BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2022-D0107 A post-market registry study based on standard clinical care to assess safety and performance of RefluxStop™ in the treatment of Gastroesophageal Reflux Disease (GERD) in general hospital practice. clinical trial medical devices multicentric A1 Dr. med. / Yves / Borbély Implantica CE Reflux Ltd. Inselspital, Bauchzentrum, Bern
Hirslanden Klinik Beau‐Site Bern, Bern
Kantonale Ethikkommission Bern Kantonale Ethikkommission Bern 29.11.2022
2022-D0099 EndurAnt Stent Graft system vs ExcluDer endoprothesis: a global, prospectiVe, rANdomized Clinical trial in sac rEgression clinical trial medical devices multicentric A1 Dr. Sébastien Déglise Medtronic Bakken Research Center Centre hospitalier universitaire vaudois, Lausanne
Luzerner Kantonsspital, Spitalstrasse
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Ethikkommission Nordwest- und Zentralschweiz EKNZ 17.01.2023
2022-D0094 A Prospective, Randomized, Blinded Evaluator, Multicenter, Clinical Study to Evaluate Safety and Effectiveness of TEOSYAL® TPVM versus COMPARATOR for the remodeling of the lower face. clinical trial medical devices multicentric C2 Dr Navid Alizadeh TEOXANE SA Care Geneva Aesthetics, Geneva
Clinique Cleage, Place du Molard 5
Private clinic, Avenue de Champel 24
Clinique des Grangettes, Route de Chêne 110
Clinique de la Croix d’Or, Rue de la Croix-d’Or 7
CHU More ...
Commission Cantonale d'éthique de la recherche Genève (CCER) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) 04.01.2023
2022-D0087 Simplified meal approach study using hybrid closed-loop insulin delivery in youth and young adults with type 1 diabetes – a randomised controlled two-centre crossover trial clinical trial medical devices multicentric A1 Prof. Dr. med. et Dr. phil. Lia Bally Universitätsklinik für Diabetologie, Endokrinologie, klinische Ernährung und Metabolismus Inselspital Bern Universitätsklinik für Diabetologie, Endokrinologie, klinische Ernährung und Metabolismus, Bern
Abteilung Endokrinologie und Diabetologie, Universitäts-Kinderspital Zürich, Abteilung Endokrinologie u More ...
Kantonale Ethikkommission Bern Kantonale Ethikkommission Zürich 25.11.2022 yes
2022-D0086 Prospective Multicenter Confirmatory Clinical Evaluation of Novilase® Interstitial Laser Therapy for the Focal
Destruction of Malignant Breast Tumours ≤15 mm (BR-003)
clinical trial medical devices multicentric A2 Dr Heike Frauchiger-Heuer Novian Health Inc University Hospital Zurich, Zurich
Breast Centre Zurich, Seefeldstrasse 214
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 22.11.2022
2022-D0064 The relevance of the preoperative marker technique for efficient and safe targeted axillary dissection in patients with breast cancer
-A prospective, randomized, multi-center trial
clinical trial medical devices multicentric A1 Dr. Med. Constanze Elfgen Brust-Zentrum Zürich Brust-Zentrum Zürich, Zürich
Brustzentrum Bern Biel, Standort Bern, Bern
Brustzentrum Kantonsspital Baden, Im Ergel 1
Tumor- und Brustzentrum Ostschweiz, Rorschacherstrasse 286
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS), Ethikkommission Nordwest- und Zentralschweiz EKNZ 06.02.2023
2022-D0062 Safety and performance using SMILE with the VisuMax femtosecond laser system optimized for Presbyopia clinical trial medical devices multicentric C2 Dr. Patrick Titzé Carl Zeiss Meditec AG MV SANTE VISION, Sion
MV Sante Vision (Main Site), Rue de Lausanne 27
MV SANTE VISION S.A. (Satellite site), Avenue de Rhodanie 70
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 09.12.2022
2022-D0050 The PROGRESS Trial - A Prospective, Randomized, Controlled Trial to Assess the Management of Moderate Aortic Stenosis by Clinical Surveillance or Transcatheter Aortic Valve Replacement clinical trial medical devices multicentric C1 Prof. Dr. Markus Kasel Edwards Lifesciences LLC Universitäres Herzzentrum, Zürich
Unité de cardiologie structurelle, Département de Médicine
Service de cardiologie
R
Kantonale Ethikkommission Zürich Commission Cantonale d'éthique de la recherche Genève (CCER) 25.11.2022
2022-D0044 ProSPective evaluation of the dIagnostic accuracy of siNe spiN non-contrast flat-dEtectoR CT (FDCT) for the detection of intracranial hemorrhage in Stroke patients - an open labelled, multicenter, non More ... clinical trial medical devices multicentric A2 Prof. Marios-Nikos Psychogios University Hospital Basel University Hospital Basel, Basel
Inselspital Bern, Bern
Kantonsspital Luzern, Sektion für Neuroradiologie
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ 05.07.2022
2022-D0042 Effectiveness of the SpaceOAR Vue System in Subjects with Prostate Cancer being Treated with Stereotactic Body Radiotherapy clinical trial medical devices multicentric A1 Dr Jens Lustenberger Boston Scientific Corporation University Hospital Basel, Basel
Universitätsklinik für Radio-Onkologie, Inselspital, Bern
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern 20.09.2022
2022-D0034 Fully closed-loop insulin delivery in abdominal surgery: a randomised controlled two-centre trial (CLAB-Study) clinical trial medical devices multicentric A1 Prof. Lia Bally Inselspital, Bern University Hospital, University of Bern Inselspital Bern, University Hospital Bern and University of Bern, Bern
University Hospital Basel, Anaesthesiology
Spitalstrasse 21
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ 16.06.2022
2022-D0024 Single Shot Pulmonary Vein Isolation: Comparison of Cryoballoon vs. Pulsed Field Ablation in Patients with Symptomatic Paroxysmal Atrial Fibrillation
– A Multi-Center Non-Inferiority Design Clinical More ...
