BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2022-D0034 Fully closed-loop insulin delivery in abdominal surgery: a randomised controlled two-centre trial (CLAB-Study) clinical trial medical devices multicentric A1 Prof. Lia Bally Inselspital, Bern University Hospital, University of Bern Inselspital Bern, University Hospital Bern and University of Bern, Bern
University Hospital Basel, Anaesthesiology
Spitalstrasse 21
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ 08.07.2022
2022-D0024 Single Shot Pulmonary Vein Isolation: Comparison of Cryoballoon vs. Pulsed Field Ablation in Patients with Symptomatic Paroxysmal Atrial Fibrillation
– A Multi-Center Non-Inferiority Design Clinical More ...
clinical trial medical devices multicentric A2 Prof. Dr. Tobias Reichlin Universitätsklinik für Kardiologie Inselspital, Universitätsspital Bern, Bern
University Hospital Basel, Department of Cardiology
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ 30.06.2022
2022-D0021 Evaluation der digitalen Gesundheitsanwendung consilium care™ bei Patienten mit HER2-positivem Brustkrebs während einer Chemotherapie in Kombination mit einer HER2-zielgerichteten Antikörper-Therapie: More ... clinical trial medical devices multicentric A1 Prof. Dr. med. Andreas Trojan Palleos healthcare GmbH OnkoZentrum Zürich, 8038 Zürich
Klinik für Gynäkologie, Onkologie, Hämatologie & Immun-therapie
Medizini
Onkologie Bellevue, Stadelhoferstrasse 42
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ 14.06.2022
2022-D0020 Computed Tomography-Guided Catheter Ablation for Ventricular Tachycardia clinical trial medical devices multicentric A1 Dr. Benjamin Berte University Hospital (CHU) of Bordeaux Luzerner Kantonsspital, Luzerner
Inselspital Bern, Bern
Centre Hospitalier Universitaire Vaudois, Unité des troubles du rythme, service de cardiolog
Ethikkommission Nordwest- und Zentralschweiz EKNZ Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern 16.06.2022
2022-D0009 Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients with MINOCA clinical trial medical devices multicentric A2 Prof. Dr. Dr. Lorenz Räber Insel Gruppe AG Insel Gruppe AG, Klinik für Kardiologie, Bern
Universitätsspital Zürich, Department of Cardiology,
University Heart Center
Kantonale Ethikkommission Bern Kantonale Ethikkommission Zürich 27.04.2022
2022-D0003 Abutment-free implant for a personalized monolithic zirconia implant crown in the posterior area: A randomized controlled clinical trial clinical trial medical devices multicentric A1 Prof.Dr. med.dent Ronald Jung University of Zurich University of Zurich, Center of Dental Medicine, Clinic of Reconstructive Dentistry, Zurich
University of Zurich, Center of Dental Medicine
Clinic for Oral and Max
Private Practice GRIMM Zahnärzte, S More ...
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 01.03.2022
2022-D0002 Effects of digitalized differential diagnosis broadening using a computerized diagnostic decision support tool on diagnostic quality in emergency room patients - a multi-centre cluster randomized cros More ... clinical trial medical devices multicentric C2 Prof / Wolf / Hautz Insel Gruppe Universitäres Notfallzentrum Erwachsene, Inselspital, Bern
Dept. of internal and emergency medicine, Spital Münsingen, Muensingen
Dept. of Internal and Emergency Medicine, Spital Tiefenau, Tiefenaustr More ...
Kantonale Ethikkommission Bern Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ 07.03.2022
2022-01556 Congenital syphilis in Switzerland: a multi-centre follow-up study, 2010 to 2019 personal data/biological material multicentric PD Dr. Dr. med. Patrick M. Meyer Sauteur Universitäts-Kinderspital Zürich Universitäts-Kinderspital Zürich, Zürich
Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich
Department of Paediatrics, Triemli Hospital Zurich, Zurich
Paediatric Infec More ...
