| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-D0034 | Fully closed-loop insulin delivery in abdominal surgery: a randomised controlled two-centre trial (CLAB-Study) | clinical trial | medical devices | multicentric | A1 | Prof. Lia Bally | Inselspital, Bern University Hospital, University of Bern |
Inselspital Bern, University Hospital Bern and University of Bern, Bern University Hospital Basel, Anaesthesiology Spitalstrasse 21 |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.07.2022 | ||||
| 2022-D0024 |
Single Shot Pulmonary Vein Isolation: Comparison of Cryoballoon vs. Pulsed Field Ablation in Patients with Symptomatic Paroxysmal Atrial Fibrillation – A Multi-Center Non-Inferiority Design Clinical More ... |
clinical trial | medical devices | multicentric | A2 | Prof. Dr. Tobias Reichlin | Universitätsklinik für Kardiologie |
Inselspital, Universitätsspital Bern, Bern University Hospital Basel, Department of Cardiology |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.06.2022 | ||||
| 2022-D0021 | Evaluation der digitalen Gesundheitsanwendung consilium care™ bei Patienten mit HER2-positivem Brustkrebs während einer Chemotherapie in Kombination mit einer HER2-zielgerichteten Antikörper-Therapie: More ... | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Andreas Trojan | Palleos healthcare GmbH |
OnkoZentrum Zürich, 8038 Zürich Klinik für Gynäkologie, Onkologie, Hämatologie & Immun-therapie Medizini Onkologie Bellevue, Stadelhoferstrasse 42 |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.06.2022 | ||||
| 2022-D0020 | Computed Tomography-Guided Catheter Ablation for Ventricular Tachycardia | clinical trial | medical devices | multicentric | A1 | Dr. Benjamin Berte | University Hospital (CHU) of Bordeaux |
Luzerner Kantonsspital, Luzerner Inselspital Bern, Bern Centre Hospitalier Universitaire Vaudois, Unité des troubles du rythme, service de cardiolog |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern | 16.06.2022 | ||||
| 2022-D0009 | Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients with MINOCA | clinical trial | medical devices | multicentric | A2 | Prof. Dr. Dr. Lorenz Räber | Insel Gruppe AG |
Insel Gruppe AG, Klinik für Kardiologie, Bern Universitätsspital Zürich, Department of Cardiology, University Heart Center |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 27.04.2022 | ||||
| 2022-D0003 | Abutment-free implant for a personalized monolithic zirconia implant crown in the posterior area: A randomized controlled clinical trial | clinical trial | medical devices | multicentric | A1 | Prof.Dr. med.dent Ronald Jung | University of Zurich |
University of Zurich, Center of Dental Medicine, Clinic of Reconstructive Dentistry, Zurich University of Zurich, Center of Dental Medicine Clinic for Oral and Max Private Practice GRIMM Zahnärzte, S More ... |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 01.03.2022 | ||||
| 2022-D0002 | Effects of digitalized differential diagnosis broadening using a computerized diagnostic decision support tool on diagnostic quality in emergency room patients - a multi-centre cluster randomized cros More ... | clinical trial | medical devices | multicentric | C2 | Prof / Wolf / Hautz | Insel Gruppe |
Universitäres Notfallzentrum Erwachsene, Inselspital, Bern Dept. of internal and emergency medicine, Spital Münsingen, Muensingen Dept. of Internal and Emergency Medicine, Spital Tiefenau, Tiefenaustr More ... |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.03.2022 | ||||
| 2022-01556 | Congenital syphilis in Switzerland: a multi-centre follow-up study, 2010 to 2019 | personal data/biological material | multicentric | PD Dr. Dr. med. Patrick M. Meyer Sauteur | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital Zürich, Zürich Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich Department of Paediatrics, Triemli Hospital Zurich, Zurich Paediatric Infec More ... |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 23.09.2022 | ||||||
| 2022-01402 | Effects of tralokinumab in the skin: an immunologic and molecular investigation | clinical trial | drugs | phase 4 | multicentric | A | Prof. Dr. med. Peter Schmid-Grendelmeier | Dermatologische Klinik, Allergiestation, Universitätsspital Zürich |
Dermatologische Klinik, Universitätsspital Zürich, Zürich Hochgebirgsklinik Davos, CH-7265 Davos Wolfgang |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 27.09.2022 | |||
| 2022-01381 | Benchmarking Surgical Outcomes in Hepatectomies – a retrospective cohort study analyzing outcome parameters after open major anatomic liver resection for all tumors | personal data/biological material | multicentric | Prof. Pierre-Alain Clavien | Universitätsspital Zürich |
University Hospital Zurich, Zürich Universiti Hospitals Geneva, Geneva |
