BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2022-D0034 Fully closed-loop insulin delivery in abdominal surgery: a randomised controlled two-centre trial (CLAB-Study) clinical trial medical devices multicentric A1 Prof. Lia Bally Inselspital, Bern University Hospital, University of Bern Inselspital Bern, University Hospital Bern and University of Bern, Bern
University Hospital Basel, Anaesthesiology
Spitalstrasse 21
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ 16.06.2022
2022-D0021 Evaluation der digitalen Gesundheitsanwendung consilium care™ bei Patienten mit HER2-positivem Brustkrebs während einer Chemotherapie in Kombination mit einer HER2-zielgerichteten Antikörper-Therapie: More ... clinical trial medical devices multicentric A1 Prof. Dr. med. Andreas Trojan Palleos healthcare GmbH OnkoZentrum Zürich, 8038 Zürich
Klinik für Gynäkologie, Onkologie, Hämatologie & Immun-therapie
Medizini
Onkologie Bellevue, Stadelhoferstrasse 42
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ 14.06.2022
2022-D0020 Computed Tomography-Guided Catheter Ablation for Ventricular Tachycardia clinical trial medical devices multicentric A1 Dr. Benjamin Berte University Hospital (CHU) of Bordeaux Luzerner Kantonsspital, Luzerner
Inselspital Bern, Bern
Centre Hospitalier Universitaire Vaudois, Unité des troubles du rythme, service de cardiolog
Ethikkommission Nordwest- und Zentralschweiz EKNZ Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern 16.06.2022
2022-D0009 Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients with MINOCA clinical trial medical devices multicentric A2 Prof. Dr. Dr. Lorenz Räber Insel Gruppe AG Insel Gruppe AG, Klinik für Kardiologie, Bern
Universitätsspital Zürich, Department of Cardiology,
University Heart Center
Kantonale Ethikkommission Bern Kantonale Ethikkommission Zürich 27.04.2022
2022-D0003 Abutment-free implant for a personalized monolithic zirconia implant crown in the posterior area: A randomized controlled clinical trial clinical trial medical devices multicentric A1 Prof.Dr. med.dent Ronald Jung University of Zurich University of Zurich, Center of Dental Medicine, Clinic of Reconstructive Dentistry, Zurich
University of Zurich, Center of Dental Medicine
Clinic for Oral and Max
Private Practice GRIMM Zahnärzte, S More ...
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 01.03.2022
2022-D0002 Effects of digitalized differential diagnosis broadening using a computerized diagnostic decision support tool on diagnostic quality in emergency room patients - a multi-centre cluster randomized cros More ... clinical trial medical devices multicentric C2 Prof / Wolf / Hautz Insel Gruppe Universitäres Notfallzentrum Erwachsene, Inselspital, Bern
Dept. of internal and emergency medicine, Spital Münsingen, Muensingen
Dept. of Internal and Emergency Medicine, Spital Tiefenau, Tiefenaustr More ...
Kantonale Ethikkommission Bern Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ 07.03.2022
2022-00922 Prevalence of post COVID-19 condition in inpatients and outpatients, five and eight months after a COVID-19 infection non clinical, involving persons multicentric A Prof. Dr. med. Balthasar Hug Cantonal Hospital Lucerne, lucerne
Notfallpraxis Permanence Bahnhof Luzern, Luzern
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ 23.06.2022
2022-00905 Prognosis, treatment, and mechanisms in an international pediatric-onset opsoclonus myoclonus ataxia syndrome (POOMAS) database and virtual biobank personal data/biological material multicentric PD Dr.med. Andrea Klein Boston Children’s Hospital UKBB, Basel
Inselspital Bern, Bern
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern 02.06.2022
2022-00725 A MULTICENTER, SINGLE-ARM, OPEN-LABEL, EXTENSION, ROLLOVER STUDY TO EVALUATE THE LONG-TERM SAFETY AND EFFICACY OF OCRELIZUMAB IN PATIENTS WITH MULTIPLE SCLEROSIS clinical trial drugs phase 3 multicentric B Prof.Dr.med. Tobias Derfuss F. Hoffmann-La Roche Ltd Universitätsspital Basel, Basel
Ospedale Regionale di Lugano, Lugano
Ethikkommission Nordwest- und Zentralschweiz EKNZ Comitato etico cantonale Ticino 23.06.2022
2022-00686 Post-marketing Observational Study to explore Vitex-Agnus castus extract Ze 440 in Women with Premenstrual Syndrome associated with Mastodynia and/or Menstrual Cycle Irregularities under real-life con More ... non clinical, involving persons multicentric A Dr. med. Roger Eltbogen Max Zeller Söhne AG Gynäkologie und Geburtshilfe, 4502 Solothurn
Gynäkologie und Geburtshilfe Rossmarktpl. 12, 4502 Solothurn
Aeskulp Praxis Baarerstrasse 88, 6300 Zug
Ärzte im Zentrum Poststr. 3, 9220 Bischofszell
Fried More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich 07.06.2022
