyalgia More ... | clinical trial | drugs | phase 1 | multicentric | C | Prof. Dr. med. Thomas Daikeler | Novartis Pharma Schweiz AG |
Universitätsspital Basel, Basel Inselspital Bern - Universitätsspital, Bern Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 04.04.2024 | |||
| 2024-00204 |
SAKK 08/14 Subproject Bodycomposition Quantitative assessment of sarcopenia, osteopenia and fat distribution in patients with castration resistant prostate cancer before and during therapy with enzal More ... |
personal data/biological material | multicentric | Prof Dr Med Stefania Maria Rita Rizzo | SAKK |
Clinica di Radiologia EOC, IIMSI, Lugano Kantonsspital Aarau AG, Aarau Kantonsspital Olten, Olten Tumorzentrum Medizinische Onkologie & Palliative Care Luzerner Kantonsspital, Luzern Hôpitaux Universi More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 11.04.2024 | ||||||
| 2024-00142 | Personalized Post-Transplant Risk Prediction with Explainable Machine Learning | personal data/biological material | multicentric | Dr. Jakob Nilsson | University Hospital Zurich |
University Hospital Zurich, Zurich University Hosptial Bern, Bern Universtiy Hospital Basel, Basel University Hosptial Geneva, Geneva Cantonal Hospital St. Gallen, St. Gallen Universtiy Hosptial Lausa More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... | 26.04.2024 | ||||||
| 2024-00130 |
Neurodevelopmental Outcome Registry for CHIldren with complex congenital heart Disease (ORCHID) in Switzerland – Impact of perioperative extracorporeal life support on neurodevelopmental outcome? W More ... |
personal data/biological material | multicentric | Prof. Walter Knirsch | University Children's Hospital Zurich |
University Children's Hospital, Zurich Inselspital Bern, Bern HCUGE, Geneva CHUV, Lausanne University Children's Hospital, Zurich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève More ... | 19.03.2024 | ||||||
| 2024-00075 | Treatment of patellofemoral osteoarthritis with nasal chondrocyte-based engineered cartilage implantation in a randomized, controlled, multi-center phase II clinical trial | clinical trial | transplant products | multicentric | C | PD Dr. Marcus Mumme | Universitätsspital Basel |
Universitätsspital Basel, Basel Inselspital, Bern Crossklinik, Basel Hôpitaux universitaires de Genève, Geneva Ospedale Regionale die Lugano, Lugano Sportclinic Zurich, Zurich Schulthess Klinik Zurich More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico canton More ... | 10.04.2024 | ||||
| 2024-00070 | Short-term effects of an SGLT2 inhibitor on divalent ions in autosomal dominant polycystic kidney disease | clinical trial | drugs | phase 4 | multicentric | B | Prof. Dr. Thomas Fehr |
Department of Internal Medicine Cantonal Hospital Graubuenden, Chur Division of Nephrology, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 12.03.2024 | ||||
| 2024-00055 | DFS-Triage: Eine retrospektive, beobachtende Querschnittsstudie von Patient:innen mit diabetischem Fusssyndrom in drei deutschsprachigen Regionen der Schweiz. | personal data/biological material | multicentric | KD Dr. med. Lea Slahor | QualiCCare |
Luzerner Kantonsspital, Luzern Spital Emmental, Burgdorf Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 14.03.2024 | ||||||
| 2023-D0113 | PEERLESS II - Randomized Controlled Trial of FlowTriever vs. Anticoagulation alone in Pulmonary Embolism | clinical trial | medical devices | multicentric | A1 | Dr. Gregor Leibundgut | Inari Medical Europe GmbH |
Universitätsspital Basel, Basel Inselspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 25.01.2024 | ||||
| 2023-D0111 | A novel endoscopic attachment cap for benign esophageal stricture dilation in children: a randomized, multicentric pilot study. | clinical trial | medical devices | multicentric | A1 | Dr. med. Vasiliki Spyropoulou | University Children’s Hospital Zurich |
University Children’s Hospital, Zurich Universitäts-Kinderspital beider Basel, Spitalstrasse 33, 4056 Basel, Switzerland |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.03.2024 | yes | |||
| 2023-D0103 | Safety and performance of the Biphasic Plate Distal Femur: A multicenter case series | clinical trial | medical devices | multicentric | A1 | Dr.Med Christian Michelitsch | 41medical AG |
Kantonsspital Graubunden, Chur University Hospital Basel, Department of Orthopaedics and Traumatology Unive Universitätsspital Zürich, Rämistrasse 100 |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.01.2024 | ||||
| 2023-D0097 |
CAMBRIA-2 (ClinO-MD) A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next-Generation, Oral Selective Estrogen Receptor Degrader) Versus Standar More ... |
clinical trial | in vitro diagnostic medical devices | multicentric | C2 | Dr. med. Ursina Zürrer-Härdi | AstraZeneca AB |
Kantonsspital Winterthur, Klinik für Medizinische Onkologie und Hämatologie, Winterthur Kantonsspital Baden, Im Ergel Hirslandenklinik St. Anna, Zentrum für Onkologie St. Anna-Strasse 32 Spital Thurg More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Comitato etico cantonale Ticino | 28.03.2024 | ||||
| 2023-D0092 | Mid- oder high-flex Stäbe versus low-flex Stäbe von SpineShape System IV zur Behandlung der degenerativen Lendenwirbelsäule - eine prospektive, multizentrische, randomisiert kontrollierte Non-Inferior More ... | clinical trial | medical devices | multicentric | C3 | Dr. med. Philipp Cathrein | SpineSave AG |
Hirslanden Klinik Linde, Biel Spital Aarberg, Aarberg |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 27.02.2024 | ||||
| 2023-D0078 | Remotely guided tele-ultrasound within the Geneva University Hospitals network | clinical trial | medical devices | multicentric | A1 | Dr. Alexandre Cheviet | Hôpitaux Universitaires de Genève |
Clinique de Crans-Montana, 3963 Crans-Montana Geneva University Hospitals, Chemin du Pont-Bochet 3 |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.04.2024 | ||||
| 2023-D0074 | Platelet count and function after usage of two different cell saver devices during cardiac surgery: a randomized controlled multi-center equivalence trial. | clinical trial | medical devices | multicentric | A1 | Dr. med. / Fabio/ Barattiero | Inselspital Bern, University of Bern |
Inselspital Bern, Bern Hôpitaux Universitaires Genève, HUG, Rue Gabrielle-Perret-Gentil 4 CH-1205 Genève Universiy Hospital Zurich, Institut für Anästhesiologie Rämistrasse 100, 809 |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.11.2023 | ||||
| 2023-D0063 |
PACIFIC-8: A Phase III, Randomised, Double-blind, Placebo-controlled, Multicentre, International Study of Durvalumab plus Domvanalimab (AB154) in Participants with Locally Advanced (Stage III), Unr More ... |
clinical trial | combination drugs/devices | multicentric | C1 | Dr. med. David König | AstraZeneca AB |
Universitätsspital Basel, Basel Inselspital, Universitätsspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 02.11.2023 | ||||