clinical trial medical devices multicentric A2 Prof. Dr. Tobias Reichlin Universitätsklinik für Kardiologie Inselspital, Universitätsspital Bern, Bern
University Hospital Basel, Department of Cardiology
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ 30.06.2022
2022-D0023 MR42410: A PHASE IIIB, MULTICENTER, RANDOMIZED, VISUAL ASSESSOR-MASKED STUDY OF THE EFFECTIVENESS AND SAFETY OF A 36-WEEK REFILL REGIMEN FOR THE PORT DELIVERY SYSTEM WITH RANIBIZUMAB VS AFLIBERCEPT TR More ... clinical trial combination drugs/devices multicentric C2 Prof. Dr. med. Christian Prünte Roche Pharma (Schweiz) AG Universitätsspital Basel Augenklinik Klinik, 4056 Basel
INSELSPITAL, Universitätsklinik für Augenheilkunde, Bern
Fondation Asile Des Aveugles – Jules Gonin Eye Hospital, Hôpital ophtalmique Jules-Goni More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 26.09.2022
2022-D0021 Evaluation der digitalen Gesundheitsanwendung consilium care™ bei Patienten mit HER2-positivem Brustkrebs während einer Chemotherapie in Kombination mit einer HER2-zielgerichteten Antikörper-Therapie: More ... clinical trial medical devices multicentric A1 Prof. Dr. med. Andreas Trojan Palleos healthcare GmbH See-Spital Horgen, 8810 Horgen
Prolindo, Lindenhofspital, Bern
Klinik für Gynäkologie, Onkologie, Hämatologie & Immun-therapie
Medizini
Onkologie Bellevue, Stadelhoferstrasse 42
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ 14.06.2022
2022-D0020 Computed Tomography-Guided Catheter Ablation for Ventricular Tachycardia clinical trial medical devices multicentric A1 Dr. Benjamin Berte University Hospital (CHU) of Bordeaux Luzerner Kantonsspital, Luzerner
Inselspital Bern, Bern
Centre Hospitalier Universitaire Vaudois, Unité des troubles du rythme, service de cardiolog
Ethikkommission Nordwest- und Zentralschweiz EKNZ Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern 16.06.2022
2022-D0009 Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients with MINOCA clinical trial medical devices multicentric A2 Prof. Dr. Dr. Lorenz Räber Insel Gruppe AG Insel Gruppe AG, Klinik für Kardiologie, Bern
Universitätsspital Zürich, Department of Cardiology,
University Heart Center
Kantonale Ethikkommission Bern Kantonale Ethikkommission Zürich 27.04.2022
2022-D0003 Abutment-free implant for a personalized monolithic zirconia implant crown in the posterior area: A randomized controlled clinical trial clinical trial medical devices multicentric A1 Prof.Dr. med.dent Ronald Jung University of Zurich University of Zurich, Center of Dental Medicine, Clinic of Reconstructive Dentistry, Zurich
University of Zurich, Center of Dental Medicine
Clinic for Oral and Max
Private Practice GRIMM Zahnärzte, S More ...
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 01.03.2022
2022-D0002 Effects of digitalized differential diagnosis broadening using a computerized diagnostic decision support tool on diagnostic quality in emergency room patients - a multi-centre cluster randomized cros More ... clinical trial medical devices multicentric C2 Prof / Wolf / Hautz Insel Gruppe Universitäres Notfallzentrum Erwachsene, Inselspital, Bern
Dept. of internal and emergency medicine, Spital Münsingen, Muensingen
Dept. of Internal and Emergency Medicine, Spital Tiefenau, Tiefenaustr More ...
Kantonale Ethikkommission Bern Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ 07.03.2022
2022-02173 MK-8591A-051: A Phase 3, Randomized, Active-Controlled, Open-Label Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Who Are V More ... clinical trial drugs phase 3 multicentric C PD Dr. med. Dominique Braun Merck Sharp & Dohme Corp. Whitehouse Station, NJ (USA) UniversitätsSpital Zürich (USZ) Klinik für Infektionskrankheiten und Spitalhygiene, Zürich
Inselspital Bern, Universitätsklinik für Infektiologie, Bern
Universitätsspital Basel, Klinik für Infektiolog More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la More ... 24.01.2023
2022-02111 Epidemiology of invasive Candida infections in solid organ transplant recipients over time and risk factor analysis based on the Swiss Transplant Cohort Study. personal data/biological material multicentric Dr Dionysios Neofytos Hôpitaux Universitaires de Genève Hôpitaux universitaires de Genève, Geneva
Insel Spital Bern, Bern
Unispital Basel, Basel
Cantonal Hospital St.Gallen, St Gallen
Centre hospitalier universitaire vaudois, Lausanne
Universitätsspital Zü More ...
Commission Cantonale d'éthique de la recherche Genève (CCER) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 06.12.2022