BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2024-D0002 Clinical Performance Study Plan for FoundationOne® Liquid CDx as a Clinical Trial Assay in Clinical Trial GO42144 PLAN-00030, Version 04 clinical trial in vitro diagnostic medical devices multicentric C1 Dr. med. et phil. nat. Simon Häfliger Genentech, Inc. Inselspital Bern, Universitätsklinik für Medizinische Onkologie, Bern
Hôpitaux Universitaires de Genève, Département d'Oncologie, Rue Gabrielle-Perret-Gentil 4
Kantonale Ethikkommission Bern Commission Cantonale d'éthique de la recherche Genève (CCER) 27.03.2024
2024-00238 Inspiratory effort during assisted ventilation: what is normal? personal data/biological material multicentric Francesca Porta Kantonspital Graubünden Kantonspital Graubünden, Chur
Ospedale Civico di Lugano, Lugano
Kantonale Ethikkommission Zürich Comitato etico cantonale Ticino 26.03.2024
2024-00215 CAIN457E22101 - An open-label, multicenter study to evaluate the pharmacokinetics, safety and tolerability of intravenous secukinumab infusion in adults with giant cell arteritis (GCA) or polymyalgia More ... clinical trial drugs phase 1 multicentric C Prof. Dr. med. Thomas Daikeler Novartis Pharma Schweiz AG Universitätsspital Basel, Basel
Inselspital Bern - Universitätsspital, Bern
Kantonsspital St. Gallen, St. Gallen
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern 04.04.2024
2024-00204 SAKK 08/14 Subproject Bodycomposition
Quantitative assessment of sarcopenia, osteopenia and fat distribution in patients with castration resistant prostate cancer before and during therapy with enzal More ...
personal data/biological material multicentric Prof Dr Med Stefania Maria Rita Rizzo SAKK Clinica di Radiologia EOC, IIMSI, Lugano
Kantonsspital Aarau AG, Aarau
Kantonsspital Olten, Olten
Tumorzentrum Medizinische Onkologie & Palliative Care Luzerner Kantonsspital, Luzern
Hôpitaux Universi More ...
Comitato etico cantonale Ticino Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... 11.04.2024
2024-00130 Neurodevelopmental Outcome Registry for CHIldren with complex congenital heart Disease (ORCHID) in Switzerland – Impact of perioperative extracorporeal life support on neurodevelopmental outcome?

W More ...
personal data/biological material multicentric Prof. Walter Knirsch University Children's Hospital Zurich University Children's Hospital, Zurich
Inselspital Bern, Bern
HCUGE, Geneva
CHUV, Lausanne
University Children's Hospital, Zurich
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève More ... 19.03.2024
2024-00075 Treatment of patellofemoral osteoarthritis with nasal chondrocyte-based engineered cartilage implantation in a randomized, controlled, multi-center phase II clinical trial clinical trial transplant products multicentric C PD Dr. Marcus Mumme Universitätsspital Basel Universitätsspital Basel, Basel
Inselspital, Bern
Crossklinik, Basel
Hôpitaux universitaires de Genève, Geneva
Ospedale Regionale die Lugano, Lugano
Sportclinic Zurich, Zurich
Schulthess Klinik Zurich More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico canton More ... 10.04.2024
2024-00070 Short-term effects of an SGLT2 inhibitor on divalent ions in autosomal dominant polycystic kidney disease clinical trial drugs phase 4 multicentric B Prof. Dr. Thomas Fehr Department of Internal Medicine Cantonal Hospital Graubuenden, Chur
Division of Nephrology, University Hospital Zurich, Zurich
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 12.03.2024
2024-00055 DFS-Triage: Eine retrospektive, beobachtende Querschnittsstudie von Patient:innen mit diabetischem Fusssyndrom in drei deutschsprachigen Regionen der Schweiz. personal data/biological material multicentric KD Dr. med. Lea Slahor QualiCCare Luzerner Kantonsspital, Luzern
Spital Emmental, Burgdorf
Kantonsspital St. Gallen, St. Gallen
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern 14.03.2024
2023-D0113 PEERLESS II - Randomized Controlled Trial of FlowTriever vs. Anticoagulation alone in Pulmonary Embolism clinical trial medical devices multicentric A1 Dr. Gregor Leibundgut Inari Medical Europe GmbH Universitätsspital Basel, Basel
Inselspital Bern, Bern
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern 25.01.2024
2023-D0111 A novel endoscopic attachment cap for benign esophageal stricture dilation in children: a randomized, multicentric pilot study. clinical trial medical devices multicentric A1 Dr. med. Vasiliki Spyropoulou University Children’s Hospital Zurich University Children’s Hospital, Zurich
Universitäts-Kinderspital beider Basel, Spitalstrasse 33, 4056 Basel, Switzerland
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ 19.03.2024 yes
2023-D0103 Safety and performance of the Biphasic Plate Distal Femur: A multicenter case series clinical trial medical devices multicentric A1 Dr.Med Christian Michelitsch 41medical AG Kantonsspital Graubunden, Chur
University Hospital Basel, Department of Orthopaedics and Traumatology
Unive
Universitätsspital Zürich, Rämistrasse 100
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ 23.01.2024
2023-D0097 CAMBRIA-2 (ClinO-MD)
A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next-Generation, Oral Selective Estrogen Receptor Degrader) Versus Standar More ...