2022-00659 Entwicklung von maschinellen Lernmodellen zur Vorhersage von BMI und Komplikationen in Bariatrischen Operationen (CABS-Study) personal data/biological material multicentric Dr. med. Anas Taha Clinical Research in Surgery GZO Spital Wetzikon, Wetzikon
Clarunis, Basel
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ 29.04.2022
2022-00621 MK-1088-002: A Phase 1/Phase 2 Study to Evaluate the Safety and Tolerability of MK-1088 as Monotherapy and in Combination with Pembrolizumab in Participants with Advanced Solid Tumors clinical trial drugs phase 1/2 multicentric C PD Dr. med. Anastasios Stathis Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona
Kantonsspital St. Gallen, St. Gallen
Kantonsspital Graubünden, Chur
Comitato etico cantonale Ticino Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich 28.06.2022
2022-00603 SASCIA - Phase III postneoadjuvant study evaluating Sacituzumab Govitecan, an Antibody Drug Conjugate in primary HER2-negative breast cancer patients with high relapse risk after standard neoadjuvant More ... clinical trial drugs phase 3 multicentric C Dr. med. Ursina Zürrer GBG (German Breast Group) Kantonsspital Winterthur, Winterthur
Brustzentrum, University Hospital Basel, Basel
Kantonsspital St. Gallen, St. Gallen
Brustzentrum Zürich, Zürich
Kantonsspital Graubünden, Chur
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich 24.06.2022
2022-00568 COMBINE 2 - A 52-week study comparing the efficacy and safety of once weekly IcoSema and once weekly semaglutide, both treatment arms with or without oral antidiabetic drugs, in participants with type More ... clinical trial drugs phase 3 multicentric C Dr.med. Stefan Bilz Novo Nordisk Pharma AG Kantonsspital St.Gallen, St.Gallen
Luzerner Kantonsspital, Luzern
Kantonsspital Olten, Olten
DAZZ - Diabetes Adipositas Zentrum Zürich, Zürich
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich 09.06.2022
2022-00548 An international prospective umbrella trial for children with atypical teratoid/rhabdoid tumours (ATRT) including A randomized phase III study evaluating the non-inferiority of three courses of high-d More ... clinical trial drugs phase 3 multicentric C Prof. Dr. med. Katrin Scheinemann German Paediatric Oncology Group Kantonsspital Aarau, Aarau
Inselspital, Bern
UKBB, Basel
Luzerner Kantonsspital, Luzern
Ostschweizer Kinderspital, St. Gallen
Universitäts-Kinderspital Zürich, Zürich
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 15.06.2022 yes
2022-00547 Phase III Clinical Trial for CPX-351 in Myeloid Leukemia in Children with Down Syndrome 2018 clinical trial drugs phase 3 multicentric B Dr. med. Nicole Bodmer Gesellschaft für Pädiatrische Onkologie und Hämatologie University Children's Hospital Zurich, Zurich
Inselspital, Bern
UKBB, Basel
Luzerner Kantonsspital, Luzern
Kantonsspital Aarau, Aarau
HUG Hôpitaux Universitaires Genève, Geneva
Ostschweizer Kinderspit More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... 14.06.2022 yes
2022-00520 STAR-LIFE: A POST-MARKET REGISTRY ON MINIJECT non clinical, involving persons multicentric A Prof. Dr. Jan Darius Unterlauft iSTAR Medical S.A Inselspital Bern (Universitätsklinik für Augenheilkunde, Inselspital), Bern
Montchoisi clinic, Lausanne
Kantonale Ethikkommission Bern Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 24.06.2022
2022-00510 Real-Life Outcomes of adjunct intravitreal Dexamethasone Implant in Patients treated with anti-VEGF drugs for Diabetic Macular Edema and Exudative Age-Related Macular Degeneration personal data/biological material multicentric Prof. Dr. med. Justus G. Garweg Berner Augenklinik am Lindenhofspital, Bern
Pallas Kliniken AG, Olten
VISTA Klinik Binningen, Binningen
Kantonsspital Aarau AG, Aarau
Centre Ophtalmologique de la Colline, Geneve
University Eye Hospit More ...
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de l More ... 21.06.2022
2022-00500 A Double Blind, Randomized, Placebo-Controlled Study to Evaluate the
Efficacy and Safety of PRA023 in Subjects with Systemic Sclerosis
Associated with Interstitial Lung Disease (SSc-ILD)
clinical trial drugs phase 2 multicentric C Dr. Oliver Distler Prometheus Biosciences, Inc. Universitätsspital Zürich, Zürich
Universität-Spital Bern, Bern
Kantonsspital St. Gallen, St. Gallen
Universitätsspital Zürich, Zürich
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 01.07.2022
2022-00491 Tele-Assessment: Leveraging Deep Learning to Assess Upper Limb Kinematics after Stroke with Off-the-shelf Webcams non clinical, involving persons multicentric A Dr. Josef Schönhammer Universitäts-Spital Zürich cereneo - cereneo Foundation, Vitznau
Rehabilitation Engineering Laboratory, ETH Zürich, Zürich
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Zürich 05.05.2022