| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-00476 | RESURGE – Randomized Controlled Comparative Phase II Trial on Surgery for Glioblastoma Recurrence | clinical trial | other clinical trials | multicentric | A | Prof. Dr. med. Philippe Schucht | Universitätsklinik für Neurochirurgie, Inselspital Bern |
Universitätsklinik für Neurochirurgie, Inselspital, Bern Kantonsspital Aarau, Aarau Universtitätsspital Basel, Basel Kantonsspital Luzern, Luzern HUG, Geneva Kantonsspital St. Gallen, St. Gallen Osped More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 24.04.2015 | ||||
| 2025-00360 | A Phase 2, Randomized, Blinded, Placebo-Controlled Trial Investigating the Efficacy and Safety of Visugromab versus Placebo, in Combination with Pembrolizumab, Pemetrexed, and Carboplatin, in First-Li More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. Dr. Markus Jörger | CatalYm GmbH |
HOCH Health Ostschweiz, St. Gallen Universitätsspital Basel, Basel HFR Fribourg – Hôpital cantonal, Fribourg |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.04.2025 | |||
| 2025-00293 | 20210181 - A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mell More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Katharina Timper | Amgen Inc. |
Universitätsspital Basel, Basel Hôpitaux Universitaires de Genève, Genève HOCH Health Ostschweiz, Kantonsspital St. Gallen, St. Gallen Stoffwechselzentrum St. Gallen, St. Gallen Universitätsspital Zür More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 03.04.2025 | |||
| 2025-00250 | Magnetic Resonance Imaging in Cancer Patients and Survivors | non clinical, involving persons | multicentric | A | PD Dr. med. Jakob Usemann, MD PhD | UKBB |
University Children's Hospital Basel, UKBB, Basel Inselspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 20.03.2025 | yes | ||||
| 2025-00226 |
MK-8591B-060: A Phase 2b, Randomized, Active-Controlled, Open-Label Clinical Study to Evaluate a Switch to Islatravir (ISL) and Ulonivirine (ULO) Once Weekly in Adults With HIV-1 Virologically Suppr More ... |
clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Enos Bernasconi | Merck Sharp & Dohme LLC |
Ospedale Regionale di Lugano - Civico, Lugano Inselspital Bern, Bern Universitätsspital Basel, Basel Hôpitaux Universitaires de Genève, Genève |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.04.2025 | |||
| 2025-00215 | Retrospective evaluation of age-dependent MRI imaging features of normal variants in shoulder and hip: sublabral recess, sublabral sulcus, sublabral foramen and the buford complex in patients between More ... | personal data/biological material | multicentric | PD Dr. med. Tim Fischer | Klinik für Radiologie und Nuklearmedizin |
Kantonsspital Wintertuhr, Winterthur Kantonsspital St. GAllen, St. Gallen Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 29.04.2025 | ||||||
| 2025-00176 |
MorningLyte A Phase III randomized, open-label, international, multicenter study evaluating the efficacy and safety of mosunetuzumab plus lenalidomide in comparison to anti-CD20 monoclonal antibody p More ... |
clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Carmen de Ramon Ortiz | LYSARC-The Lymphoma Academic Research Organization |
Hôpitaux universitaires de Genève, Service d'hématologie, Genève Spital STS AG, Thun Kantonsspital Baselland, Liestal Kantonsspital Olten, Olten Ente Ospedaliero Cantonale IOSI, Bellinzona Hôpital Can More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... | 23.04.2025 | |||
| 2025-00175 | Precision Sleep Medicine: Hardware and Software Innovations for the Combined Diagnosis and Treatment of Sleep Apnea at the Point-of-Care. | personal data/biological material | multicentric | Dr. med. Matthias Herrmann | Universitätsspital Basel |
Universitätsspital Basel, Basel Universitäts-Kinderspital beider Basel (UKBB), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.03.2025 | ||||||
| 2025-00144 | AVEIR™ Leadless Pacemaker Registry in Europe and MIddle East Region | non clinical, involving persons | multicentric | A | Prof. Dr. med. Michael Kühne | King Fahad Armed Forces Hospital |
Universitätsspital Basel, Universitäres Herzzentrum Basel, Basel Universitätsklinik für Kardiologie Herz Gefäss Zentrum Inselspital, Universitätsspital Bern, Bern Ente Ospedaliero Cantonale, Istituto More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cantonale Ticino | 26.02.2025 | |||||
| 2025-00044 | Prospective pharmacologic characterization of a novel cytomegalovirus-infection prophylaxis (Letermovir) in Pediatric hematopoietic cell transplantation patients using endogenous Coproporphyrin (LetPe More ... | non clinical, involving persons | multicentric | A | Dr. Tamara Diesch-Furlanetto | Uni |
Universitäts-Kinderspital beider Basel, Basel Hôpitaux universitaires de Genève, ’Unité d'oncologie et hématologie pédiatrique, Genf |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Commission Cantonale d'éthique de la recherche Genève (CCER) | 17.02.2025 | yes | ||||
| 2025-00029 | Appendicitis Global Outcomes Study: Identifying areas for whole systems strengthening in emergency care | personal data/biological material | multicentric | PD Dr. med Sotirios Popeskou | University of Birmingham |