clinical trial in vitro diagnostic medical devices multicentric C2 Dr. med. Ursina Zürrer-Härdi AstraZeneca AB Kantonsspital Winterthur, Klinik für Medizinische Onkologie und Hämatologie, Winterthur
Kantonsspital Baden, Im Ergel
Hirslandenklinik St. Anna, Zentrum für Onkologie
St. Anna-Strasse 32
Spital Thurg More ...
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Comitato etico cantonale Ticino 28.03.2024
2023-D0092 Mid- oder high-flex Stäbe versus low-flex Stäbe von SpineShape System IV zur Behandlung der degenerativen Lendenwirbelsäule - eine prospektive, multizentrische, randomisiert kontrollierte Non-Inferior More ... clinical trial medical devices multicentric C3 Dr. med. Philipp Cathrein SpineSave AG Hirslanden Klinik Linde, Biel
Spital Aarberg, Aarberg
Kantonale Ethikkommission Bern Kantonale Ethikkommission Bern 27.02.2024
2023-D0074 Platelet count and function after usage of two different cell saver devices during cardiac surgery: a randomized controlled multi-center equivalence trial. clinical trial medical devices multicentric A1 Dr. med. / Fabio/ Barattiero Inselspital Bern, University of Bern Inselspital Bern, Bern
Hôpitaux Universitaires Genève, HUG, Rue Gabrielle-Perret-Gentil 4
CH-1205 Genève
Universiy Hospital Zurich, Institut für Anästhesiologie Rämistrasse 100,
809
Kantonale Ethikkommission Bern Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) 06.11.2023
2023-D0063 PACIFIC-8: A Phase III, Randomised, Double-blind, Placebo-controlled,
Multicentre, International Study of Durvalumab plus
Domvanalimab (AB154) in Participants with Locally Advanced
(Stage III), Unr More ...
clinical trial combination drugs/devices multicentric C1 Dr. med. David König AstraZeneca AB Universitätsspital Basel, Basel
Inselspital, Universitätsspital Bern, Bern
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern 02.11.2023
2023-D0055 Safety and normative data with neos™, in healthy volunteers, children and patient populations with ophthalmological or neurological disease clinical trial medical devices multicentric A1 MD, PhD, Tatiana BREMOVA-ERTL machineMD AG Neurology Inselspital Bern, Bern
Onovis Augenpraxis, Bern
machineMD AG, Weyermannsstrasse 36
Kantonale Ethikkommission Bern Kantonale Ethikkommission Bern 27.09.2023 yes
2023-D0052 CARITY-P: A targeted approach to ensuring CARe and ActivITY persistence in mid- to older-age persons during and after cardiac rehabilitation following a cardiovascular event or intervention clinical trial medical devices multicentric C2 Prof. Dr. med. / Matthias / Hermann Carity AG Universitätsspital Zürich, Zurich
Luzerner Kantonsspital, Herzzentrum
Spitalstrasse
Kantonsspital St. Gallen, Rorschacher Strasse 95
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Ethikkommission Nordwest- und Zentralschweiz EKNZ 10.10.2023
2023-D0043 Clinical Performance Study Protocol for PD-L1 IHC 22C3 pharmDx on Non-Squamous Non-Small Cell Lung Cancer Specimens.

Supplement to Clinical Trial Protocol DS1062-A-U303.
clinical trial in vitro diagnostic medical devices multicentric C1 Dr. med. / Bettina / Seifert Daiichi Sankyo Inc. KSBL Baselland, Liestal
Spital STS AG, Thun
KSSG, Rorschacher Strasse 95
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS) 24.08.2023
2023-D0041 DEFIANCE - Randomized controlled trial of ClotTriever system versus anticoagulation in deep vein thrombosis clinical trial medical devices multicentric A2 Dr. Marc Schindewolf Inari Medical Europe GmbH Inselspital Bern, Bern
Luzerner Kantonsspital, Spitalstrasse
CH-6000 Luzern 16
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ 08.09.2023
2023-D0029 Robotic minimAlly invaSive inguinAl Hernia rEpAir with Dexter® clinical trial medical devices multicentric A1 Prof. Dr. med. Stefan Breitenstein Distalmotion SA Kantonsspital Winterthur, Winterthur
Spital Tiefenau, Bern
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern 02.05.2023 Study has ended