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 23.09.2022
2022-01402 Effects of tralokinumab in the skin: an immunologic and molecular investigation clinical trial drugs phase 4 multicentric A Prof. Dr. med. Peter Schmid-Grendelmeier Dermatologische Klinik, Allergiestation, Universitätsspital Zürich Dermatologische Klinik, Universitätsspital Zürich, Zürich
Hochgebirgsklinik Davos, CH-7265 Davos Wolfgang
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 27.09.2022
2022-01381 Benchmarking Surgical Outcomes in Hepatectomies – a retrospective cohort study analyzing outcome parameters after open major anatomic liver resection for all tumors personal data/biological material multicentric Prof. Pierre-Alain Clavien Universitätsspital Zürich University Hospital Zurich, Zürich
Universiti Hospitals Geneva, Geneva
Kantonale Ethikkommission Zürich Commission Cantonale d'éthique de la recherche Genève (CCER) 16.09.2022
2022-01341 Clinical characteristics and management of children hospitalized with pyomyositis in Switzerland: a retrospective study (Masterthesis) personal data/biological material multicentric Prof.Ulrich Heininger UKBB UKBB, Basel
Inselspital Bern, Bern
Kantonsspital Aarau, Aarau
Luzerner Kantonsspital, Luzern
Hôpitaux Universitaires de Genève, Genève
Ostschweizer Kinderspital, St. Gallen
Ospedale Regionale di Bell More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 21.09.2022
2022-01318 Randomized, controlled, double-blind, parallel, multicentric study to investigate support of the colonization resistance of the gut microbiota with the synbiotic food supplement Nagasin® after disturb More ... clinical trial other clinical trials multicentric A PD Dr. Luc Biedermann University of Zurich University Hospital Zurich, Zurich
Inselspital Bern, Bern
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern 27.09.2022
2022-01311 Prospective observational investigation of possible correlations between change in FVC and change in cough or dyspnea scores using the living with pulmonary fibrosis questionnaire (L-PF) between basel More ... non clinical, involving persons multicentric A PD Dr. med. Katrin Hostettler Boehringer Ingelheim Universitätsspital Basel, Basel
Kantonsspital St. Gallen, St. Gallen
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Ostschweiz (EKOS) 14.09.2022
2022-01294 Neurostatus-SMARTCARE in comparison to standard Neurostatus-EDSS® – a Swiss multicenter randomized cross-over study clinical trial other clinical trials multicentric A PD Dr. med. Marcus D'Souza Stiftung für Klinische Neuroimmunologie und Neurowissenschaften Basel (RC2NB) Universitätsspital Basel, Basel
Luzerner Kantonsspital (LUKS), Luzern
Reha Rheinfelden, Rheinfelden
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ 30.08.2022
2022-01287 M20-638: A Phase 3, Open-Label Study to Evaluate Safety and Efficacy of Epcoritamab in Combination with Rituximab and Lenalidomide (R2) compared to R2 in Subjects with Relapsed or Refractory Follicula More ... clinical trial drugs phase 3 multicentric C PD Dr. Felicitas Hitz AbbVie AG Kantonsspital St. Gallen - Klinik für Medizinische Onkologie und Hämatologie, St. Gallen
Kantonsspital Aarau - Onkologie, Hämatologie und Transfusionsmedizin, Aarau
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ 15.09.2022
2022-01234 Association of vaccination status with perceived discrimination in patients with COVID-19 (Masterarbeit) non clinical, involving persons multicentric A Prof /Sabina/Hunziker University Hospital Basel University Hospital Basel, Basel
Kantonsspital Aarau, Aarau
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ 29.07.2022
2022-01211 Think ‘n’ Move: Evaluating the effects of a concept-guided, personalized, motor-cognitive training in chronic stroke – a RCT clinical trial other clinical trials multicentric A Simone Huber Universitätsspital Zürich Universitätsspital Zürich, Zürich
Ambulante Reha Triemli Zürich, Zürich
Kantonsspital Winterthur, Winterthur
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 19.08.2022
2022-01155 20180146 - A Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of AMG 509 in Subjects With Metastatic Castration-resistant Prostate Cancer clinical trial drugs phase 1 multicentric C Dr. med. Richard Cathomas Amgen Switzerland AG Kantonsspital Graubünden, Department Innere Medizin, Chur
Kantonsspital St. Gallen, Klinik für Onkologie Hämatologie, St. Gallen
Centre Hospitalier Universitaire Vaudois, Département d'Oncologie, Laus More ...
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 27.09.2022
2022-01131 FINE-REAL: A non-interventional study providing insights into the use of finerenone in a routine clinical setting. non clinical, involving persons multicentric A Prof. Andreas Serra Bayer AG Klinik Hirslanden, Zentrum Nephrologie/Dialyse, Zürich
Engeriedspital, Riedweg 15, 3012 Bern, Bern
Néphrologie et hémodialyse HFR Fribourg, hôpital fribourgeois, Fribourg
Hôpital du Valais – Service d More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Comitato etico cantonale Ticino 24.08.2022
2022-01127 Prospective multicenter observational study evaluating acute lower limb ischemia (PROMOTE-ALI) personal data/biological material multicentric Dr. med. Salome Weiss Medical University of Innsbruck Insel Gruppe AG, Herz Gefäss Zentrum, Universitätsklinik für Gefässchirurgie, Bern
Department for vascular surgery, University Hospital Zurich, Zurich
Kantonsspital Winterthur, Winterthur
Kantonale Ethikkommission Bern Kantonale Ethikkommission Zürich 20.09.2022