EOC, Lugano Inselspital KinderKliniken, Bern Chirurgie Zentrum St. Anna Klinik St. Anna Ärztehaus Lützelmatt Trakt L St. Anna Strasse 32 Luzern 6006, Luzern LUKS, Luzern UKBB, Basel Faculty Visceral S More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 15.01.2025 | ||||||
| 2024-D0119 | Safety and Performance Assessment in Robotic Sacrocolpopexy and Sacrocervicopexy | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Michael Mueller | Distalmotion SA |
Inselspital Bern, Bern Spitäler fmi AG, Unterseen Kantonsspital Baden, Im Ergel 1 |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.04.2025 | ||||
| 2024-D0106 | 20230153 - A Phase 2 Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacokinetics of AMG 193 in Subjects with Methylthioadenosine Phosphorylase (MTAP)-deleted Previously Treated Advanced More ... | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C1 | PD. Dr. med. Dr. phil. Benjamin Kasenda | AMGEN |
Universitätsspital Basel, Medizinische Onkologie, Basel Hôpitaux Universitaire Genève (HUG), Département d’Oncologie, Rue Gabrielle Perret-Gentil 4 HOCH Health Ostschweiz, Kantonsspital St. Gallen Kli More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Commission Cantonale d'éthique de la recherche Genève (CCER) | 07.02.2025 | ||||
| 2024-D0095 | 20220028 PS_Clinical Performance Study Plan for CD23 IHC Clinical Trial Assay for Combined Study with Amgen Clinical Trial 20220028 | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C2 | Martina Imbimbo | AMGEN |
Istituto Oncologico della Svizzera Italiana, Bellinzona HOCH Health Ostschweiz, Rorschacher Strasse 95 |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS) | 20.11.2024 | ||||
| 2024-D0090 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Optune® (TTFields, 200 kHz) Concomitant with Maintenance Temozolomide and Pembrolizumab Versus Optune® Concomitant with Maintenance Tem More ... | clinical trial | combination drugs/devices | multicentric | C1 | Prof. Dr. med. Michael Weller | Novocure GmbH |
Universitätsspital Zürich, Zürich Universitätsspital Basel, Medical Onkologie Service de neurologie, Centre hospitalier universitaire vaudois (CHUV) R |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.12.2024 | ||||
| 2024-D0077 | A multi-center randomized controlled trial first in human study to assess the feasibility and preliminary safety data of adjunctive treatment with the HemoSystem REBOOT in critically ill patientS wiTh More ... | clinical trial | medical devices | multicentric | C2 | Prof. Dr. Jörg Schefold | hemotune AG |
University Hospital Bern, Inselspital, Bern University Hospital Zurich, Institut für Intensivmedizin, Rämistrasse 100 |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 27.09.2024 | ||||
| 2024-D0069 | RADIUS-HTN Renal Artery DenervatIon Using radial accesS in uncontrolled HyperTensioN | clinical trial | medical devices | multicentric | A2 | Prof. Marco Valgimigli | Shanghai Bioheart Biological Technology Co., Ltd |
1. Istituto Cardiocentro Ticino in Lugano, Lugano University Hospital Basel, Department of Cardiology at University Heart Cente HFR in Fribourg, Department of Cardiology, Chem. des Pensionnats 2/6 |
Comitato etico cantonale Ticino | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.12.2024 | ||||
| 2024-D0068 |
The effectiveness of heat treatment on knee pain in patients with osteoarthritis - an international, multicenter clinical investigation. Prospective, open-label, one-arm, post-market, effectiveness c More ... |
clinical trial | medical devices | multicentric | A2 | Dr. Marco Marano | Angelini Pharma S.p.A., |
Department of Orthopaedics and Traumatology, Ars Medica Clinic, Lugano Centro dello Sport Ars Medica, Via Cantonale 38, Manno Clinica Ars Medica, Via Grumo 16, Gravesano Clinica Ars Medica, Via Grumo More ... |
Comitato etico cantonale Ticino | Comitato etico cantonale Ticino | 23.09.2024 | ||||
| 2024-D0058 | A blinded randomized clinical investigation of RefluxStop™ compared with Nissen fundoplication in the treatment of Gastroesophageal Reflux Disease (GERD). | clinical trial | medical devices | multicentric | A1 | Dr. med, Professor (USC) Jörg Zehetner | Implantica CE Reflux Ltd |
Klinik Beau-Site Hirslanden Bern, Swiss1Chirurgie AG, Bern Inselspital, Universitätsspital Bern, 3010 Bern |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 26.08.2024 | ||||
| 2024-D0054 | CLARITY-Gastric01 - A Phase III Multi-center, Open-label, Sponsor-blinded, Randomized Study of AZD0901 Monotherapy Compared with Investigator’s Choice of Therapy in Second- or Later-Line Adult Partici More ... | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C2 | Dr med Alexander Siebenhüner | AstraZeneca |
Klinik für Hämatologie und Onkologie Hirslanden Zürich AG , Witellikerstrasse 40, 8032 Zürich INSELSPITAL Universitätsspital Bern Universitätsklinik für medizinische Onkologie Klinische Forschungseinh More ... |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève More ... | 27.08.2024 | ||||