Kantonale Ethikkommission Zürich | Commission Cantonale d'éthique de la recherche Genève (CCER) | 16.09.2022 | ||||||
| 2022-01341 | Clinical characteristics and management of children hospitalized with pyomyositis in Switzerland: a retrospective study (Masterthesis) | personal data/biological material | multicentric | Prof.Ulrich Heininger | UKBB |
UKBB, Basel Inselspital Bern, Bern Kantonsspital Aarau, Aarau Luzerner Kantonsspital, Luzern Hôpitaux Universitaires de Genève, Genève Ostschweizer Kinderspital, St. Gallen Ospedale Regionale di Bell More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 21.09.2022 | ||||||
| 2022-01318 | Randomized, controlled, double-blind, parallel, multicentric study to investigate support of the colonization resistance of the gut microbiota with the synbiotic food supplement Nagasin® after disturb More ... | clinical trial | other clinical trials | multicentric | A | PD Dr. Luc Biedermann | University of Zurich |
University Hospital Zurich, Zurich Inselspital Bern, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 27.09.2022 | ||||
| 2022-01311 | Prospective observational investigation of possible correlations between change in FVC and change in cough or dyspnea scores using the living with pulmonary fibrosis questionnaire (L-PF) between basel More ... | non clinical, involving persons | multicentric | A | PD Dr. med. Katrin Hostettler | Boehringer Ingelheim |
Universitätsspital Basel, Basel Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS) | 14.09.2022 | |||||
| 2022-01294 | Neurostatus-SMARTCARE in comparison to standard Neurostatus-EDSS® – a Swiss multicenter randomized cross-over study | clinical trial | other clinical trials | multicentric | A | PD Dr. med. Marcus D'Souza | Stiftung für Klinische Neuroimmunologie und Neurowissenschaften Basel (RC2NB) |
Universitätsspital Basel, Basel Luzerner Kantonsspital (LUKS), Luzern Reha Rheinfelden, Rheinfelden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.08.2022 | ||||
| 2022-01287 | M20-638: A Phase 3, Open-Label Study to Evaluate Safety and Efficacy of Epcoritamab in Combination with Rituximab and Lenalidomide (R2) compared to R2 in Subjects with Relapsed or Refractory Follicula More ... | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. Felicitas Hitz | AbbVie AG |
Kantonsspital St. Gallen - Klinik für Medizinische Onkologie und Hämatologie, St. Gallen Kantonsspital Aarau - Onkologie, Hämatologie und Transfusionsmedizin, Aarau |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.09.2022 | |||
| 2022-01234 | Association of vaccination status with perceived discrimination in patients with COVID-19 (Masterarbeit) | non clinical, involving persons | multicentric | A | Prof /Sabina/Hunziker | University Hospital Basel |
University Hospital Basel, Basel Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.07.2022 | |||||
| 2022-01211 | Think ‘n’ Move: Evaluating the effects of a concept-guided, personalized, motor-cognitive training in chronic stroke – a RCT | clinical trial | other clinical trials | multicentric | A | Simone Huber | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich Ambulante Reha Triemli Zürich, Zürich Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 19.08.2022 | ||||
| 2022-01155 | 20180146 - A Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of AMG 509 in Subjects With Metastatic Castration-resistant Prostate Cancer | clinical trial | drugs | phase 1 | multicentric | C | Dr. med. Richard Cathomas | Amgen Switzerland AG |
Kantonsspital Graubünden, Department Innere Medizin, Chur Kantonsspital St. Gallen, Klinik für Onkologie Hämatologie, St. Gallen Centre Hospitalier Universitaire Vaudois, Département d'Oncologie, Laus More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.09.2022 | |||
| 2022-01131 | FINE-REAL: A non-interventional study providing insights into the use of finerenone in a routine clinical setting. | non clinical, involving persons | multicentric | A | Prof. Andreas Serra | Bayer AG |
Klinik Hirslanden, Zentrum Nephrologie/Dialyse, Zürich Engeriedspital, Riedweg 15, 3012 Bern, Bern Néphrologie et hémodialyse HFR Fribourg, hôpital fribourgeois, Fribourg Hôpital du Valais – Service d More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Comitato etico cantonale Ticino | 24.08.2022 | |||||
| 2022-01127 | Prospective multicenter observational study evaluating acute lower limb ischemia (PROMOTE-ALI) | personal data/biological material | multicentric | Dr. med. Salome Weiss | Medical University of Innsbruck |
Insel Gruppe AG, Herz Gefäss Zentrum, Universitätsklinik für Gefässchirurgie, Bern Department for vascular surgery, University Hospital Zurich, Zurich Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 20.09.2022 | ||||||